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| 1 | Comparison of different lymph node staging systems in prognosis of gastric cancer:a bi-institutional study from Hungary显示文摘Objective: The Union for International Cancer Control(UICC) Node(N) classification is the most common used staging method for the prognosis of gastric cancer. It demands adequate, at least 16 lymph nodes(LNs) to be dissected; therefore different staging systems were invented.Methods: Between March 2005 and March 2010, 164 patients were evaluated at the Department of General Surgery in the Kenézy Gyula Hospital and at the Department of General, Thoracic and Vascular Surgery in the Kaposi Mór Hospital. The 6th, 7th and 8th UICC N-staging systems, the number of examined LNs, the number of harvested negative LNs, the metastatic lymph node ratio(MLR) and the log odds of positive LNs(LODDS) were determined to measure their 5-year survival rates and to compare them to each other.Results: The overall 5-year survival rate for all patients was 55.5% with a median overall survival time of 102 months. The tumor stage, gender, UICC N-stages, MLR and the LODDS were significant prognostic factors for the 5-year survival with univariate analysis. The 6th UICC N-stage did not follow the adequate risk in comparing N2 vs. N0 and N3 vs. N0 with multivariate investigation. Comparison of performances of the residual N classifications proved that the LODDS system was first in the prediction of prognosis during the evaluation of all patients and in cases with less than 16 harvested LNs. The MLR gave the best prognostic prediction when adequate(more than or equal to 16) lymphadenectomy was performed.Conclusions: We suggest the application of LODDS system routinely in western patients and the usage of MLR classification in cases with extended lymphadenectomy. | dezso tóth adrienn bíró zsolt varga miklós torok péterárkosy | 2017 | Chinese Journal of Cancer Research2017，29，4： | 4 |
| 2 | No association of the cytotoxic T-lymphocyte associated gene CTLA4 +49A/G polymorphisms with Crohn's disease and ulcerative colitis in Hungarian population samples显示文摘瞄准:当前的工作的目标细胞毒素的 T 淋巴细胞抗原是分析 +49A/G 的流行变体的在有 Crohn 的匈牙利病人的 4 基因(CTLA4 )?ˉs 疾病(CD ) 和 ulcerative (UC ) 。方法:有 CD 的 130 个无关的题目的一个总数并且 150 与 UC,和 170 匹配的控制是为单个核苷酸多型性(SNP ) 的 genotyped。遗传型被使用 PCR/RFLP 测试决定。结果:G 等位基因频率和 GG 遗传型的流行在 CD 组,是 38.1% 和 12.3%40.6% 和 18.6% 在 UC 病人,并且 37.4% 和 15.9% 在控制组分别地。结论:当前的学习的结果显示出 +49G SNP 的那辆马车在异质接合或不在匈牙利人口为 CD 或为 UC 在同型结合的形式授与风险任何一个。 | Lili Magyari Bernadett Faragó Judit Bene Katalin Horvatovich Lilla Lakner Márta Varga Mária Figler Beáta Gasztonyi Gyula Mózsik Béla Melegh | 2007 | World Journal of Gastroenterology2007，13，15： | 3 |
| 3 | Interaction of the major inflammatory bowel disease susceptibility alleles in Crohn’s disease patients显示文摘AIM:To investigate the interaction of interleukin-23 receptor(IL23R)(rs1004819 and rs2201841),autophagy-related 16-like 1(ATG16L1)(rs2241880), caspase recruitment domain-containing protein 15 (CARD15)genes,and IBD5 locus in Crohn's disease(CD) patients. METHODS:A total of 315 unrelated subjects with CD and 314 healthy controls were genotyped.Interactions and specific genotype combinations of a total of eight variants were tested.The variants of IBD5locus(IGR2198a_1 rs11739135 and IGR2096a_1 rs12521868),CARD15(R702W rs2066845 and L1007fs rs2066847),ATG16L1(rs2241880)and IL23R (rs1004819,rs2201841)genes were genotyped by PCR-RFLP,the G908R(rs2066844)in CARD15 was determined by direct sequencing. RESULTS:The association of ATG16L1 T300A with CD was confirmed[P=0.004,odds ratio(OR)=1.69, 95%CI:1.19-2.41],and both IL23R variants were found to represent significant risk for the disease(P= 0.008,OR=2.05,95%CI:1.20-3.50 for rs1004819 AA;P<0.001,OR=2.97,95%CI:1.65-5.33 for rs2201841 CC).Logistic regression analysis of pairwise interaction of the inflammatory bowel disease (IBD)loci indicated that IL23R,ATG16L1,CARD15 and IBD5(IGR2198a_1)contribute independently to disease risk.We also analysed the specific combina- tions by pair of individual ATG16L1,IL23R rs1004819, rs2201841,IGR2198a_1,IGR2096a_1 and CARD15 genotypes for disease risk influence.In almost all cases,the combined risk of susceptibility pairs was higher in patients carrying two different risk-associated gene variants together than individuals with just one polymorphism.The highest OR was found for IL23R rs2201841 homozygous genotype with combination of positive CARD15 status(P<0.001,OR=9.15,95% CI:2.05-40.74). CONCLUSION:The present study suggests a cumulative effect of individual IBD susceptibility loci. | Veronika Csngei Luca Járomi EnikSáfrány Csilla Sipeky Lili Magyari Bernadett Faragó Judit Bene Noémi Polgár Lilla Lakner Patrícia Sarlós Márta Varga Béla Melegh | 2010 | World Journal of Gastroenterology2010，16，2： | 2 |
| 4 | Residual solvents determination in pharmaceutical products by GC-HS and GCMS-SPME 显示文摘 | Camarasu C C Mezei-Szuts M Varga G B | 1998 | J Pharm Biomed Anal1998，18，45： | 1 |
| 5 | Determination of trace elements in human liver biopsy samples by ICP–MS and TXRF: hepatic steatosis and nickel accumulation显示文摘 | Imre Varga ágnes Szebeni Norbert Szoboszlai Béla Kovács | 2005 | Analytical and Bioanalytical Chemistry2005，，3： | 1 |
| 6 | Adhesives and cements to promote preservation dentistry显示文摘 | Van Meebeek B Vargas M Inoue S | | 0，，6： | 1 |
| 7 | Study of humic-like substances in fog and interstitial aerosol by size-exclusion chromatography and capillary electrophoresis显示文摘 | Z Krivácsy Gy Kiss B Varga I Galambos Zs Sárvári A Gelencsér á Molnár S Fuzzi M.C Facchini S Zappoli A Andracchio T Alsberg H.C Hansson L Persson | 2000 | Atmospheric Environment2000，，25： | 1 |
| 8 | Net absorption and oxygen consumption by Holstein steers fed alfalfa or orchard grass silage at two equalized intakes显示文摘 | Huntington G B Varga G A Ulenn B Y | 1988 | J Anim Sci1988，6，： | 1 |
| 9 | Assessing the relationship between children' s oral health status and that of their mothers 显示文摘 | Dye B A Vargas C M Lee J J | 2011 | The Journal of the American Dental Association2011，142，2： | 1 |
| 10 | Platelets stimulate prolifera- tion of bone cells: involvement of platelet-derived growth factor, mi- croparticles and membranes 显示文摘 | Gruber R Varga F Fischer M B | 2002 | Clinical Oral Implants Research2002，13，5： | 1 |
| 11 | Analysis of a solarassisted ejector cooling system for air conditioning显示文摘 | Varga S C Oliveira A Diaconu B | 2009 | International Journal of Low-Carbon Technologies2009，4，1： | 1 |
| 12 | The color and texture of broiler breast meat related to different condition of rearing and chilling显示文摘 | GASPERLIN L ZLENDER B VARGA C | 1999 | Acta Agaraia Kaposvariensis1999，3，2： | 1 |
| 13 | Bioleaching of refractory gold concentrates at high pulp densities in a nonconventional rotating-drum reactor 显示文摘 | HERRERA M N ESCOBAR B PARRA N GONZALEZ C VARGAS T | 1998 | Minerals and Metallurgy Processing1998，15，： | 1 |
| 14 | Crude extracts of bacterially expressed dsRNA can be used to protect plants against virus infections显示文摘 | Tenllado F Martinez-Garcia B Vargas M | 2003 | BMC biotechnology2003，3，1： | 1 |
| 15 | Crude ex- tracts of bacterially expressed dsRxNA can be used to protect plants a- gainst virus infections 显示文摘 | TENLLADO F MARTINEZ- GARCIA B VARGAS M | 2003 | BMC Biotechnalogy2003，3，3： | 1 |
| 16 | Complications of llizarov leg lengthening: a comparative study between patients with leg length dis- crepancy and short stature显示文摘 | Vargas Barreto B Caton J Merabet Z | 2007 | Int Orthop2007，31，： | 1 |
| 17 | Organophosphate effects on antioxidant system of carp (Cyprinus carpio) and catfish (lctalurus nebulosus )显示文摘 | Hai D Q Varga S I Matkovics B | 1997 | Comparative Bio?chemistry and Physiology Part C: Pharmacology Toxi?cology and Endocrinology1997，117，1： | 1 |
| 18 | Heavy metals dynamics in seaweeds and seagrasses in Bahia Magdalena, BCS, Mexico显示文摘 | Riosmena-Rodriguez R Talavera-Saenz A Acosta- Vargas B | 2010 | Journal of Applied Phycology2010，22，3： | 1 |
| 19 | High Solid Simultaneous Saccharification and Fermentation of Wet Oxidized Corn Stover to Ethanol 显示文摘 | Eniko Varga Helene B Klinke Kati Reczey | 2004 | Biotechnol &Bioengin2004，88，5： | 1 |
| 20 | Evaluation of Oviposition Stimulants for Mass Production of Melon Fly, Oriental Fruit Fly, and Mediterranean Fruit Fly ( (Diptera: Tephritidae) 显示文摘 | Roger I Vargas Harris B | 1991 | J Econ Entomol1991，84，6： | 1 |
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