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| 1 | Cold-chain transportation in the frozen food industry may have caused a recurrence of COVID-19 cases in destination:Successful isolation of SARS-CoV-2 virus from the imported frozen cod package surface显示文摘Coronavirus disease 2019(COVID-19)pandemic has spread in 220 countries/regions towreak havoc to human beings around theworld.At present,the second wave of COVID-19 has begun in many European countries.The complete control of COVID-19 is very urgent.Although China quickly brought the virus under control,there have been eight sporadic outbreaks in China since then.Both in Xinfadi of Beijing and Dalian outbreak of COVID-19,environmental swab samples related to imported cold chain food were tested nucleic acid positive for SARS-CoV-2.In this outbreak in Qingdao,we directly isolated SARS-CoV-2 from the cod outer package's surface swab samples.This is the first time worldwide,SARS-CoV-2 were isolated from the imported frozen cod outer package's surface,which showed that imported frozen food industry could import SARS-CoV-2 virus. | Peipei Liu Mengjie Yang Xiang Zhao Yuanyuan Guo Liang Wang Jing Zhang Wenwen Lei Weifang Han Fachun Jiang William J.Liu George F.Gao Guizhen Wu | 2020 | Biosafety and Health2020，2，4： | 41 |
| 2 | Failure Analysis of Aviation Torsional Springs显示文摘裂缝和破裂发生在汇编进程期间到在航空机制使用的扭力的弹簧的一种类型。除视觉检查以外,另外的试验性的技术使用了因为调查:1 ) 由扫描电子显微镜学(SEM ) 的破裂特征,损坏形态学和金属断面的显微镜观察, 2 ) 盖住的光谱分析, 3 ) 裂缝的 metallographic 观察并且 4 ) 氢内容测试。结果通过制造过程和试验性的数据的分析被获得。因为微观结构的变化都没被发现,失败与材料无关。裂缝和破裂在内部表面上开始,裂缝在镉 plating 前并且在弯屈以后开始。没有明显的压力腐蚀裂缝在裂缝来源区域附近被发现。裂缝的开的方向与剩余一致春天的张力的应力内部表面,和弹簧是容易的联系在弯屈的春天和镉 plating 之间的氢媒介。裂缝被引起由导致氢在剩余的行动下面裂开推迟张力的应力和氢。 | HOU Weiguo ZHANG Weifang LIU Xiao WANG Zongren DING Meili | 2011 | Chinese Journal of Aeronautics2011，24，4： | 7 |
| 3 | Triglycerides and ratio of triglycerides to high-density lipoprotein cholesterol are better than liver enzymes to identify insulin resistance in urban middle-aged and older non-obese Chinese without diabetes显示文摘 | Sun Yu Li Wenjuan Hou Xinguo Wang Chuan Li Chengqiao Zhang Xiuping Yang Weifang Ma Zeqiang Wang Weiqing Ning Guang Zheng Huizhen Ma Aixia Song Jun Lin Peng Liang Kai Liu Fuqiang Gong Lei Wang Meijian Xiao Juan Yan Fei Yang Junpeng Wang Lingshu Tian Meng Liu Jidong Zhao Ruxing Zhu Ping Chen Li | 2014 | Chinese Medical Journal2014，，10： | 7 |
| 4 | Incorporating the magnetic alignment of GO composites into Pebax matrix for gas separation显示文摘The mixed matrix membranes(MMMs) were developed by incorporating graphite oxide(GO) flakes functionalized with iron oxide(Fe_3O_4) into Pebax matrix. The Pebax/Fe_3O_4–GO MMMs were used to separate CO_2/CH_4 and CO_2/N_2 gas mixture. The results showed that the MMMs with magnetic alignment presented the better gas separation performance than that of random arrangement of Pebax/Fe_3O_4–GO mixed matrix membranes. The reason was that the Fe_3O_4–GO flakes arranged magnetically in the membrane played a multiple role in improving the performance of MMMs. Firstly, under the action of the magnetic field,the magnetic alignment of Fe_3O_4–GO flakes in Pebax matrix constructed the shorter transfer path for gas molecule, increasing the CO_2 permeability. Secondly, the hydroxyl groups in GO flakes and the presence of Fe_3O_4 have stronger binding force for water, improving the CO_2 solubility selectivity. Thirdly, the better interaction between the magnetic alignment of GO composites and polymer matrix, reduced the interface defects. Especially, the optimum gas separation performance was obtained at the Fe_3O_4–GO flakes content of 3 wt% in Pebax matrix at vertical arrangement with selectivity of 47 and 75 for CO_2/CH_4 and CO_2/N_2, respectively, and CO_2 permeability of 538 Barrer at 0.2 MPa and room temperature. | Weifang Zhu Yun Qin Zhongming Wang Jianshu Zhang Ruili Guo Xueqin Li | 2019 | Journal of Energy Chemistry2019，28，4： | 5 |
| 5 | Optimal Design and Force Control of a Nine-Cable-Driven Parallel Mechanism for Lunar Takeoff Simulation显示文摘Traditional simulation methods are unable to meet the requirements of lunar takeo simulations, such as high force output precision, low cost, and repeated use. Considering that cable-driven parallel mechanisms have the advantages of high payload to weight ratio, potentially large workspace, and high-speed motion, these mechanisms have the potential to be used for lunar takeo simulations. Thus, this paper presents a parallel mechanism driven by nine cables. The purpose of this study is to optimize the dimensions of the cable-driven parallel mechanism to meet dynamic workspace requirements under cable tension constraints. The dynamic workspace requirements are derived from the kinematical function requests of the lunar takeo simulation equipment. Experimental design and response surface methods are adopted for building the surrogate mathematical model linking the optimal variables and the optimization indices. A set of dimensional parameters are determined by analyzing the surrogate mathematical model. The volume of the dynamic workspace increased by 46% after optimization. Besides, a force control method is proposed for calculating output vector and sinusoidal forces. A force control loop is introduced into the traditional position control loop to adjust the cable force precisely, while controlling the cable length. The e ectiveness of the proposed control method is verified through experiments. A 5% vector output accuracy and 12 Hz undulation force output can be realized. This paper proposes a cable-driven parallel mechanism which can be used for lunar takeo simulation. | Wangmin Yi Yu Zheng Weifang Wang XiaoqiangTang Xinjun Liu Fanwei Meng | 2019 | Chinese Journal of Mechanical Engineering2019，32，4： | 5 |
| 6 | Arsenic(V)removal from groundwater by GE-HL nanofiltration membrane:effects of arsenic concentration,pH,and co-existing ions显示文摘A laboratory-scale investigation was performed to study arsenic(As(V))removal by negatively charged GE-HL nanofiltration(NF)membrane in simulated drinking water.Effects of As(V)concentration(0–200μg·L–1),pH,and co-ions and counter-ions were investigated.The NF membrane presented good stability,and the rejection rates exceeded 90%.The rejection rates of As(V)decreased with the increase of As(V)concentration,while it increased with the increase of pH(reached 96%at pH 6.75).Moreover,a negative relationship was observed between the co-existing ions of Cl^(–),Na^(+),SO_(4)^(2–),and Ca^(2+)and the removal of As(V),in which bivalent ions presented more significant effects than monovalent ions. | Xiaowei WANG Wenjun LIU Desheng LI Weifang MA | 2009 | Frontiers of Environmental Science & Engineering2009，3，4： | 5 |
| 7 | Identification of Overlapping Protein Complexes Using Structural and Functional Information of PPI Network显示文摘An identification algorithm of overlapping protein complexes is put forward by simultaneously considering the topological structural and biological functional information of Protein-protein interaction(PPI) network.Main works include: constructing the edge weight of weighted PPI network on the basis of structural and functional information of PPI network to more accurately describe the correlation between protein vertices; improving the Newman algorithm to make it applicable to weighted PPI network and thus to identify overlapping protein complexes; and providing the denoising criteria based on the structural and function information of PPI network: connections which have no contribution to the high aggregation of PPI network or which are among proteins of independent functions are judged to be false positive connections. The experimental results on the dataset of saccharomyces cerevisiae PPI network show that the proposed algorithm has higher identification accuracy and matching rate when compared with the current representative identification algorithms of protein complexes. | WANG Xuesong CHENG Yuhu SUN Weifang | 2015 | Chinese Journal of Electronics2015，24，3： | 4 |
| 8 | A CCAAT-binding factor,SlNFYA10,negatively regulates ascorbate accumulation by modulating the D-mannose/L-galactose pathway in tomato显示文摘Ascorbic acid(AsA),an important antioxidant and growth regulator,and it is essential for plant development and human health.Specifically,humans have to acquire AsA from dietary sources due to their inability to synthesize it.The AsA biosynthesis pathway in plants has been elucidated,but its regulatory mechanism remains largely unknown.In this report,we biochemically identified a CCAAT-box transcription factor(SlNFYA10)that can bind to the promoter of SlGME1,which encodes GDP-Man-3’,5’-epimerase,a pivotal enzyme in the D-mannose/L-galactose pathway.Importantly,SlNFYA10 simultaneously binds to the promoter of SlGGP1,a downstream gene of SlGME1 in the Dmannose/L-galactose pathway.Binding assays in yeast and functional analyses in plants have confirmed that SlNFYA10 exerts a negative effect on the expression of both SlGME1 and SlGGP1.Transgenic tomato lines overexpressing SlNFYA10 show decreased levels of SlGME1 and SlGGP1 abundance and AsA concentration in their leaves and fruits,accompanied by enhanced sensitivity to oxidative stress.Overall,SlNFYA10 is the first CCAAT-binding factor identified to date to negatively regulate the AsA biosynthetic pathway at multiple sites and modulate plant responses to oxidative stress. | Weifang Chen Tixu Hu Jie Ye Bing Wang Genzhong Liu Ying Wang Lei Yuan Jiaming Li Fangman Li Zhibiao Ye Yuyang Zhang | 2020 | Horticulture Research2020，7，1： | 3 |
| 9 | Effect of Dietary Olaquindox on the Growth of Large Yellow Croaker(Pseudosciaena crocea R.) and the Distribution of Its Residues in Fish Tissues显示文摘Olaquindox(OLA), one of quinoxaline-N, N-dioxides, has been put under ban. However it was used as a medicinal feed additive early; it promotes the growth of livestock and prevents them from dysentery and bacterial enteritis. In this study, we evaluated the effect of dietary OLA on the growth of large yellow croaker(Pseudosciaena crocea R.) and the histological distribution of OLA and its metabolite 3-methyl-quinoxaline-2-carboxylic acid(MQCA) in fish tissues. Four diets containing 0(control), 42.5, 89.5 and 277.2 mg kg-1 OLA, respectively, were formulated and tested, 3 cages(1.0 m × 1.0 m × 1.5 m) each diet and 100 juveniles(9.75 ± 0.35 g) each cage. The fish were fed to satiation twice a day at 05:00 am and 17:00 pm for 8 weeks. The survival rate of fish fed the diet containing 42.5 and 89.5 mg kg-1 OLA was significantly higher than that of fish fed the diet containing 0 and 277.2 mg kg-1 OLA(P < 0.05), while the weight gain rate of fish fed the diet containing 42.5 and 89.5 mg kg-1 OLA was significantly higher than that of fish fed the diet without OLA(control)(P<0.05), but similar to that of fish fed the diet with 277.2 mg kg-1 OLA. Fish fed the diet with 277.2 mg kg-1 OLA had the highest content of OLA and MQCA in liver(3.44 and 0.39 mg kg-1, respectively), skin(0.46 and 0.09 mg kg-1, respectively) and muscle(0.24 and 0.06 mg kg-1, respectively). In average, fish fed the diet containing OLA had the highest content of OLA and MQCA in liver which was followed by skin and muscle(P < 0.05), whereas OLA and MQCA were not detectable in control. Our findings demonstrated that OLA and MQCA accumulated in large yellow croaker when it was fed with the diet containing OLA, thus imposing a potential safety risk to human health. | LI Huitao WANG Weifang MAI Kangsen AI Qinghui ZHANG Chunxiao ZHANG Lu | 2014 | Journal of Ocean University of China2014，13，5： | 3 |
| 10 | Characterization and Proteomic Analysis of Novel Rice Lesion Mimic Mutant with Enhanced Disease Resistance显示文摘Lesion mmic mutants(LMMs)are plants that spontaneously form lesions without pathogeninfection or external stimulus and exhibit resistance to pathogens.Here,a rice LMM was created by ethylmethane sulfonate mutagenesis,named as hpil(hydrogen peroxide induced lesion).Diaminobenzidineand trypan blue staining showed that large amounts of H_(2)O_(2) were produced and cell death was occurredat and around the parts of lesion mimic in the rice leaves.The phenotype of hpil is controlled by a singlerecessive gene,localized at a 2 Mb interval on chromosome 2.The data suggested that hpil is a novelLMM with enhanced bacterial and fungal disease resistance,and multiple pathogenesis-related proteins(PRs)were up-regulated.The proteomes of leaves at three positions(different degrees of lesion mimicseverity)were characterized in hpil compared with its wild type plant.Differentially expressed proteinswere detected by two dimensional difference gel electrophoresis and 274 proteins were identified byMALDITOF/TOFTM.These proteins were related to metabolic process,cellular process and response tostimulus,with mostly down-regulated in hpil leaves.Many of these proteins were related to the Calvincycle,photosynthetic electron transport chain,glycolysis/gluconeogenesis and phosphonates pathways.Some resistance-related proteins including 14-3-3 proteins,OsPR10 and antioxidases such asperoxidase,superoxide dismutase and ascorbate peroxidase were up-regulated in leaves with lesionmimic.These results provide the foundation for cloning of the target gene and shed light on themechanism involved in autaimmunity of rice. | Yang Yong Lin Qiujun Chen Xinyu Liang Weifang Fu Yuwen Xu Zhengjin Wu Yuanhua Wang Xuming Zhou Jie Yu Chulang Yan Chengqi Mei Qiong Chen Jianping | 2021 | Rice science2021，28，5： | 2 |
| 11 | Effects of psycho-scene-drama on empathic ability of patients with chronic schizophrenia显示文摘Objective:The purpose of the current study was to determine the effects of psycho-scene drama on the empathic ability of patients with chronic schizophrenia.Methods:One hundred sixteen in-patients with chronic schizophrenia were randomly di-vided into study and control groups(n=58 cases each).The original anti-psychotic drugs were not changed in either group.In the study group,the therapy was combined with psychological scene drama with a treatment course of 3 months.Before and after treatment,the interpersonal reaction index scale(Chinese version[IRI-C]),negative syndrome scale(SANS),social function assessment scale for patients with mental diseases(SSPI),Rosenberg self-esteem scale(SES),the emotional-social loneliness inventory(ESLI),and the Texas social behavior inventory(TSBI)were utilized for measurements.Results:A comparison of the IRI-C total,PT,FS,and EC factor scores before and after treatment in the study group was significantly different(P<0.01);the PD factor score before and after treatment was not statistically significant(P>0.05).A comparison of the IRI-C total score and each factor score before and after treatment in the control group was not significantly different(P>0.05).A comparison of the IRI-C total,PT,and EC factor scores between the study and control groups after treatment was significantly different(P<0.05).A comparison of the FS factor score between the study and control groups before and after treatment was significantly different(P<0.01);the PD factor score was not significantly different(P>0.05).A comparison of the SANS total,SSPI total,SES total,and ESLI total scores between the two groups after treatment was significantly different(P<0.05).Conclusion:The psycho-scene drama can improve the empathic ability of patients with chronic schizophrenia,improve the negative symptoms and social function,increase the self-esteem and self-confidence,and reduce the loneliness in social interactions. | Hongmei Tian Weifang Niu Ping Liu Na Wang Huijing Yu Zhanhong Zhao | 2014 | Family Medicine and Community Health2014，2，4： | 2 |
| 12 | Novel optical properties and induced magnetic moments in Ru-doped hybrid improper ferroelectric Ca3Ti2O7显示文摘Hybrid improper ferroelectric Ca3Ti2O7 and Ca3Tii 9RuO.iO7 ceramics were successfully synthesized by conventional solid-state reaction method.Two strongest diffraction peaks located around 2θ=33°shifted towards the lower angle region with Ru substitution,reflecting structure variation.Grain growth and higher oxygen vacancy concentration after doping resulted in a reduction in the coercive field about 20 kV/cm.Optical bandgap estimated by UV-vis diffuse reflectance(DR)spectrum and X-ray photoelectron spectroscopy(XPS)valence band spectra showed a decreasing trend due to the existence of impurity energy level upon Ru doping,which was consistent with the results of first-principles calculations.The origin of the unexpected induced magnetic moments in Ru-dope Ca3Ti2O7 is also discussed. | Xingxing WU Shouyu WANG Winnie WONG-NG Qiang GU Yao JIANG Chao WANG Shuang MA Weifang LIU | 2021 | Journal of Advanced Ceramics2021，10，1： | 2 |
| 13 | A novel synthetic small molecule YF-452 inhibits tumor growth through antiangiogenesis by suppressing VEGF receptor 2 signaling显示文摘Tumor angiogenesis is characterized by abnormal vessel morphology, endowing tumor with highly hypoxia and unresponsive toward treatment. To date, mounting angiogenic factors have been discovered as therapeutic targets in antiangiogenic drug development. Among them, vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors exerts potent antiangiogenic activity in tumor therapy. Therefore, it may provide a valid strategy for cancer treatment through targeting the tumor angiogenesis via VEGFR2 pathway. In this study, we established a high-profile compounds library and certificated a novel compound named N-(N-pyrrolidylacetyl)-9-(4-bromobenzyl)-1,3,4,9-tetrahydro-β-carboline (YF-452), which remarkably inhibited the migration, invasion and tube-like structure formation of human umbilical vein endothelial cells (HUVECs) with little toxicity invitro. Rat thoracic aorta ring assay indicated that YF-452 significantly blocked the formation of microvascular exvivo. In addition, YF-452 inhibited angiogenesis in chick chorioallantoic membrane (CAM) and mouse corneal micropocket assays. Moreover, YF-452 remarkably suppressed tumor growth in xenografts mice model. Furthermore, investigation of molecular mechanism revealed that YF-452 inhibited VEGF-induced phosphorylation of VEGFR2 kinase and the downstream protein kinases including extracellular signal regulated kinase (ERK), focal adhesion kinase (FAK) and Src. These results indicate that YF-452 inhibits angiogenesis and may be a potential antiangiogenic drug candidate for cancer therapy. | Yongrui Liu Yuan He Feifei Yang Xiaonan Cong Jinhua Wang Shihong Peng Dan Gao Weifang Wang Liping Lan Xuexiang Ying Mingyao Liu Yihua Chen Zhengfang Yi | 2017 | Science China(Life Sciences)2017，60，2： | 2 |
| 14 | STUDY ON THE RESPONSE TO LOW-VELOCITY IMPACT OF A COMPOSITE PLATE IMPROVED BY SHAPE MEMORY ALLOY显示文摘Improvement from the pseudo-elastic effect of shape memory alloy (SMA) on the low-velocity impact (LVI) resistance of a composite plate is investigated by the finite element method (FEM).The stiffness matrix of the dynamic finite element equation is established step by step and the martensite fraction is obtained at each time step.The direct Newmark integration method is employed in solving the dynamic finite element equation,while the impact contact force is determined using the modified Hertz's law.It is found that SMA can effectively improve the performance of a composite structure subjected to low-velocity impact.Numerical results show that the deflection of a SMA-hybrid composite plate has been reduced approximately by thirty percent when the volume fraction of the embedded SMA reaches 0.3. | Ying Wu YongdongWu Yuanxun Wang Weifang Zhong | 2007 | Acta Mechanica Solida Sinica2007，20，4： | 2 |
| 15 | Electricity generation from wastewater using an anaerobic fluidized bed microbial fuel cell显示文摘 | Kong Weifang Guo Qingjie Wang Xuyun Yue Xuehai | | 0，，21： | 1 |
| 16 | Effect of Fe on the phase and microstrncture of TiC-Fe cermets by combustion synthesis/quasi-isostatic pressing显示文摘 | ZHANG Weifang ZHANG Xinghong WANG Jianli | 2004 | Materials Science and Engineering A2004，381，1： | 1 |
| 17 | Purification and structural characterization of Chinese yam polysaccharide and its activities显示文摘 | YANG Weifang WANG Ying LI Wueping | 2015 | Carbohydrate Polymers2015，117，： | 1 |
| 18 | 显示文摘 | Zhang Weifang Zhang Xinghong Wang Jianli | 2004 | Materials Science and Engineering A2004，381，： | 1 |
| 19 | AN EFFICIENT GENETIC ALGORITHM FOR LARGE SCALE BUILT-UP STRUCTURAL OPTIMIZATION显示文摘In this paper,a new zigzag method for plate structures and a geneticalgorithm (GA) of dynamic source seed spaces are developed and a combination ofthem is used to deal with large scale built-up structural optimization.The new GAcombined with the zigzag method can work efficiently when coping with large scalestructural optimization included displacement and stress constraints.Examples showthat this GA is robust and can be used for many complex structural optimizationproblems. | Wang Shigang Yao Jianchu Huang Yuying Zhong Weifang Lin Jinming(Huazhong University of Science and Technology Wuhan,Hubei,430074 P.R.China) | 1994 | Acta Mechanica Solida Sinica1994，7，1： | 1 |
| 20 | Interleukin-8-251A/T polymorphism and Helicobacter pylori infection influence risk for the development of gastric cardiac adenocarcinoma in a high-incidence area of China显示文摘 | Liwei Zhang Chaoqun Du Xiaoqing Guo Li Yuan Weiwei Niu Weifang Yu Limian Er Shijie Wang | 2010 | Molecular Biology Reports2010，，8： | 1 |
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