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| 1 | Inhibiting effect of Astragalus polysaccharides on the functions of CD4+CD25^highTreg cells in the tumor microenvironment of human hepatocellular carcinoma显示文摘背景距骨多糖( APS ),从距骨 membranaceus 的主要活跃摘录(繁体中文药用的植物),与学习是在人的 hepatocellular 癌( HCC )的肿瘤微型环境在 Treg 房间的功能上检验 APS 的效果并且在肿瘤地点在 CD4+CD25highTreg 房间识别为反趋化性的活动负责的 APS 的 pharmacologic 机制的礼品的许多 immunomodulatory activities.The 目的被联系 HCC. | LI Qiang BAO Jian-min LI Xiao-li ZHANG Ti SHEN Xiao-hong | 2012 | Chinese Medical Journal2012，，5： | 57 |
| 2 | Shanghai Score: A Prognostic and Adjuvant Treatment-evaluating System Constructed for Chinese Patients with Hepatocellular Carcinoma after Curative Resection显示文摘 | Hui-Chuan Sun Lu Xie Xin-Rong Yang Wei Li Jian Yu Xiao-Dong Zhu Yong Xia Ti Zhang Yang Xu Bo Hu Li-Ping Du Ling-Yao Zeng Jian Ouyang Wei Zhang Tian-Qiang Song Qiang Li Ying-Hong Shi Jian Zhou Shuang-Jian Qiu Qian Liu Yi-Xue Li Zhao-You Tang Yu Shyr Feng Shen Jia Fan | 2017 | Chinese Medical Journal2017，，22： | 15 |
| 3 | A PILOT TRIAL FOR SEVERE ,REFRACTORY SYSTEMIC AUTOIMMUNE DISEASE WITH STEM CELL TRANSPLANTATION显示文摘Objective To evaluate the feasibility, efficacy, and safety of high dose immunosuppressive therapy (HDIT) and autolo- gous hemopoietic stem cell transplantation (HSCT) with CD34+ cell selection in patients with severe, refractory autoim- mune diseases. Methods Twenty-six patients with persistent systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), primary Sjgren’s syndrome (pSS), or systemic sclerosis (SSc) who had been treated unsuccessfully with conventional treatment were enrolled in the trial in Peking Union Medical College Hospital from September 1999 to June 2004. The patients received HDIT with 200 mg/kg cyclophosphamide followed by an infusion of autologous stem cells that were CD34 selected. Disease acti- vity, adverse effect, hemopoietic and immune reconstitution, and time to recurrence of disease were monitored. Results Overall treatment related mortality was 7.7% (2/26) with 1 patient died of cytomegalovirus infection and an- other of severe pneumonia. Relapse occurred in 3 SLE patients (17.6%) in 37, 26, and 19 months posttransplantation respectively, and 1 RA patient in 15 months posttransplantation. SLE Disease Activity Index (SLEDAI) scores of SLE survivors decreased significantly (P < 0.01). RA patients recorded a drop of Disease Activity Score 28 (DAS 28). The pSS patient remained symptoms free up to now, more than 50 months after the transplantation. Conclusion HSCT can be performed relative safely in patients with severe autoimmune disease. Short-term effect of HSCT is promising. However treatment related mortality and relapse were observed in a subset of patients. | Xiao-mei Leng Yan Zhao Dao-bing Zhou Huifen Situ Tai-sheng Li Ti Shen Yong-qiang Zhao Xiao-feng Zeng Feng-chun Zhang Yi Dong Fu-lin Tang | 2005 | Chinese Medical Sciences Journal2005，20，3： | 4 |
| 4 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 5 | Clinical Significance of Lymph Node Metastasis in Patients Undergoing Partial Hepatectomy for Hepatocellular Carcinoma显示文摘 | Shen Xiaohong Li Huikai Wang Feng Zhang Ti Cui Yunlong Li Qiang | 2010 | World Journal of Surgery2010，，5： | 1 |
| 6 | A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection 显示文摘 | Pollin TI Damcott CM Shen H | 2008 | Science2008，322，5908： | 1 |
| 7 | Sodium selenite induces apoptosis in acute promyelocytic leukemia-derived NB4 cells by a caspase-3-dependent mechanism and a redox pathway different from that of arsenic trioxide显示文摘 | Lu Zuo Jian Li Yang Yang Xuan Wang Ti Shen Cai-min Xu Zhi-nan Zhang | 2004 | Annals of Hematology2004，，12： | 1 |
| 8 | A null mutation in human APOC3 con- fers a favorable plasma lipid profile and apparent cardioprotection显示文摘 | Pollin TI Damcott CM Shen H | 2008 | Science2008，322，5908： | 1 |
| 9 | Reexamining the Relations between Socio-De- mographic Characteristics and Individual Environmental Con- cern: Evidence from Shanghai Data 显示文摘 | Shen J TI Saijo | 2008 | Journal of Environmen- tal Psychology2008，28，： | 1 |
| 10 | Cardioprotection Favorable Plasma Lipid Profile and Apparent Confers a APOC3 A Null Mutation in Human显示文摘 | Pollin TI Damcott CM Shen H | 2008 | Science2008，322，5908： | 1 |
| 11 | A null mutation in human APOC 3 confers a favorable plasma lipid profile and apparent cardioprotection显示文摘 | Pollin TI Damcott CM Shen H | | 0，，5908： | 1 |
| 12 | A null mutation in human apo C3 confers a favorable plasma lipid profile and apparent cardio- protection 显示文摘 | Pollin TI Damcott CM Shen H | 2008 | Seience2008，322，5908： | 1 |
| 13 | A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent car- dioprotection显示文摘 | Pollin TI Damcott CM Shen H | 2008 | Science2008，322，5908： | 1 |
| 14 | Thienopyridine use after coronary stenting in low income patients enrolled in medicare part D receiving maintenance dialysis显示文摘 | Chang TI Montez-Rath ME Shen JI | 2014 | J Am Heart Assoc2014，3，5： | 1 |
| 15 | Aortic aneurysm and chronic disseminated intravascular coagulation: a retrospective study of 235 patients显示文摘长期的传播 intravascular 凝结(DIC ) 是大动脉的动脉瘤(AA ) 的稀罕却破坏的复杂并发症。这研究与联系 AA 的长期的 DIC (AA-DIC ) 调查了病人的临床的表明,实验室调查结果,和治疗并且探索了 AA-DIC 的机制,持续时间,和治疗学的反应。我们回顾地考察了病人们在在 2009 年 9 月和 2015 年 1 月之间的北京联合医学院医院承认了的 235 AA 的医药记录。没有 DIC (non-DIC ) ,病人与 DIC (AA-DIC ) 和那些作为那些被分类。AA-DIC 组比 non-DIC 组显示出女病人和一堂显著地更长的 AA 疾病功课的一个显著地更高的比例。介绍墙壁的血栓症,把的动脉瘤, AA 的家庭历史,和糖尿病更经常显著地比 non-DIC 病人做了的 AA-DIC 病人。而且,多重回归分析表明性,墙壁的血栓,动脉瘤类型,糖尿病,和 stent 外科是为 AA-DIC 病人的可能的独立风险因素。52 (22.1%) 病人们介绍了 AA-DIC。在这些病人之中, 43 有非典型的 DIC, 9 有典型 DIC;后者的死亡率是 22.2% 。有典型 DIC 的病人的吝啬的年龄比有非典型的 DIC 的病人的显著地高。非典型的 DIC 病人也介绍了改变度的反常凝结混乱。而且,肝磷脂或 low-molecular-weight 肝磷脂与 AA 和典型 DIC 在病人改进了临床的症状和实验室参数。因此,长期的 DIC 应该与 AA 在病人被考虑。 | Yun Zhang Chen Li Min Shen Bao Liu Xuejun Zeng Ti Shen | 2017 | Frontiers of Medicine2017，11，1： | 1 |
| 16 | Liquid-liquid extraction of lysozyme using a dye-modified ionic liquid 显示文摘 | Tzeng Yu-ping Shen Ching-wei Yu Tiing | 2008 | Journal of Chromatography A2008，1193，12： | 1 |
| 17 | Impaired Erythropoietin Response to Anemia in Patients with Lymphocytic Malignancies显示文摘Patients with lymphocytic malignancies like Non-Hodgkin's lymphoma (NHL), multiple myeloma (MM), and chronic lymphocytic leukemia (CLL) are often complicated with anemia. In this prospective study, we devised a carefully controlled erythropoietin (Epo) level measurement in anemic or non-anemic patients with lymphocytic malignancies, in order to determine whether the response of Epo was decreased in anemic patients. | Bing Han Yuan-kai Shi Jun Zhu Xiao-hui He Ning-jing Lin Shu-lan Li Ti Shen | 2007 | Chinese Medical Sciences Journal2007，22，3： | 1 |
| 18 | Distinct DNA methylation profiles in malignant mesothelioma lung adenocarcinoma,and non-tumor lung显示文摘 | Tsou JA Shen LY Siegmund KD Long TI Laird PW Seneviratne CK | 2005 | Lung Cancer2005，47，： | 1 |
| 19 | Identification of a Novel Mutation in Solute Carrier Family 29, Member 3 in a Chinese Patient with H Syndrome显示文摘 | Jia-Wei Liu Nuo Si Lian-Qing Wang Ti Shen Xue-Jun Zeng Xue Zhang Dong-Lai Ma | 2015 | Chinese Medical Journal2015，，10： | 1 |
| 20 | A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection显示文摘 | Pollin TI Damcott CM Shen H | 2008 | Science2008，322，5908： | 1 |
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