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| 1 | High-Chern-number and high-temperature quantum Hall effect without Landau levels显示文摘The quantum Hall effect(QHE)with quantized Hall resistance ofh/ve2 started the research on topological quantum states and laid the foundation of topology in physics.Since then,Haldane proposed the QHE without Landau levels,showing nonzero Chern number|C|=1,which has been experimentally observed at relatively low temperatures.For emerging physics and low-power-consumption electronics;the key issues are how to increase the working temperature and realize high Chern numbers(C>1).Here,we report the experimental discovery of high-Chern-number QHE(C=2)without Landau levels and C=1 Chern insulator state displaying a nearly quantized Hall resistance plateau above the Neel temperature in MnBi2Te4 devices.Our observations provide a new perspective on topological matter and open new avenues for exploration of exotic topological quantum states and topological phase transitions at higher temperatures. | Jun Ge Yanzhao Liu Jiaheng Li Hao Li Tianchuang Luo Yang Wu Yong Xu Jian Wang | 2020 | National Science Review2020，7，8： | 10 |
| 2 | In situ observation and thermodynamic calculation of MnS in 49MnVS3 non-quenched and tempered steel显示文摘Based on thermodynamics calculation, the results of the formation temperature of MnS inclusions of non-quenched and tempered steel during heating process were discussed. It is shown that while the solid fraction is 0.9, MnS inclusions began to precipitate in the final stage of solidification. The solidification process of 49MnVS3 non-quenched and tempered steel during heating has been observed in situ using a confocal scanning laser microscope (CSLM), which agrees well with the thermodynamics calculation. MnS particles were coarsening during heating process, which would reduce the pinning effect on the austenite grain boundaries and bring about the sudden growth of some austenite grains in this stage. | Yanzhao LUO Jiongming ZHANG Zhiming LIU ChaoXIAO Suzhou WU | 2011 | Acta Metallurgica Sinica(English Letters)2011，24，4： | 6 |
| 3 | Joint Allocation of Wireless Resource and Computing Capability in MEC-Enabled Vehicular Network显示文摘In MEC-enabled vehicular network with limited wireless resource and computation resource,stringent delay and high reliability requirements are challenging issues.In order to reduce the total delay in the network as well as ensure the reliability of Vehicular UE(VUE),a Joint Allocation of Wireless resource and MEC Computing resource(JAWC)algorithm is proposed.The JAWC algorithm includes two steps:V2X links clustering and MEC computation resource scheduling.In the V2X links clustering,a Spectral Radius based Interference Cancellation scheme(SR-IC)is proposed to obtain the optimal resource allocation matrix.By converting the calculation of SINR into the calculation of matrix maximum row sum,the accumulated interference of VUE can be constrained and the the SINR calculation complexity can be effectively reduced.In the MEC computation resource scheduling,by transforming the original optimization problem into a convex problem,the optimal task offloading proportion of VUE and MEC computation resource allocation can be obtained.The simulation further demonstrates that the JAWC algorithm can significantly reduce the total delay as well as ensure the communication reliability of VUE in the MEC-enabled vehicular network. | Yanzhao Hou Chengrui Wang Min Zhu Xiaodong Xu Xiaofeng Tao Xunchao Wu | 2021 | China Communications2021，18，6： | 4 |
| 4 | Optically stimulated luminescence dosimeter based on CaS:Eu,Sm显示文摘Alkaline earth sulfides (MgS,CaS and BaS) crystal doped with rare-earth ions is an optically stimulated luminescence dosimeter with very high sensitivity,short time constant of the optically stimulated luminescence (OSL) separated perfectly from the stimulation.In this paper,an OSL dosimeter is described.It has linear dose response from 0.01 to 1000 Gy.The equipment,relatively simple and small in size is promising for applications in space exploration and for high dose irradiation and dangerous irradiation conditions. | LIU Yanping CHEN Zhaoyang BA Weizhen FAN Yanwei GUO Qi YU Xuefeng CHANG Aiming LU Wu DU Yanzhao | 2008 | Nuclear Science and Techniques2008，19，2： | 4 |
| 5 | An enrichment model using regular health examination data for early detection of colorectal cancer显示文摘Objective: Challenges remain in current practices of colorectal cancer(CRC) screening, such as low compliance,low specificities and expensive cost. This study aimed to identify high-risk groups for CRC from the general population using regular health examination data.Methods: The study population consist of more than 7,000 CRC cases and more than 140,000 controls. Using regular health examination data, a model detecting CRC cases was derived by the classification and regression trees(CART) algorithm. Receiver operating characteristic(ROC) curve was applied to evaluate the performance of models. The robustness and generalization of the CART model were validated by independent datasets. In addition, the effectiveness of CART-based screening was compared with stool-based screening.Results: After data quality control, 4,647 CRC cases and 133,898 controls free of colorectal neoplasms were used for downstream analysis. The final CART model based on four biomarkers(age, albumin, hematocrit and percent lymphocytes) was constructed. In the test set, the area under ROC curve(AUC) of the CART model was 0.88 [95%confidence interval(95% CI), 0.87-0.90] for detecting CRC. At the cutoff yielding 99.0% specificity, this model’s sensitivity was 62.2%(95% CI, 58.1%-66.2%), thereby achieving a 63-fold enrichment of CRC cases. We validated the robustness of the method across subsets of test set with diverse CRC incidences, aging rates, genders ratio, distributions of tumor stages and locations, and data sources. Importantly, CART-based screening had the higher positive predictive value(1.6%) than fecal immunochemical test(0.3%).Conclusions: As an alternative approach for the early detection of CRC, this study provides a low-cost method using regular health examination data to identify high-risk individuals for CRC for further examinations. The approach can promote early detection of CRC especially in developing countries such as China, where annual health examination is popular but regular CRC-specific screening is rare. | Qiang Shi Zhaoya Gao Pengze Wu Fanxiu Heng Fuming Lei Yanzhao Wang Qingkun Gao Qingmin Zeng Pengfei Niu Cheng Li Jin Gu | 2019 | Chinese Journal of Cancer Research2019，31，4： | 3 |
| 6 | Optically tunable fluorescent carbon nanoparticles and their application in fluorometric sensing of copper ions显示文摘A series of carb on nano particles(CNPs)with emissi on wavele ngth ranging from 483 to 525 nm were prepared by hydrothermal treatme nt of poly-3-thiopheneacetic acid(PTA)and NaOH.The emission wavelength and surface oxidation degree of CNPs were shown to be controllable by simply adjusti ng NaOH concentration.These CNPs prese nted obvious fluoresce nee spectral response toward copper ions(Cu^2+)through static quenching caused synergistically by electron transfer and inner filter effect.The O-and S-containing groups on the surface of CNPs were dem on strated to be resp on sible for their outsta nding sensing performa nee.Based on that,a CN Ps-based ratiometric fluoresce nt probe for Cu^2+with a high fluoresce nee quenching rate constant of 1.4×10^5 L/mol and a short resp onse time(10 s)was developed.Their practical applications in detecting Cu^2+in pond water and living cells were also dem on strated. | Minhuan Lan Shaojing Zhao Shuilin Wu Xiaofang Wei Yanzhao Fu Juanjuan Wu Pengfei Wang Wenjun Zhang | 2019 | Nano Research2019，12，10： | 2 |
| 7 | Resistive switching and artificial synaptic performances of memristor based on low-dimensional bismuth halide perovskites显示文摘Zero-dimensional(0D)-Cs_(3)Bi_(2)I_(9),two-dimensional(2D)-Cs_(3)Bi_(2)Br_(9),and one-dimensional(1D)-Cs3Bi2Cl9 perovskite films have been successfully grown on indium tin oxide(ITO)glass substrates,which were used to fabricate memristors with the structure of Al/Cs_(3)Bi_(2)X_(9)(X=I,Br,and Cl)/ITO glass.The current three types of memristors exhibited bipolar resistive switching behaviors.Both the endurance and retention time tests clearly demonstrated the excellent stability of present devices.Especially,the ON/OFF ratio of the 0D-Cs_(3)Bi_(2)I_(9)device is close to 104 at the reading voltage of 0.1 V,which is nearly 100 and 1000 times larger than those of the 1D-Cs3Bi2Cl9 device and the 2D-Cs_(3)Bi_(2)Br_(9)device,respectively.The activation energy of halide vacancies in the Cs_(3)Bi_(2)X_(9)(X=I,Br,and Cl)films was calculated using the density functional theory by considering a minimum migration path,demonstrating the dimensionality of the Cs_(3)Bi_(2)X_(9)(X=I,Br,and Cl)film affected the formation and rupture of conductive filaments.Moreover,the short-term plasticity and long-term plasticity of biological synapse were simulated by evaluating the conductance responses of Al/Cs_(3)Bi_(2)X_(9)(X=I,Br,and Cl)/ITO devices under various voltage pulses in detail.The duration time of long-term plasticity in all the present devices can last for up to 250 s.The 0D-Cs_(3)Bi_(2)I_(9)device showed both the highest spikeduration-dependent plasticity and paired-pulse facilitation indexes compared to the other two devices.Additionally,the 0DCs_(3)Bi_(2)I_(9)device successfully established the associative learning behavior by simulating the Pavlov’s dog experiment. | Feifei Luo Yanzhao Wu Junwei Tong Fubo Tian Xianmin Zhang | 2023 | Nano Research2023，16，7： | 1 |
| 8 | A 13-bit, Low-power, compact ADC suitable for sensor applications 显示文摘 | Honglei Dong Wu Yanzhao Shen | 2010 | Circuits and Systems(ISCAS)2010，，： | 1 |
| 9 | Mesh model building and migration and accumulation simulation of 3D hydrocarbon carrier system显示文摘Migration and accumulation simulation of oil and gas in carrier systems has always been a difficult subject in the quantitative study of petroleum geology. In view of the fact that the traditional geological modeling technology can not establish the interrelation of carriers in three dimensional space, we have proposed a hybrid-dimensional mesh modeling technology consisting of body(stratum), surfaces(faults and unconformities), lines and points, which provides an important research method for the description of geometry of sand bodies, faults and unconformities, the 3 D geological modeling of complex tectonic areas, and the simulation of hydrocarbon migration and accumulation. Furthermore, we have advanced a 3 D hydrocarbon migration pathway tracking method based on the hybrid-dimensional mesh of the carrier system. The application of this technology in western Luliang Uplift of Junggar Basin shows that the technology can effectively characterize the transport effect of fault planes, unconformities and sand bodies, indicate the hydrocarbon migration pathways, simulate the process of oil accumulation, reservoir adjustment and secondary reservoir formation, predict the hydrocarbon distribution. It is found through the simulation that the areas around the paleo-oil reservoir and covered by migration pathways are favorable sites for oil and gas distribution. | GUO Qiulin LIU Jifeng CHEN Ningsheng WU Xiaozhi REN Hongjia WEI Yanzhao CHEN Gang GONG Deyu YUAN Xuanjun | 2018 | Petroleum Exploration and Development2018，45，6： | 0 |
| 10 | Optimization of Blade Geometry of Savonius Hydrokinetic Turbine Based onGenetic Algorithm显示文摘Savonius hydrokinetic turbine is a kind of turbine set which is suitable for low-velocity conditions.Unlike conventional turbines,Savonius turbines employ S-shaped blades and have simple internal structures.Therefore,there is a large space for optimizing the blade geometry.In this study,computational fluid dynamics(CFD)numerical simulation and genetic algorithm(GA)were used for the optimal design.The optimization strategies and methods were determined by comparing the results calculated by CFD with the experimental results.The weighted objective function was constructed with the maximum power coefficient Cp and the high-power coefficient range R under multiple working conditions.GA helps to find the optimal individual of the objective function.Compared the optimal scheme with the initial scheme,the overlap ratioβincreased from 0.2 to 0.202,and the clearance ratioεincreased from 0 to 0.179,the blade circumferential angleγincreased from 0°to 27°,the blade shape extended more towards the spindle.The overall power of Savonius turbines was maintained at a high level over 22%,R also increased from 0.73 to 1.02.In comparison with the initial scheme,the energy loss of the optimal scheme at high blade tip speed is greatly reduced,and this reduction is closely related to the optimization of blade geometry.As R becomes larger,Savonius turbines can adapt to the overall working conditions and meet the needs of its work in low flow rate conditions.The results of this paper can be used as a reference for the hydrodynamic optimization of Savonius turbine runners. | Jiahao Lu Fangfang Zhang Weilong Guang Yanzhao Wu Ran Tao Xiaoqin Li Ruofu Xiao | 2023 | Energy Engineering2023，120，12： | 0 |
| 11 | The divergence of brassinosteroid sensitivity between rice subspecies involves natural variation conferring altered internal auto-binding of OsBSK2显示文摘Japonica/geng and indica/xian are two major rice(Oryza sativa)subspecies with multiple divergent traits,but how these traits are related and interact within each subspecies remains elusive.Brassinosteroids(BRs)are a class of steroid phytohormones that modulate many important agronomic traits in rice.Here,using different physiological assays,we revealed that japonica rice exhibits an overall lower BR sensitivity than indica.Extensive screening of BR signaling genes led to the identification of a set of genes distributed throughout the primary BR signaling pathway with divergent polymorphisms.Among these,we demonstrate that the C38/T variant in BR Signaling Kinase2(OsBSK2),causing the amino acid change P13L,plays a central role in mediating differential BR signaling in japonica and indica rice.OsBSK2in indica plays a greater role in BR signaling than OsB SK2in japonica by affecting the auto-binding and protein accumulation of OsBSK2.Finally,we determined that OsBSK2 is involved in a number of divergent traits in japonica relative to indica rice,including grain shape,tiller number,cold adaptation,and nitrogen-use efficiency.Our study suggests that the natural variation in OsB SK2 plays a key role in the divergence of BR signaling,which underlies multiple divergent traits between japonica and indica. | Wenchao Yin Lulu Li Zhikun Yu Fan Zhang Dapu Liu Hongkai Wu Mei Niu Wenjing Meng Xiaoxing Zhang Nana Dong Yanzhao Yang Jihong Liu Yongqiang Liu Guoxia Zhang Jianlong Xu Shimei Wang Chengcai Chu Qian Qian Hongning Tong | 2022 | Journal of Integrative Plant Biology2022，64，8： | 0 |
| 12 | Electrically manipulating magnetization reversal via energy band engineering显示文摘Realization of a magnetization reversal by an external electric field is vital for developing ultra-low-power spintronic devices.In this report,starting from energy band engineering,a general design principle is proposed for achieving electrical manipulation of a nonvolatile 180°magnetization reversal.A half semiconductor(HSC)and a bipolar magnetic semiconductor(BMS)are selected as the model of magnetic layers,whose conduction-band minimum and valence-band maximum are in the same and opposite spin states,respectively.Based on the analysis of virtual hopping and tight-binding models,the interlayer coupling of HSC/insulator/BMS devices is successfully tuned between ferromagnetic and antiferromagnetic interactions by varying electric field directions.Moreover,the interlayer coupling nearly disappears after removing the electric field,proving the nonvolatile magnetization reversal.Using first-principles calculations,the feasibility of present design strategy is further confirmed by a representative device with the structure of CrBr3/h-BN/2H-VSe_(2).This design guideline and physical phenomena may open an avenue to explore magnetoelectric coupling mechanisms and develop next-generation spintronic devices. | Junwei Tong Yanzhao Wu Feifei Luo Fubo Tian Xianmin Zhang | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，5： | 0 |
| 13 | Size-transformable nanoparticles with sequentially triggered drug release and enhanced penetration for anticancer therapy显示文摘There are several limitations to the application of nanoparticles in the treatment of cancer,including their low drug loading,poor colloidal stability,insufficient tumor penetration,and uncontrolled release of the drug.Herein,gelatin/laponite(LP)/doxorubicin(GLD)nanoparticles are developed by crosslinking LP with gelatin for doxorubicin delivery.GLD shows high doxorubicin encapsulation efficacy(99%)and strong colloidal stability,as seen from the unchanged size over the past 21 days and reduced protein absorption by 48-fold compared with unmodified laponite/doxorubicin nanoparticles.When gelatin from 115 nm GLD reaches the tumor site,matrix metallopeptidase-2(MMP-2)from the tumor environment breaks it down to release smaller 40 nm LP nanoparticles for effective tumor cell endocytosis.As demonstrated by superior penetration in both in vitro three-dimensional(3D)tumor spheroids(138-fold increase compared to the free drug)and in vivo tumor models.The intracellular low pH and MMP-2 further cause doxorubicin release after endocytosis by tumor cells,leading to a higher inhibitory potential against cancer cells.The improved anticancer effectiveness and strong in vivo biocompatibility of GLD have been confirmed using a mouse tumor-bearing model.MMP-2/pH sequentially triggered anticancer drug delivery is made possible by the logical design of tumor-penetrating GLD,offering a useful method for anticancer therapy. | Yulin Li Liudi Wang Guoqiang Zhong Guoying Wang Yanzhao Zhu Jian Li Lan Xiao Yanhui Chu Yan Wu Kaichun Li Jie Gao | 2023 | Nano Research2023，16，8： | 0 |
| 14 | High-efficiency resistive switch and artificial synaptic simulation in antimony-based perovskite devices显示文摘Three kinds of Cs_(3)Sb_(2)X_(9)(X=I,Br,Cl)perovskite films have been prepared to fabricate the resistive memory devices with the structure of Al/Cs_(3)Sb_(2)X_(9)(X=I,Br,Cl)/indium tin oxide(ITO)glass.All devices exhibited a bipolar resistive switching behavior at room temperature by applying scanning voltage of 0→1→0→-1.8→0 V.The switching voltages in the Al/Cs_(3)Sb_(2)X_(9)(X=I,Br,Cl)/ITO devices gradually decreased with the X from I,Br to Cl due to the different migration rates of halide vacancy in perovskite films,which is confirmed by the first-principles calculations of activation energy.The ON/OFF ratio under the reading voltage of 0.1 V significantly increased up to 100 in the Al/Cs_(3)Sb_(2)Cl_(9)/ITO device,which is nearly 10 and 3 times larger than that of the Al/Cs3Sb2I9/ITO device and the Al/Cs_(3)Sb_(2)Br_(9)/ITO device,respectively.The endurance cycles and retention time of current devices were evaluated,showing the excellent electrical stability.Importantly,the three kinds of Al/Cs_(3)Sb_(2)X_(9)(X=I,Br,Cl)/ITO device can successfully simulate the short-term plasticity of biological synapse.The Al/Cs_(3)Sb_(2)Cl_(9)/ITO device showed the highest paired-pulsed facilitation index compared with that of other two devices,which was explored for the longterm plasticity and learning experience processes of synapse.In addition,the Al/Cs_(3)Sb_(2)Cl_(9)/ITO device established associative learning behavior by simulating the Pavlov’s dog experiment. | LUO FeiFei WU YanZhao TONG JunWei XU DaKe QIN GaoWu TIAN FuBo ZHANG XianMin | 2023 | Science China(Technological Sciences)2023，66，4： | 0 |
| 15 | Flexible radio-frequency micro electro-mechanical switch towards the applications of satellite communications显示文摘This paper presents a flexible radio-frequency microelectromechanical system(RF MEMS)switch integrated on cyclo-olefin polymer(COP)substrate using a modified surface MEMS processing technology,which could be used in the 17-19 GHz frequency band of satellite communication.Through systematic simulation analysis,it is found that flexible RF MEMS switch can achieve certain bending radius by miniaturizing the electronic dimension,without degrading the RF performance.It is demonstrated that the RF characteristics of flexible RF MEMS switch with special anchor structural design,fabricated by modified surface MEMS processing,are not sensitive to bending deformation under the curvature of 0 mm^(-1),0.05 mm^(-1),0.10 mm^(-1).Furthermore,the range of bending curvature which will affect the RF characteristics is given through systematic simulation.The flexible RF MEMS switch with high process compatibility and stable RF performance is believed to be promising candidates for future microwave communications and other consumer electronics. | Yingli Shi Chao Zhou Zibo Cao Yurong He Jingwen Guo Chunxin Li Qianhong Wu Kui Liang Yanzhao Li Yuan Lin | 2022 | npj Flexible Electronics2022，6，1： | 0 |
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