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| 1 | Role of Helicobacter pylori infection on nutrition and metabolism显示文摘Helicobacter pylori(H. pylori) is a gram-negative pathogen that is widespread all over the world, infecting more than 50% of the world's population. It is etiologically associated with non-atrophic and atrophic gastritis, peptic ulcer and shows a deep association with primary gastric B-cell lymphoma and gastric adenocarcinoma. Recently, the medical research focused on the modification of the gastric environment induced by H. pylori infection, possibly affecting the absorption of nutrients and drugs as well as the production of hormones strongly implicated in the regulation of appetite and growth. Interestingly, the absorption of iron and vitamin B12 is impaired by H. pylori infection, while infected subjects have lower basal and fasting serum levels of ghrelin and higher concentration of leptin compared to controls. Since leptin is an anorexigenic hormone, and ghrelin stimulates powerfully the release of growth hormone in humans, H. pylori infection may finally induce growth retardation if acquired very early in the childhood and in malnourished children. This review is focused on the nutritional effects of H. pylori infection, such as the reduced bioavailability or the malabsorbption of essential nutrients, and of gastrointestinal hormones, as well as on the relationship between H. pylori and the metabolic syndrome. | Francesco Franceschi Tortora Annalisa Di Rienzo Teresa D'Angelo Giovanna Gianluca Ianiro Scaldaferri Franco Gerardi Viviana Tesori Valentina Lopetuso Loris Riccardo Gasbarrini Antonio | 2014 | World Journal of Gastroenterology2014，20，36： | 11 |
| 2 | Colon cancer stem cells:Controversies and perspectives显示文摘Tumors have long been viewed as a population in which all cells have the equal propensity to form new tumors,the so called conventional stochastic model.The cutting-edge theory on tumor origin and progression,tends to consider cancer as a stem cell disease.Stem cells are actively involved in the onset and maintenance of colon cancer.This review is intended to examine the state of the art on colon cancer stem cells(CSCs),with regard to the recent achievements of basic research and to the corresponding translational consequences.Specific prominence is given to the hypothesized origin of CSCs and to the methods for their identification.The growing understanding of CSC biology is driving the optimization of novel anti-cancer targeted drugs. | Maria Ausiliatrice Puglisi Valentina Tesori Wanda Lattanzi Giovanni Battista Gasbarrini Antonio Gasbarrini | 2013 | World Journal of Gastroenterology2013，19，20： | 5 |
| 3 | Therapeutic Implications of Mesenchymal Stem Cells in Liver Injury显示文摘 | Maria Ausiliatrice Puglisi Valentina Tesori Wanda Lattanzi Anna Chiara Piscaglia Giovanni Battista Gasbarrini Domenico M. D'Ugo Antonio Gasbarrini Ken-ichi Isobe | 2011 | Journal of Biomedicine and Biotechnology2011，，： | 1 |
| 4 | Therapeutic implications of mesenchymal stem cells in liver injury显示文摘 | Puglisi MA Tesori V Lattanzi W | 2011 | J Biomed Biotechn- o12011，2011，86： | 1 |
| 5 | Therapeutic implicationsof mesenchymal stem cells in liver injury显示文摘 | Puglisi MA Tesori V Lattanzi W | 2011 | J Biomed Biotechnol2011，，86： | 1 |
| 6 | Therapeutic Implications of Mesenchymal Stem Cells in Liver Injury显示文摘 | Maria Ausiliatrice Puglisi Valentina Tesori Wanda Lattanzi Anna Chiara Piscaglia Giovanni Battista Gasbarrini Domenico M. D’Ugo Antonio Gasbarrini Ken-ichi Isobe | 2011 | Journal of Biomedicine and Biotechnology2011，，： | 1 |
| 7 | Colon cancer stem: controversies and perspectives显示文摘 | Pu$1isi MA Tesori V Latttmzi W | 2013 | World J Gastroenterol2013，19，20： | 1 |
| 8 | High nitric oxide production, secondary to inducible-nitric oxide syn- thase expression, is essential for regulation of the tumour- initiating properties of colon cancer stem cells显示文摘 | Ausiliatrice Puglisi M Cenciarelli C Tesori V | 2015 | J Pathol2015，236，4： | 1 |
| 9 | Therapeutic implications of mesenchymal stem cells in liver injury显示文摘 | Puglisi MA Tesori V Lattanzi W | 2011 | J Biomed Biotechnol2011，2011，86： | 1 |
| 10 | Lim mineralization protein is involved in the premature calvarial ossification in sporadic craniosynostoses显示文摘 | Wanda Lattanzi Marta Barba Federica Novegno Luca Massimi Valentina Tesori Gianpiero Tamburrini Salvatore Galgano Camilla Bernardini Massimo Caldarelli Fabrizio Michetti Concezio Di Rocco | 2013 | Bone2013，，1： | 1 |
| 11 | Gene expression profiling of two cell lines established from an oval cell derived hepatictu- mor:toward the discovery of a functional signature underlying liver cancer progressin 显示文摘 | Piscaglia AC Saulnier N Tesori V | 2009 | Dig Liver Dis2009，41，3： | 1 |
| 12 | Update on small intestinal stem cells显示文摘Among somatic stem cells, those residing in the intestine represent a fascinating and poorly explored research field. Particularly, somatic stem cells reside in the small intestine at the level of the crypt base, in a constant balance between self-renewal and differentiation. Aim of the present review is to delve into the mechanisms that regulate the delicate equilibrium through which intestinal stem cells orchestrate intestinal architecture. To this aim, special focus will be addressed to identify the integrating signals from the surrounding niche, supporting a model whereby distinct cell populations facilitate homeostatic vs injury-induced regeneration. | Valentina Tesori Maria Ausiliatrice Puglisi Wanda Lattanzi Giovanni Battista Gasbarrini Antonio Gasbarrini | 2013 | World Journal of Gastroenterology2013，19，29： | 0 |
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