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| 1 | Antibacterial and Antibiotic-Potentiation Activities of Some Cameroonian Food Plants against Multi-Drug Resistant Gram-Negative Bacteria显示文摘Objective:To evaluate the in vitro antibacterial properties and the ability to potentiate some common antibiotics effects of the methanol extracts of 11 Cameroonian food plants on 29 Gram-negative bacteria expressing multidrug resistant(MDR) phenotypes.Methods:The antimicrobial activity of the extracts was performed using the broth microdilution method.The phytochemical screening of these extracts was also performed using standard methods.Resutts:Ocimum basilicum,Gnetum africanum and Eucalyptus robusta extracts possessed an antibacterial activity against all the 29 studied bacteria.The extracts from G.africanum and E.robusta were the most active with the lowest minimal inhibitory concentration of 64 μg/mL on Escherichia coli AG100 A for both extracts and also against Klebsiella pneumoniae K24 for G.africanum.When tested in the presence of phenylalanine-arginine β-Naphtylamide(PA β N),an efflux pump inhibitor,the extract of Thymus vulgaris and E.Robusta showed the best activities on most tested strains.E.Robusta extract showed good synergistic effects,improving the activity of commonly used antibiotics in about 85%of cases.Conclusion:The overall results obtained provide the baseline information for the use of the tested plants in the treatment of bacterial infections. | Simplice B.Tankeo Stephen T.Lacmata Jaures A.K.Noumedem Jean P.Dzoyem Jules R Kuiate Victor Kuete | 2014 | Chinese Journal of Integrative Medicine2014，20，7： | 7 |
| 2 | Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。 | R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren | 2011 | Cell Research2011，21，10： | 6 |
| 3 | Transradial approach for acute stroke intervention: technical procedure and clinical outcomes显示文摘background and purpose Radial artery catheterisation is an alternate route of access that has recently started to gain more widespread use for neuroendovascular procedures,including acute stroke intervention.In this small case series,we present our institution’s outcomes in patients undergoing acute stroke interventions via transradial access.Materials and methods We present a retrospective study of 15 patients who underwent acute stroke intervention via radial artery access.We analyse these patients’periprocedural and clinical outcomes after undergoing mechanical thrombectomy.results A total of 15 consecutive patients were included in the study(9 males and 6 females),and all patients were able to successfully undergo mechanical thrombectomy via radial artery access.The mean time of arterial puncture to reperfusion was 50±28 min(range:15-104).A TICI 2b/3 revascularisation was achieved in 13/15 patients(87%);a TICI 1 and TICI 2a outcome was achieved on the other two patients.One patient incurred an iatrogenic vessel dissection during the procedure.Eight of out 15 patients(53%)had favourable mRS(0-3)at the time of discharge from the hospital.Conclusion Radial artery catheterisation is technically feasible for performing acute stroke interventions with favourable time to revascularisation and good overall clinical outcomes. | Omaditya Khanna Nikolaos Mouchtouris Ahmad Sweid Nohra Chalouhi Ritam Ghosh Fadi Al Saiegh Michael R Gooch Stavropoula Tjoumakaris Robert H Rosenwasser Victor Romo Pascal Jabbour | 2020 | Stroke & Vascular Neurology2020，5，1： | 4 |
| 4 | Screening for hepatocellular carcinoma in patients with hepatitis C cirrhosis: a cost-utility analysis显示文摘 | Miguel R Arguedas Victor K Chen Mohamad A Eloubeidi Michael B Fallon | 2003 | The American Journal of Gastroenterology2003，，3： | 3 |
| 5 | The DA VINCI Study: Phase 2 Primary Results of VEGF Trap-Eye in Patients with Diabetic Macular Edema显示文摘 | Diana V. Do Ursula Schmidt-Erfurth Victor H. Gonzalez Carmelina M. Gordon Michael Tolentino Alyson J. Berliner Robert Vitti Rene Rückert Rupert Sandbrink David Stein Ke Yang Karola Beckmann Jeff S. Heier | 2011 | Ophthalmology2011，，9： | 3 |
| 6 | Interfering with Gal-1–mediated angiogenesis contributes to the pathogenesis of preeclampsia显示文摘 | Nancy Freitag Irene Tirado-González Gabriela Barrientos Florian Herse Victor L. J. L. Thijssen Susanne M. Weedon-Fekj?r Herbert Schulz Gerd Wallukat Burghard F. Klapp Tania Nevers Surendra Sharma Anne Cathrine Staff Ralf Dechend Sandra M. Blois | 2013 | Proceedings of the National Academy of Sciences2013，，28： | 2 |
| 7 | Acute ischaemic stroke interventions: large vessel occlusion and beyond显示文摘Care for acute ischaemic stroke is one of the most rapidly evolving fields due to the robust outcomes achieved by mechanical thrombectomy.Large vessel occlusion(LVO)accounts for up to 38%of acute ischaemic stroke and comes with devastating outcomes for patients,families and society in the pre-intervention era.A paradigm shift and a breakthrough brought mechanical thrombectomy back into the spotlight for acute ischaemic stroke;this was because five randomised controlled trials from several countries concluded that mechanical thrombectomy for acute stroke offered overwhelming benefits.This review article will present a comprehensive overview of LVO management,techniques and devices used,and the future of stroke therapy.In addition,we review our institution experience of mechanical thrombectomy for posterior and distal circulation occlusion. | Ahmad Sweid Batoul Hammoud Sunidhi Ramesh Daniella Wong Tyler D Alexander Joshua Harrison Weinberg Maureen Deprince Jaime Dougherty Dimitri Jean-Mickael Maamari Stavropoula Tjoumakaris Hekmat Zarzour Michael R Gooch Nabeel Herial Victor Romo David M Hasan Robert H Rosenwasser Pascal Jabbour | 2020 | Stroke & Vascular Neurology2020，5，1： | 2 |
| 8 | Imaging pancreatobiliary ductal system with optical coherence tomography: A review显示文摘An accurate, noninvasive and cost-effective method of in situ tissue evaluation during endoscopy would be highly advantageous for the detection of dysplasia or early cancer and for identifying different disease stages. Optical coherence tomography(OCT) is a noninvasive, high-resolution(1-10 μm) emerging optical imaging method with potential for identifying microscopic subsurface features in the pancreatic and biliary ductal system. Tissue microstructure of pancreaticobiliary ductal system has been successfully imaged by inserting an OCT probe through a standard endoscope operative channel. High-resolution OCT images and the technique's endoscopic compatibility have allowed for the microstructural diagnostic of thepancreatobiliary diseases. In this review, we discussed currently available pancreaticobiliary ductal imaging systems to assess the pancreatobiliary tissue microstructure and to evaluate varieties of pancreaticobiliary disorders and diseases. Results show that OCT can improve the quality of images of pancreatobiliary system during endoscopic retrograde cholangiopancheatography procedure, which may be important in distinguishing between the neoplastic and non-neoplastic lesions. | Mohammad S Mahmud Gray R May Mohammad M Kamal Ahmed S Khwaja Carry Sun Alex Vitkin Victor XD Yang | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，11： | 2 |
| 9 | Comparison of neural network models with ARIMA and regression models for prediction of Houston's daily maximum ozone concentrations 显示文摘 | Victor R Prybutok Junsub Yi and David Mitchell | 2000 | European Journal of Operational Research2000，122，： | 1 |
| 10 | A surface plasmon resonance array biosensor based on spectroscopic imaging显示文摘 | Michael J O Brien I I Victor H Perez-Luna Brueck S R J | 2001 | Biosensors Bioelectronics2001，16，： | 1 |
| 11 | Imaging xanthan gum in air by ac “tapping” mode atomic force microscopy显示文摘 | Patrick Gunning Andrew R Kirby Victor J Morris | 1996 | Ultramicroscopy1996，63，： | 1 |
| 12 | Central pontinemyelinolysis: a hitherto undescribed disease occurring in alcoholic and malnourished patients 显示文摘 | Adams R D Victor M Mancall E L | 1959 | AMA Arch Neurol Psychiatry1959，81，4： | 1 |
| 13 | Phenotypie plasticity of stem water potential correlates with crop load in horticultural trees 显示文摘 | Victor O S Eduardo R T | 2011 | Tree Physiology2011，31，： | 1 |
| 14 | A Novel Cryptosystem Based on Grey Sys - tem Theory and Genetic Algorithm 显示文摘 | Victor R L | 2005 | Applied Mathe- matics and Computation2005，170，2： | 1 |
| 15 | Generalizing the partial global planning algorithm 显示文摘 | Decker Keith S Lesser Victor R | 1992 | International Journal of Intelligent and Cooperative Information System1992，1，2： | 1 |
| 16 | Measuring and testing the impact of news on volatility 显示文摘 | Engle R F Victor K N G | 1993 | Journal of Finance1993，48，： | 1 |
| 17 | No evidence for point mutation in codons 12, 13 and 61 of the ras gene in a high incidence area for esophageal and gastric cancer显示文摘 | Victor T Du Toit R Jordaan AM el at | 1990 | Cancer Res1990，50，16： | 1 |
| 18 | A bar- ber- based intervention for hypertension in African American men: design of a group randomized trial 显示文摘 | VICTOR R G RAVENELL J E FREEMAN A | 2009 | The American heart journal2009，157，1： | 1 |
| 19 | Inhibition of Desuvovibrio gigas hydrogenase with copper salts and other metalions显示文摘 | VICTOR M F MARIA L R PRESENTACION R | 1989 | European Journal of Biochemistry1989，185，2： | 1 |
| 20 | Generalizing the partial global planning algorithm 显示文摘 | Keith S Decker Victor R Lesser | 1992 | Intemational Journal of Intelligent and Cooperative Information Systems1992，，2： | 1 |
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