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| 1 | Impact of body composition on survival and morbidity after liver resection in hepatocellular carcinoma patients显示文摘Background: Hepatocellular carcinoma is the most common innate liver tumor. Due to improved surgical techniques, even extended resections are feasible, and more patients can be treated with curative intent. As the liver is the central metabolic organ, preoperative metabolic assessment is crucial for risk stratification. Sarcopenia, obesity and sarcopenic obesity characterize body composition and metabolic status. Here we present the impact of body composition on survival after liver resection in patients with hepatocellular carcinoma. Methods: A retrospective database analysis of 70 patients who were assigned for liver resection due to hepatocellular carcinoma was conducted. For assessment of sarcopenia and obesity, skeletal muscle surface area was measured at lumbar vertebra 3 level(L3) in preoperative four-phase contrast enhanced abdominal CT scans, and L3 muscle index and body fat percentage were calculated. Results: Univariate analysis comparing the survival curves using the score test demonstrated superior postoperative overall survival for sarcopenic( P = 0.035) and sarcopenic obese( P = 0.048) patients as well as a trend favoring obese( P = 0.130) subjects. Whereas multivariate analysis could not identify significant difference in postoperative survival regarding sarcopenia, obesity or sarcopenic obesity. Only large tumor size, multifocal disease and male gender were risk factors for long-term survival. Conclusions: Sarcopenia, obesity and sarcopenic obesity are indeed no risk factors for poor postoperative survival in this study. Our data do not support the evaluation of sarcopenia, obesity and sarcopenic obesity before liver resection in hepatocellular carcinoma patients. | Andreas Kroh Diane Uschner Toine Lodewick Roman M Eickhoff Wenzel Sch?ning Florian T Ulmer Ulf P Neumann Marcel Binneb?sel | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 5 |
| 2 | FISH analysis in chromophobe renal cell carcinoma显示文摘 | IQBAL M A AKHTAR M ULMER C | 2000 | Diagn Cytopathol2000，22，1： | 1 |
| 3 | Association,commissural,and projection pathways and their functional deficit reported in the literature显示文摘 | Aralasmak A Ulmer JL Kocak M | | 0，，05： | 1 |
| 4 | Endosonography of upper gastrointestinal tract cancer on demand using miniprobes or endoscopic ultrasound 显示文摘 | Hunerbein M Ulmer C Handke J | 2003 | Surg Endosc2003，17，4： | 1 |
| 5 | Testing individual risk of acute mountain sickness at greater altitudes 显示文摘 | TANNHEIMER M ALBERTINI N ULMER H V | 2009 | Mil Med2009，174，4： | 1 |
| 6 | Association,com-missural,and projection pathways and their functional deficit reported in the literature显示文摘 | Andasmak A Ulmer JL Kocak M | 2006 | J Comput Assist Tomogr2006，30，5： | 1 |
| 7 | Freeway traffic flow rate measurement: investigation into impact of measure- ment time interval 显示文摘 | Smith B L Ulmer J M | 2003 | Journal of Transportation En- gineering2003，129，3： | 1 |
| 8 | Myocardial bridging of the anterior interventricular coronary artery in setting of hyper- trophic cardiomyopathy in children and adolescent 显示文摘 | Sebening C Gorenflo M Ulmer HE | 2002 | Cardiol Young2002，12，： | 1 |
| 9 | Effects of Pulsed Electric Fields on Inactivation and Metabolic Activity of Lactobacillus Plantarum in Model Beer显示文摘 | ULMER H M HEINZ V GANZLE M G | 2002 | J Appl Microbiol2002，93，3： | 1 |
| 10 | The novel apolipoprotein A5 is present in human serum,is associated with VLDL,HDL,and chylomicrons,and circulates at very low concentrations compared with other apolipoproteins显示文摘 | O'Brien PJ Alborn WE Sloan JH Ulmer M Boodhoo A Knieman MD | 2005 | Clin Chem2005，51，2： | 1 |
| 11 | MRI graduation of osseous reaction and drill hole consolidation after arthroscopic Bankart repair with PLLA anchors and the clinical relevance显示文摘 | Stein T Mehling AP Ulmer M | 2012 | Knee Surg Sports Traumatol Arthrosc2012，20，11： | 1 |
| 12 | DNA vaccine显示文摘 | Donnelly J J Ulmer J B Liu M A | 1997 | Life Sci1997，60，： | 1 |
| 13 | Human clinical trials of plasmid DNA vaccines显示文摘 | LIU M A ULMER J B | 2005 | Adv Genet2005，55，： | 1 |
| 14 | A set of SAS macros for calculating and displaying adjusted odds ratios(with confidence intervals) for continuous covariates in logistic B-spline regression models显示文摘 | Gregory M Ulmer H Pfeiffer KP | 2008 | Comput Methods Programs Biomed2008，92，： | 1 |
| 15 | Testing individual risk of acute mountain sickness at greater altitudes 显示文摘 | Tannheimer M Albertini N Ulmer HV | 2009 | Mil Med2009，174，4： | 1 |
| 16 | Selenium supplementation restores the antioxidative capacity and prevents cell damage in bone marrow stroms! cells in vitro显示文摘 | Ebert R Ulmer M Zeck S et s! | 2006 | Stem Cells2006，24，5： | 1 |
| 17 | FISH analysis in chromophobe renal-cell carcinoma 显示文摘 | Iqbal MA Akhtar M Ulmer C | 2000 | Diagn Cytopathol2000，22，1： | 1 |
| 18 | Antigen presenta- tion and DNA vaccines 显示文摘 | DONNELLY J J LIU M A ULMER J B | 2000 | American Journal of Respiratory and Critical Care Medicine2000，162，42： | 1 |
| 19 | In vivo investigation of the efficien- cy of a nanoparticle-emulsion containing polihexanide on the human skin显示文摘 | Ulmer M Patzeh A Vergou T | 2013 | Eur J Pharm Biopharm2013，84，2： | 1 |
| 20 | Expression of a viral protein by muscle cells in vivo induces protective cell -mediated immunity 显示文摘 | ULMER J B DECK R R DEWITY C M | 1997 | Vaccine1997，15，8： | 1 |
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