|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Management of gastric cancer in Asia: resource-stratified guidelines显示文摘 | Lin Shen Yan-Shen Shan Huang-Ming Hu Timothy J Price Bhawna Sirohi Kun-Huei Yeh Yi-Hsin Yang Takeshi Sano Han-Kwang Yang Xiaotian Zhang Sook Ryun Park Masashi Fujii Yoon-Koo Kang Li-Tzong Chen | 2013 | Lancet Oncology2013，，12： | 5 |
| 2 | Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma显示文摘 | John Bridgewater Peter R. Galle Shahid A. Khan Josep M. Llovet Joong-Won Park Tushar Patel Timothy M. Pawlik Gregory J. Gores | 2014 | Journal of Hepatology2014，，6： | 3 |
| 3 | Microstructure and mechanical properties of CoCrFeMnNi high entropy alloy with ultrasonic nanocrystal surface modification process显示文摘In this study, mechanical properties improvement of equiatomic CoCrFeMnNi treated with an ultrasonic nanocrystal surface modification(UNSM) was studied. The applied UNSM treatment with static loads of 10 N, 20 N, and 60 N provided a severe plastic deformation, which produced a gradient structure. The nearsurface area exhibited a high number of dislocation densities and deformation twin interaction, leading to a surface strengthening and hardness improvement of up to 112% than the deformation-free interior region. Increment of dislocation densities and deformation twin formation on the surface also enhanced the yield and ultimate tensile strength of the UNSM-treated specimens. Furthermore, the combination of hard nanocrystallites layer on the surface and ductile coarse grain in the specimen interior as a result of the UNSM treatment successfully maintained the strength–ductility balance of the CoCrFeMnNi. | Timothy Alexander Listyawan Hyunjong Lee Nokeun Park Unhae Lee | 2020 | Journal of Materials Science & Technology2020，54，22： | 2 |
| 4 | DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency显示文摘 | Timothy Hoey Wan-Ching Yen Fumiko Axelrod Jesspreet Basi Lucas Donigian Scott Dylla Maureen Fitch-Bruhns Sasha Lazetic In-Kyung Park Aaron Sato Sanjeev Satyal Xinhao Wang Michael F. Clarke John Lewicki Austin Gurney | 2009 | Cell Stem Cell2009，，2： | 1 |
| 5 | Confidenceintervals for evaluating benefits estimates from dichotomouschoice contingent valuation studies显示文摘 | Timothy Park John B Loomis Michael Creel | 1991 | Land Economy1991，67，1： | 1 |
| 6 | A through-the-scope device for suturing and tissue approximation under EUS control显示文摘 | Annette Fritscher-Ravens C.Alexander Mosse Timothy N. Mills Dip Mukherjee Per-Ola Park Paul Swain | 2002 | Gastrointestinal Endoscopy2002，，： | 1 |
| 7 | Electrospinning of linear and highly branched segmented poly(urethane urea)s显示文摘 | Matthew G. McKee Taigyoo Park Serkan Unal Iskender Yilgor Timothy E. Long | 2005 | Polymer2005，，7： | 1 |
| 8 | Analysis of GP73 in patients with HCC as a function of anti-cancer treatment显示文摘 | Hie-Won Hann Mengjun Wang Julie Hafner Ronald E. Long Su Hee Kim Meejin Ahn Susan Park Mary Ann Comunale Timothy M. Block Anand Mehta | 2010 | Cancer Biomarkers2010，，6： | 1 |
| 9 | Evaluation of Unified Model Microphysics in High-resolution NWP Simulations Using Polarimetric Radar Observations显示文摘The UK Met Office Unified Model(UM) is employed by many weather forecasting agencies around the globe. This model is designed to run across spatial and time scales and known to produce skillful predictions for large-scale weather systems. However, the model has only recently begun running operationally at horizontal grid spacings of ~1.5 km [e.g.,at the UK Met Office and the Korea Meteorological Administration(KMA)]. As its microphysics scheme was originally designed and tuned for large-scale precipitation systems, we investigate the performance of UM microphysics to determine potential inherent biases or weaknesses. Two rainfall cases from the KMA forecasting system are considered in this study: a Changma(quasi-stationary) front, and Typhoon Sanba(2012). The UM output is compared to polarimetric radar observations in terms of simulated polarimetric radar variables. Results show that the UM generally underpredicts median reflectivity in stratiform rain, producing high reflectivity cores and precipitation gaps between them. This is partially due to the diagnostic rain intercept parameter formulation used in the one-moment microphysics scheme. Model drop size is generally both underand overpredicted compared to observations. UM frozen hydrometeors favor generic ice(crystals and snow) rather than graupel, which is reasonable for Changma and typhoon cases. The model performed best with the typhoon case in terms of simulated precipitation coverage. | Marcus JOHNSON Youngsun JUNG Daniel DAWSON Timothy SUPINIE Ming XUE Jongsook PARK Yong-Hee LEE | 2018 | Advances in Atmospheric Sciences2018，35，7： | 1 |
| 10 | Extrahepatic Pseudoaneurysms and Ruptures of the Hepatic Artery in Liver Transplant Recipients: Endovascular Management and a New Iatrogenic Etiology显示文摘 | Wael E. A. Saad Niloy Dasgupta Allison J. Lippert Ulku C. Turba Mark G. Davies Sean Kumer Jason C. Gardenier Saher S. Sabri Auh-Whan Park David L. Waldman Timothy Schmitt Alan H. Matsumoto John F. Angle | 2013 | CardioVascular and Interventional Radiology2013，，1： | 1 |
| 11 | Comparing models for contingent valuation surveys: statistical efficiency and the precision of benefit estimates显示文摘 | Timothy Park John Loomls | 1992 | NJARE1992，10，： | 1 |
| 12 | Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition显示文摘 | Randy K. Bledsoe Valerie G. Montana Thomas B. Stanley Chris J. Delves Christopher J. Apolito David D. McKee Thomas G. Consler Derek J. Parks Eugene L. Stewart Timothy M. Willson Millard H. Lambert John T. Moore Kenneth H. Pearce H.Eric Xu | 2002 | Cell2002，，1： | 1 |
| 13 | Betaine–Homocysteine Methyltransferase Expression in Porcine and Human Tissues and Chromosomal Localization of the Human Gene显示文摘 | Sara L.F. Sunden Murty S. Renduchintala Eric I. Park Steven D. Miklasz Timothy A. Garrow | 1997 | Archives of Biochemistry and Biophysics1997，，1： | 1 |
| 14 | Improving high-temperature oxidation behavior by modifying Al and Co content in Al-Co-Cr-Fe-Ni high-entropy alloy显示文摘Composition modification was introduced to improve the oxidation resistance by varying Al and excluding Co from the Al-Co-Cr-Fe-Ni system. Since adjusting the composition shifted the valence electron concentration(VEC) of the alloys, the dual-phase structure of the alloys is expected to be more stable. At low temperatures(T < 1273 K), the alloys formed mixed oxide products. As oxidation temperature increased,only Cr_(2)O_(3)or Al_(2)O_(3)dominated the alloy’s surface. Compared to equiatomic AlCoCrFeNi(5-Equi), nonequiatomic AlCoCrFeNi(5-B 40) and four-component AlCrFeNi(4-B 2013) had better oxidation resistance due to monocrystalline-Al_(2)O_(3)formation. Besides the role of oxide formation, maintaining BCC and B2phases within the alloys is also beneficial to supporting the stable Cr_(2)O_(3)or Al_(2)O_(3). | Timothy Alexander Listyawan Maya Putri Agus tianingrum Young Sang Na Ka Ram Lim Nokeun Park | 2022 | Journal of Materials Science & Technology2022，，34： | 0 |
| 15 | Wheat leaf rust resistance gene Lr13 is a specific Ne2 allele for hybrid necrosis显示文摘Dear Editor,Wheat leaf rust,caused by Puccinia triticina(Pt),is a destructive fungal disease of wheat globally.Host resistance(R)genes are widely studied as a means to combat disease.Lr13 is regarded as one of the most widely distributed leaf rust R genes in wheat(McIntosh et al.,1995).Researchers observed that lines carrying Lr13 consistently gave hybrid necrosis in specific crosses. | Timothy Hewitt Jianping Zhang Li Huang Narayana Upadhyaya Jianbo Li Robert Park Sami Hoxha Robert McIntosh Evans Lagudah Peng Zhang | 2021 | Molecular Plant2021，14，7： | 0 |
| 16 | Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus显示文摘The biosynthesis of host lipids and/or lipid droplets(LDs)has been studied extensively as a putative therapeutic target in diverse viral infections.However,directly targeting the LD lipolytic catabolism in virus-infected cells has not been widely investigated.Here,we show the linkage of the LD-associated lipase activation to the breakdown of LDs for the generation of free fatty acids(FFAs)at the late stage of diverse RNA viral infections,which represents a broad-spectrum antiviral target.Dysfunction of membrane transporter systems due to virus-induced cell injury results in intracellular malnutrition at the late stage of infection,thereby making the virus more dependent on the FFAs generated from LD storage for viral morphogenesis and as a source of energy.The replication of SARS-CoV-2 and influenza A virus(IAV),which is suppressed by the treatment with LD-associated lipases inhibitors,is rescued by supplementation with FFAs.The administration of lipase inhibitors,either individually or in a combination with virus-targeting drugs,protects mice from lethal IAV infection and mitigates severe lung lesions in SARS-CoV-2-infected hamsters.Moreover,the lipase inhibitors significantly reduce proinflammatory cytokine levels in the lungs of SARS-CoV-2-and IAV-challenged animals,a cause of a cytokine storm important for the critical infection or mortality of COVID-19 and IAV patients.In conclusion,the results reveal that lipase-mediated intracellular LD lipolysis is commonly exploited to facilitate RNA virus replication and furthermore suggest that pharmacological inhibitors of LD-associated lipases could be used to curb current COVID-19-and future pandemic outbreaks of potentially troublesome RNA virus infection in humans. | Yeong-Bin Baek Hyung-Jun Kwon Muhammad Sharif Jeongah Lim In-Chul Lee Young Bae Ryu Jae-In Lee Ji-Sun Kim Young-Seung Lee Dong-Hoon Kim Sang-Ik Park Don-Kyu Kim Jeong-Sun Kim Hyon EChoy Sunwoo Lee Hueng-Sik Choi Timothy FOsborne Tae-Il Jeon Kyoung-Oh Cho | 2022 | Signal Transduction and Targeted Therapy2022，7，11： | 0 |
| 17 | A new guide for improving mechanical properties of non-equiatomic FeCoCrMnNi medium-and high-entropy alloys with ultrasonic nanocrystal surface modification process显示文摘Ultrasonic nanocrystal surface modification (UNSM) treatment on non-equiatomic medium-and highentropy alloy (HEA) of Fex(CoCrMnNi)100-xis firstly introduced and its impact on microstructure and mechanical properties are revealed.By UNSM,severe plastic deformation-induced dislocation and deformation twins (DTs) arise at the topmost surface.Especially,Fe60(CoCrMnNi)40(Fe60),which is classified as a medium-entropy alloy (MEA),exhibits ε-martensitic transformation.In the room temperature tensile test,a high strength of ~600 MPa and ductility of ~65%elongation (strain to failure) is accomplished in Fe60.Initially formed DTs and ε-martensitic transformation by UNSM treatment plays a key role in retardation of necking point via both twinning-induced plasticity and transformation-induced plasticity.However,Fe20(CoCrMnNi)80(Fe20) comparatively shows low strength of ~550 MPa and ~40% elongation,owing to the low accommodation of DTs than Fe60.Our research will provide new guidelines for enhancing the mechanical properties of MEA and HEA. | Timothy Alexander Listyawan Hyunjong Lee Nokeun Park | 2020 | Journal of Materials Science & Technology2020，59，24： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员