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| 1 | Role of bile acids in the regulation of the metabolic pathways显示文摘Recent studies have revealed that bile acids(BAs)are not only facilitators of dietary lipid absorption but also important signaling molecules exerting multiple physiological functions.Some major signaling pathways involving the nuclear BAs receptor farnesoid X receptor and the G protein-coupled BAs receptor TGR5/M-BAR have been identified to be the targets of BAs.BAs regulate their own homeostasis via signaling pathways.BAs also affect diverse metabolic pathways including glucose metabolism,lipid metabolism and energy expenditure.This paper suggests the mechanism of controlling metabolism via BA signaling and demonstrates that BA signaling is an attractive therapeutic target of the metabolic syndrome. | Hiroki Taoka Yoko Yokoyama Kohkichi Morimoto Naho Kitamura Tatsuya Tanigaki Yoko Takashina Kazuo Tsubota Mitsuhiro Watanabe | 2016 | World Journal of Diabetes2016，7，13： | 11 |
| 2 | The influence of asymptomatic inflammatory prostatitis on the onset and progression of lower urinary tract symptoms in men with histologic benign prostatic hyperplasia显示文摘Benign prostatic hyperplasia(BPH)is a condition that greatly affects the quality of life of middle-aged and elderly men.Histopathologically,hyperplastic changes frequently occur in the prostate tissue of elderly men,the incidence of which has been reported to reach approximately 80% in men in their 70s.In clinical practice,approximately 25% of men with histologic BPH are assumed to experience lower urinary tract symptoms(LUTS)and receive some kind of treatment.In other words,there are some men with histologic BPH who do not exhibit LUTS.For that reason,many factors,such as the change in hormonal environment,the immune or autoimmune response,the alteration of gene expression,and so on,are thought to affect the onset and progression of LUTS in men with histologic BPH.One such factor that has long drawn attention is the presence of asymptomatic histological inflammation,which very often accompanies symptomatic BPH.Recent studies have suggested that asymptomatic histological inflammation causes repeated destruction,healing,and regeneration of the prostate tissue,leading to the enlargement of prostatic nodules,while at the same time causing stromal tissuepredominant remodeling of the prostate tissue,which can increase urination resistance and result in the condition changing from asymptomatic BPH to symptomatic BPH.In future,the biomolecular clarification of the significance of asymptomatic histological inflammation in the prostate tissue could help develop new treatment strategies for BPH accompanied by LUTS. | Rikiya Taoka Yoshiyuki Kakehi | 2017 | Asian Journal of Urology2017，4，3： | 9 |
| 3 | Anatomy of the hepatic hilar area: the plate system显示文摘 | Yoshifumi Kawarada Bidhan C. Das Hiroki Taoka | 2000 | Journal of Hepato - Biliary - Pancreatic Surgery2000，，6： | 2 |
| 4 | Spatial 10calizations of Mare22 and Maml2 in the magnetosomes of Magnetospirillum magnetotacticum 显示文摘 | Taoka A Asada R Sasaki H | 2006 | J Bacteriol2006，188，11： | 1 |
| 5 | Novel brain ischemic change on MRI : delayed ischemic hyperintensity on T1 weighted images and selective neuronal death in the caudoputamen of rats after brief focal ischemia 显示文摘 | Fujioka M Taoka T Matsuo Y | 1999 | Stroke1999，30，： | 1 |
| 6 | Juvenile Bow Hunter' s Stroke without Hemodynamic Changes 显示文摘 | Saito K Hirano M Taoka T | 2010 | Case Reports2010，3，： | 1 |
| 7 | Role of leukocytes in spinal cord injury in rats显示文摘 | Okajima K | 2000 | J Neurotrauma2000，17，3： | 1 |
| 8 | Superoxide radicals play important roles in the pathogenesis of spinal cord injury显示文摘 | Naruo M Koyanagi E | 1995 | Paraplegia1995，33，8： | 1 |
| 9 | Delayed ischemic hyperintensity on T1-weighted MRI in the caudoputamen and cerebral cortex of humans after spectacular shrinking deficit显示文摘 | Fujioka M Taoka T Hiramatsu KI | 1999 | Stroke1999，30，5： | 1 |
| 10 | Spinal cord injury in the rat显示文摘 | Taoka Y Okajima K | 1998 | Prog Neurobiol1998，56，3： | 1 |
| 11 | The long-term effects of pretreatment with activated protein C in a rat model of compressioninduced spinal cord injury显示文摘 | Schlag MG Hopf R | 2000 | Spinal Cord2000，38，12： | 1 |
| 12 | Novel brain ischemic change on MRI:delayed ischemic hyperintensity on T1-weighted images and selective neuronal death in the caudoputamen of rats after brief focal ischemia显示文摘 | Fujioka M Taoka T Matsuo Y | 1999 | Stroke1999，30，5： | 1 |
| 13 | Spatial localizations of Mam22 and Mam12 in the Magnetosomes of magnetospirillum magnetotacticum显示文摘 | Taoka A Asada R Sasaki H | | 0，，11： | 1 |
| 14 | Clinically mild encephalitis/ encephalopathy with a reversible splenial lesion显示文摘 | H Tada J Takanashi A J. Barkovich H Oba M Maeda H Tsukahara M Suzuki T Yamamoto T Shimono T Ichiyama T Taoka O Sohma H Yoshikawa Y Kohno | 2004 | Neurology2004，，10： | 1 |
| 15 | Expression of a novel biomarker,EPCA,in adenoeareinomas and precancerous lesions in theprostate显示文摘 | Uetsuki H Tsunemori H Taoka R | 2005 | J Urol2005，174，2： | 1 |
| 16 | Clinicopathological features and outcome of hepatic resection for intrahepatic cholangiocarcinoma in Japan显示文摘 | Shuji Isaji Yoshifumi Kawarada Hiroki Taoka Masami Tabata Hideo Suzuki Hajime Yokoi | 1999 | Journal of Hepato - Biliary - Pancreatic Surgery1999，，2： | 1 |
| 17 | Superoxide radicals play important roles in the pathogenesis of spinal cord injury显示文摘 | Taoka Y Naruo M Koyanagi E | | 0，，08： | 1 |
| 18 | Use of AMicrocomputer in Traffic Accident Reconstruction显示文摘 | Taoka George T Reizes Haim Reizes Amit etal | 1989 | ITE Journal ISSN1989，11，： | 1 |
| 19 | Factors influencing visuaization of vertebral metastases on MR imaging versus bone scintigraphy显示文摘 | Taoka T Mayr NA Lee HJ | 2001 | AJR2001，176，6： | 1 |
| 20 | Role of neutrophils in spinal cord injury in the rat显示文摘 | Taoka Y Okajima K Uchiba M | 1997 | Neuroscience1997，79，4： | 1 |
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