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6篇 您的检索式:作者名="Thomas Mock"
    题名 作者 年代 出处 被引量
1Recent advances in sea ice microbiology显示文摘Mock T Thomas D N 2005Environ Microbiol2005,7,5:1
2Recent advances in sea- ice microhiology显示文摘MOCK T THOMAS D N 2005Environmental MicrobioLogy2005,7,5:1
3A self‐enforcing CD 44s/ ZEB 1 feedback loop maintains EMT and stemness properties in cancer cells显示文摘Bogdan‐Tiberius Preca Karolina Bajdak Kerstin Mock Vignesh Sundararajan Jessica Pfannstiel Jochen Maurer Ulrich Wellner Ulrich T. Hopt Tilman Brummer Simone Brabletz Thomas Brabletz Marc P. Stemmler 2015Int. J. Cancer2015,,11:1
4Recent advances in sea ice microbiology显示文摘 Thomas D N 2005Environ Microbiol2005,7,5:1
5Recent advances in sea-ice microbiology 显示文摘Mock T Thomas D N 2005Environmental Microbiology2005,7,5:1
6Significance of differential allelic expression in phenotypic plasticity and evolutionary potential of microbial eukaryotes显示文摘Background:Differential allelic expression(DAE)plays a key role in the regularion of many biological processes,and it may also play a role in adaptive evolution.Recently,environment-dependent DAE has been observed in species of marine phytoplankton,and most remarkably,alleles that showed the highest level of DAE also showed the fastest rate of evolution.Methods:To better understand the role of DAE in adaptive evolution and phenotypic plasticity,we developed a 2-D cellular automata model“DAEsy-World”that builds on the classical Daisyworld model.Results:Simulations show that DAE delineates the evolution of alternative alleles of a gene,enabling the two alleles to adapt to different environmental conditions and sub-functionalize.With DAE,the build-up of genetic polymorphisms within genes is driven by positive selection rather than strict neutral evolution,and this can enhance phenotypic plasticity.Moreover,in sexually reproducing organisms,DAE also increased the standing genetic variation,augmenting a species’adaptive evolutionary potential and ability to respond to fluctuating and/or changing conditions(cf,genetic assimilation).We furthermore show that DAE is likely to evolve in fluctuating environmental conditions.Conclusions:DAE increases the adaptive evolutionary potential of both sexual and asexually reproducing organisms,and it may affect the pattern of nucleotide substitutions of genes.Ben P.Tatman Thomas Mock Taoyang Wu Cock van Oosterhout 2021Quantitative Biology2021,9,4:0
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