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| 1 | Insights into the subunit in-teractions of the chloroplast ATP synthase显示文摘Subunit interactions of the chloroplast F0F1-ATP synthase were studied using the yeast two-hybrid sys-tem. The coding sequences of all the nine subunits of spinach chloroplast ATP synthase were cloned in two-hybrid vectors. The vectors were transformed into the yeast strains HF7c and SFY526 by various pairwise combinations, and the protein interactions were analyzed by measuring the yeast growth on minimal SD medium without serine, lucine and histidine. Interactions of γ subunit with wild type or two truncated mutants of ε sununit, ε△N21 and ε△C45, which lose their abilities to inhibit the ATP hydrolysis, were also detected by in vitro and in vivo binding assay. The present results are largely accordant to the common structure model of F0F1-ATP synthase. Different from that in the E. coli F0F1-ATP synthase, the δ subunit of chloroplast ATP synthase could interact with β. γ, ε and all the CF0 subunits in the two-hybrid system. These results suggested that though the chloroplast ATP synthase | Shi, XB Wei, JM Shen, YG | 2002 | Chinese Science Bulletin2002，47，1： | 3 |
| 2 | Maximum standardized uptake value on PET/CT in preoperative assessment of lymph node metastasis from thoracic esophageal squamous cell carcinoma显示文摘The presence of lymph node metastasis is an important prognostic factor for patients with esophageal cancer.Accurate assessment of lymph nodes in thoracic esophageal carcinoma is essential for selecting appropriate treatment and forecasting disease progression.Positron emission tomography combined with computed tomography(PET/CT)is becoming an important tool in the workup of esophageal carcinoma.Here,we evaluated the effectiveness of the maximum standardized uptake value(SUVmax)in assessing lymph node metastasis in esophageal squamous cell carcinoma(ESCC)prior to surgery.Fifty-nine surgical patients with pathologically confirmed thoracic ESCC were retrospectively studied.These patients underwent radical esophagectomy with pathologic evaluation of lymph nodes.They all had18F-FDG PET/CT scans in their preoperative staging procedures.None had a prior history of cancer.The pathologic status and PET/CT SUVmax of lymph nodes were collected to calculate the receiver operating characteristic(ROC)curve and to determine the best cutoff value of the PET/CT SUVmax to distinguish benign from malignant lymph nodes.Lymph node data from 27 others were used for the validation.A total of 323 lymph nodes including 39 metastatic lymph nodes were evaluated in the training cohort,and 117lymph nodes including 32 metastatic lymph nodes were evaluated in the validation cohort.The cutoff point of the SUVmax for lymph nodes was 4.1,as calculated by ROC curve(sensitivity,80%;specificity,92%;accuracy,90%).When this cutoff value was applied to the validation cohort,a sensitivity,a specificity,and an accuracy of 81%,88%,and 86%,respectively,were obtained.These results suggest that the SUVmax of lymph nodes predicts malignancy.Indeed,when an SUVmax of 4.1 was used instead of 2.5,FDG-PET/CT was more accurate in assessing nodal metastasis. | Amos JM Ela Bella Ya-Rui Zhang Wei Fan Kong-Jia Luo Tie-Hua Rong Peng Lin Hong Yang Jian-Hua Fu | 2014 | Chinese Journal of Cancer2014，33，4： | 3 |
| 3 | Clq/TNF-related protein-3 (CTRP3), a novel adipokine that regulates hepeatic glucose output显示文摘 | Peterson JM Wei Z Wong GW | 2010 | J Biol Chem2010，285，39： | 1 |
| 4 | Penetrating cardiac wounds: principles for surgical management 显示文摘 | Gao JM Gao YH Wei GB | 2004 | World J Surg2004，28，10： | 1 |
| 5 | Trends in specific immunotherapy for allergic rhinitis: A survey of Chinese ENT specialists显示文摘 | Zhou H Tao QL Wei JM | 2014 | Al- lergy Asthma Immunol Res2014，6，4： | 1 |
| 6 | Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase-2(COX-2) expression and inhibited by a COX-2-selectine inhibitor,etodolac显示文摘 | Chen WS Wei SJ Liu JM | 2001 | Int J Cancer2001，91，6： | 1 |
| 7 | Antibody neutralization and escape by HIV-1 显示文摘 | Wei X Decker JM Wang S | 2003 | Nature2003，422，6929： | 1 |
| 8 | The Age-Related Changes in Cartilage and Osteoarthritis显示文摘 | Li YP Wei XC Zhou JM | 2013 | BioMed Research Inter- national2013，9，16： | 1 |
| 9 | The is oflavone genistein : A new agent in dermatology? 显示文摘 | Wei H Spencer J Gelfand JM | 2001 | Cosmetic Dermatology2001，14，： | 1 |
| 10 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010，330，6010： | 1 |
| 11 | C1q/TNF-related protein-3(CTRP3),a novel adipokine that regulates hepatic glucose output显示文摘 | Peterson JM Wei Z Wong GW | 2010 | J Biol Chem2010，285，39： | 1 |
| 12 | Mitochondrial apoptosis and FAK signaling disruption by a novel histone deacety- lase inhibitor, HTPB, in antitumor and antimetastatic mouse models显示文摘 | Shieh JM Wei Tl' Tang YA | 2012 | PLOS One2012，7，30： | 1 |
| 13 | Penetrating cardiac wounds:principles for surgical management 显示文摘 | Gao JM Gao YH Wei GB | 2004 | World J Surg2004，28，10： | 1 |
| 14 | Changes in neocortical and hippocampal GABAA receptor subunit distribution during brain maturation and aging显示文摘 | Yu ZhiYuan Wang Wei Fritschy JM | | 0，，01： | 1 |
| 15 | Sodium phenylacetate ( NaPa ) improves the TAM effect on glioblastoma experimental tumors by inducing cell growth arrest and apoptosis 显示文摘 | Wei MX Liu JM Gadal F | 2007 | Anticancer Res2007，27，2： | 1 |
| 16 | Furosemide and the progression of left ventricular dysfunction in experimental heart failure显示文摘 | Mccurley JM Hanlon SU Wei SK | 2004 | J Am Coll Cardiol2004，44，： | 1 |
| 17 | Disruption of the cyclinD/cyclindependentkinase/INK4/retinoblastoma protein regulatory pathway in human neuroblastoma显示文摘 | Easton J Wei T Lahti JM | 1998 | Cancer Res1998，58，12： | 1 |
| 18 | Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor(T-20) monotherapy显示文摘 | WEI X DECKER JM LIU H | 2002 | Antimicrob Agents Chemother2002，46，6： | 1 |
| 19 | Risk factors for unexplained recurrent SpOntaneous abortion in a population from southern China显示文摘 | Zhang BY Wei YS Niu JM | 2010 | International Journal of Gynecology & Obstetrics2010，108，2： | 1 |
| 20 | Antibody neutralization and escape by HIV-I显示文摘 | Wei X Decker JM Wang S | 2003 | Nature2003，422，6929： | 1 |
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