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| 1 | TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling显示文摘Osteoporosis is an osteolytic disorder commonly associated with excessive osteoclast formation.Transcriptional coactivator with PDZ-binding motif(TAZ)is a key downstream effector of the Hippo signaling pathway;it was suggested to be involved in the regulation of bone homeostasis.However,the exact role of TAZ in osteoclasts has not yet been established.In this study,we demonstrated that global knockout and osteoclast-specific knockout of TAZ led to a low-bone mass phenotype due to elevated osteoclast formation,which was further evidenced by in vitro osteoclast formation assays.Moreover,the overexpression of TAZ inhibited RANKL-induced osteoclast formation,whereas silencing of TAZ reduced it.Mechanistically,TAZ bound to TGF-activated kinase 1(TAK1)and reciprocally inhibited NF-κB signaling,suppressing osteoclast differentiation.Collectively,our findings highlight an essential role of TAZ in the regulation of osteoclastogenesis in osteoporosis and its underlying mechanism. | Wanlei Yang Xuanyuan Lu Tan Zhang Weiqi Han Jianlei Li Wei He Yewei Jia Kangxian Zhao An Qin Yu Qian | 2021 | Bone Research2021,9,3: | 6 |
| 2 | Security and privacy in 6G networks:New areas and new challenges显示文摘With the deployment of more and more 5g networks,the limitations of 5g networks have been found,which undoubtedly promotes the exploratory research of 6G networks as the next generation solutions.These investigations include the fundamental security and privacy problems associated with 6G technologies.Therefore,in order to consolidate and solidify this foundational research as a basis for future investigations,we have prepared a survey on the status quo of 6G security and privacy.The survey begins with a historical review of previous networking technologies and how they have informed the current trends in 6G networking.We then discuss four key aspects of 6G networks–real-time intelligent edge computing,distributed artificial intelligence,intelligent radio,and 3D intercoms–and some promising emerging technologies in each area,along with the relevant security and privacy issues.The survey concludes with a report on the potential use of 6G.Some of the references used in this paper along and further details of several points raised can be found at:security-privacyin5g-6g.github.io. | Minghao Wang Tianqing Zhu Tao Zhang Jun Zhang Shui Yu Wanlei Zhou | 2020 | Digital Communications and Networks2020,6,3: | 2 |
| 3 | Trust Mechanisms in Wireless Sen-sor Networks: Attack analysis and countermeasures 显示文摘 | Yu Y Keqiu L Wanlei Z | 2011 | Journal of Network and Computer Applications2011,,: | 1 |
| 4 | Self-Adaptive Clock Synchronization for Computational Grid 显示文摘 | Ying Zhao Wanlei Zhou | 2003 | Journal of Computer Science and Technology (S1000-9000)2003,18,4: | 1 |
| 5 | Network and system security 显示文摘 | Zhou Wanlei Yang Xiang | 2009 | Journal of Network and Computer Applications2009,32,2: | 1 |
| 6 | Trustmechanisms in wireless sensor networks:Attack analysis andcountermeasures显示文摘 | YU Yanli LI Keqiu ZHOU Wanlei | 2012 | Network and Computer Applications2012,35,3: | 1 |
| 7 | Secure own- ership transfer for multi-tag multi-owner passive RFID en- vironment with individual-owner-privacy 显示文摘 | Sundaresan S Doss R Zhou Wanlei | 2015 | Computer Communications2015,55,: | 1 |
| 8 | Trust Mechanisms in Wireless Sensor Networks: Attack Analysis and Countermeasures 显示文摘 | Yu Yanli Li Keqiu Zhou Wanlei | 2012 | Journal of Network and Computer Applications2012,35,3: | 1 |
| 9 | Generating Regular Expression Signatures for Network Traffic Classification in Trusted Net- work Management显示文摘 | WANG Yu XNG Yang ZHOU Wanlei et el | 2012 | Journal of Network and Computer Applications2012,35,3: | 1 |
| 10 | Traceback of DDo S attacks using entropy variations显示文摘 | Yu Shui Zhou Wanlei Doss R | 2011 | IEEE Transactions on Parallel and Distributed Systems2011,22,3: | 1 |
| 11 | On the annota- tion of Web videos by efficient near-duplicate search 显示文摘 | Zhao Wanlei Wu Xiao Ngo Chong-Wah | 2010 | IEEE Transactions on Multimedia2010,12,5: | 1 |
| 12 | Information theory based detection against network behavior mimicking DDoS attacks显示文摘 | YU SHUI ZHOU WANLEI | 2008 | Communications Letters2008,12,4: | 1 |
| 13 | Secure RFID tag owner- ship transfer based on quadratic residues显示文摘 | Doss R Zhou Wanlei Yu Shui | 2013 | IEEE Trans- actions on Information Forensics & Security2013,8,2: | 1 |
| 14 | Chaos Theory Based DetectionAgainst Network Mimicking DDoS Attacks显示文摘 | Chonka A Singh J Zhou Wanlei | 2009 | IEEE Commu-nications Letters2009,13,9: | 1 |
| 15 | A practical quadratic residues based scheme forauthentication and privacy in mobile RFID sys- tems显示文摘 | Robin D Saravanan S Wanlei Z | 2013 | Ad Hoc Networks2013,11,1: | 1 |
| 16 | Discriminating DDOS attacks from flash crowds using flow correlation coefficient显示文摘 | Yu Shui Zhou Wanlei Jia Weijia | 2012 | IEEE Transactions on Parallel and Distributed Systems2012,23,6: | 1 |
| 17 | On the annotation of web videos by efficient near-duplicate search 显示文摘 | ZHAO Wanlei WU Xiao NGO C W | 2010 | IEEE Transactions on Multimedia2010,12,5: | 1 |
| 18 | Secure RFID tag ownership transfer based on quadratic residues显示文摘 | Doss R Zhou Wanlei Yu Shui | 2013 | IEEE Trans on Information Forensics and Security2013,8,2: | 1 |
| 19 | Low-Rate DDoS Attacks Detection and Traceback by Using New Information Metrics, Information Foren- sics and Security显示文摘 | Yang Xiang Ke Li Wanlei Zhou | 2011 | IEEE Transactions on on page(s)2011,6,2: | 1 |
| 20 | Cloud security defence to protect cloud computing against HTTP-DoS and XML-DoS attacks显示文摘 | Ashley Chonka Yang Xiang Wanlei Zhou Alessio Bonti | 2010 | Journal of Network and Computer Applications2010,,4: | 1 |