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| 1 | Porosity and permeability evolution and evaluation in anisotropic porosity multiscale-multiphase-multicomponent structure显示文摘Based on the hybrid hypersingular integral equation-lattice Boltzmann methods (HHIE-LBM), the porosity and permeability evolution and evaluation process in anisotropic saturated porosity multiscale-multiphase-multicomponent (ASP-MS-MP-MC) structures under ultra high temperature and pressure conditions was analyzed on parallel CPU and GPU platforms. First, virtual physical models at multi-spatial scales (2 μm, 5 μm and 10 μm) were restructured by computerized microtomography technology and data. Second, using HHIE-LBM methods, the anisotropic porosity and permeability tensor at core level and pore level under ultra high temperature and pressure conditions were calculated. Third, the evolution and evaluation process of the porosity and permeability as a function of multi temporal spatial scales was investigated. Finally, the relationship between porosity and permeability and ASP-MS-MP-MC structures (micro-meso-macro-scale) was explored. | ZHU BoJing CHENG HuiHong QIAO YanChao LIU Chang SHI YaoLin ZHANG Kai SUN DongSheng LIN WeiRen | 2012 | Chinese Science Bulletin2012，57，4： | 11 |
| 2 | Cylindrical vector beam-excited frequency-tunable second harmonic generation in a plasmonic octamer显示文摘We report a method to tune the second harmonic generation(SHG) frequency of a metallic octamer by employing cylindrical vector beams as the excitation. Our method exploits the ability to spatially match the polarization state of excitations with the fundamental target plasmonic modes, enabling flexible control of the SHG resonant frequency.It is found that SHG of the octamer is enhanced over a broad band(400 nm) by changing the excitation from the linearly polarized Gaussian beam to radially and azimuthally polarized beams. More strikingly, when subjected to an azimuthally polarized beam, the SHG intensity of the octamer becomes 30 times stronger than that for the linearly polarized beam even in the presence of Fano resonance. | FAJUN XIAO WUYUN SHANG WEIREN ZHU LEI HAN MALIN PREMARATNE TING MEI JIANLIN ZHAO | 2018 | Photonics Research2018，6，3： | 6 |
| 3 | Experimental demonstration of an electrically tunable broadband coherent perfect absorber based on a graphene–electrolyte–graphene sandwich structure显示文摘We propose and experimentally demonstrate the operation of an electrically tunable, broadband coherent perfect absorption(CPA) at microwave frequencies by harnessing the CPA features of a graphene–electrolyte–graphene sandwich structure(GSS). Using both a simplified lumped circuit model and full-wave numerical simulation, it is found that the microwave coherent absorptivity of the GSS can be tuned dynamically from nearly 50% to 100% by changing the Fermi level of the graphene. Strikingly, our simplified lumped circuit model agrees very well with the full-wave numerical model, offering valuable insight into the CPA operation of the device. The angle dependency of coherent absorption in the GSS is further investigated, making suggestions for achieving CPA at wide angles up to 80°. To show the validity and accuracy of our theory and numerical simulations, a GSS prototype is fabricated and measured in a C-band waveguide system. The reasonably good agreement between the experimental and the simulated results confirms that the tunable coherent absorption in GSS can be electrically controlled by changing the Fermi level of the graphene. | JIN ZHANG XINGZHAN WEI MALIN PREMARATNE WEIREN ZHU | 2019 | Photonics Research2019，7，8： | 4 |
| 4 | Selective excitation of a three-dimensionally oriented single plasmonic dipole显示文摘We experimentally demonstrate a scheme to deterministically excite a three-dimensionally oriented electric dipole in a single Au nanosphere by using a tightly focused radially polarized beam whose focal field possesses polarization states along three-dimensional(3D) orientations owing to the spatial overlap between longitudinal and radial electric field components. Experiment observations indicate that the orientation of an excited dipole moment gradually changes from out-of-plane to in-plane when the nanosphere is moved away from the beam center, which is reconfirmed by full-wave simulations. Moreover, rigorous calculation based on Mie theory reveals that a reduced effective ambient permittivity accompanies the rotation of the dipole moment, leading to a blue-shifted and narrowed resonance peak. We envision that our results could find applications in detecting the 3D orientation of isolated molecules and benefit the fine manipulation of light–matter interactions at the single-molecule level. | FAJUN XIAO GUANGLIN WANG XUETAO GAN WUYUN SHANG SHIYIN CAO WEIREN ZHU TING MEI MALIN PREMARATNE JIANLIN ZHAO | 2019 | Photonics Research2019，7，6： | 3 |
| 5 | Hybrid membrane computing and pigeon-inspired optimization algorithm for brushless direct current motor parameter design显示文摘In this paper, a novel approach is proposed for solving the parameter design problem of brushless direct current(BLDC) motor, which is based on the membrane computing(MC) and pigeon-inspired optimization(PIO) algorithm. The motor parameter design problem is converted to an optimization problem with five design parameters and six constraints. The PIO algorithm is introduced into the framework of MC for improving the global convergence performance. The hybrid algorithm can improve the population diversity with better searching efficiency. Comparative simulations are conducted, and comparative results are given to show the feasibility and effectiveness of our proposed hybrid algorithm for high nonlinear optimization problems. | DENG YiMin ZHU WeiRen DUAN HaiBin | 2016 | Science China(Technological Sciences)2016，59，9： | 3 |
| 6 | Will the Historic Southeasterly Wind over the Equatorial Pacific in March 2022 Trigger a Third-year La Niña Event?显示文摘Based on the updates of the Climate Prediction Center and International Research Institute for Climate and Society(CPC/IRI)and the China Multi-Model Ensemble(CMME)El Niño-Southern Oscillation(ENSO)Outlook issued in April 2022,La Niña is favored to continue through the boreal summer and fall,indicating a high possibility of a three-year La Niña(2020-23).It would be the first three-year La Niña since the 1998-2001 event,which is the only observed three-year La Niña event since 1980.By examining the status of air-sea fields over the tropical Pacific in March 2022,it can be seen that while the thermocline depths were near average,the southeasterly wind stress was at its strongest since 1980.Here,based on a quaternary linear regression model that includes various relevant air-sea variables over the equatorial Pacific in March,we argue that the historic southeasterly winds over the equatorial Pacific are favorable for the emergence of the third-year La Niña,and both the anomalous easterly and southerly wind stress components are important and contribute~50%of the third-year La Niña growth,respectively.Additionally,the possible global climate impacts of this event are discussed. | Xianghui FANG Fei ZHENG Kexin LI Zeng-Zhen HU Hongli REN Jie WU Xingrong CHEN Weiren LAN Yuan YUAN Licheng FENG Qifa CAI Jiang ZHU | 2023 | Advances in Atmospheric Sciences2023，40，1： | 2 |
| 7 | Multiple pass-band optical left-handed metamaterials based on random dendritic cells显示文摘 | Liu Baoqi Zhao Xiaopeng Zhu Weiren | 2008 | Adv Funct Mater2008，18，： | 1 |
| 8 | Time-Modulated Transmissive Programmable Metasurface for Low Sidelobe Beam Scanning显示文摘Programmable metasurfaces have great potential for the implementation of low-complexity and low-cost phased arrays.Due to the difficulty of multiple-bit phase control,conventional programmable metasurfaces suffer a relatively high sidelobe level(SLL).In this manuscript,a time modulation strategy is introduced in the 1-bit transmissive programmable metasurface for reducing the SLLs of the generated patterns.After the periodic time modulation,harmonics are generated in each reconfigurable unit and the phase of the first-order harmonic can be dynamically controlled by applying different modulation sequences onto the corresponding unit.Through the high-speed modulation of the real-time periodic coding sequences on the metasurface by the programmable bias circuit,the equivalent phase shift accuracy to each metasurface unit can be improved to 6-bit and thus the SLLs of the metasurface could be reduced remarkably.The proposed time-modulated strategy is verified both numerically and experimentally with a transmissive programmable metasurface,which obtains an aperture efficiency over 34%and reduced SLLs of about-2o dB.The proposed design could offer a novel approach of a programmable metasurface framework for radar detection and secure communication applications. | Xudong Baio Fuli Zhang Li Sun Anjie Cao Jin Zhang Chong He Longhai Liu Jianquan Yao Weiren Zhu | 2022 | Research2022，，4： | 1 |
| 9 | Comprehensive analysis of complement-associated molecular features in hepatocellular carcinoma显示文摘The complement cascade plays a“complementing”role in human immunity.However,the potential roles of complement system in impacting molecular and clinical features of hepatocellular carcinoma(HCC)remain unclear.In this study,eleven public datasets are analyzed to compare the complement status between normal and cancerous samples based on 18 classical complement-associated genes.The complement scores are constructed to quantify complement signatures of individual tumors.HCC patients in the The Cancer Genome Atlas(TCGA)cohort are focused to perform systematical analyses between complement status and immune infiltration,miRNA expression,DNA methylation,clinicopathological features,and drug response.The results show that the complement scores in normal tissues are dramatically higher than those of tumor tissues.Tumor samples in the TCGA cohort are classified into complement score-low and score-high groups.Pathway analysis reveals that tumor-promoting pathways are typically inhibited in complement score-high group.This study also shows that tumor-killing immune cells,such as CD8^(+)T cells and natural killer cells are abundant and tumor-suppressing miRNAs are upregulated in complement score-high samples.In addition,we identify that complement scores are negatively correlated with certain clinical features,including pathological grade,clinical-stage,and portal vein invasion.Moreover,various molecular features together with complement scores are found to be correlated with response to anti-cancer drugs.This study provides a comprehensive and multidimensional analysis conducive to understanding the role of complement in cancer. | Run Huang Guiqi Zhu Xiutao Fu Weiren Liu Chenyang Tao Jun Gao Weifeng Qu Yuan Fang Xifei Jiang Zhenbin Ding Jian Zhou Yinghong Shi Jia Fan Zheng Tang | 2022 | Acta Biochimica et Biophysica Sinica2022，54，11： | 0 |
| 10 | Multiomics analysis reveals metabolic subtypes and identifies diacylglycerol kinase α (DGKA) as a potential therapeutic target for intrahepatic cholangiocarcinoma显示文摘Background:Intrahepatic cholangiocarcinoma(iCCA)is a highly heteroge-neous and lethal hepatobiliary tumor with few therapeutic strategies.The metabolic reprogramming of tumor cells plays an essential role in the develop-ment of tumors,while the metabolic molecular classification of iCCA is largely unknown.Here,we performed an integrated multiomics analysis and metabolic classification to depict differences in metabolic characteristics of iCCA patients,hoping to provide a novel perspective to understand and treat iCCA.Methods:We performed integrated multiomics analysis in 116 iCCA samples,including whole-exome sequencing,bulk RNA-sequencing and proteome anal-ysis.Based on the non-negative matrix factorization method and the protein abundance of metabolic genes in human genome-scale metabolic models,the metabolic subtype of iCCA was determined.Survival and prognostic gene analy-ses were used to compare overall survival(OS)differences between metabolic subtypes.Cell proliferation analysis,5-ethynyl-2’-deoxyuridine(EdU)assay,colony formation assay,RNA-sequencing and Western blotting were performed to investigate the molecular mechanisms of diacylglycerol kinaseα(DGKA)in iCCA cells.Results:Three metabolic subtypes(S1-S3)with subtype-specific biomarkers of iCCA were identified.These metabolic subtypes presented with distinct prog-noses,metabolic features,immune microenvironments,and genetic alterations.The S2 subtype with the worst survival showed the activation of some special metabolic processes,immune-suppressed microenvironment and Kirsten ratsar-coma viral oncogene homolog(KRAS)/AT-rich interactive domain 1A(ARID1A)mutations.Among the S2 subtype-specific upregulated proteins,DGKA was further identified as a potential drug target for iCCA,which promoted cell proliferation by enhancing phosphatidic acid(PA)metabolism and activating mitogen-activated protein kinase(MAPK)signaling.Conclusion:Viamultiomics analyses,we identified three metabolic subtypes of iCCA,revealing that the S2 subtype exhibited the poorest survival outcomes.We further identified DGKA as a potential target for the S2 subtype. | Weiren Liu Huqiang Wang Qianfu Zhao Chenyang Tao Weifeng Qu Yushan Hou Run Huang Zimei Sun Guiqi Zhu Xifei Jiang Yuan Fang Jun Gao Xiaoling Wu Zhixiang Yang Rongyu Ping Jiafeng Chen Rui Yang Tianhao Chu Jian Zhou Jia Fan Zheng Tang Dong Yang Yinghong Shi | 2024 | Cancer Communications2024，44，2： | 0 |
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