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3篇 您的检索式:作者名="Tiang Xuan"
    题名 作者 年代 出处 被引量
1Preoperative transcatheter arterial chemoembolization and prognosis of patients with hepatocellular carcinoma, retrospective analysis of 120 cases显示文摘Lu CD Peng SY Tiang Xuan 1999World J Surg1999,23,:1
2Preoperative transcatheter arterial chemoembolization and prognosis of patients with hepatocelluilar carcinoma:retrospective analysis of 120 cases显示文摘Lu CD Peng SY Tiang Xuan 1999World J Surg1999,23,:1
3Type 2diabetes is causally associated with depression: a Mendelian randomization analysis显示文摘Type 2diabetes (T2D)has been associated with a high prevalence of depression.We aimed to determine the causal relation by performing a Mendelian randomization (MR)study using 34T2D risk genetic variants validated in East Asians as the instrumental variable (IV).An MR analysis was performed involving 11506 participants from a large longitudinal study.The T2D genetic risk score (GRS)was built using the 34typical T2D common variants.We used T2D_GRS as the IV estimator and performed inverse-variance weighted (IVW)and Egger MR analysis.The T2D_GRS was found to be associated with depression with an OR of 1.21(95%CI:1.07- 1.37)after adjustments for age,sex,body mass index,current smoking and drinking,physical activity,education, and marital status.Using T2D GRS as the IV,we similarly found a causal relationship between genetically determined T2D and depression (OR:1.84,95%CI:1.25-2.70).Though we found no association between the combined effect of the genetic IVs for T2D and depression with Egger MR (OR:0.95,95%CI:0.42-2.14),we found an association for T2D and depression with IVW (OR:1.75,95%CI:1.31-2.46)after excluding pleiotropic SNPs. Overall,the MR analyses provide evidence inferring a potential causal relationship between T2D and depression.Liping Xuan Zhiyun Zhao Xll Jia Yanan Hou Tiange Wang Mian Li Jieli Lu Yu Xu Yuhong Chen Lu Qi Weiqing Wang Yufang Bi Min Xu 2018Frontiers of Medicine2018,12,6:0
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