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| 1 | Dimethoate Induced Oxidative Damage and Histopathological Changes in lung of Adult rats:Modulatory Effects of Selenium and/or Vitamin E显示文摘Objective To determine the efficiency of selenium and/or vitamin E to alleviate lung oxidative damage induced by dimethoate,an organophosphorus compound.Methods Adult Wistar rats were exposed during 30 days either to dimethoate (0.2 g/L of drinking water),dimethoate+selenium (0.5 mg/kg of diet),dimethoate+vitamin E (100 mg/kg of diet),or dimethoate+selenium+vitamin E.Results Exposure to dimethoate caused oxidative stress in lung evidenced by an increase of malondialdehyde,protein carbonyl groups and advanced oxidation protein products.An increase in glutathione peroxidase,superoxide dismutase,catalase and a decrease in acetylcholinesterase and butyrylcholinesterase activities,glutathione,non-protein thiols and vitamins C levels were observed.Histopathological changes in lung tissue were noted as emphysema,hemorrhages and hemosiderin deposits.Co-administration of selenium or vitamin E to the diet of dimethoate treated rats ameliorated the biochemical parameters as well as histological impairments.The joint effect of these elements was more powerful in antagonizing dimethoate-induced lung oxidative damage.Conclusion We concluded that selenium and vitamin E ameliorated the toxic effects of this pesticide in lung tissue suggesting their role as potential antioxidants. | Ibtissem Ben AMARA Nejla SOUDANI Afef TROUDI Ahmed HAKIM Khaled Mounir ZEGHAL Tahia BOUDAWARA Najiba ZEGHAL | 2012 | Biomedical and Environmental Sciences2012，25，3： | 2 |
| 2 | HLA class II polymorphism: protective or risk factors to breast cancer in Tunisia显示文摘 | Baccar HA Yacoubi Loueslati B Troudi W et a1 | 2006 | Pathol Oncol Res2006，12，2： | 1 |
| 3 | Protective effects of selenium on methimazole nephrotoxicity in adult rats and their offspring显示文摘 | Ibtissem Ben Amara Afef Troudi Elmouldi Garoui Ahmed Hakim Tahia Boudawara Khaled Mounir Zeghal Najiba Zeghal | 2010 | Experimental and Toxicologic Pathology2010，，6： | 1 |
| 4 | Hepatotoxicity induced by gibberellic acid in adult rats and their progeny 显示文摘 | Troudi A Samet AM Zeghal N | 2009 | Experimental and Toxicologic Pathology2009，48，2： | 1 |
| 5 | Protective effects of selenium on methimazole nephrotoxicity in adult rats andtheir offspring显示文摘 | Ben Amara I Troudi A Garoui E | 2011 | Experimental and Toxicologic Pathology2011，63，6： | 1 |
| 6 | Protective effects of selenium on methimazole nephrotoxicity in adult rats and their offspring显示文摘 | Ben Amara I Troudi A Garoui E | 2011 | Exp Toxicol Pathol2011，63，6： | 1 |
| 7 | Ameliorating effect of selenium on chromium (VI)-induced oxidative damage in the brain of adult rats显示文摘 | Soudani N Troudi A Amara IB | 2012 | J Physiol Biochem2012，68，3： | 1 |
| 8 | Mary and her teachers: A Brego-speaking child's place in the mainstream classroom显示文摘 | Platt E & Troudi S | 1997 | The Modem Language Journal1997，，81： | 1 |
| 9 | Poly- morphism of the mitochondrial microsatellite 303 -315 in breast cancer in Tunisia 显示文摘 | Yacoubi-Loueslati B Troudi W Baccar A | 2009 | Bull Cancer2009，96，： | 1 |
| 10 | Immunolocalization of BRCA1 protein in tumor breast tissue: prescreening of BRCA1 mutation in Tunisian patients with hereditary breast cancer 显示文摘 | Troudi W Uhrhammer N Ben Romdhane K | 2007 | Eur J Histochem2007，51，3： | 1 |
| 11 | Hepatotoxicity induced by gibberellic acid in adult rats and their progeny显示文摘 | TROUDI A SAMET A M ZEGHAL N | 2010 | Experimental and Toxicologic Pathology2010，62，6： | 1 |
| 12 | lmpact of defect on l(V)instabilities observed on Ti/4H SiC high voltage Schottky diodes显示文摘 | Abdelwahed N Troudi M Sghaier N | 2015 | Microelectronics Reliability2015，55，8： | 1 |
| 13 | Neurotoxicity and oxidative stress induced by gibberellic acid in rats during late pregnancy and early postnatal periods: biochemical and histological changes显示文摘 | TROUDI A BOUAZIZ H SOUDANI N | 2012 | Experimental and Toxicologic Pathology2012，64，6： | 1 |
| 14 | Oxidative stress in- duced by gibberellic acid in bone of suckling rats 显示文摘 | Troudi A Ben Amara I Soudani N | 2011 | Ecotoxicology and Environmental Safety2011，74，： | 1 |
| 15 | Hepatotoxicity in- duced by gibberellic acid in adult rats and their progeny 显示文摘 | Troudi A Mahjoubi Samet A Zeghal N | 2010 | Experimental and Toxicologic Pathology2010，62，： | 1 |
| 16 | Polyphased Dolomitization of aShoal rimmed Carbonate Platform; Example from the Middle Turonian Bireno Dolomites of Central Tunisia显示文摘 | Touir J Soussi M Troudi H | 2009 | Cretaceous Research2009，30，3： | 1 |
| 17 | Oxidative damage in bone and erythrocytes of suckling rats exposed to 2, 4-dichlorophenoxyacetic acid 显示文摘 | Troudi A Soudani N Amara I B | 2012 | Pestic Biochem Physiol2012，104，1： | 1 |
| 18 | Polymorphism of the mitochondrial microsatellite 303-315 in breast cancer in Tunisia显示文摘 | Yacoubi Loueslati B Troudi W Baccar A | | 0，，03： | 1 |
| 19 | 2, 4-dichlorophenoxyacetic acid effects on nephrotoxicity in rats during late pregnancy and early postnatal periods显示文摘 | Troudi A Soudani N Mahjoubi Samet A | 2011 | Ecotoxicol Environ Saf2011，74，8： | 1 |
| 20 | Oxidative stress induced by 2, 4-phenoxyacetic acid in liver of female rats and their progeny:biochemical and histopathological studies显示文摘 | Troudi A Ben Amara I Samet AM | 2012 | Environ Toxicol2012，27，3： | 1 |
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