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| 1 | Percutaneous nephrolithotomy in pediatric age group:Assessment of effectiveness and complications显示文摘Management of kidney stone disease in pediatric population is a challenging condition in urology practice. While the incidence of kidney stone is increasing in those group, technological innovations have conrtibuted to the development of minimally invasive treatment of urinary stone disease such as mini-percutenous nephrolitotomy(mini-PCNL), micro-PCNL, ultra mini-PCNL. In this review we tried to evaluate the effect of new teratment techniques on pediatric kidney stones. | Ender Ozden Mehmet Necmettin Mercimek | 2016 | World Journal of Nephrology2016，5，1： | 12 |
| 2 | Survival in gastric cancer in relation to postoperative adjuvant therapy and determinants显示文摘AIM: To evaluate survival data in patients with gastric cancer in relation to postoperative adjuvant therapy and survival determinantsMETHODS: A total of 201 patients(mean ± SD age: 56.0 ± 11.9 years, 69.7% were males) with gastric carcinoma who were operated and followed up at Lutfi Kirdar Kartal Training and Research Hospital between 1998 and 2010 were included in this retrospective study. Follow up was evaluated divided into two consecutive periods(before 2008 and 2008-2010, respectively) based on introduction of 3-D conformal technique in radiotherapy at our clinic in 2008. Data on patient demographics, clinical and histopathological characteristics of gastric carcinoma and the type of treatment applied after surgery [postoperative adjuvant treatment protocols including chemoradiotherapy(CRT) and chemotherapy(CT), supportive therapy or follow up without any treatment] were recorded. The median duration and determinants of local recurrence free(LRF) survival, distant metastasis free(DMF) survival and overall survival were evaluated in the overall population as well as with respect to follow up years [1998-2008(n = 127) vs 2008-2010(n = 74)].RESULTS: Median duration for LRF survival, DMF survival and overall survival were 31.9, 24.1 and 31.9 mo, respectively in patients with postoperative adjuvant CRT. No significant difference was noted in median duration for LRF survival, DMF survival and overall survival with respect to treatment protocols in the overall population and also with respect to followed up periods. In the overall population, CT protocols FUFA [5-fluorouracil(400 mg/m2) and leucovorin-folinic acid(FA, 20 mg/m2)](29.9 mo) and UFT + Antre [a fixed combination of the oral FU prodrug tegafur(flouroprymidine, FT, 300 mg/m2 per day) with FA(Antrex?), 15 mg tablet, two times a day](42.5 mo) was significantly associated with longer LRF survival times than other CT protocols(P = 0.036), while no difference was noted between CT protocols in terms of DMF survival and overall survival. Among patients received CRT, overall survival was significantly longer in patients with negative than positive surgical margin(27.7 mo vs 22.4 mo, P = 0.016) in the overallstudy population, while time of radiotherapy initiation had no significant impact on survival times. Nodal stage was determined to be independent predictor of LRF survival in the overall study population with 4.959 fold(P = 0.042) increase in mortality in patients with nodal stage N2 compared to patients with nodal stage N0, and independent predictor of overall survival with 5.132 fold(P = 0.006), 5.263 fold(P = 0.027) and 4.056 fold(P = 0.009) increase in the mortality in patients with nodal stage N3a(before 2008), N3b(before 2008) and N2(overall study population) when compared to patients with N0 stage, respectively.CONCLUSION: Our findings emphasize the likelihood of postoperative adjuvant CRT to have a survival benefit in patients with resectable gastric carcinoma. | Sevgi Ozden Zerrin Ozgen Hazan Ozyurt Cengiz Gemici Gokhan Yaprak Huseyin Tepetam Alpaslan Mayadagli | 2015 | World Journal of Gastroenterology2015，21，4： | 7 |
| 3 | Pegylated interferon-alpha plus taurine in treatment of rat liver fibrosis显示文摘AIM: To investigate the antif ibrotic effects of peginterferon- alpha 2b and taurine on oxidative stress markers and hepatocellular apoptosis. METHODS: Sixty rats with CCl4-induced liver fibrosis were divided into 4 groups (n = 15). Group 1 was left for spontaneous recovery (SR). Groups 2-4 received peginterferon-alpha 2b, taurine, and their combination, respectively, for four weeks. Histological f ibrosis scores, histomorphometric analysis, tissue hydroxyproline, tissue MDA, GPx and SOD activities were determined. Activated stellate cells and hepatocellular apoptosis were also evaluated. RESULTS: The degree of f ibrosis decreased in all treatment groups compared to spontaneous recovery group. Taurine alone and in combination with peginterferon-alpha 2b reduced oxidative stress markers, but peginterferon-alpha 2b alone did not. Apoptotic hepatocytes and activated stellate cells were higher in groups 2-4 than in group 1. Combined taurine and peginterferon-alpha 2b further reduced fibrosis and increased activated stellate cell apoptosis, but could not improve oxidative stress more than taurine alone.CONCLUSION: Peginterferon-alpha 2b exerts anti- f ibrotic effects on rat liver fibrosis. It seems ineffective against oxidative stress in vivo. Peginterferon-alpha 2b in combination with taurine seems to be an antif ibrotic strategy. | Ilker Tasci Mehmet Refik Mas Sevil Atalay Vural Salih Deveci Bilgin Comert Gunay Alcigir Nuket Mas Cemal Akay Mithat Bozdayi Cihan Yurdaydin Hakan Bozkaya Ozden Uzunalimoglu Ahmet Turan Isik Harun M Said | 2007 | World Journal of Gastroenterology2007，13，23： | 7 |
| 4 | Prognostic role of sensitive-to-apoptosis gene expression in rectal cancer显示文摘AIM:To investigate the association between prognosis of rectal cancer treated with chemoradiotherapy(CRT) and expression of sensitive-to-apoptosis(SAG),B-cell lymphoma-extra large(Bcl-X L) and Bcl-2 homologous antagonist/killer(Bak).METHODS:Real-time quantitative polymerase chain reaction was used to determine the expression of proteins of interest,namely SAG,Bcl-X L,Bak and β-actin,in rectal carcinoma patients who had a follow-up period of 3 years after CRT.Biopsy specimens were excised from the rectal tumor preceding CRT.RESULTS:SAG,Bcl-X L and Bak proteins showed significant correlations with each other.In multivariate analysis,patients with high vs low SAG expression showed a statistically significant difference in 2-year survival rates:56% vs 73%,respectively(P = 0.056).On the other hand,there were no significant correlations between the expression levels of all three genes and metastatic rates or tumor responses to CRT.Mean overall survival in the patients with elevated SAG expression was 27.1 mo ± 3.9 mo [95% confidence interval(CI):19.3-34.9],and in patients with reduced expression,it was 32.1 mo ± 2.5 mo(95% CI:27.3-36.9).The corresponding values for Bcl-X L were 28.0 mo ± 4.1 mo(95% CI:19.9-36.1) and 31.7 mo ± 2.9 mo(95% CI:26.0-37.5),and those for Bak were 29.8 mo ± 3.7 mo(95% CI:22.5-37.2) and 30.6 mo ± 2.4 mo(95% CI:25.5-35.0),respectively.CONCLUSION:Two-year survival rates significantly correlated with low SAG expression,and SAG may be a candidate gene for good prognosis,independent of therapeutic response of different individuals. | Sevgi A Ozden Hazan Ozyurt Zerrin Ozgen Olca Kilinc Mustafa Oncel Aylin E Gul Nimet Karadayi Nedime Serakinci Beki Kan Oya Orun | 2011 | World Journal of Gastroenterology2011，17，44： | 6 |
| 5 | A PURCHASING DECISION: SELECTING A SUPPLIER FOR A CONSTRUCTION COMPANY显示文摘Supplier selection is one of the most crucial activities performed by organizations because of its strategic importance. Supplier selection is a multi-objective problem involving both quantitative and qualitative criteria. Over the years a number of quantitative approaches have been tried. Although the Analytic Hierarchy Process (AHP) has previously been used in supplier selection problems, one major weakness of the application-oriented AHP literature is that it tends to focus on the mechanics of AHP instead of on the theoretical and practical implications associated with finding a solution. Though it is one of the most extensively used Multiple Criteria Decision Analysis methodologies, our literature search indicated that most studies found the best solution and stopped there, ignoring sensitivity analysis. Performing sensitivity analysis is very important for practical decision making, sometimes even as important as finding the best solution. In this paper for the first time a comprehensive application of AHP for a real-world case is presented along with sensitivity analysis in choosing the best suppliers for a Turkish construction company. As a result of this study the company decided to allocate the order quantities between the two top suppliers. | Ozden BAYAZIT Birsen KARPAK Ayhan YAGCI | 2006 | Journal of Systems Science and Systems Engineering2006，15，2： | 3 |
| 6 | SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress显示文摘 | Hyun-Seok Kim Krish Patel Kristi Muldoon-Jacobs Kheem S. Bisht Nukhet Aykin-Burns J. Daniel Pennington Riet van der Meer Phuongmai Nguyen Jason Savage Kjerstin M. Owens Athanassios Vassilopoulos Ozkan Ozden Seong-Hoon Park Keshav K. Singh Sarki A. Abdulka | 2010 | Cancer Cell2010，，1： | 3 |
| 7 | Finite Element Analysis of Drilling of Carbon Fibre Reinforced Composites显示文摘 | Ozden Isbilir Elaheh Ghassemieh | 2012 | Applied Composite Materials2012，，3： | 2 |
| 8 | Single session removal of forgotten encrusted ureteral stents: combined endourological approach显示文摘 | Yakup Bostanci Ender Ozden Fatih Atac Yarkin Yakupoglu Ali Yilmaz Saban Sarikaya | 2012 | Urological Research2012，，5： | 2 |
| 9 | Numerical Simulation of the Flow around Two-dimensional Partially Cavitating Hydrofoils显示文摘在现在的学习,一条新途径被用于洞预言为二维(2D ) 由潜力的水翼船基于边界元素方法(BEM ) 。边界元素方法被 Dirichlet 类型边界条件的使用在面板表面和洞表面上与来源和马甲分布一起对待。一条反复的答案途径被用来决定洞形状在上部分 cavitating 水翼船。在一个指定成穴数字和洞长度的情况中,反复的答案方法由排水量厚度的增加或减法继续水翼船的洞表面。适当的洞形状被洞表面的动态边界条件和整个陪衬表面的运动学的边界条件包括洞获得。为一个给定的成穴数字, 2D 水翼船的洞长度在不同的洞长度之中根据最小的错误标准被决定,它在洞表面上满足动态边界条件。NACA 16006, NACA 16012 和 NACA 16015 水翼船节为攻击的二个角度被调查。结果与另外的潜在的基于的边界元素代码, PCPAN 和商业 CFD 代码相比(流畅) 。因而,从二条维的途径获得的结果与那些从其它获得了一致,这被显示出。 | Fahri Celik Yasemin Arikan Ozden Sakir Bal | 2014 | Journal of Marine Science and Application2014，13，3： | 2 |
| 10 | Evaluation of 532-nm KTP laser treatment efficacy on acne vulgaris with once and twice weekly applications显示文摘 | Ozlem Yilmaz Nilgun Senturk Esra Pancar Yuksel Fatma Aydin Muge Guler Ozden Tayyar Canturk Ahmetyasar Turanli | 2011 | Journal of Cosmetic and Laser Therapy2011，，6： | 2 |
| 11 | Gastric, duodenal, and pancreatic somatostatin-like immunoreactivity during hypovolemic shock显示文摘 | David Wiles Oktay Yeginsu MD Ali Ozden MD Steve M. Covington MD Janet Rice PhD Atilla Ertan MD | 1988 | Digestive Diseases and Sciences1988，，7： | 2 |
| 12 | Effect of urinary stone disease and its treatment on renal function显示文摘Urolithiasis is a common disease that affects urinary tract in all age groups. Both in adults and in children, stone size, location, renal anatomy, and other factors, can influence the success of treatment modalities. Recently, there has been a great advancement in technology for minimally invasive management of urinary stones. The epoch of open treatment modalities has passed and currently there are much less invasive treatment approaches, such as percutaneous nephrolithotomy, ureteroscopy, shockwave lithotripsy, and retrograde internal Surgery. Furthermore, advancement in imaging technics ensures substantial knowledge that permit physician to decide the most convenient treatment method for the patient. Thus, effective and rapid treatment of urinary tract stones is substantial for the preservation of the renal function. In this review, the effects of the treatment options for urinary stones on renal function have been reviewed. | Necmettin Mercimek Mehmet Ozden Ender | 2015 | World Journal of Nephrology2015，4，2： | 2 |
| 13 | SIRT3,mitochon- drial ROS, ageing, and carcinogenesis 显示文摘 | Park S H Ozden O Jiang H | 2011 | Int J Mol Sci2011，12，9： | 1 |
| 14 | Sirt3, mitochondrial ROS, aging, and carcinogenesis 显示文摘 | Park S H Ozden O Jiang H | 2011 | International Journal of Molecular Sciences2011，12，9： | 1 |
| 15 | Relationship between plasmacystatin C and Creatinine in chronic renal diseases and Tx2 trans-plant patients显示文摘 | Gokkusu CA Ozden T Gul H | 2004 | Clin Biochem2004，32，2： | 1 |
| 16 | Epithelial-Mesenchymal Tran- sition Markers β-catenin, Snail, and E-Cadherin do not Predict Disease Free Survival in Prostate Adenoearcinoma: a Prospec- tive Study 显示文摘 | Ipekei T Ozden F Unal B | 2015 | Pathol Oncol Res2015，21，4： | 1 |
| 17 | Graphical Programming of Simulation Models in an Object-Oriented Environment显示文摘 | | 1991 | Simulation1991，56，2： | 1 |
| 18 | Accelerated ageing test of aubergine,cucumber and melon seeds in relation to time and temperature variables 显示文摘 | Demir I Ozden Y S Yilmaz K | 2004 | Seed Science and Technology2004，32，： | 1 |
| 19 | Protective effect of ischemic preconditioning on retinal ischemia-reperfusion injury in rats显示文摘 | Ozbay D Ozden S Muftuoglu S Kaymaz F Yaylali V Yildi-rim C | 2004 | Can J Ophthalmol2004，39，： | 1 |
| 20 | Molecular mechanisms of HIV-1 associated neurodegeneration显示文摘 | Ozdener H | 2005 | J Bio Sci2005，30，3： | 1 |
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