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| 1 | Zebrafish as a model for developmental neurotoxicity testing 显示文摘 | Ton C Lin Y Willett C | 2006 | Birth Defects Res A Clin Mol Teratol2006，76，7： | 1 |
| 2 | Zebrafish as a model for developmental neurotoxicity testing 显示文摘 | TON C LIN Y X WILLETT C | 2006 | Birth Defects Res A Clin Mol Teratol2006，76，7： | 1 |
| 3 | Irrigation scheduling of avocado using phytomonitoring techniques 显示文摘 | Gurovich L A Ton Y Vergara L M | 2006 | Cieneiae Investigacion Agraria2006，33，2： | 1 |
| 4 | Blood glucose measurements by photoacoustcs显示文摘 | Mackenzie H A Ash ton H S Shen Y C | 1998 | Trends Photonies1998，22，： | 1 |
| 5 | Neurotoxicity assessment using zebrafish显示文摘 | Parng C Roy NM Ton C Lin Y Mc Grath P | 2007 | J Pharmacol Toxicol Methods2007，55，1： | 1 |
| 6 | Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet-induced obese rats 显示文摘 | Eu C H Lim W Y Ton S H | 2010 | Lipids Health Dis2010，29，9： | 1 |
| 7 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 8 | Zebrafish as a model for developmental neurotoxicity testing显示文摘 | TON C LIN Y WILLETT C | 2006 | Birth Defects Res A Clin Mol Teratol2006，76，7： | 1 |
| 9 | Secure spread:an integrated architecture for secure group communication显示文摘 | AMIR Y NITA-ROTARU C STAN TON J | 2005 | IEEE Trans on Dependable and Secure Computing2005，2，3： | 1 |
| 10 | Mutational dynamics of the SARS coronavirus in cell culture and human populations iso- lated in 2003 显示文摘 | Vega VB Ruan Y Liu J Lee WH Wei CL Se-Thoe SY Tang KF Zhang T Kolatkar PR Ooi EE Ling AIE Stan- ton LW Long PM Liu ET | 2004 | BMC Infect Dis2004，4，： | 1 |
| 11 | Effect of stachydrine on endoplasmic reticulum stress - induced apoptosis in rat kidney af- ter unilateral ureteral obstruction 显示文摘 | ZHANG C LU Y TON Q Q G | 2013 | Journal of Asian natural products research2013，15，4： | 1 |
| 12 | Zebrafish as a model for develop-mental neurotoxicity testing显示文摘 | TON C LIN Y WILLETT C | 2006 | Birth Defects Res A Clin Mol Te-ratol2006，76，7： | 1 |
| 13 | Zebrafish as a model for developmental neurotoxicity testing 显示文摘 | TON C LIN Y WILLErI: C | 2006 | Birth Defects Res A Clin Mol Teratol2006，76，7： | 1 |
| 14 | A hypothesis on the mechanism of trauma of lung tissue subjected to impact load显示文摘 | Fung Y C Yen R T Ton Z J et at | 1988 | J Biomech Eng1988，110，1： | 1 |
| 15 | Refractive error in premature infants显示文摘 | Ton Y Wysenbeek YS Spierer A | | 0，，6： | 1 |
| 16 | Zebrafish as a model for developmentalneurotoxicity testing显示文摘 | Ton C Lin Y Willett C | 2006 | Birth Defects Res A Clin Mol Teratol2006，76，7： | 1 |
| 17 | Secure spread:an integrated architecture for secure group communication 显示文摘 | AMIR Y NITA-ROTARU C STAN TON J | 2005 | IEEE Trans on Dependable and Secure Computing2005，2，3： | 1 |
| 18 | Pulmonary hypertensionin patients with chronic obstructive pulmonary disease:recentadvances in pathophysiology and management显示文摘 | Hida W Ton Y Kikuchi Y | 2002 | Respirology2002，7，1： | 1 |
| 19 | Evaluation of acute toxicity and teratogenic effects of disinfectants by Daphnia magna embryo assay显示文摘 | TON S S CHANG S H HSU L Y | 2012 | Environmental Pollution2012，168，： | 1 |
| 20 | Phytomonitoring: A bridge from sensors to informationtechnology forgreenhouso control显示文摘 | Ton Y Kopyt M | 2003 | ActaHort2003，614，： | 1 |
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