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| 1 | H2A.Z Represses Gene Expression by Modulating Promoter Nucleosome Structure and Enhancer Histone Modifications in Arabidopsis显示文摘 | Xiaozhuan Dai Youhuang Bai Lihua Zhao Xianying DOU Yanhui Liu Lulu Wang Yi Li Weimin Li Yanan Hui Xinyu Huang Zonghua Wang Yuan Qin | 2017 | Molecular Plant2017，10，10： | 14 |
| 2 | On Uplink Non-Orthogonal Multiple Access for 5G:Opportunities and Challenges显示文摘In this paper,the concept of grantfree non-orthogonal multiple access(NOMA) for uplink data transmission is elaborated.NOMA in combination with grant-free can be applied to ultra reliability low latency communication(URLLC),massive machine type communication(m MTC),enhanced mobile broadband(e MBB) small packet and two-step random-access channel(RACH) scenarios.The advantages of grant-free NOMA are low latency and signaling overhead,high access capability and efficient resource utilization.Candidate uplink NOMA schemes are summarized and preliminary comparison among a subset of schemes are presented.Furthermore,design aspects for grant-free NOMA are discussed,with special notes on particular issues such as blind UE identification and transmitter/receiver(Tx/Rx) impairments in realistic deployment. | Li Tian Chunlin Yan Weimin Li Zhifeng Yuan Wei Cao Yifei Yuan | 2017 | China Communications2017，14，12： | 9 |
| 3 | Tribological Behavior of Al CoCrFeNi(Ti_(0.5))High Entropy Alloys under Oil and MACs Lubrication显示文摘The tribological properties of AlCoCrFeNi and AlCoCrFeNiTi_(0.5) high entropy alloys under gear oil and multiply alkylated cyclopentanes(MACs)lubrication condition have been studied.The equiaxed crystal structure of AlCoCrFeNi alloy is obtained after heat-treatment.The AlCoCrFeNiTi_(0.5) alloy keeps dendrite structure.Under the gear oil with good lubrication action,AlCoCrFeNiTi_(0.5) alloy preserves better tribological properties than AlCoCrFeNi alloy.The delamination and crack behaviors tend to occur in the grain boundary of AlCoCrFeNi alloy and along the interdendrite region of AlCoCrFeNiTi_(0.5) alloy.Under the MACs with relatively poor lubrication action,the applied load slightly influences the wear behavior of AlCoCrFeNi alloy,but seriously impacts the wear mechanism of AlCoCrFeNiTi_(0.5) alloy.Compared with AlCoCrFeNi alloy,AlCoCrFeNiTi_(0.5) alloy keeps better wear-resistance at low applied load of 100 N,but preserves less wearresistance at high applied load of 200 N. | Yuan Yu Jun Wang Jinshan Li Jun Yang Hongchao Kou Weimin Liu | 2016 | Journal of Materials Science & Technology2016，32，5： | 6 |
| 4 | Mapping the immune microenvironment for mandibular alveolar bone homeostasis at single-cell resolution显示文摘Alveolar bone is the thickened ridge of jaw bone that supports teeth.It is subject to constant occlusal force and pathogens invasion,and is therefore under active bone remodeling and immunomodulation.Alveolar bone holds a distinct niche from long bone considering their different developmental origin and postnatal remodeling pattern.However,a systematic explanation of alveolar bone at single-cell level is still lacking.Here,we construct a single-cell atlas of mouse mandibular alveolar bone through single-cell RNA sequencing(scRNA-seq).A more active immune microenvironment is identified in alveolar bone,with a higher proportion of mature immune cells than in long bone.Among all immune cell populations,the monocyte/macrophage subpopulation most actively interacts with mesenchymal stem cells(MSCs)subpopulation.Alveolar bone monocytes/macrophages express a higher level of Oncostatin M(Osm)compared to long bone,which promotes osteogenic differentiation and inhibits adipogenic differentiation of MSCs.In summary,our study reveals a unique immune microenvironment of alveolar bone,which may provide a more precise immune-modulatory target for therapeutic treatment of oral diseases. | Weimin Lin Qiwen Li Danting Zhang Xiaohan Zhang Xingying Qi Qian Wang Yaqian Chen Caojie Liu Hanwen Li Shiwen Zhang Yuan Wang Bin Shao Li Zhang Quan Yuan | 2021 | Bone Research2021，9，1： | 6 |
| 5 | 3D Particle Image Velocimetry Test of Inner Flow in a Double Blade Pump Impeller显示文摘The double blade pump is widely used in sewage treatment industry,however,the research on the internal flow characteristics of the double blade pump with particle image velocimetry(PIV) technology is very little at present.To reveal inner flow characteristics in double blade pump impeller under off-design and design conditions,inner flows in a double blade pump impeller,whose specific speed is 111,are measured under the five off-design conditions and design condition by using 3D PIV test technology.In order to ensure the accuracy of the 3D PIV test,the external trigger synchronization system which makes use of fiber optic and equivalent calibration method are applied.The 3D PIV relative velocity synthesis procedure is compiled by using Visual C++ 2005.Then absolute velocity distribution and relative velocity distribution in the double blade pump impeller are obtained.Test results show that vortex exists in each condition,but the location,size and velocity of vortex core are different.Average absolute velocity value of impeller outlet increases at first,then decreases,and then increases again with increase of flow rate.Again average relative velocity values under 0.4,0.8,and 1.2 design condition are higher than that under 1.0 design condition,while under 0.6 and 1.4 design condition it is lower.Under low flow rate conditions,radial vectors of absolute velocities at impeller outlet and blade inlet near the pump shaft decrease with increase of flow rate,while that of relative velocities at the suction side near the pump shaft decreases.Radial vectors of absolute velocities and relative velocities change slightly under the two large flow rate conditions.The research results can be applied to instruct the hydraulic optimization design of double blade pumps. | LIU Houlin WANG Kai YUAN Shouqi TAN Minggao WANG Yong RU Weimin | 2012 | Chinese Journal of Mechanical Engineering2012，25，3： | 5 |
| 6 | Study of algorithms of phase advance measurement between BPMs and its application in SSRF显示文摘As a third generation light source, Shanghai Synchrotron Radiation Facility (SSRF) has up to 140 beam position monitors (BPM) installed to monitor the beam dynamics on its storage ring. Once the operation mode is chosen, the betatron functions are determined. Since the sinusoidal betatron oscillation is the dominant component of the transverse motion, these BPMs can be used to measure the motion to get the betatron functions. Three methods are compared to calculate the phase advance among the BPMs in this paper, aiming to find one or more feasible ways to check the beam optics in SSRF. Some experiments have also been made to verify the practicality of the phase information. | CHEN Zhichu LENG Yongbin YUAN Renxian YAN Yingbing ZHOU Weimin | 2013 | Nuclear Science and Techniques2013，24，1： | 4 |
| 7 | Preliminary observation results of the Coherent Beacon Systemonboard the China Seismo-Electromagnetic Satellite-1显示文摘This paper reports, for the first time, observation results of the Coherent Beacon System(CBS) onboard the China SeismoElectromagnetic Satellite-1(CSES-1). We describe the CBS, and the Computerized Ionospheric Tomography(CIT) algorithm program is validated by numerical experiment. Two examples are shown, for daytime and nighttime respectively. The Equatorial Ionization Anomaly(EIA) can be seen, and the northern crest core is located at ~20°N in the reconstruction image at 07:28 UTC on 20 July 2018(daytime).Disturbances are shown in the reconstruction image at 18:40 UTC on 13 July 2018(nighttime). We find that beacon measurements are more consistent with ionosonde measurements than model results, by comparing Nm F2 at three sites at Lanzhou, Chongqing, and Kunming; consistency with ionosonde measurements validates beacon measurements. Finally, we have studied Vertical Total Electron Content(VTEC) variations from ground to ~500 km(the height of CSES-1 orbit) and ratios of VTEC between beacon measurements and CODE(Center for Orbit Determination in Europe) data. VTEC variation from ground to ~500 km has a range of 7.2–16.5 TECU for the daytime case and a range of 1.1–1.7 TECU for the nighttime case. The Beacon/CODE ratio of VTEC varies with latitude and time. The mean Beacon/CODE ratio is 0.69 for the daytime case and 0.26 for the nighttime case. The fact that the nighttime case yields lower ratios indicates the higher altitude of the ionosphere during nighttime when the ionosphere is assumed to be a thin layer. | Liang Chen Ming Ou YaPing Yuan Fang Sun Xiao Yu WeiMin Zhen | 2018 | Earth and Planetary Physics2018，2，6： | 3 |
| 8 | Design and measurement of signal processing system for cavity beam position monitor显示文摘In this paper,in order to achieve the output signal processing of cavity beam position monitor(CBPM),we develop a digital intermediate frequency receiver architecture based signal processing system,which consists of radio frequency(RF) front end and high speed data acquisition board.The beam position resolution in the CBPM signal processing system is superior to 1μm.Two signal processing algorithms,fast Fourier transform(FFT) and digital down converter(DDC),are evaluated offline using MATLAB platform,and both can be used to achieve,the CW input signal,position resolutions of 0.31μm and 0.10μm at -16 dBm.The DDC algorithm for its good compatibility is downloaded into the FPGA to realize online measurement,reaching the position resolution of 0.49μm due to truncation error.The whole system works well and the performance meets design target. | WANG Baopeng LENG Yongbin YU Luyang ZHOU Weimin YUAN Renxian CHEN Zhichu | 2013 | Nuclear Science and Techniques2013，24，2： | 3 |
| 9 | Combined effects of interface modification and micro-filler reinforcements on the thermal and tribological performances of fabric composites显示文摘The high specific‐strength of glass fibers and exceptional self‐lubrication of polytetrafluoroethylene(PTFE)fibers promote the potential application of hybrid PTFE/glass fabric composites in the tribological field,but their weak interfacial adhesion and inferior thermal properties significantly inhibit their tribological performance and reliability.Herein,a hybrid of polydopamine/silicon carbide/polyethyleneimine(PDA/SiC/PEI)functional coating was co‐deposited onto the hybrid PTFE/glass fabric surface through a one‐step impregnation method,leading to increased surface roughness and abundant amine groups.Tensile and peeling tests showed that this functional coating offered 47.8%enhancement in the fabric/matrix interfacial adhesion without compromising the strength of the pristine fabric.Moreover,the additional incorporation of WS_(2),and aluminum nitride(AlN)micro‐fillers contributed to the development of a high‐quality tribofilm and improved the thermal properties of fabric composites.The results of wear tests proved that the hybrid‐fabric composites,after the introduction of functional coating and micro‐fillers,exhibited outstanding tribological performance,which was attributed to the superior interfacial adhesion as well as the synergistic enhancement effects between WS2 and AlN micro‐fillers. | Junya YUAN Zhaozhu ZHANG Mingming YANG Xin ZHAO Liangfei WU Peilong LI Wei JIANG Xuehu MEN Weimin LIU | 2021 | Friction2021，9，5： | 3 |
| 10 | Fabrication of PTFE/Nomex fabric/phenolic composites using a layer-by-layer self-assembly method for tribology field application显示文摘Fabric composites are widely applied as self-lubricating liner for radial spherical plain bearings owing to their excellent mechanical and tribological properties.Nevertheless,the poor interfacial strength between fibers and the resin matrix limits the performance of composites utilized as tribomaterials.To overcome this drawback,a mild layer-by-layer(LbL)self-assembly method was successfully used to construct hybrid fabric composites in the present work.In addition,this investigation addressed the effect of self-assembly cycles on the friction and wear behaviors of hybrid fabric composites under dry sliding condition.The results demonstrate that fabric composites with three or more self-assembly cycles have significantly enhanced surface activities and anti-wear performances.The results obtained in this work can provide guidance in the preparation of self-lubricating liner composites and highlight how the LbL self-assembly techniques could influence the properties of hybrid fabric composites. | Mingming YANG Zhaozhu ZHANG Junya YUAN Liangfei WU Xin ZHAO Fang GUO Xuehu MEN Weimin LIU | 2020 | Friction2020，8，2： | 3 |
| 11 | Relationships of surface oxygen vacancies with photoluminescence and photocatalytic performance of ZnO nanoparticles显示文摘The ZnO nanoparticles are prepared by a precipitation process, and also are char- acterized by means of the modern testing techniques such as XPS, ESR, SPS and PL. The ac- tivity of the as-prepared ZnO is evaluated in the photocatalytic oxidation of gas phase n-C7H16. The relationships of surface oxygen vacancies (SOV) with photoluminescence (PL) and photo- catalytic performance are discussed in details. The results show that the smaller the particle size, the larger the SOV content, the stronger the PL signal, the higher the photocatalytic activity, in- dicating that the SOV, PL and photocatalytic activity have inherent relationships. This was be- cause of the reasons that the PL signal is attributed to the free and binding excitons resulting from the SOV, while the SOV is favorable for a photocatalytic oxidation reaction since the SOV can easily capture the photoinduced electrons, and the captured electrons had strong interac- tions with the adsorbed oxygen. In addition, the surface states of ZnO nanoparticles, arising from the SOV and oxygen species, are very abundant. | JING Liqiang YUAN Fulong HOU Haige XIN Baifu CAI Weimin FU Honggang | 2005 | Science China Chemistry2005，48，1： | 3 |
| 12 | A novel Cu-doped high entropy alloy with excellent comprehensive performances for marine application显示文摘High entropy alloy(HEA)has attracted great interests as one of the promising multifunctional materials in marine applications.However,Cu as an effective biocide tends to form segregation in HEA,which could deteriorate corrosion and induce brittle fracture.Herein,we report a strategy to tailor the existing form of Cu in HEA from undesired large-scale segregation to uniform distribution with dispersed nanoscale precipitation,while retaining the unique structure characteristics of HEA.Eliminating Cu segregation improves toughness and avoids serious corrosion in the grain boundary.Uniform distribution with dispersed nanoscale precipitation of Cu further enhances the antifouling and lubricating abilities of Cu-doped HEA.Tailored AlCoCrFeNiCu_(0.5)HEA in this work has excellent comprehensive properties combining good mechanical properties,outstanding antifouling abilities,superior resistance to corrosion and wear.Furthermore,the corresponded mechanisms are discussed in terms of Cu-segregation-eliminated,nanoscale-Cu-precipitate-forming and comprehensive properties. | Yuan Yu Nannan Xu Shengyu Zhu Zhuhui Qjao Jianbin Zhang Jun Yang Weimin Liu | 2021 | Journal of Materials Science & Technology2021，，10： | 3 |
| 13 | Exploring the Dynamic X-ray Universe:Scientific Opportunities for the Einstein Probe Mission显示文摘Time-domain astrophysics will enter a golden era towards the end of this decade with the advent of major facilities across the electromagnetic spectrum and in the multi-messenger realms of gravitational wave and neutrino.In the soft X-ray regime,the novel micro-pore lobster-eye optics provides a promising technology to realise,for the first time,focusing X-ray optics for wide-angle monitors to achieve a good combination of sensitivity and wide field of view.In this context Einstein Probe,a soft X-ray all-sky monitor mission,was proposed and selected as a candidate mission of priority in the space science programme of the Chinese Academy of Sciences.This paper reviews the most important science developments and key questions in this field towards 2020 and beyond,and how to achieve them technologically.It also introduces the Einstein Probe mission,including its key science goals and mission definition,as well as some of the key technological issues. | YUAN Weimin OSBORNE Julian P ZHANG Chen WILLINGALE Richard | 2016 | 空间科学学报2016，36，2： | 3 |
| 14 | Application of piezoelectric fiber composite actuator to aircraft wing for aerodynamic performance improvement显示文摘The application of actuator made of piezoelectric material,particularly the advanced piezoelectric fiber composite due to the rapid development of smart materials and structures and active control technology in aviation and aerospace industry,to aircraft for performance enhancements such as flight control,aerodynamic force optimization,structure weight reduction,and overall aircraft design represents a new challenge to researches.It is considered as one of the key technologies for developing future flight vehicle.An approach with virtual control surface instead of conventional control surface to control aerodynamic force distribution and flight performance by use of piezoelectric fiber composite actuators distributed on wing surface is presented here.Particularly,the design and implementation of increasing lift force,providing roll maneuver,decreasing induced drag and wing root moment in different flight environments by the same structure control platform are studied.The control effect and sensitivity are examined quantitatively.Generally speaking,better control effect can be obtained by making better use of aeroelastic character to enlarge the actuation strain produced by piezoelectric material. | LI Min YUAN JunXian GUAN De CHEN WeiMin | 2011 | Science China(Technological Sciences)2011，54，2： | 2 |
| 15 | Integrated single-cell RNA sequencing analysis reveals distinct cellular and transcriptional modules associated with survival in lung cancer显示文摘Lung adenocarcinoma(LUAD)and squamous carcinoma(LUSC)are two major subtypes of non-small cell lung cancer with distinct pathologic features and treatment paradigms.The heterogeneity can be attributed to genetic,transcriptional,and epigenetic parameters.Here,we established a multi-omics atlas,integrating 52 single-cell RNA sequencing and 2342 public bulk RNA sequencing.We investigated their differences in genetic amplification,cellular compositions,and expression modules.We revealed that LUAD and LUSC contained amplifications occurring selectively in subclusters of AT2 and basal cells,and had distinct cellular composition modules associated with poor survival of lung cancer.Malignant and stage-specific gene analyses further uncovered critical transcription factors and genes in tumor progression.Moreover,we identified subclusters with proliferating and differentiating properties in AT2 and basal cells.Overexpression assays of ten genes,including sub-cluster markers AQP5 and KPNA2,further indicated their functional roles,providing potential targets for early diagnosis and treatment in lung cancer. | Li Zhang Yiming Zhang Chengdi Wang Ying Yang Yinyun Ni Zhoufeng Wang Tingting Song Menglin Yao Zhiqiang Liu Ningning Chao Yongfeng Yang Jun Shao Zhidan Li Ran Zhou Li Chen Dan Zhang Yuancun Zhao Wei Liu Yupeng Li Ping He Jing-wen Lin Yuan Wang Kang Zhang Lu Chen Weimin Li | 2022 | Signal Transduction and Targeted Therapy2022，7，2： | 2 |
| 16 | METTL3-mediated m^(6)A RNA methylation regulates dorsal lingual epithelium homeostasis显示文摘The dorsal lingual epithelium,which is composed of taste buds and keratinocytes differentiated from K14^(+)basal cells,discriminates taste compounds and maintains the epithelial barrier.N6-methyladenosine(m^(6)A)is the most abundant mRNA modification in eukaryotic cells.How METTL3-mediated m^(6)A modification regulates K14^(+)basal cell fate during dorsal lingual epithelium formation and regeneration remains unclear.Here we show knockout of Mettl3 in K14^(+)cells reduced the taste buds and enhanced keratinocytes.Deletion of Mettl3 led to increased basal cell proliferation and decreased cell division in taste buds.Conditional Mettl3 knock-in mice showed little impact on taste buds or keratinization,but displayed increased proliferation of cells around taste buds in a protective manner during post-irradiation recovery.Mechanically,we revealed that the most frequent m^(6)A modifications were enriched in Hippo and Wnt signaling,and specific peaks were observed near the stop codons of Lats1 and FZD7.Our study elucidates that METTL3 is essential for taste bud formation and could promote the quantity recovery of taste bud after radiation. | Qiuchan Xiong Caojie Liu Xin Zheng Xinyi Zhou Kexin Lei Xiaohan Zhang Qian Wang Weimin Lin Ruizhan Tong Ruoshi Xu Quan Yuan | 2022 | International Journal of Oral Science2022，14，3： | 2 |
| 17 | Monitoring the charge bunch-by-bunch for the SSRF storage ring:Development and application显示文摘Bunch charge uniformity controlling is very important for top-up operation of the storage ring.In order to monitor filling pattern and measure the bunch charge precisely,a PXI waveform digitizer-based data acquisition system has been developed to retrieve bunch charge information from BPM pickup signals.An effective sampling rate is extended to 400 GHz by waveform rebuilding technology,which overlays multi-turn data into single turn with real time sampling rate of 8 GHz.An on-line evaluation indicates that resolution and linearity of the charge measurement are better than 0.5% at input range of 0.5-12nC. | LENG Yongbin YAN Yingbin YU Luyang YUAN Renxian CHEN Zhichu ZHOU Weimin | 2010 | Nuclear Science and Techniques2010，21，4： | 2 |
| 18 | Effects of Ti and Cu on the Microstructure Evolution of AlCoCrFeNi High-Entropy Alloy During Heat Treatment显示文摘The microstructure evolution of AlCoCrFeNiTi0.5 alloy and AlCoCrFeNiCu alloy during heat treatment was systematically studied,to reveal the influence rules of chemical activity of adding element on the microstructure evolution of AlCoCrFeNi system.Owing to the negative mixing enthalpy with the constituent elements,Ti element was mainly dissolved in the Al-Nirich phases,and aggravated the lattice distortion of B2 phase.The structure variation of BCC phase by adding Ti inhibited the formation of FCC phase and enhanced the precipitation ofσphase during heat treatment.Owing to the positive mixing enthalpy with constituent elements,Cu element tended to be repelled to the ID region and formed metastable Cu-rich FCC1 phase which would transform into Cu-Al-Ni-rich FCC2 phase with increasing temperature.The addition of Cu inhibited the precipitation ofσphase during heat treatment.Adding Ti maintained the stable dendritic morphology,while adding Cu reduced the thermal stability of microstructure.Two dramatic morphology changes occurred at 1000℃and 1100℃in the AlCoCrFeNiCu alloy.The lattice distortion of phase in AlCoCrFeNiTi0.5 alloy was aggravated with increasing temperature up to 800℃,then relaxed together with the dissolution ofσphase when temperature was above 900℃.The variation in lattice distortion dominated the hardness of AlCoCrFeNiTi0.5 alloy.With increasing heating temperature,the increasing volume fraction of region with FCC structure due to the transformation between FCC phases,and the pronounced coarsening in microstructure due to the reduced thermal stability,resulted in the mainly decreasing trend in the hardness of AlCoCrFeNiCu alloy. | Yuan Yu Peiying Shi Kai Feng Jiongjie Liu Jun Cheng Zhuhui Qiao Jun Yang Jinshan Li Weimin Liu | 2020 | Acta Metallurgica Sinica(English Letters)2020，33，8： | 2 |
| 19 | Novel completed biodegradable polymer sirolimus-eluting stent versus durable polymer sirolimus-eluting stent in de novo lesions: nine-month angiographic and three-year clinical outcomes of HOPE trial显示文摘 | Yuan Fei Chen Xin Song Xiantao Wang Dongqi Zhang Zheng Li Weimin Li Zhanquan Li Hui Chen Xinyi Huo Yong Wang Lefeng Lu Caiyi Lu Qinghua Xu Bo Li Wei Lyu Shuzheng | 2014 | Chinese Medical Journal2014，，14： | 2 |
| 20 | Novel physical probe configurations in a multi-probe based 3D MIMO OTA setup显示文摘In this paper, channel spatial characteristics which mainly depend on the spatial correlation are selected as the significant factors in over-the-air(OTA) testing for multiple input multiple output(MIMO) devices. The multi-probe anechoic chamber method, a promising candidate of the MIMO OTA testing methods, can reproduce the multipath environments in a controllable manner. A novel physical configuration based on the variation of relative positions of probes in a MIMO OTA setup is put forward to obtain better spatial characteristics. Two physical configurations are presented to make a comparison with the typical configuration in this paper. The simulation results show that by making a proper probe configuration, good channel simulation accuracy can be achieved. Meanwhile, in order to get better performance of emulating channel spatial characteristics, probes in the first and the last probe rings should be placed symmetrically in three dimensional(3D) physical probe configuration. | Wang Weimin Li Muyuan Liu Yuan'an Wu Yongle Li Shulan | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，1： | 1 |
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