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| 1 | Psychosocial issues in evidence-based guidelines on inflammatory bowel diseases: A review显示文摘AIM:To study statements and recommendations on psychosocial issues as presented in international evidence-based guidelines on the management of inflammatory bowel diseases(IBD).METHODS:MEDLINE,guidelines International Network,National Guideline Clearing House and National Institute for Health and Care Excellence were searched from January 2006 to June 30,2013 for evidencebased guidelines on the management of IBD.RESULTS:The search yielded 364 hits.Thirteen guidelines were included in the review,of which three wereprepared in Asia,eight in Europe and two in the United States.Eleven guidelines made statements and recommendations on psychosocial issues.The guidelines were concordant in that mental health disorders and stress do not contribute to the aetiology of IBD,but that they can influence its course.It was recommended that IBD-patients should be screened for psychological distress.If indicated,psychotherapy and/or psychopharmacological therapy should be recommended.IBDcentres should collaborate with mental health care specialists.Tobacco smoking patients with Crohn’s disease should be advised to quit.CONCLUSION:Patients and mental health specialists should be able to participate in future guideline groups to contribute to establishing recommendations on psychosocial issues in IBD.Future guidelines should acknowledge the presence of psychosocial problems in IBD-patients and encourage screening for psychological distress. | Winfried Huser Gabriele Moser Petra Klose Antonina Mikocka-Walus | 2014 | World Journal of Gastroenterology2014,20,13: | 14 |
| 2 | Second European evidence-based consensus on the diagnosis and management of ulcerative colitis: Special situations显示文摘 | Gert Van Assche Axel Dignass Bernd Bokemeyer Silvio Danese Paolo Gionchetti Gabriele Moser Laurent Beaugerie Fernando Gomollón Winfried H?user Klaus Herrlinger Bas Oldenburg Julian Panes Francisco Portela Gerhard Rogler Jürgen Stein Herbert Tilg Simon Tra | 2012 | Journal of Crohn’s and Colitis2012,,: | 4 |
| 3 | Association of the GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer显示文摘AIM:To analyze the impact of the GNAS1 T393C polymorphism on prognosis and histopathology of gastric cancer.METHODS:Genomic DNA was extracted from paraffinembedded tissues of 122 patients with primary gastric carcinoma and from the blood of 820 healthy white individuals.Allelic discrimination was performed by quantitative real-time polymerase chain reaction.Genotyping was correlated with histopathologic parameters and with overall survival according to the Kaplan-Meier approach and with multivariate analysis by multiple stepwise regression.RESULTS:Thirty-nine(32%) patients displayed a CC genotype,57(46.7%) a CT genotype and 26(21.3%) a TT genotype.The frequency of the C allele(fC) in the patient group was 0.55,which was not signif icantly different from that of healthy blood donors.The distribution was compatible with the Hardy-Weinberg equilibrium.Analysis of clinicopathological parameters did not show any signif icant correlation of the T393C genotype with gender(P=0.50),differentiation(P=0.29),pT-category(P=0.19),pN-category(P=0.30),pM-category(P=0.25),R-category(P=0.95),the classifications according to WHO(P=0.34),Laurén(P=0.16),Goseki(P=1.00) and Ming(P=0.74).Dichotomization between C+(CC+CT) and C-genotypes(TT),however,revealed signif icantly more advanced tumor stages(P=0.023) and lower survival rates(P=0.043) for C allele carriers.CONCLUSION:The present study provides strong evidence to suggest that the GNAS1 T393C allele carrier status influences tumor progression and survival in gastric cancer with higher tumor stages and a worse outcome for C allele carriers. | Hakan Alakus Stefan P Mnig Ute Warnecke-Eberz Gül Alakus Günther Winde Uta Drebber Klaus J Schmitz Kurt W Schmid Kathrin Riemann Winfried Siffert Elfriede Bollschweiler Arnulf H Hlscher Ralf Metzger | 2009 | World Journal of Gastroenterology2009,15,48: | 3 |
| 4 | Right Portal Vein Ligation Combined With In Situ Splitting Induces Rapid Left Lateral Liver Lobe Hypertrophy Enabling 2-Staged Extended Right Hepatic Resection in Small-for-Size Settings显示文摘 | Andreas A. Schnitzbauer Sven A. Lang Holger Goessmann Silvio Nadalin Janine Baumgart Stefan A. Farkas Stefan Fichtner-Feigl Thomas Lorf Armin Goralcyk Rüdiger H?rbelt Alexander Kroemer Martin Loss Petra Rümmele Marcus N. Scherer Winfried Padberg Alfred K? | 2012 | Annals of Surgery2012,,3: | 2 |
| 5 | Thematic Data Processing on Board the Satellite BIRD显示文摘 | Winfried H | 2001 | Proceeding of SPIE2001,4540,: | 1 |
| 6 | Anterior cervical fusion with the Orion locking plate system 显示文摘 | Volkmar H Nikolai G Winfried B | 1998 | Spine1998,23,16: | 1 |
| 7 | Duplexes of 21-nucleotide RNAs mediate RNA interference in all cultured mammalian cells显示文摘 | Jens H Winfried L | 2001 | Nature2001,411,: | 1 |
| 8 | Variance vs downside risk:is there really that much difference?显示文摘 | Grootveld H Winfried H | 1999 | European Journal of Operational Research1999,114,: | 1 |
| 9 | Deep tissue two-photon microscopy显示文摘 | Fritjof H Winfried D | 2005 | Nat Methods2005,2,: | 1 |
| 10 | 'PV solar electricity industry:Market growth and per-spective,'显示文摘 | Winfried H | | 0,,18: | 1 |
| 11 | Interaction of the ACE D Allele and the GNB3 825T Allele in Myocardial Infarction显示文摘 | Christoph K. Naber Johannes Hüsing Ulrich Wolfhard Raimund Erbel Winfried Siffert | 2000 | Hypertension: Journal of the American Heart Association2000,,6: | 1 |
| 12 | Development and Validation of the Celiac Disease Questionnaire (CDQ), a Disease-specific Health-related Quality of Life Measure for Adult Patients With Celiac Disease显示文摘 | Winfried H?user Joachim Gold Andreas Stallmach Wolfgang F. Caspary Jürgen Stein | 2007 | Journal of Clinical Gastroenterology2007,,2: | 1 |
| 13 | Right Portal Vein Ligation Combined With In Situ Splitting Induces Rapid Left Lateral Liver Lobe Hypertrophy Enabling 2-Staged Extended Right Hepatic Resection in Small-for-Size Settings显示文摘 | Andreas A. Schnitzbauer Sven A. Lang Holger Goessmann Silvio Nadalin Janine Baumgart Stefan A. Farkas Stefan Fichtner-Feigl Thomas Lorf Armin Goralcyk Rüdiger H?rbelt Alexander Kroemer Martin Loss Petra Rümmele Marcus N. Scherer Winfried Padberg Alfred K? | 2012 | Annals of Surgery2012,,3: | 1 |
| 14 | Two-photon laser scanning fluorescence microscopy显示文摘 | Winfried D James H S and Watt W W | 1990 | science1990,248,: | 1 |
| 15 | The role of antidepres- sants in the management of fibromyalgia syndrome:a systematic re- view and meta-analysis 显示文摘 | Winfried H Frederick W Thomas T | 2012 | CNS Drugs2012,26,: | 1 |
| 16 | Virus membrane fusion 显示文摘 | Winfried W Andreas H Yves G | 2007 | FEBS Letters2007,581,: | 1 |
| 17 | Improved method for the preparative synthesis of labeled trehalose of high specific activity by escherichia coli显示文摘 | Reinhold H Ralf P Winfried B | 1996 | Applied and Environmental Microbiology1996,62,10: | 1 |
| 18 | Preclinical experiences with magnetic drug targeting: Tolerance and efficacy 显示文摘 | Andreas SL Chrcistain B Winfried H | 1996 | Cancer Res1996,,56: | 1 |
| 19 | Fluorine speciation and mobility in F-contaminated soils显示文摘 | Walter W Wenzel Winfried E H Blum | 1992 | Soil Science1992,153,5: | 1 |
| 20 | Safety of low-density lipoprotein reduction with atorvastatin versus simvastatin in a coronary heart disease population ( the TARGET TANGIBLE trial) 显示文摘 | Winfried M Wollschlager H Klein G Neib A Wehling M | 1999 | Am J Cardiol1999,84,: | 1 |