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| 1 | Experimental study of“Tong Xia”purgative method in ameliorating lung injury in acute necrotizing pancreatitis显示文摘AIM To investigate the role of tumor necrosisfactor(TNF)in lung injury during acutenecrotizing pancreatitis(ANP),and thetherapeutic effect of'Tong Xia'purgativemethod in minimizing the severity of lung injury.METHODS Fourteen canines were randomlydivided into 3 groups:the'Tong Xia'treatmentgroup(n = 5)using Dachengqitang;salinecontrol group(n = 5),and the sham operationgroup(n = 4).TNF activity in serum and inbronchoalveolar lavage fluid(BALF),the serumendotoxin levels were measured,and theseverity of lung injury evaluated.RESULTS Elevation of TNF activity was moreprominent in BALF than in serum.TNF activity inserum at 6 and 12 hours and in BALI:wassignificantly decreased in the'Tong Xia'treatment group than in the saline control one(q=21.11,q=12.07,q=9.03,respectively,P<0.01)and the lung injury was significantlyalleviated at 12 hours as compared with that inthe saline group,manifested as amelioration otthe lung wet/ dry weight ratio,decrease inprotein concentration and neutrophils count inBALF,and improvement of pulmonaryinflammatory changes.A positive correlationwas demonstrated between serum TNF activity and endotoxin level.CONCLUSION Hypersecretion of TNF is shownto be one of the major causes of lung injuryduring ANP;'Tong Xia'purgative method couldalleviate the degree of lung injury mediated byTNF. | Xia Q Jiang JM Gong X Chen GY Li L Huang ZW | 2000 | World Journal of Gastroenterology2000，6，1： | 31 |
| 2 | Long-term fertilizer effects on organic carbon and total nitrogen and coupling relationships of C and N in paddy soils in subtropical China显示文摘 | Tong CL Xiao HA Tang GY Wang HQ Huang TP Xia HA Keith S J Li Y Liu SL Wu JS | 2009 | Soil and Tillage Research2009，106，1： | 1 |
| 3 | Mstl and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yapl oncogene显示文摘 | Zhou D Conrad C Xia F Park JS Payer B Yin Y Lauwers GY Thasler W Lee JT Avruch J Bardeesy N | 2009 | Cancer Cell2009，16，5： | 1 |
| 4 | Proteomic analy- sis of rat retina after methanol intoxication显示文摘 | Chen JM Zhu GY Xia WT | 2012 | Toxi- cology2012，293，13： | 1 |
| 5 | Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling显示文摘 | Chert YJ Shi GY Xia W | 2004 | Cancer Res2004，64，： | 1 |
| 6 | Association of insulin gene rariable number of tandem repeats regulatory polymorphism vith polyeystic ovary syndrome 显示文摘 | Yan MS Liang GY Xia BR | 2014 | Hum Immunol2014，7510，： | 1 |
| 7 | The effect of bioequivalent radiation dose on survival of patients with limited-stage small cell lung cancer显示文摘 | XIA B CHEN GY CAI XW | 2011 | Radiat Oncol2011，19，6： | 1 |
| 8 | Phosphorus fractions and alkaline phosphataseactivity in sediments of a large eutrophic Chinese lake(Lake Taihu) 显示文摘 | Zhou YY Song CL Cao XY Li JQ Chen GY Xia ZY Jiang PH | 2008 | Hydrobiologia2008，599，： | 1 |
| 9 | Changes in IP3R1 and SERCA2b mRNA levels in the gerbil brain after chronic ethanol administration and transient cerebral ischemia-reperfusion 显示文摘 | Xia J Simonyi A Sun GY | 1998 | Brain Res Mol Brain Res1998，56，12： | 1 |
| 10 | Imaging diagnosis of gastrointesti- nal stromal tumors (GIST):twelve case analysis显示文摘 | Xia YB Wu M Liu GY | 2002 | Chin J Med Imaging Technol2002，18，1： | 1 |
| 11 | Two splicing variants of a novel family of octopamine receptors with different signaling properties显示文摘 | Wu SF Xu G Qi XY Xia RY Huang J Ye GY | | 0，，： | 1 |
| 12 | Aegilops tauschii draft genome sequence reveals a gene repertoire for wheat adaptation显示文摘 | Jia J Zhao SC Kong XY Li YR Zhao GY He WM Appels RD Pfeifer M Tao Y Zhang XY Jing RL Zhang C Ma YZ Gao LF Gao C Spannagl M Mayer KFX Li D Pan SK Zheng FY Hu Q Xia XC Li JW Liang QS Chen J Wicker T Gou CY Kuang HH He GY Luo YD Keller B Xia QJ Lu P Wang JY | | 0，，： | 1 |
| 13 | The effect of bioequivalent radia tion dose on survival of patients with limited-stage small-cell lung cancer显示文摘 | Xia B Chen GY Cai XW | 2011 | Radiat Oncol2011，6，： | 1 |
| 14 | Identification of hypoxia-regulation proteins in head and neck cancer by proteomic and tissue array profiling显示文摘 | Chen YJ Shi GY Xia W | 2004 | Cancer Res2004，64，20： | 1 |
| 15 | Proteomic analysis of rat reti- na after methanol intoxication显示文摘 | Chen JM Zhu GY Xia WT | 2012 | Toxicology2012，293，13： | 1 |
| 16 | Is involved-field radiotherapy based on CT safe for patients with limited-stage small-cell lung cancer?显示文摘 | Xia B Chen GY Cai XW | 2012 | Radiother Oncol2012，102，2： | 1 |
| 17 | Effect of rat brain tissue extracts on osteoblast proliferation and differentiation显示文摘 | Huang GY Ma X Xia XL | 2012 | Int Ortho2012，36，4： | 1 |
| 18 | Antioxidative activity of Ganoderma lucidum polysaccharide显示文摘 | Dong FL Xia GY Xiong ZK | 2010 | J Tradit Med Information2010，2，2： | 1 |
| 19 | Identification of hypoxia-reg- ulated proteins in head and neck cancer by proteomic and tissuearray profiling显示文摘 | CHEN Y J SHI GY XIA W | 2004 | Cancer Res2004，64，： | 1 |
| 20 | Clinical study on the treatment of severe acute pancreatitis by integrated traditional Chinese medicine and Western medicine显示文摘 | Liu XB Jiang JM Huang ZW Tian BL Hu WM Xia Q Chen GY Li QS Yuan CX Luo CX Yan LN Zhang ZD | 2004 | Sichuan Daxue Xuebao Yixueban2004，35，： | 1 |
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