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| 1 | The complete reference genome for grapevine (Vitis vinifera L.) genetics and breeding显示文摘Grapevine is one of the most economically important crops worldwide.However,the previous versions of the grapevine reference genome tipically consist of thousands of fragments with missing centromeres and telomeres,limiting the accessibility of the repetitive sequences,the centromeric and telomeric regions,and the study of inheritance of important agronomic traits in these regions.Here,we assembled a telomere-to-telomere(T2T)gap-free reference genome for the cultivar PN40024 using PacBio HiFi long reads.The T2T reference genome(PN_T2T)is 69 Mb longer with 9018 more genes identified than the 12X.v0 version.We annotated 67%repetitive sequences,19 centromeres and 36 telomeres,and incorporated gene annotations of previous versions into the PN_T2T assembly.We detected a total of 377 gene clusters,which showed associations with complex traits,such as aroma and disease resistance.Even though PN40024 derives from nine generations of selfing,we still found nine genomic hotspots of heterozygous sites associated with biological processes,such as the oxidation–reduction process and protein phosphorylation.The fully annotated complete reference genome therefore constitutes an important resource for grapevine genetic studies and breeding programs. | Xiaoya Shi Shuo Cao Xu Wang Siyang Huang Yue Wang Zhongjie Liu Wenwen Liu Xiangpeng Leng Yanling Peng Nan Wang Yiwen Wang Zhiyao Ma Xiaodong Xu Fan Zhang Hui Xue Haixia Zhong Yi Wang Kekun Zhang Amandine Velt Komlan Avia Daniela Holtgräwe Jérôme Grimplet JoséTomás Matus Doreen Ware Xinyu Wu Haibo Wang Chonghuai Liu Yuling Fang Camille Rustenholz Zongming Cheng Hua Xiao Yongfeng Zhou | 2023 | Horticulture Research2023，10，5： | 3 |
| 2 | Mild cognitive impairment:clinical characterization and out come显示文摘 | Petersen R Smith G Waring S | 1999 | Arch Neurol1999，56，： | 1 |
| 3 | Mild cognitive impairment: clinical characterization and outcome 显示文摘 | Petersen R C Smith G E Waring S C | 1999 | Arch Neural1999，56，3： | 1 |
| 4 | Glycosyl-phosphatidylinositol anchor synthesis in paroxysmal nocturnal hemoglobinuria:partial or complete defect in an early step显示文摘 | Norris J Hall S ware R E | | 0，，03： | 1 |
| 5 | Mild cognitive impairment:clinical characterization and outcome显示文摘 | PETERSEN R C SMITH G E WARING S C | 1999 | Archives of Neurology1999，56，3： | 1 |
| 6 | Mild cognitive impairment: Clinical characterization and outcome 显示文摘 | Petersen R C Smith G E Waring S C | 1999 | Arch Neurol1999，56，3： | 1 |
| 7 | Mild cognitive impairment: clinical characterization and outcome 显示文摘 | Petersen R C Smith G E Waring S C | 1999 | Arch Neurol1999，56，3： | 1 |
| 8 | Precision of geomagnetic field measurements in a tectonically active region显示文摘 | Johnston M J S Mueller R J Ware R H | 1984 | J Geomag Geoelectr1984，36，： | 1 |
| 9 | Comparisons of predictions of net primary production and seasonal patterns in water use derived with two forest growth models in Southwestern Oregon显示文摘 | Coops N C Waring R H Brown S R | 2001 | Ecological Modelling2001，142，： | 1 |
| 10 | Mild cognitive impairment: clinical characterization and outcome显示文摘 | Petersen R C Smith G E Waring S C | 1999 | Arch Neurol1999，56，3： | 1 |
| 11 | Mild cognitive im- pairment : clinical characterization and outcome 显示文摘 | Petersen R C Smith G E Waring S C | 1999 | Arch Neurol1999，56，3： | 1 |
| 12 | Mild cognitive impairment: Clinical characterization and outcome 显示文摘 | Petersen R C Smith G E Waring S C | 1999 | Arch Neurol1999，56，3： | 1 |
| 13 | The B73 maize genome:Complexity, diversity, and dynamics 显示文摘 | Schnable P S Ware D Fulton R S | 2009 | Science2009，326，11： | 1 |
| 14 | The B73 maize genome : complexity, diversity, and dynamics 显示文摘 | SCHNABLE P S WARE D FULTON R S | 2009 | Sci- ence2009，326，： | 1 |
| 15 | Mild cognitive impairment: clinical characterization and outcome 显示文摘 | PETERSEN R C SMITH G E WARING S C | 1999 | Archives of Neurology1999，56，3： | 1 |
| 16 | Sapwood water storage : its contribution to transpiration and effect upon water conductance through the stems of old-growth Douglas-fir显示文摘 | Waring R H Running S W | 1978 | Plant Cell and Environment1978，1，： | 1 |
| 17 | A mixed non-linear program to model dynamic supplier selection problem 显示文摘 | Ware N R Singh S P Banwet D K | 2014 | Expert Systems with Applications2014，41，67： | 1 |
| 18 | Effectiveness of a randomized controlled lifestyle intervention to prevent obesity among Chinese pri- mary school students: CLICK-obesity study显示文摘 | XU F WARE R S LESLIE E | 2015 | PLuS One2015，10，01： | 1 |
| 19 | Mild cognitive impairment:clinical characterization and outcome显示文摘 | Smith G E Waring S C | 1999 | Arch Neurol1999，56，： | 1 |
| 20 | De'Jelopment and mapping of 2240 new SSR markers for rice (Oryza sativa L, ) 显示文摘 | McCouch S R Teytelman L Xu Y B Lobos K B Clare K Walton M Fu B Maghiran R Li Z Xing Y Zhang Q Kono I Yano M Jellstrom R F Declcrck G Schneider D Cartinhour S Ware D Stein L | 2002 | DNA Research2002，9，： | 1 |
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