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2篇 您的检索式:作者名="Wang Xiangyao"
    题名 作者 年代 出处 被引量
1A New Cultivation-Evolution Technology of Accident Immune Function for a Petrochemical Enterprise显示文摘为在一家石油化学的企业在生产事故上开发一个有免疫力的函数的目的,预防机制的一条新耕作进化途径被分析关于有免疫力的缺乏症候群的各种各样的因素建议,由指免疫,基因算法和相关概念在药science.Accident免疫系统申请了高度危险的石油化学的企业,它由它的生产系统的安全 Organand 安全组织组成,典型地是为有免疫力的功能的进化耕作进步,新 Bimmune 房间在几层的家以后被产生屏蔽,克隆膨胀, receptored iting ,在石油化学的企业在工作事故的免疫系统组织。有有高本能的一个 B 有免疫力的房间,一个功利性的函数作为解决方案作为目标函数和有免疫力的抗体在工业为 accident-immunity.Taking 锁住事故的抗原,作者 scarried 外面为在抗原和抗体之间的本能的预言的一张计算图。Yang Zhenhong Zhang Xuhua Wang Xiangyao Wang Zhihu Liu Yank Zhang Xuan 2007China Petroleum Processing & Petrochemical Technology2007,9,1:3
2Cux1^(+)proliferative basal cells promote epidermal hyperplasia in chronic dry skin disease identified by single-cell RNA transcriptomics显示文摘Pathological dry skin is a disturbing and intractable healthcare burden,characterized by epithelial hyperplasia and severe itch.Atopic dermatitis(AD)and psoriasis models with complications of dry skin have been studied using single-cell RNA sequencing(scRNA-seq).However,scRNA-seq analysis of the dry skin mouse model(acetone/ether/water(AEW)-treated model)is still lacking.Here,we used scRNA-seq and in situ hybridization to identify a novel proliferative basal cell(PBC)state that exclusively expresses transcription factor CUT-like homeobox 1(Cux1).Further in vitro study demonstrated that Cux1 is vital for keratinocyte proliferation by regulating a series of cyclin-dependent kinases(CDKs)and cyclins.Clinically,Cux1+PBCs were increased in patients with psoriasis,suggesting that Cux1+PBCs play an important part in epidermal hyperplasia.This study presents a systematic knowledge of the transcriptomic changes in a chronic dry skin mouse model,as well as a potential therapeutic target against dry skin-related dermatoses.Minhua Huang Ning Hua Siyi Zhuang Qiuyuan Fang Jiangming Shang Zhen Wang Xiaohua Tao Jianguo Niu Xiangyao Li Peilin Yu Wei Yang 2023Journal of Pharmaceutical Analysis2023,13,7:0
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