|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Psychosocial mechanisms for the transmission of somatic symptoms from parents to children显示文摘AIM: To examine familial aggregation of irritable bowel syndrome(IBS) via parental reinforcement/modeling of symptoms, coping, psychological distress, and exposure to stress.METHODS:Mothers of children between the ages of8 and 15 years with and without IBS were identified through the Group Health Cooperative of Puget Sound.Mothers completed questionnaires,including the Child Behavior Checklist(child psychological distress),the Family Inventory of Life Events(family exposure to stress),SCL-90R(mother psychological distress),and the Pain Response Inventory(beliefs about pain).Children were interviewed separately from their parents and completed the Pain Beliefs Questionnaire(beliefs about pain),Pain Response Inventory(coping)and Child Symptom Checklist[gastrointestinal(GI)symptoms].In addition,health care utilization data was obtained from the automated database of Group Health Cooperative.Mothers with IBS(n=207)and their 296 children were compared to 240 control mothers and their 335 children,while controlling for age and education.RESULTS:Hypothesis 1:reinforcement of expression of GI problems is only related to GI symptoms,but not others(cold symptoms)in children.There was no significant correlation between parental reinforcement of symptoms and child expression of GI or other symptoms.Hypothesis 2:modeling of GI symptomsis related to GI but not non-GI symptom reporting in children.Children of parents with IBS reported more non-GI(8.97 vs 6.70,P<0.01)as well as more GI(3.24 vs 2.27,P<0.01)symptoms.Total health care visits made by the mother correlated with visits made by the child(rho=0.35,P<0.001 for cases,rho=0.26,P<0.001 for controls).Hypothesis 3:children learn to share the methods of coping with illness that their mothers exhibit.Methods used by children to cope with stomachaches differed from methods used by their mothers.Only 2/16 scales showed weak but significant correlations(stoicism rho=0.13,P<0.05;acceptance rho=0.13,P<0.05).Hypothesis 4:mothers and children share psychological traits such as anxiety,depression,and somatization.Child psychological distress correlated with mother’s psychological distress(rho=0.41,P<0.001 for cases,rho=0.38,P<0.001 for controls).Hypothesis 5:stress that affects the whole family might explain the similarities between mothers and their children.Family exposure to stress was not a significant predictor of children’s symptom reports.Hypothesis 6:the intergenerational transmission of GI illness behavior may be due to multiple mechanisms.Regression analysis identified multiple independent predictors of the child’s GI complaints,which were similar to the predictors of the child’s non-GI symptoms(mother’s IBS status,child psychological symptoms,child catastrophizing,and child age).CONCLUSION:Multiple factors influence the reporting of children’s gastrointestinal and non-gastrointestinal symptoms.The clustering of illness within families is best understood using a model that incorporates all these factors. | Miranda AL van Tilburg Rona L Levy Lynn S Walker Michael Von Korff Lauren D Feld Michelle Garner Andrew D Feld William E Whitehead | 2015 | World Journal of Gastroenterology2015，21，18： | 2 |
| 2 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004，101，26： | 1 |
| 3 | Effects of elevated CO2,nitrogen and phosphorus on the growth and photosynthesis of two upland perennials:Calluna vulgaris and Pteridium aquilinum显示文摘 | Whitehead S J Caporn S J M Press M C | 1997 | New Phytol1997，135，2： | 1 |
| 4 | Quorum sensing as a population-density-de- pendent determinant of bacterial physiology显示文摘 | SWIFT S D J WHITEHEAD N A BARNARD A M | 2001 | Med Microbiol Immunol2001，45，： | 1 |
| 5 | Persistent problemsof access to appropriate, affordable TB services in rural China: experiences of different socio-economic groups 显示文摘 | Zhang T Tang S Jun G Whitehead M | 2007 | BMC Pub- lic Health2007，7，： | 1 |
| 6 | Deciphering the biology of My cobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole S T Brosch R Parkhill J Gamier T Churcher C Harris D Gordon S V Eiglmeier K Gas S Barry C E Tekaia F Badcock K Basham D Brown D Chillingworth T Cormor R Davies R Devlin K FeltweU T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Kroghs A McLean J Moule S Murphy L Oliver K Osborne J Quail M A Rafandream M A Rogers J Rutter S Seeger K Skelton J Squaraes R Squares S Sulston J E Taylo K Whitehead S Barrell B G | 1998 | Nature1998，393，： | 1 |
| 7 | Vari- ations in REE and Sr-isotope chemistry of carbonate gangue, Castellanos Zn- Pb deposit, Cuba 显示文摘 | Davies J F Prevec S A Whitehead R E | 1998 | Chemical Geology1998，144，： | 1 |
| 8 | Silencing or stimulation? siRNA delivery and the immune system显示文摘 | Whitehead K A Dahlman J E Langer R S | 2011 | Annu Rev Chem Biomol Eng2011，2，： | 1 |
| 9 | Local expression of the serum amyloid A and formyl pepfide receptor-like 1 genes in synovial tissue is associated with matrix metalloproteinase production in patients with inflammatory arthritis显示文摘 | O'HABA R MURPHY E P WHITEHEAD A S | 2004 | Arthritis Rheum2004，50，6： | 1 |
| 10 | Insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced but not basal proliferation and adhesion of L1M 1215 colon cancer cells 显示文摘 | Leng S L Leeding K S Whitehead R H | 2001 | Molecular and Cellular Endocrinology2001，174，12： | 1 |
| 11 | Serum amyloid A,the major vertebrate acute-phase reactant 显示文摘 | UHLAR C M WHITEHEAD A S | 1999 | Eur J Biochem1999，265，2： | 1 |
| 12 | Assessment of damage tolerance in composites显示文摘 | Whitehead R S Deo R B | 1985 | Composite Structures1985，4，： | 1 |
| 13 | Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole ST Brosch R Parkhill J Garnier T Churcher C Harris D Gordon SV Eiglmeier K Gas S Barry CE Tekaia F Badcock K Basham D Brown D Chillingworth T Connor R Davies R Devlin K Feltwell T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Krogh A Mclean J Moule S Murphy L Oliver K Osborne J Quail MA Rajandream MA Rogers J Rutter S Seeger K Skelton J Squares R Squares S Sulston JE Taylor K Whitehead S Barrell BG | 1998 | Nature1998，393，6685： | 1 |
| 14 | Neuropilin1 directly interacts with Fer kinase to mediate semaphorin3A-induced death of cortical neurons显示文摘 | JIANG SX WHITEHEAD S AYLSWORTH A | 2010 | J Biol Chem2010，285，13： | 1 |
| 15 | Establishment of con- ditionally immortalized epithelial cell lines from the intestinal tissue of adult normal and transgenic mice显示文摘 | WHITEHEAD R H ROBINSON P S | 2009 | Am J Physiol Gastrointest Liver Physiol2009，296，3： | 1 |
| 16 | Evaluating the Economic Impact of Planning Controls in the United Kingdom:Some Implications for Housing显示文摘 | Monk S C M E Whitehead | 1999 | Land Economics1999，75，1： | 1 |
| 17 | Pyrolysis massspectrometry as a method for the classification, identification and selection of actinomyecetes显示文摘 | J J Whitehead D Saddler G S | 1992 | Gene1992，，115： | 1 |
| 18 | Willingness to pay for submerged maritime cultural resources 显示文摘 | Whitehead J C Finney S S | 2003 | Journal of Cultural Eco- nomics2003，27，： | 1 |
| 19 | Transient and bilateral increase in Neuropilin-1,Fer kinase and collapsin response mediator proteins within membrane rafts following unilateral occlusion of the middle cerebral artery in mouse显示文摘 | WHITEHEAD SN GANGARAJU S SLINN J | 2010 | Brain Res2010，1344，： | 1 |
| 20 | Epstein-Barr virus infection in paediatric liver transplant recipients:detection of the virus in post-transplant tonsillectomy specimens显示文摘 | Meru N Davison S Whitehead L | 2001 | Mol Pathol2001，54，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员