5篇
您的检索式：作者名="Thomas Steuber"
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| 1 | Circulating biomarkers for prostate cancer显示文摘 | Thomas Steuber Pauliina Helo Hans Lilja | 2007 | World Journal of Urology2007，，2： | 1 |
| 2 | Strontium Isotope Stratigraphy of Turonian~Campanian Gosau~type Rudist Formations in the Northern Calcareous and Central Alps (Austria and Germany)显示文摘 | | 2001 | Cretaceous Research2001，22，： | 1 |
| 3 | Incremental detection rate of prostate cancer by real‐time elastography targeted biopsies in combination with a conventional 10‐core biopsy in 1024 consecutive patients显示文摘 | Georg Salomon Nils Drews Philippe Autier Ann Beckmann Hans Heinzer Jens Hansen Uwe Michl Thorsten Schlomm Alex Haese Thomas Steuber Markus Graefen Andreas Becker | 2014 | BJU Int2014，，4： | 1 |
| 4 | Cytoreductive radical prostatectomy after chemohormonal therapy in patients with primary metastatic prostate cancer显示文摘Objective:Cytoreductive radical prostatectomy(cRP)has been proposed as local treatment option in metastatic hormone-sensitive prostate cancer(mHSPC)to prevent local complications and potentially improve oncological outcomes.In this study,we examined the feasibility of a multimodal concept with primary chemohormonal therapy followed by cRP and analyzed prostate size reduction under systemic treatment,postoperative complication rates,as well as early postoperative continence.Methods:In this retrospective study,38 patients with mHSPC underwent cRP after primary chemohormonal therapy(3-monthly luteinising hormone-releasing hormone-analogue+six cycles 3-weekly docetaxel 75 mg/m2)at two centers between September 2015 and December 2018.Results:Overall,10(26%)patients had high volume and 28(74%)patients had low volume disease at diagnosis,according to CHAARTED definition.Median prostate-specific antigen(PSA)decreased from 65 ng/mL(interquartile range[IQR]35.0-124.5 ng/mL)pre-chemotherapy to 1 ng/mL(IQR 0.3-1.7 ng/mL)post-chemotherapy.Prostate gland volume was significantly reduced by a median of 50%(IQR 29%-56%)under chemohormonal therapy(p=0.003).Postoperative histopathology showed seminal vesicle invasion in 33(87%)patients and negative surgical margins in 17(45%)patients.Severe complications(Grade 3 according to Clavien-Dindo)were observed in 4(11%)patients within 30 days.Continence was reached in 87%of patients after 1 month and in 92%of patients after 6 months.Median time to castration-resistance from begin of chemohormonal therapy was 41.1 months and from cRP was 35.9 months.Postoperative PSA-nadir≤1 ng/mL versus>1 ng/mL was a significant predictor of time to castration-resistance after cRP(median not reached versus 5.3 months;p<0.0001).Conclusion:We observed a reduction of prostate volume under chemohormonal therapy going along with a low postoperative complication and high early continence rate.However,the oncologic benefit from cRP is still under evaluation. | Christa Babst Thomas Amiel Tobias Maurer Sophie Knipper Lukas Lunger Robert Tauber Margitta Retz Kathleen Herkommer Matthias Eiber Gunhild von Amsbergb Markus Graefen Juergen Gschwend Thomas Steuber Matthias Heck | 2022 | Asian Journal of Urology2022，9，1： | 1 |
| 5 | Multimodal therapy in oligometastatic prostate cancer: A glimpse into the future?显示文摘Dear editor,Since the introduction of radiotracer-labeled prostatespecific membrane antigen(PSMA)targeting positron emission tomography(PET),imaging of prostate cancer(PCa)improved drastically[1,2].Subsequently,metastases may be detected in earlier stages with possible implications on treatment planning[3].Here,we described the multimodal treatment approach on a young patient with newly diagnosed metastatic PCa conducted according to the results of repeated PSMAePET imaging. | Sophie Knipper Gunhild von Amsberg Franziska Stolzenbach Thomas Steuber Matthias Heck Matthias Eiber Christoph Berliner Tobias Maurer | 2021 | Asian Journal of Urology2021，8，2： | 0 |
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