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55篇 您的检索式:作者名="Tirado P"
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1Specific and cross-reactive immune response against Mycobacterium tuberculosis antigens in mice immunized with proteoliposomes from Mycobacterium bovis BCG显示文摘Objective: To characterize the immunogenicity and the induction of cross-reactive responses against Mycobacterium tuberculosis(M. tuberculosis) of a proteoliposome(PL)from Mycobacterium bovis Bacillus Calmette–Guerin(BCG) with and without alum hydroxide(AL) as adjuvant(PLBCG-AL and PLBCG, respectively) in BALB/c mice.Methods: BALB/c mice were inoculated with phosphate buffer solution, BCG, PLBCG and PLBCG-AL. The humoral immunogenicity was determined by ELISA [immunoglobulin G(Ig G), Ig G1 and Ig G2a] and the cellular immunogenicity was evaluated in vivo by delayed type hypersensitivity. The humoral cross-reactive response against M. tuberculosis was determined by Western blot.Results: Sera from animals immunized with PLBCG-AL and PLBCG showed significant increase in specific total Ig G and Ig G1 antibodies and the presence of cross-reactive antibodies against M. tuberculosis antigens, which were more intense with the use of alum as adjuvant. Mice immunized with PLBCG and PLBCG-AL also showed a specific cellular response in vivo.Conclusions: The cellular and humoral immunogenicity of PLBCG and the capacity to induce cross-reactive responses against M. tuberculosis is in agreement with the protective capacity previously demonstrated by this vaccine candidate and supports the continuation of its evaluation in further stages.Nadine Alvarez DaymíSerpa Ramlah Kadir Yanely Tirado Reinier Borrero Sonsire Fernández Rubén Cabrera Yolanda Valdes Caridad Zayas Reinaldo Acevedo Luis Izquierdo María Elena Sarmiento Mohd-Nor Norazmi JoséLuis Pérez Armando Acosta 2017Asian Pacific Journal of Tropical Biomedicine2017,7,3:3
2Garcia-Hernandes显示文摘Hamilton P B Tirado F J 1990Poultry Science1990,69,:1
3Cerebrovascular accidents and atrial fibrillation in the elderly paient显示文摘Alcalde Tirado P Ribera Casado JM 1995An Med Intensa1995,12,8:1
4Cation distribution and chemical deintercalation of Li1-x Ni1+x O2显示文摘Morales J Pérez-Vicente C Tirado J L 1990Mat Res Bull1990,25,:1
5Tin oxalate as a precursor of tin dioxide and electrode materials for lithium-ion batteries显示文摘R. Alcántara Fernández F. Madrigal P. Lavela C. Pérez-Vicente J. Tirado 2001Journal of Solid State Electrochemistry2001,,1:1
6The origin of capacity fading in NiFe2O4 conversion electrodes for lithium ion bat- teries unfolded by ^57 Fe Mossbauer spectroscopy显示文摘Vidal-Abarca C Lavela P Tirado J L 2010The Journal of Physical Chemistry C2010,114,12:1
7Structure and electrochemical properties of boron-doped LiCoO2显示文摘ALACNTARA R LAVELA P TIRADO J L 1997Journal of Solid State Chemistry1997,134,:1
8Bielustering of gene expression data by Non-smooth Non negative Matrix Faetorication 显示文摘CARMONA-SAEZ P PASCUAI_MARQUI R D TIRADO F 2006BMC IAioinformatics2006,7,:1
9CoFe2O4 and NiFe2O4 Synthesized by Sol-gel Procedures for Their Use as Anode Materials for Li ion Batteries 显示文摘Lavela P Tirado J L 2007Journal of Power Sources2007,172,:1
10Sol-gel preparation of cobalt manganese mixed oxides for their use as electrode materials in lith- ium cells 显示文摘Lavela P Tirado J L Vidal-Abarca C 2007Electrochim Acta2007,52,28:1
11Biclustering of Gene Expression Data by Non-smooth Nonnegative Matrix Factorization 显示文摘Carmona-Saez P Pascual-Marqui R D Tirado F 2006BMC Bioinformatics2006,7,2:1
12Electrochemical evalu-ation of CuFe2O4 samples obtained by sol-gel methods used as anodes in lithium batteries显示文摘Bomio M Lavela P Tirado J L 2008J Solid State Electrochem2008,12,:1
13Cation distribution and chemi- cal deintercalation of Lil- ,Nil + xO2显示文摘Morales J Vicente C P Tirado J L 1990Mater Res Bull1990,25,5:1
14CoFe2O4 and NiFe2O4 synthesized by sol-gel procedures for their use as anode materials for Li ion batteries显示文摘LAVELA P TIRADO J L 2007Journal of Power Sources2007,172,:1
15CoFe2O4 and NiFe2O4 synthesized by sol-gel procedures for their use as anode materials for Li ion batteries显示文摘Lavela P Tirado J L 2007Journal of Power Sources2007,172,:1
16Structure and electrochemical properties of boron-doped LiCoO2显示文摘Alcantara R Lavela P Tirado J L 1997J Solid State Chemistry1997,134,2:1
17Sol-gel preparation of cobalt manganese mixed oxides for their use as electrode materials in lithium cells 显示文摘LAVELA P TIRADO J L VIDAL-ABARCA C 2007Electrochimica Acta2007,52,28:1
18Transcervical intrapartum amnioinfusion for preterm premature rupture of the membr-anes显示文摘Puertas A Tirado P Pérez I 2007Eur J Obstet Gynecol Reprod Biol2007,131,1:1
19Transcervical intrapartum am- nioinfusion for preterm premature rupture of the membranes显示文摘Puertas A Tirado P P6rez I et a/ 2007Nut J Obstet Gynecol Reprod Biol2007,31,1:1
20Transcervical intrapartum amnioinfu- sion for preterm premature rupture of the membranes显示文摘Puertas A Tirado P P6rez I 2007Eur J Obstet Gynecol Reprod Biol2007,131,1:1
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