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| 1 | 美洲板栗愈伤组织诱导和植株再生的研究(英文)显示文摘在培养基中添加不同植物生长调节剂(生长素和细胞机动素),对美洲板粟愈伤组织的诱导以及植株再生进行了研究。将试管繁殖的小植株切为长0.5cm的小段作为外植体材料,以木本植物培养基加上3%的蔗糖和0.7%的琼脂作为基本培养基,再加上不同浓度的生长素或细胞机动素作为试验处理。生长素包括IBA,NAA,2,4-D和2,4,5-T;细胞机动素包括kinetin,CPPU,thidiazuron(TDZ)和zeatin。结果表明:外植体的植株再生和愈伤组织诱导百分率以及再生植株的形态发生以及愈伤组织的诱导量在不同的植物生长调节剂处理间和同一植物生长调节剂不同浓度的处理间都存在着显著的差异。促使外植体植株再生百分率最高的细胞机动素为TDZ,其次为CPPU,kinitin和zeatin;促使外植体愈伤组织诱导百分率最好的生长素为2,4,5-T,其次为2,4-D,IBA和NAA. | 杨国臣 鲁重格 Theophilus M. Asante Paul E. Read | 2008 | 吉林农业大学学报2008，30，4： | 5 |
| 2 | 替考拉宁手性柱高效液相色谱法拆分萘哌地尔对映体及分离机制显示文摘在极性有机相条件下用替考拉宁手性柱(Chirobitotic T)直接分离萘哌地尔对映体。考察了三乙胺、醋酸的浓度、比例及柱温、流速对拆分的影响。应用Molecular operation Environment(MOE)软件模拟R/S-萘哌地尔与替考拉宁的相互作用,结合热力学参数探讨其分离机制。结果表明,随着甲醇中三乙胺和醋酸的浓度变小,分离度增大;三乙胺与醋酸的体积比为1∶1时,分离度最好。温度和流速的升高都会使分离度降低。优化后条件为:流动相为甲醇-三乙胺-醋酸(100∶0.002∶0.002,V/V),流速1 mL/min,柱温30℃。在此条件下,萘哌地尔对映体达到了最佳分离,分离度为2.0,理论塔板数达到5100。结合热力学参数和分子模拟结果表明,引起手性识别的主要作用力包括氢键、立体阻碍和π-π作用力。 | 何小梅 姚誉阳 Ndorbor Theophilus 何华 骆雪芳 肖得力 熊雄 | 2013 | 分析化学2013，41，8： | 4 |
| 3 | The effects of co-infection with human parvovirus B19 and Plasmodium falciparum on type and degree of anaemia in Ghanaian children显示文摘Objective:To determin the extent to which parvovirus B19(B19V)and co-infection of B19V and malaria contribute to risk of anaemia in children.Methods:B19V DNA and malaria parasites were screened for 234 children at the PMI,Children's Hospital in Accra.The role of B19V and coinfection with B19V and malaria in anaemia was evaluated by analysing full blood cell counts,malaria and B19V DNA results from these children.Results:The prevalence of B19V,malaria and co-infection with B19V and malaria was 4.7%,41.9%and 2.6%,respectively.Malaria posed a greater risk in the development of mild anaemia compared to severe anaemia(OR=5.28 vrs3.15)whereas B19V posed a higher risk in the development of severe anaemia compared to mild anaemia(OR=4.07 vrs 1.00)from a non-anaemic child.Persons with co-infection with B19V and malaria had 2.23 times the risk(95%CI=0.40-12.54)of developing severe anaemia should they already have a mild anaemia.The degree of anaemia was about three times affected by coinfection(Pillai's trace=0.551,P=0.001)as was affected by malaria alone(Pillai's trace=0.185,P=0.001).B19V alone did not significantly affect the development of anaemia in a non-anaemic child.Microcytic anaemia was associated with B19V and co-infection with B19V and malaria more than normocytic normochromic anaemia.Conclusions:B19V was associated with malaria in cases of severe anaemia.The association posed a significant risk for exacerbation of anaemia in mild anaemic children.B19V and co-infection with B19V and malaria may be associated with microcytic anaemia rather than normocytic normochromic anaemia as seen in cases of B19V infection among persons with red cell abnormalities. | Kwabena Obeng Duedu Kwamena William Coleman Sagoe Patrick Ferdinand Ayeh-Kumi Raymond Bedu Affrim Theophilus Adiku | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，2： | 3 |
| 4 | Osteocyte viability and bone density in cadmium chloride-induced osteoporosis ameliorated with Pilostigma thonningii stem bark-extracted D-3-O-methy-chiroinositol显示文摘Background : This study examined the ameliorative effect of D-3-O-methylchiroinositol, isolated from the stem bark of Piliostigma thonningii, on cadmium chloride-induced osteoporosis in male Wistar rats. Methods : Thirty-six rats were assigned to three treatment groups(n = 12). Group A(2 mL distilled water), group B:(2.5 mg/kg b.w. CdCl_2) and group C:(2.5 mg/kg b.w. CdCl_2 and D-3-O-methyl-chiroinositol 2 mg/kg b.w.). Bone ash, calcium, phosphate, magnesium, and zinc content, as well as bone histological changes were determined at the end of months 1, 2, and 3. Results : There were significant differences( P ≤ 0.05) in the weight of the cervical, tibia, and femoral bones in all groups. The serum concentration of CdCl_2 was significantly different across the three groups with time. There was significant variation( P < 0.005) in the mean bone ash across groups. The concentration of OH-proline was significantly different( P < 0.0001) across groups. There were significant differences( P < 0.0001) in bone calcium, magnesium, zinc, and phosphorus concentrations. Histology revealed high levels of bone mineralisation in the CdCl_2-treated group, indicative of osteoporosis with hypertrophied osteocytes, while the femur of Wistar rats treated with D-3-O-methyl-chiroinositol showed bone trabeculae and viable osteocytes. Conclusion : The study concluded that D-3-O-methyl-chiroinositol extract from Piliostigma thionningii stem bark ameliorated cadmium chloride-induced osteoporosis in male Wistar rats. | Edwin Aihanuwa Uwagie-Ero Clifford Nwabugwu Abiaezute Chinaka O.Nwaehujor Theophilus Okafor Nnaji Eugene Amienwanlen Odigie Oyetunde Kazeem Ekeolu Ohiemi Benjamin Ocheja | 2019 | Animal Models and Experimental Medicine2019，2，1： | 2 |
| 5 | Graft copolymerization of methylmethacrylate onto caesarweed fibers by the potassium permanganate-toluene redox system 显示文摘 | Ighodalo C Eromosele Theophilus J Hamagadu | 1993 | Journal of Applied Polymer Science1993，50，： | 1 |
| 6 | Toxicologi- cal evaluation of expanded shredded tobacco stems 显示文摘 | Theophilus E H Pence D H Meckley D R | 2004 | Food and Chemical Toxicology2004，42，4： | 1 |
| 7 | Further evidence to support a role for urocortin 2 in heart failure显示文摘 | Moxon JV Theophilus I | 2012 | Anadolu Kardiyol Derg2012，12，2： | 1 |
| 8 | Occurrence of female genital tuberculosis among infertile women:a study from a tertiary maternal health care research centre in South India显示文摘 | Bhanothu V Theophilus JP Reddy PK | 2014 | Eur J Clin Microbiol Infect Dis2014，33，11： | 1 |
| 9 | Trends in Prevalence and Outcome of Heart Failure with Preserved Ejection Fraction 显示文摘 | Theophilus EO David OH Regina MH | 2006 | N Engl J Med2006，355，： | 1 |
| 10 | Long‐term survival following laparoscopic and open colectomy for colon cancer: a meta‐analysis of randomized controlled trials显示文摘 | M. Theophilus C. Platell K. Spilsbury | 2014 | Colorectal Dis2014，，3： | 1 |
| 11 | Studies on digestibility of selected legume carbohydrates and its impact on the pH of the gastroin- testinal tract in rats显示文摘 | Geervani P Theophilus F | 1981 | Journal of the Science of Food and Ag- riculture1981，32，： | 1 |
| 12 | Toxicological evalua-tion of expanded shredded tobacco stems显示文摘 | EUGENIA H THEOPHILUS D H PENCE D R | 2004 | Food and Chemical Toxicolo-gy2004，42，： | 1 |
| 13 | Occurrence of female genital tuberculosis among infertile women:a study from a tertiary maternal bealb ere research centre in South India 显示文摘 | Bhanothu V Theophilus JP Reddy PK | 2014 | Eur J Clin Mierobiol & Infect Dis2014，33，11： | 1 |
| 14 | Toxicological evaluation of expanded shredded tobacco stems 显示文摘 | Eugenia H Theophilus D H Pence D R | 2004 | Food and Chemical Toxicology2004，42，： | 1 |
| 15 | Toxicological evaluation of expanded shredded tobac-co stems显示文摘 | Theophilus E H Pence D H Meckley D R | 2004 | Food and Chemical Toxicology2004，42，4： | 1 |
| 16 | Understanding data center traffic characteristics显示文摘 | Theophilus Benson Ashok Anand Aditya Akella Ming Zhang | 2010 | ACM SIGCOMM Computer Communication Review2010，，1： | 1 |
| 17 | Use of endo-ovarian tissue biopsy and pelvic aspirated fluid for the diagnosis of female genital tuberculosis by conventional versus molecular methods显示文摘 | Bhanothu V Theophilus JP Rozati R | 2014 | PLoS One2014，9，98： | 1 |
| 18 | Further evidence to support a role for Urotensin 2 in heart failure 显示文摘 | Joseph V Theophilus I | 2012 | Anadolu Kardiyol Derg2012，12，2： | 1 |
| 19 | Pediatric Road Traffic Accident Deaths Presenting to a Nigerian Referral Center显示文摘 | Osarumwense David Osifo Theophilus Osasumwen Osagie Plus Ehi awaguan Iribhogbe | 2012 | Prehospital and Disaster Medicine2012，272，： | 1 |
| 20 | Toxicological evaluation of expanded shredded tobacco stems 显示文摘 | Theophilus E H | 2004 | Food Toxicol2004，42，： | 1 |
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