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| 1 | Therapeutic alternatives for the treatment of type 1 hepatorenal syndrome: A Delphi technique-based consensus显示文摘AIM To propose several alternatives treatment of type 1 hepatorenal syndrome(HRS-1) what is the most severe expression of circulatory dysfunction on patients with portal hypertension.METHODS A group of eleven gastroenterologists and nephrologists performed a structured analysis of available literature.Each expert was designated to review and answer a question.They generated draft statements for evaluation by all the experts.Additional input was obtained from medical community.In order to reach consensus,a modified three-round Delphi technique method was used.According to United States Preventive Services Task Force criteria,the quality of the evidence and level of recommendation supporting each statement was graded.RESULTS Nine questions were formulated.The available evidence was evaluated considering its quality,number of patients included in the studies and the consistency of its results.The generated questions were answered by the expert panel with a high level of agreement.Thus,a therapeutic algorithm was generated.The role of terlipressin and norepinephrine was confirmed as the pharmacologic treatment of choice.On the other hand the use of the combination of octreotide,midodrine and albumin without vasoconstrictors was discouraged.The role of several other options was also evaluated and the available evidence was explored and discussed.Liver transplantation is considered the definitive treatment for HRS-1.The present consensus is an important effort that intends to organize the available strategies based on the available evidence in the literature,the quality of the evidence and the benefits,adverse effects and availability of the therapeutic tools described.CONCLUSION Based on the available evidence the expert panel was able to discriminate the most appropriate therapeutic alternatives for the treatment of HRS-1. | Juan P Arab Juan C Claro Juan P Arancibia Jorge Contreras Fernando Gomez Cristian Munoz Leyla Nazal Eric Roessler Rodrigo Wolff Marco Arrese Carlos Benítez | 2016 | World Journal of Hepatology2016，8，25： | 3 |
| 2 | SSJD15011600007878显示文摘 | María A. Mejía-Benítez Amélie Bonnefond Lo?c Yengo Marlène Huyvaert Aurélie Dechaume Jesús Peralta-Romero Miguel Klünder-Klünder Jaime García Mena Julia S. El-Sayed Moustafa Mario Falchi Miguel Cruz Philippe Froguel | 2015 | Diabetologia2015，，2： | 2 |
| 3 | Increased antifungal activity of Tfichoderma harzianum transformants that overexpress a 33-kDa chitinase显示文摘 | Limon M C Pintor-Toro J A Benítez T | 1999 | Phytopathol1999，89，： | 1 |
| 4 | High-efficiency LED backlight optics designed with the flow-line method显示文摘 | MINANO J C BEN(I)TEZ P CHAVES J | | 0，，： | 1 |
| 5 | Secondary Forests as Tem- porary Carbon Sinks?The Economic Impact of Accounting Methods on Reforestation Projects in the Tropics显示文摘 | OLSCHEWSKI R BEN~TEZ P C | 2005 | Ecolog- ical Economics2005，55，3： | 1 |
| 6 | Efficient Voice Activity Detection Algorithms Using Long-term Speech Information显示文摘 | Ramirez J Segura J C Benítez C | 2004 | Speech Communication2004，42，3： | 1 |
| 7 | Iterative construction of regular LDPC codes from independent tree-based minimum distance bounds显示文摘 | Psota E Pétez L C | 2011 | IEEE Communications Letters2011，15，3： | 1 |
| 8 | Pneumonia in HIV-infected patients in the HAART era:Incidence,risk,and impact of the pneumococcal vaccination显示文摘 | López-Palomo C Martín-Zamorano M Benítez E | 2004 | J Med Virol2004，72，： | 1 |
| 9 | Na^+ , K^+-ATPase and hormone ouabain: new roles for an old enzyme and an old inhibitor显示文摘 | CONTRERAS R G FLORES-BENI TEZ D FLO-RES-MALDONADO C | 2006 | Cell Mol Biol (Noisy-legrand)2006，52，： | 1 |
| 10 | Allergic vulvovaginitis in infancy:study of a case显示文摘 | GARCIA- AVILES C CARVALHO N FERNANDEZ- BENI- TEZ M | 2001 | Allergol Immunopathol (Madr)2001，29，： | 1 |
| 11 | Multigenic and morphometric differentiation of ground squirrels (Spermophilus, Scuiridae, Rodentia) in Turkey, with a description of a new species显示文摘 | Gunduz I Jaarola M Tez C | 2007 | Mol Phylogenet Evol2007，43，： | 1 |
| 12 | Chamcterization of genetically transformed Sacerevisiae baker's yeasts able to metabolize melibiose显示文摘 | Gasent-Ramí fez J M Codón A C Benl tez T | 1995 | Appl Environ Microb1995，61，6： | 1 |
| 13 | Influence of age and height position on Colombian Guadua angustifolia bamboo me- chanical properties显示文摘 | Juan Francisco Correal D Juliana Arbel~tez C | 2010 | Maderas Ciencia Y Tecnologia2010，12，2： | 1 |
| 14 | Improving analysis of apolar organic compounds by the use of a capillary titania-based column: Application to the direct determination of faecal sterols cholesterol and coprostanol in wastewater samples 显示文摘 | Moliner M Y Herr/tez H R Molins L C | 2010 | Jourl of Chromatography A2010，1217，28： | 1 |
| 15 | Hydroisomerization-cracking of n-octane on heteropolyacid H3PW12O40 supported on ZrO2,SiO2 and carbon effect of Pt incorporation on catalyst performance显示文摘 | Juan C Yori Javier M Grau Viviana M Benl'tez | 2005 | Appl Catal A2005，286，： | 1 |
| 16 | A high-gain, compact, nonimaging concentrator: RXI 显示文摘 | MINANO J C GONZALEZ J C BEN | 1995 | Applied Optics1995，34，4： | 1 |
| 17 | Electrochemically induced self-assembly of alkanethiolate adlayers on carbon steel in aqueous solution显示文摘 | Weber C R Dick L F P Ben 1 tez G | 2009 | Electrochimica Acta2009，54，： | 1 |
| 18 | Bioleaching of chalcopyrite with thermophiles: temperature-pH-ORP dependence显示文摘 | Vilc~tez J Suto K Inoue C | 2008 | International Journal of Mineral Processing2008，88，12： | 1 |
| 19 | Characterization of Various Magnesium Oxides by XRD and 1HMAS NMR Spectroscopy显示文摘 | María Angeles Aramendía José Antonio Benítez Victoriano Borau César Jiménez José Maria Marinas José Rafael Ruiz and Francisco Urbano | 1999 | J Solid State Chem1999，144，1： | 1 |
| 20 | An effective subband OSF-based VAD with noise reduction for robust speech recognition显示文摘 | Ramírez J Segura J C Benítez C | 2005 | IEEE Transactions on Speech and Audio Processing2005，13，6： | 1 |
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