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| 1 | Lymphomatoidgastropathy mimicking extranodal NK/T cell lymphoma,nasal type:A case report显示文摘Extranodal natural killer(NK)/T-cell lymphoma,nasal type,exhibits aggressive tumor behavior and carries a poor prognosis.Recently,lymphomatoid gastropathy with NK/T cell infiltration into gastric mucosa has been recognized as a pseudo-malignant disease which regresses without treatment.Because the conventional immunohistochemical criteria of lymphomatoid gastropathy is similar to that of extranodal NK/T-cell lymphoma nasal type,it is difficult to distinguish between the two conditions by histopathological evaluation only.Here,we report a rare case of lymphomatoid gastropathy in a 57-year-old female.Gastroendoscopy on routine check-up revealed elevated reddish lesions < 1 cm in diameter in the gastric fornix and body.Although repeat endoscopies at 1 and 6 mo later revealed no gastric lesions at any locations without any treatments,at 12 mo later gastric lymphomatoid lesions recurred at gastric fornix and body.Histological examination of endoscopic biopsy specimens at 12 mo showed atypical NK cell infiltration with CD3+,CD4-,CD5-,CD7+,CD8-,CD20-,CD30-,CD56+,CD79a-and T-cell-restricted intracellular antigen-1+ into gastric mucosa.After treatment for Helicobacter pylori(H.pylori) eradication,the lesions disappeared in all locations of the gastric fornix and body over the subsequent 12 mo.Here,we report a case of H.pylori-positive lymphomatoid gastropathy with massive NK-cell proliferation,and also review the literature concerning newly identified lymphomatoid gastropathy based on comparison of extra nodal NK/T-cell lymphoma nasal type.In any case,these lesions are evaluated with biopsy specimens,the possibility of this benign entity should be considered,and excessive treatment should be carefully avoided.Close follow-up for this case of lymphomatoid gastropathy is necessary to exclude any underlying malignancy. | Tomohiro Terai Mitsushige Sugimoto Hiroki Uozaki Tetsushi Kitagawa Mana Kinoshita Satoshi Baba Takanori Yamada Satoshi Osawa Ken Sugimoto | 2012 | World Journal of Gastroenterology2012，18，17： | 5 |
| 2 | Detection of minimal gastric cancer cells in peritoneal washings by focused microarray analysis with multiple markers 显示文摘 | Mori K Suzuki T Uozaki H | 2007 | Ann Surg Oncol2007，14，5： | 1 |
| 3 | Epstein-Barr virus and gastric carcinoma: virus-host interactions leading to carcinoma 显示文摘 | Fukayama M Hino R Uozaki H | 2008 | Cancer Sci2008，99，9： | 1 |
| 4 | Overexpression of resistance- related proteins ( metallothionein, glutathiones- transferases, heat shock protein 27, and lung resistance-related protein ) in osteosarcoma 显示文摘 | Uozaki H Horiuchi H Ishida T | 1997 | Cancer1997，79，12： | 1 |
| 5 | The Critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages 显示文摘 | Igarashi M Osuga J Uozaki H | 2010 | Circ Res2010，107，11： | 1 |
| 6 | Expression of heat shock proteins in osteosarcoma and its relationship to prognosis显示文摘 | Uozaki H Ishida T Kakiuchi C | 2000 | Pathol Res Pract2000，196，10： | 1 |
| 7 | Signet ring cell carcinoma of the appendix manifesting as colonic obstruction and ovarian tumors: Report of a case显示文摘 | Jun Suzuki Shinsuke Kazama Joji Kitayama Hiroshi Uozaki Tetsuro Miyata Hirokazu Nagawa | 2009 | Surgery Today2009，，3： | 1 |
| 8 | Cyclooxygenase-2 regulates the degree of apoptosis by modulating bcl-2 protein in pleomorphic adenoma and mucoepidermoid carcinoma of the parotid gland显示文摘 | Sakamoto T Uozaki H Kondo K | 2005 | Acta Otolaryngol2005，125，2： | 1 |
| 9 | Phenotype analysis by MUC2, MUCSAC, MUC6, and CD10 expression in Epstein-Barr virus-associated gastric carcinoma显示文摘 | Barua RR Uozaki H Chong JM | 2006 | J Gastroenterol2006，41，8： | 1 |
| 10 | Expression of heat shock proteins in osteosarcoma and its relationship to prognosis显示文摘 | UOZAKI H ISHIDA T KAKIUCHI C | 2000 | Path Res Pract2000，196，： | 1 |
| 11 | Inhibition of multiplication of herpes simplex virus by caffeic acid显示文摘 | Ikeda K Tsujimoto K Uozaki M | 2011 | Int J Mol Med2011，28，4： | 1 |
| 12 | Overexpression of resistance-related proteins(metallothionein,glutathione-s-transferaseπ,heat shock protein 27,and lung resistanc-related protein)inosteosarcoma显示文摘 | Horiuchi H Ishida T | 1997 | Cancer1997，79，12： | 1 |
| 13 | Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric carcinoma显示文摘 | Hino R Uozaki H Murakami N | 2009 | Cancer Res2009，69，7： | 1 |
| 14 | Epstein-Barr virus and gastric carcinoma:virus-host interactions leading to carcinoma显示文摘 | Fukayama M Hino R Uozaki H | | 0，，09： | 1 |
| 15 | Epstein-Barr virus and gastric carcinoma: virus-host interactions leading to carci?noma显示文摘 | FUKAYAMA M HINO R UOZAKI H | 2008 | Cancer Sci2008，99，9： | 1 |
| 16 | Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric显示文摘 | Hino R Uozaki H Murakami N | | 0，，07： | 1 |
| 17 | Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric careinoma显示文摘 | Hino R Uozaki H Murakami N | 2009 | Cancer Res2009，69，7： | 1 |
| 18 | p73 gene promoter methylation in Epstein-Barr virus-associated gastric carcinoma显示文摘 | Ushiku T Chong JM Uozaki H | 2007 | Int J Cancer2007，120，1： | 1 |
| 19 | Overexpression of resistance-related proteins (metallothionein, glutathione-s-transferase π, heat shock protein 27, and lung resistance -related protein)in osteosarcoma显示文摘 | Uozaki H Horiuchi H Ishida T | 1997 | Cancer1997，79，12： | 1 |
| 20 | Survival advantage of EBV-associated gastric carcinoma:survivin up-regulation by viral latent membrane protein 2A显示文摘 | Hino R Uozaki H Inoue Y | | 0，，05： | 1 |
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