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| 1 | Preparation and characterization of nanoparticles from quaternized cyclodextrin-grafted chitosan associated with hyaluronic acid for cosmetics显示文摘Hyaluronic acid(HA, 20–50 kDa) is a hydrophilic macromolecule with anti-wrinkle effects and moisturizing properties. However, its high molecular weight prevents it from penetrating into the deeper layers of the skin and, thus, limits its benefits to topical effects. Thus, the objective of this study is to prepare nanoparticles of quaternized cyclodextrin-grafted chitosan(QCD-g-CS) associated with HA in different molar ratios of QCD-g-CS and HA. The conjugation of the carboxylic moieties of HA and the amides of QCD-g-CS was confirmed by Fourier-transform infrared spectroscopy. Thus, the system was optimized to create nanoparticles with a small size(235.63 ± 21.89 nm), narrow polydispersity index(0.13 ± 0.02), and zeta potential of 16.07 ± 0.65 m V. The association efficiency and loading efficiency were determined by ultra-performance liquid chromatography as 86.77 ± 0.69% and 10.85 ± 0.09%, respectively. The spherical morphology of the obtained nanoparticles was confirmed by transmission electron microscopy. Moreover, the in-vitro hydrating ability was significantly higher( P < 0.001) than that of bulk HA(3.29 ± 0.41 and 1.71 ± 0.05 g water/g sample, respectively). The safety of these nanoparticles at concentrations in the range of 0.01–0.10 mg/ml was confirmed via tests on human skin fibroblasts. Together, these results demonstrate that the developed nanoparticles are promising for future applications in cosmetics. | Sakhiran Sakulwech Nattaya Lourith Uracha Ruktanonchai Mayuree Kanlayavattanakul | 2018 | Asian Journal of Pharmaceutical Sciences2018，13，5： | 3 |
| 2 | Mucoadhesive property and biocompatibility of methylated N -aryl chitosan derivatives显示文摘 | Warayuth Sajomsang Uracha Rungsardthong Ruktanonchai Pattarapond Gonil Onanong Nuchuchua | 2009 | Carbohydrate Polymers2009，，4： | 1 |
| 3 | Drug-loaded electrospun mats of poly ( vinyl alcohol ) fibers and their release characteristics of four model drugs显示文摘 | Pattama T Uracha R Pitt S | 2006 | Nanotechnology2006，17，9： | 1 |
| 4 | Incorporation methods for cholic acid chitosan-g-mPEG self-assembly micellar system containing camptothecin显示文摘 | Tanasait Ngawhirunpat Nanthida Wonglertnirant Praneet Opanasopit Uracha Ruktanonchai Rangrong Yoksan Kaewkarn Wasanasuk Suwabun Chirachanchai | 2009 | Colloids and Surfaces B: Biointerfaces2009，，1： | 1 |
| 5 | Review:Development of SARS-CoV-2 immuno-enhanced COVID-19 vaccines with nano-platform显示文摘Vaccination is the most effective way to prevent coronavirus disease 2019(COVID-19).Vaccine development approaches consist of viral vector vaccines,DNA vaccine,RNA vaccine,live attenuated virus,and recombinant proteins,which elicit a specific immune response.The use of nanoparticles displaying antigen is one of the alternative approaches to conventional vaccines.This is due to the fact that nano-based vaccines are stable,able to target,form images,and offer an opportunity to enhance the immune responses.The diameters of ultrafine nanoparticles are in the range of 1–100 nm.The application of nanotechnology on vaccine design provides precise fabrication of nanomaterials with desirable properties and ability to eliminate undesirable features.To be successful,nanomaterials must be uptaken into the cell,especially into the target and able to modulate cellular functions at the subcellular levels.The advantages of nano-based vaccines are the ability to protect a cargo such as RNA,DNA,protein,or synthesis substance and have enhanced stability in a broad range of pH,ambient temperatures,and humidity for long-term storage.Moreover,nano-based vaccines can be engineered to overcome biological barriers such as nonspecific distribution in order to elicit functions in antigen presenting cells.In this review,we will summarize on the developing COVID-19 vaccine strategies and how the nanotechnology can enhance antigen presentation and strong immunogenicity using advanced technology in nanocarrier to deliver antigens.The discussion about their safe,effective,and affordable vaccines to immunize against COVID-19 will be highlighted. | Nawamin Sa-nguanmoo Katawut Namdee Mattaka Khongkow Uracha Ruktanonchai YongXiang Zhao Xing-Jie Liang | 2022 | Nano Research2022，15，3： | 1 |
| 6 | Morphological characterization of encapsulated fish oil with b-cyclodextrin and polycaprolactone 显示文摘 | Mi-Jung Choi Uracha Ruktanonchai Apinan Soottitantawat | 2009 | Food Research International2009，42，： | 1 |
| 7 | In vitro biological evaluation of electrospun cellulose acetate fiber mats containing asiaticoside or curcumin显示文摘 | Orawan Suwantong Uracha Ruktanonchai Pitt Supaphol | | 0，，04： | 1 |
| 8 | Electrospun cellulose acetate fiber mats containing asiaticoside or Centella asiatica crude extract and the release characteristics of asiaticoside显示文摘 | Orawan Suwantong Uracha Ruktanonchai Pitt Supaphol | | 0，，19： | 1 |
| 9 | Physical characteristics of fish oil encapsulated by β- cyclodextrin using an aggregation method or polycapro- lactone using an emulsion diffusion method 显示文摘 | Mi-Jung Choi Uracha Ruktanonchai Sang-Gi Min | 2009 | Food Chemistry2009，，18： | 1 |
| 10 | Effect of surfactant on characteristics of solid lipid nanoparticles (SLN) 显示文摘 | Kullavadee KO Uracha R Smith SM | 2012 | Adv Mater Res2012，364，10： | 1 |
| 11 | Hybrid biomimetic electrospun fibrous mats derived from poly (8-capro lactone) and silk fibroin protein for wound dressing application 显示文摘 | JESADA C URACHA R PITT S | 2015 | Applied Polymer Science2015，132，11： | 1 |
| 12 | Methylated N- (4-pyridinylmethyl) chitosan as a novel effective safe gene carrier显示文摘 | Opanasopita Praneet Sajomsang Warayuth Ruktanonchai Uracha | 2008 | International Journal ofPharmaceutics2008，364，： | 1 |
| 13 | MorphologicalCharacterization of Encapsulated Fish Oil with ^Cyclo-dextrin and Polycaprolactone显示文摘 | MI-JUNG CHOIA URACHA RUKTANONCHAI APINAN SOOTTITANTAWAT el al | 2009 | Food Research Inter-nationa2009，142，： | 1 |
| 14 | Elec- trospun cellulose acetate fiber mats containing asiaticoside or Centella asiatica crude extract and the release characteristics of asiaticoside显示文摘 | Orawan Suwantong Uracha Ruktanonchai Pitt Supaphol | 2012 | Polymer2012，49，19： | 1 |
| 15 | Vi- tamin-loaded eleetrospun cellulose acetate nanofiber mats as transdermal and dermal therapeutic agents of vitamin A acid and vitamin E显示文摘 | Pattama Taepaiboon Uracha Rungsardthong Pitt Supaphol | 2007 | European Journal of Pharmaceutics and Biop- harmaceutics2007，67，2： | 1 |
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