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1Injectable hydrogels for cartilage and bone tissue engineering显示文摘Tissue engineering has become a promising strategy for repairing damaged cartilage and bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels have demonstrated great potential for use as three-dimensional cell culture scaffolds in cartilage and bone tissue engineering, owing to their high water content, similarity to the natural extracellular matrix(ECM), porous framework for cell transplantation and proliferation, minimal invasive properties, and ability to match irregular defects. In this review, we describe the selection of appropriate biomaterials and fabrication methods to prepare novel injectable hydrogels for cartilage and bone tissue engineering. In addition, the biology of cartilage and the bony ECM is also summarized. Finally, future perspectives for injectable hydrogels in cartilage and bone tissue engineering are discussed.Mei Liu Xin Zeng Chao Ma Huan Yi Zeeshan Ali Xianbo Mou Song Li Yan Deng Nongyue He 2017Bone Research2017,5,2:54
2国内外油田含油污泥处理技术显示文摘通过对国内外各种含油污泥处理工艺技术的调查分析和对比,提出了适合国内实际的含油污泥处理技术方案。以离心分离技术为核心,辅之以调质、倾析等多种预处理技术和高温裂解、生物处理等后续处理技术的污泥综合处理工艺,适于我国现阶段的含油污泥处理。Yin Xianbo (Daqing Oilfield Engineering Co.Ltd) 2007油气田环境保护2007,17,3:34
3Multiresidue determination and potential risks of emerging pesticides in aquatic products from Northeast China by LC-MS/MS显示文摘A simple method for determining 33 pesticides with a wide polarity range(log Kow0.6-4.5) in aquatic products was developed based on LC–MS/MS. The target analytes included three types of widely used pesticides: insecticides, fungicides and herbicides. Based on the optimization of ultrasonic assisted extraction and GPC clean-up procedures, the matrix effect, extraction recoveries and LOD were improved distinctively. LOQ of this method was below 0.5 ng/g for all pesticides, which is superior to values in the literature, and the matrix effect was reduced effectively(-14.7% to 7.5%). The method was successfully applied to investigate the pesticide residue levels of twenty-five samples including seven common kinds of fishes from Northeast China. The results showed that all targeted pesticides were present in the fish samples; however, their levels were low, except for atrazine, linuron,ethoprophos, tetrachlorvinphos, acetochlor and fenthion. Atrazine and linuron caught our attention because the concentrations of atrazine in fish samples from Liaoning province were in the range of 0.5-8 ng/g(w/w) with mean concentration of 2.3 ng/g, which were far above those of other pesticides. The levels of linuron were in the range of 0.6-6 ng/g(mean concentration 2.8 ng/g), which were the highest among all targeted pesticides in the Inner Mongolia. This is the first systematic investigation on the characteristics and levels of these pesticides in aquatic products from northeast China. Considering their toxicity and bioaccumulation, the potential risk of atrazine and linuron from consuming aquatic products should be paid more attention.Lei Fu Xianbo Lu Jun Tan Longxing Wang Jiping Chen 2018Journal of Environmental Sciences2018,30,1:17
4A finite element modeling of posterior atlantoaxial fixation and biomechanical analysis of C2 intralaminar screw fixation显示文摘Ma Xuexiao Peng Xianbo Xiang Hongfei Zhang Yan Zhang Guoqing Chen Bohua 2014Chinese Medical Journal2014,,7:15
5Structure of the organic crystallite unit in coal as determined by X-ray diffraction显示文摘X-ray diffraction (XRD) was used to study the structure of the organic crystallite unit (La, Lc, d002) in coals collected from Henan and Shanxi Provinces. XRD patterns of coal were collected in a step-scan mode (0.1°/step) over an angular range of 2-90° (2h), allowing 8 s at each step. The structure of the crystallite unit was determined from the Scherrer equation and peak parameters deduced from whole pattern fit- ting. The results show that the structure of the crystallite unit in coal is mainly controlled by the coal rank. As the coal rank increases the average diameter of a coal crystallite unit (La) increases, the inter- layer spacing (d002) decreases slightly, and the average height of a coal crystallite unit (Lc) increases at first but then decreases. A new diffraction peak from the crystallite unit in coal was found at a low scat- tering angle in the XRD pattern (2-10°). This suggests a structure with an inter-layer spacing from 1.9 to 2.8 nm exists in coal crystallites.Song Dangyu Yang Cunbei Zhang Xiaokui Su Xianbo Zhang Xiaodong 2011Mining Science and Technology2011,21,5:12
6Electrolytic reduction of mixed solid oxides in molten salts for energy efficient production of the TiNi alloy显示文摘Direct electrochemical reduction of mixed TiO2 and NiO powders to TiNi alloy has been successfully demonstrated in molten CaCl2 at 900℃ by constant voltage electrolysis. The electrolysis en- ergy consumption was as low as 23.4 kWh/kg-TiNi, although the current efficiency was 20.5% in the pre- liminary experiments. During the process, NiO was first reduced to Ni at high speed, accompanied by TiO2 being perovskitized to CaTiO3?x which was gradually reduced to Ni3Ti and TiNi, assisted by the depolarization of the preformed Ni. The cell voltage for preparation of the TiNi alloy was lower than that for Ti. Adjusting the cell voltage not only affected the reduction speed, but also offered a convenient ac- cess to the preparation of the nickel/perovskite composite.ZHU Yong MA Meng WANG Dihua JIANG Kai HU Xiaohong JIN Xianbo George Z. CHEN 2006Chinese Science Bulletin2006,51,20:11
7Analysis of 2D Flow and Heat Transfer Modeling in Fracture of Porous Media显示文摘Heat and mass transfer between porous media and fluid is a complex coupling process, which is widely used in various fields of engineering applications, especially for natural and artificial fractures in oil and gas extraction. In this study, a new method is proposed to deal with the flow and heat transfer problem of steady flow in a fracture. The fluid flow in a fracture was described using the same method as Mohais, who considered a fracture as a channel with porous wall, and the perturbation method was used to solve the mathematical model. Unlike previous studies, the shear jump boundary condition proposed by Ochoa-Tapia and Whitaker was used at the interface between the fluid and porous media. The main methods were perturbation analysis and the application of shear jump boundary conditions. The influence of permeability, channel width, shear jump degree and effective dynamic viscosity on the flow and heat transfer in the channel was studied by analysing the analytical solution. The distribution of axial velocity in the channel with the change of the typical parameters and the sensitivity of the heat transfer was obtained.GUO Chunsheng NIAN Xianbo LIU Yong QI Chao SONG Jinsheng YU Wenhe 2017Journal of Thermal Science2017,26,4:9
8Combination of iTRAQ proteomics and RNA-seq transcriptomics reveals multiple levels of regulation in phytoplasma-infected Ziziphus jujuba Mill显示文摘Jujube witches’broom(JWB)is caused by infection with a phytoplasma.A multi-omics approach was taken during graft infection of jujube by JWB-infected scion through the analysis of the plant transcriptome,proteome and phytohormone levels.A high number of differentially expressed genes(DEGs)were identified 37 weeks after grafting(WAG),followed by observation of typical symptoms of JWB at 48 WAG.At 37 WAG,the majority of the upregulated DEGs and differentially expressed proteins(DEPs)were related to flavonoid biosynthesis,phenylalanine metabolism and phenylpropanoid biosynthesis.Two of the four upregulated proteins were similar to jasmonate-induced protein-like.Among the downregulated genes,the two most populated GO terms were plant–pathogen interaction and plant hormone signal transduction(mainly for tryptophan metabolism).Moreover,phytoplasma infection resulted in reduced auxin content and increased jasmonate content,indicating that auxin and jasmonic acid have important roles in regulating jujube responses during the first and second stages of phytoplasma infection.At 48 WAG,the two largest groups of upregulated genes were involved in phenylpropanoid biosynthesis and flavonoid biosynthesis.Both genes and proteins involved in carbon metabolism and carbon fixation in photosynthetic organisms were downregulated,indicating that photosynthesis was affected by the third stage of phytoplasma infection.Xia Ye Huiyu Wang Peng Chen Bing Fu Mengyang Zhang Jidong Li Xianbo Zheng Bin Tan Jiancan Feng 2017Horticulture Research2017,4,1:9
9Genomic sequencing and analysis of the first imported Middle East Respiratory Syndrome Coronavirus(MERS CoV) in China显示文摘Dear Editors,Middle East Respiratory Syndrome(MERS)has spread to more than 23 countries since the first case of a MERS coronavirus(MERS Co V)infection was confirmed in Sep2012[1].Because MERS Co V has led to mortality as high as 40%,it has become one of the most important emerging pathogens threatening human health.Recently,the outbreak of MERS Co V,which resulted in 172 infections andXIE Qian CAO YuJuan SU Juan WU XianBo WAN ChengSong KE ChangWen ZHAO Wei ZHANG Bao 2015Science China(Life Sciences)2015,58,8:8
10Microbial corrosion resistance of a novel Cu-bearing pipeline steel显示文摘Microbiologically influenced corrosion(MIC) is becoming a serious problem for buried pipelines. Developing environmentally friendly strategies for MIC control is increasingly urgent in oil/gas pipeline industry.Copper(Cu) in steels can not only provide aging precipitation strengthening, but also kill bacterium,offering a special biofunction to steels. Based on the chemical composition of traditional X80 pipeline steel, two Cu-bearing pipeline steels(1% Cu and 2% Cu) were fabricated in this study. The microstructure,mechanical properties and antibacterial property against sulphate-reducing bacteria(SRB) and Pseudomonas aeruginosa(P. aeruginosa) were studied. It was found that the novel pipeline steel alloyed by 1%Cu exhibited acicular ferrite microstructure with nano-sized Cu-rich precipitates distribution in the matrix, resulting in better mechanical properties than the traditional X80 steel, and showed good MIC resistance as well. The pitting corrosion resistance of 1% Cu steel in as-aged condition was significantly better than that of X80 steel. A possible antibacterial mechanism of the Cu-bearing pipeline steel was proposed.Xianbo Shi Wei Yan Dake Xu Maocheng Yan Chunguang Yang Yiyin Shan Ke Yang 2018Journal of Materials Science & Technology2018,34,12:7
11Piperlongumine Inhibits Zika Virus Replication In vitro and Promotes Up-Regulation of HO-1 Expression, Suggesting An Implication of Oxidative Stress显示文摘Owing to the widespread distribution of mosquitoes capable of transmitting Zika virus, lack of clinical vaccines and treatments, and poor immunity of populations to new infectious diseases, Zika virus has become a global public health concern. Recent studies have found that Zika virus can continuously infect human brain microvascular endothelial cells.These cells are the primary components of the blood–brain barrier of the cerebral cortex, and further infection of brain tissue may cause severe damage such as encephalitis and fetal pituitary disease. The present study found that a biologically active base, piperlongumine(PL), inhibited Zika virus replication in human brain microvascular endothelial cells, Vero cells, and human umbilical vein endothelial cells. PL also significantly increased heme oxygenase-1(HO-1) gene expression, while silencing HO-1 expression and using the reactive oxygen species scavenger, N-acetylcysteine, attenuated the inhibitory effect of PL on Zika virus replication. These results suggest that PL induces oxidative stress in cells by increasing reactive oxygen species. This, in turn, induces an increase in HO-1 expression, thereby inhibiting Zika virus replication. These findings provide novel clues for drug research on the prevention and treatment of Zika virus.Weizhi Lu Linjuan Shi Jing Gao Huimin Zhu Ying Hua Jintai Cai Xianbo Wu Chengsong Wan Wei Zhao Bao Zhang 2021Virologica Sinica2021,36,3:4
12In-situ Synthesis of ZSM-5 Zeolite from Metakaolin/Spinel and Its Catalytic Performance on Methanol Conversion显示文摘ZSM-5 zeolite was in-situ synthesized from metakaolin or spinel by incorporating additional silica and alumina sources,respectively.The ZSM-5 zeolite was characterized by X-ray diffractometry(XRD),scanning electron microscopy(SEM),Fourier transform infrared(FT-1R) spectroscopy and N_2 adsorption measurement. This supported zeolite was tested on the methanol to propylene(MTP) processes.Experimental results showed that the ZSM-5 zeolite exhibited high selectivity for propylene.The yield of propylene on ZSM-5 zeolite made from metakaolin was increased by 17.73%,while that on ZSM-5 zeolite made from spinel was raised by 9.90%,compared to that achieved with the commercial ZSM-5 zeolite.The significant increase in propylene production is probably due to the distinctive morphology of the ZSM-5 zeolite,which possessed a rough external surface covered with sphere-like particles and distribution of small crystals sized at around 400—500 nm.This morphology could help to generate more crystal defects so that more active centers could be exposed to the reaction mixture.In addition,the zeolite product had a gradient pore distribution and many medium Bronsted acid sites,both of which might also contribute to the increased propylene production.Liu Ye Yu Xianbo Qin Lei Wang Jingdai Yang Yongrong (Department of Chemical and Biochemical Engineering,Zhejiang University,Hangzhou 310027) 2010China Petroleum Processing & Petrochemical Technology2010,12,1:4
13Bisphenol-A epoxy resin reinforced and toughened by hyperbranched epoxy resin显示文摘The study on toughening and reinforcing of bisphenol-A epoxy resin is one of important developmental direction in the field.This paper reports a one-pot synthesis of aromatic polyester hyperbranched epoxy resin HTDE-2,an effect of HTDE-2 content on the mechanical and thermal performance of the bisphenol-A(E51)/HTDE-2 hybrid resin in detail.Fourier transform infrared(FT-IR)spectrometer,scanning electronic microscopy(SEM),differential scanning calo ri metry(DSC),thermogravimetric analysis(TGA),dynamic mechanical thermal analysis(DMA)and molecular simula tion technology are used to study the structure of HTDE-2,performance and toughening and reinforcing mech-anism of the HTDE-2/E51 hybrid resin.It has been shown that the content of HTDE-2 has an important effect on the performance of the hybrid resin,and the performance of the HTDE-2/E51 blends has maximum with the increase in HTDE-2 content.The impact strength and fracture toughness of the hybrid resin with 9 wt-%HTDE-2 are almost 3.088 and 1.749 times of E51 performance respectively,furthermore,the tensile and flexural strength can also be enhanced about 20.7% and 14.2%,respectively.The glass transition tem-perature and thermal degradation temperature,however,are found to decrease to some extent.ZHANG Daohong JIA Demin HUANG Xianbo 2007Frontiers of Chemical Science and Engineering2007,1,4:3
14High surface area, high catalytic activity titanium dioxide aerogels prepared by solvothermal crystallization显示文摘Titanium dioxide has been considered to be one of the most effective and environmental friendly photocatalytic material.It has been widely used in photocatalytic degradation of various pollutants.As we known,an anatase crystal form typically obtained by high temperature heat treatment(>600℃),usually shows higher catalytic activity.In order to further improve the catalytic efficiency,we prepared TiO2 with a non-supercritical drying method to form a high specific surface area aerogel structure,along with an increased active contact site.However,with the inevitable of internal pores collapse in the process of high temperature crystallization,a large amount of porous structure and specific surface area is reduced.Here,to enhance the photocatalytic activity of titania,we propose a synergistic strategy to fabricate a porous titania structure with a high specific surface area.It was crystallized at a lower temperature(120℃) in a low-boiling solvent(ethanol,acetone,etc.).The lattice structure was identified by X-ray diffractometry;specific surface area(over 300 m2/g) of our sample was also measured through BET test;in the subsequent photocatalytic degradation test,the photocatalytic degradation efficiency of fabricated TiO2 is proved to be more excellent than P25 powder.By a freeze-drying/mild crystallization method,a high-specific surface area and high catalytic activity TiO2 aerogel was synthetized.This study provides some insights in the combining of crystallization and high specific surface area of titanium dioxide photocatalysis.Xian Yue Junhui Xiang Junyong Chen Huaxin Li Yunsheng Qiu Xianbo Yu 2020Journal of Materials Science & Technology2020,47,12:2
15Environmental and energy gains from using molten magnesium–sodium–potassium chlorides for electro-metallisation of refractory metal oxides显示文摘The molten eutectic mixture of magnesium,sodium and potassium chlorides(Mg Cl2–Na Cl–KCl) has inappreciable solubility for oxide ions,and can help disengage a carbon anode from the oxide ions generated at a metal oxide cathode,and effectively avoid carbon dioxide formation.This 'disengaging strategy' was successfully demonstrated in electro-reduction of solid oxides of zirconium and tantalum.It has led to significantly higher current efficiency(93%),and lower energy consumption(1.4 k W h kg 1) in electrolysis of tantalum oxide to tantalum metal compared to the conventional electrolysis in molten calcium chloride(e.g.78% and 2.4 k W h/kg-Ta).Wei Li Yating Yuan Xianbo Jin Hualin Chen George Z.Chen 2015Progress in Natural Science:Materials International2015,25,6:2
16The key stage and moment of coalbed gas reservior evolution in the Qinshui Basin,China显示文摘The evolution of coalbed gas reservoir is characterized by coalbed gas geochemistry and gas content. On the basis of burial history and thermal history, the forming process of coalbed gas reservoir and the gas accumulative history in the Qinshui Basin are discussed in this paper. The difference of the thermal history, geochemistry characteristic, and gas accumulative history between Yangcheng and Huozhou areas shows that the formation of coalbed gas reservoir in the Qinshui Basin is controlled by the geological process in the critical stage and the critical moment. The components and isotopes of coalbed methane are determined by the stage at which the coal maturation reaches its maximum rank. The coalbed methane accumulative history is related to the temperature and pressure of the coal burial history, because the coalbed gas is mainly in adsorptive state. It is stated that the gas content in the coal seam is controlled by the moment when the coal seam is uplifted to the shallowest position.ZHAO Mengjun SONG Yan SU Xianbo LIU Shaobo QIN Shengfei HONG Feng LIN Xiaoying 2005Chinese Science Bulletin2005,50,S1:2
17The abnormal pressure regime of the Pennsylvanian No. 8 coalbed methane reservoir in Liulin–Wupu District, Eastern Ordos Basin, China显示文摘Xianbo Su Liping Zhang Ruilin Zhang 2003International Journal of Coal Geology2003,,4:2
18A functional hyperbranched binder enabling ultra-stable sulfur cathode for high-performance lithium-sulfur battery显示文摘Binders are of vital importance in stabilizing the cathodes to enhance the cycling stability of lithiumsulfur(Li-S) batteries. However, conventional binders are typically confronted with the drawback of inability for adsorbing lithium polysulfide(Li PS), thus resulting in severe active material losing and rapid capacity fading. Herein, a novel water-soluble hyperbranched poly(amidoamine)(HPAA) binder with controllable hyperbranched molecular structure and abundant amino end groups for Li-S battery is designed and fabricated, which can improve efficient adsorption for Li PS and stability of the sulfur cathodes. Besides, the strong intermolecular hydrogen bonds in HPAA binder can contribute to the structural stability of S cathode and integration of the conductive paths. Therefore, the Li-S battery with this functional binder exhibits excellent cycle performance with a capacity retention of 91% after 200 cycles at 0.1 C.Even at a high sulfur loading of 5.3 mg cm-2, a specific capacity of 601 mA h g-1 can also be achieved.Density functional theory(DFT) calculation further demonstrates that the enhanced electrochemical stability derives from the high binding energy between amino groups and LiP S and the wide electrochemical window(6.87 e V) of HPAA molecule. Based on the above all, this functional polymer will lighten a new species of binders for eco-friendly sulfur cathodes and significantly promote the practical applications of high-performance Li-S batteries.Xiang Luo Xianbo Lu Xiaodong Chen Ya Chen Chunyang Yu Dawei Su Guoxiu Wang Lifeng Cui 2020Journal of Energy Chemistry2020,29,11:2
19Synthesis of aptamer-functionalized Ag nanoclusters for MCF-7 breast cancer cells imaging显示文摘Aptamer-functionalized silver nanoclusters(Ag NCs) have been attracting a lot of interest as label-free probes which have been successfully applied to both cell imaging and molecular detection.MUCl aptamer is an ssDNA aptamer that specifically binds to MUCl mucin which is a large transmembrane glycoprotein whose expression level increases at least 10-fold in primary and metastatic breast cancers.Using C4A4C3-linker-MUCl as template,the Ag NCs were synthesized through one-pot process.The fluorescence intensity of Ag NCs was found to be closely related to the length and type(poly adenine or thymine) of the linker,the optimum linker being-AAAAA-.Using the C4A4C3-A5-MUC1 as the scaffold,the synthesized Ag NCs emitted fluorescence with high quantum yield(QY) of 66.5%.Based on the specific interaction between the MUCl aptamer and MUCl mucin,the C4A4C3-A5-MUC1-stabilized Ag NCs could recognize and differentiate the MCF-7 breast cancer cells from MDA-MB-231 breast cancer and A549 human lung cancer cells.Taotao Li Jingjing Yang Zeeshan Ali Zunliang Wang Xianbo Mou Nongyue He Zhifei Wang 2017Science China Chemistry2017,60,3:2
20Irrigation-induced pollution of organochlorine pesticides and polychlorinated biphenyls in paddy field ecosystem of Liaohe River Plain,China显示文摘In order to assess the influence of long-term irrigation of polluted river water on the ecological health of the rice fields in the low reach of Liaohe River Plain,a series of environmental samples and biological samples in rice fields,including sediments,paddy soils,mitten-handed crabs(Eriocheir sinensis),loaches(Misgurnus anguillicaudatu) and frog(Hoplobatrachus tigerinus),were collected from the area far away from industrial zones,and polychlorinated biphenyls(PCBs) and organochlorine pesticides(HCH,DDT,HCB and Mirex) were analyzed by high resolution gas chromatography coupled with high resolution mass spectrometry(HRGC/HRMS).The comparison of pollutant concentrations and profiles verified that the significant contribution of river water irrigation to PCBs contaminations in paddy soils and the mutual influence of organochlorine pesticide contamination between river sediments and paddy soils.Bioaccumulations of PCBs and organochlorine pesticides in mitten-handed crabs and loaches were site-specific,suggested that they were both the good indicators of ecosystem health.Mitten-handed crabs had the highest capacity to accumulate PCBs and organochlorine pesticides,and also they had the strong ability to degrade these pollutants in their bodies,especially for DDT and HCH.The biota-soil accumulation factors(BSAF) of ΣH CH,ΣDDT,Mirex,HCB and ΣP CBs in mitten-handed crab were calculated to be 24.5,15.3,122.2,28.1 and 54.6,respectively.In view of the strong bioaccumulation ability,the health risk should be concerned for the cultivation of mitten-handed crabs in paddy fields in the low reach of Liaohe River Plain.TENG Man ZHANG HaiJun FU Qiang LU XianBo CHEN JiPing WEI FuSheng 2013Chinese Science Bulletin2013,58,15:2
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