|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Homing and migration of mesenchymal stromal cells: How to improve the efficacy of cell therapy?显示文摘Mesenchymal stromal cells(MSCs) are currently being investigated for use in a wide variety of clinical applications. For most of these applications, systemic delivery of the cells is preferred. However, this requires the homing and migration of MSCs to a target tissue. Although MSC hominghas been described, this process does not appear to be highly efficacious because only a few cells reach the target tissue and remain there after systemic administration. This has been ascribed to low expression levels of homing molecules, the loss of expression of such molecules during expansion, and the heterogeneity of MSCs in cultures and MSC culture protocols. To overcome these limitations, different methods to improve the homing capacity of MSCs have been examined. Here, we review the current understanding of MSC homing, with a particular focus on homing to bone marrow. In addition, we summarize the strategies that have been developed to improve this process. A better understanding of MSC biology, MSC migration and homing mechanisms will allow us to prepare MSCs with optimal homing capacities. The efficacy of therapeutic applications is dependent on efficient delivery of the cells and can, therefore, only benefit from better insights into the homing mechanisms. | Ann De Becker Ivan Van Riet | 2016 | World Journal of Stem Cells2016，8，3： | 37 |
| 2 | SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress显示文摘 | Hyun-Seok Kim Krish Patel Kristi Muldoon-Jacobs Kheem S. Bisht Nukhet Aykin-Burns J. Daniel Pennington Riet van der Meer Phuongmai Nguyen Jason Savage Kjerstin M. Owens Athanassios Vassilopoulos Ozkan Ozden Seong-Hoon Park Keshav K. Singh Sarki A. Abdulka | 2010 | Cancer Cell2010，，1： | 3 |
| 3 | Effect of the HDAC inhibitor vorinostat on the osteogenic differentiation of mesenchymal stem cells in vitro and bone formation in vivo显示文摘 | Song XU Kim DE VEIRMAN Holly EVANS Gaia Cecilia SANTINI: Isabelle VANDE BROEKI XavierLELEU Ann DEBECKER Ben VAN CAMP Peter CROUCHER Karin VANDERKERKEN Ivan VAN RIET | 2013 | Acta Pharmacologica Sinica2013，34，5： | 3 |
| 4 | Prognostic value of bone sialoprotein expression in clinically localized hu- man prostate cancer显示文摘 | Waltregny D Bellahcene A Van Riet I | 1998 | J Natl Cancer Inst1998，90，13： | 1 |
| 5 | Detrimental ef- fects of overstttffing or understuffing with a radial head replacement in the medial collateral-ligament deficient elbow 显示文摘 | Van Glahbeek F Van Riet RP Baumfeld JA | 2004 | J Bone Joint Surg ( Am )2004，86，12： | 1 |
| 6 | Associated injuries complicating radial head fractures : a demographic study 显示文摘 | van Riet RP Morrey BF O'Driscoll SW | 2005 | Clin Orthop2005，，35： | 1 |
| 7 | A conformationnumber to quantify the degree of conformality in brachytherapy and extemal beam irradiation:Application to the prostate 显示文摘 | Van'Riet MS Mak AC Moeland MA | 1997 | Int J Ra- diat Oncol Biol Phys1997，37，3： | 1 |
| 8 | Aconformation number to quantify the degree of conformality inbrachytherapy and external beam irradiation: application to theprostate显示文摘 | VAN'T RIET A MAK A C MOERLAND M A | 1997 | Int J Radiat Oncol Biol Phys1997，37，： | 1 |
| 9 | The incidence of associated fractures of the upper limb in fractures of the radial head 显示文摘 | Kaas L van Riet RP Vroemen JP | 2008 | Strategies Trauma Limb Reconstr2008，，3： | 1 |
| 10 | Relationship between A1C and glucose levels in the general Dutch population: the new Hoorn study 显示文摘 | van't Riet E Alssema M Rijkelijkhuizen JM | 2010 | Diabetes Care2010，33，1： | 1 |
| 11 | A conformation number to quantify the degree of eonformality in braehytherapy and external beam irradiation, Application to the prostate显示文摘 | Van't Riet A Mak AC Moerland MA | 1907 | Int J Radiat Oneol Biol Phys1907，37，3： | 1 |
| 12 | Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization显示文摘 | Lieben Liesbet Masuyama Ritsuko Torrekens Sophie Van Looveren Riet Schrooten Jan Baatsen Pieter Lafage-Proust Marie-Hélène Dresselaers Tom Feng Jian Q Bonewald Lynda F Meyer Mark B Pike J Wesley Bouillon Roger Carmeliet Geert | 2012 | EN2012，，5： | 1 |
| 13 | Sulfidation and thiophene hydrodesulfurizationactivity of nickel tungsten sulfide model catalysts, prepared without and with chelating agents 显示文摘 | KISHAN G COULIER L de BEER V H J van VEEN J A R RIET J W | 2000 | J Catul2000，196，1： | 1 |
| 14 | Delayed treatment of elbow pain and dysfunction following Essex- Lopresti injury with metallic radial head replacement: a case series显示文摘 | Heijink A Mmey BF van Riet RP | 2010 | J Shoulder Elbow Surg2010，19，6： | 1 |
| 15 | A conformation number to quantify the degree of conformity in brachytherapy and external beam irradiation:application to the prostate显示文摘 | van't Riet A Mak AC Moerland MA | 1997 | Int J Radiat Oncol Biol Phys1997，37，3： | 1 |
| 16 | Development and Testing of a Fully Automated System to Accurately Control Downhole Pressure During Drilling Operations 显示文摘 | Van Riet E J Reitsma D Vandecraen B | 2003 | SPE/IADC 853102003，，： | 1 |
| 17 | Meta-analysis of techniques for closure of midline abdominal incisions显示文摘 | Van't Riet M Steyerberg EW Nellensteyn J | 2002 | Br J Surg2002，89，1： | 1 |
| 18 | Estimation of axial dispersion in individual sections of an airlift - loop reactors 显示文摘 | Verlaan P Van Eijs A M M Vant Riet K | 1989 | Chemical Engineering Science1989，44，5： | 1 |
| 19 | Detrimental effects of overstuffing or understuffing with a radial head replacement in the medial collateralligament deficient elbow 显示文摘 | Van Glabbeek F Van Riet RP Baumfeld JA | 2004 | J Bone Joint Surg(Am)2004，，86： | 1 |
| 20 | Use of osteochondral bone graft in coronoid fracture显示文摘 | Van Riet RP Morrey BF O' Driscoll SW | 2005 | J Shoulder Elbow Surg2005，5，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员