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| 1 | Characteristics of δ^(18)O in precipitation over Eastern Monsoon China and the water vapor sources显示文摘Monsoon circulation is an important carrier of water vapor transport, and it impacts the precipitation of the monsoonal regions through the constraints and controls of large-scale water vapor transport and distributions as well as the water vapor balance. An overall research on stable Hydrogen and Oxygen isotopes in precipitation over Eastern Monsoon China could benefit a comprehensive understanding of the monsoonal precipitation mechanism. Seventeen field stations of the Chinese Network of Isotopes in Precipitation (CHNIP) have been selected to collect monthly composite precipitation samples during the years 2005―2006. Components of δ D and δ 18O have been analyzed to achieve the spatiotemporal distributions. The established Local Meteoric Water Line δ D=7.46δ 18O+0.90 based on the 274 obtained monthly samples could be treated as isotope input functions across the region, due to basically reflecting the specific regional meteorological conditions over Eastern Monsoon China. The δ-value depleted from coastal to inner area. In Southern China and Northeastern China there were typical periodic patterns of δ18O. Different dominant affecting metrological factors have been raised with different regions. From south to north, the temperature effect of δ18O enhanced, while the amount effect changed from existing at an all-year-scale in Southern China to being only remarkable during the main rainy seasons in North China and Northeastern China. Main geographical controls varied from altitude in Southern China and North China to latitude in Northeastern China. Furthermore, δ18O had an implication of advance and retreat of the monsoon as well as rainfall belt transfer. δ 18O was also a tracer for the movement path of typhoon and tropical storms. | LIU JianRong SONG XianFang YUAN GuoFu SUN XiaoMin LIU Xin | 2010 | Chinese Science Bulletin2010，55，2： | 40 |
| 2 | Stable isotopes of summer monsoonal precipitation in southern China and the moisture sources evidence from δ^18O signature显示文摘Summer monsoons (South Asian monsoon,South China Sea monsoon and Sub-tropical monsoon) are prominent features of summertime climate over southern China. Dif-ferent monsoons carry different inflow moisture into China and control the temporal and spa-tial distributions of precipitation. Analyses of meteorological data,particularly wind,tempera-ture and pressure anomalies are traditional methods of characterizing moisture sources and transport patterns. Here,we try to utilize the evidence from stable isotopes signatures to trace summer monsoons over southern China. Based on seven CHNIP (Chinese Network of Iso-topes in Precipitation) observatory stations located in southern China,monthly composite precipitation samples have been collected and analyzed for the composition of δ18O during July,2005. The results indicated that the spatial distributions of δ18O in precipitation could properly portray the moisture sources together with their transport pathways. Moreover,the amount effect,altitude effect,temperature effect and the correlation between δ18O vs. relative humidity were discussed. | LIU Jianrong SONG Xianfang YUAN Guofu SUN Xiaomin LIU Xin WANG Zhimin WANG Shiqin | 2008 | Journal of Geographical Sciences2008，18，2： | 15 |
| 3 | Saliency guided local and global descriptors for effective action recognition显示文摘This paper presents a novel framework for human action recognition based on salient object detection and a new combination of local and global descriptors. We first detect salient objects in video frames and only extract features for such objects.We then use a simple strategy to identify and process only those video frames that contain salient objects. Processing salient objects instead of all frames not only makes the algorithm more efficient, but more importantly also suppresses the interference of background pixels. We combine this approach with a new combination of local and global descriptors, namely3D-SIFT and histograms of oriented optical flow(HOOF), respectively. The resulting saliency guided3D-SIFT–HOOF(SGSH) feature is used along with a multi-class support vector machine(SVM) classifier for human action recognition. Experiments conducted on the standard KTH and UCF-Sports action benchmarks show that our new method outperforms the competing state-of-the-art spatiotemporal feature-based human action recognition methods. | Ashwan Abdulmunem Yu-Kun Lai Xianfang Sun | 2016 | Computational Visual Media2016，2，1： | 9 |
| 4 | Potassium 2-(1-hydroxypentyl)-benzoate attenuates neuronal apoptosis in neuron–astrocyte co-culture system through neurotrophy and neuroinflammation pathway显示文摘Potassium 2-(1-hydroxypentyl)-benzoate(D,L-PHPB), a new drug candidate for ischemic stroke at the phase II clinic trial, has been shown to protect neurons by inhibiting oxidative injury and reducing neuron apoptosis in previous studies. But the mechanisms of D,L-PHPB remain to be studied.In this study, a neuron–astrocytes co-culture system was used to elucidate the roles of astrocytes in neuroprotection of D,L-PHPB under oxygen-glucose deprivation/reoxygenation(OGD/R) condition. Our data showed that D,L-PHPB reduced neuronal apoptosis in mono-culture system and this effect was enhanced in neuron–astrocyte co-culture system under the OGD/R condition. Meanwhile, D,L-PHPB obviously increased the levels of brain-derived neurotrophic factor(BDNF) and nerve growth factor(NGF), which were mainly secreted from astrocytes, in the co-culture system after OGD/R. The PI3K/AKT and ERK signaling pathways as well as the p-TRKA/B receptors were involved in the process. In addition, the levels of TNF-α and IL-1β secreted from astrocytes after OGD/R were markedly reduced after D,L-PHPB treatment, which was mainly due to the suppression of phosphorylated p38. In conclusion, the present study demonstrates that the neuroprotective effects of D,L-PHPB were improved by astrocytes, mainly mediated by increasing the release of BDNF/NGF and attenuating inflammatory cytokines. | Dongmei Liu Man Zhang Xianfang Rong Jiang Li Xiaoliang Wang | 2017 | Acta Pharmaceutica Sinica B2017，7，5： | 8 |
| 5 | Field scale interaction and nutrient exchange between surface water and shallow groundwater in the Baiyang Lake region,North China Plain显示文摘Fertilizer input for agricultural food production, as well as the discharge of domestic and industrial water pollutants, increases pressures on locally scarce and vulnerable water resources in the North China Plain. In order to:(a) understand pollutant exchange between surface water and groundwater,(b) quantify nutrient loadings, and(c) identify major nutrient removal pathways by using qualitative and quantitative methods, including the geochemical model PHREEQC) a one-year study at a wheat(Triticum aestivum L.) and maize(Zea mays L.) double cropping system in the Baiyang Lake area in Hebei Province, China, was undertaken. The study showed a high influence of low-quality surface water on the shallow aquifer. Major inflowing pollutants into the aquifer were ammonium and nitrate via inflow from the adjacent Fu River(up to 29.8 mg/L NH4-N and 6.8 mg/L NO3-N), as well as nitrate via vertical transport from the field surface(up to 134.8 mg/L NO3-N in soil water). Results from a conceptual model show an excess nitrogen input of about 320 kg/ha/a. Nevertheless,both nitrogen species were only detected at low concentrations in shallow groundwater,averaging at 3.6 mg/L NH4-N and 1.8 mg/L NO3-N. Measurement results supported by PHREEQC-modeling indicated cation exchange, denitrification, and anaerobic ammonium oxidation coupled with partial denitrification as major nitrogen removal pathways. Despite the current removal capacity, the excessive nitrogen fertilization may pose a future threat to groundwater quality. Surface water quality improvements are therefore recommended in conjunction with simultaneous monitoring of nitrate in the aquifer, and reduced agricultural N-inputs should be considered. | Bentje Brauns Poul L.Bjerg Xianfang Song Rasmus Jakobsen | 2016 | Journal of Environmental Sciences2016，28，7： | 6 |
| 6 | Identification of key factors governing chemistry in groundwater near the water course recharged by reclaimed water at Miyun County, Northern China显示文摘Reclaimed water was successfully used to recover the dry Chaobai River in Northern China, but groundwater may be polluted. To ensure groundwater protection, it is therefore critical to identify the governing factors of groundwater chemistry. Samples of reclaimed water, river and groundwater were collected monthly at Chaobai River from January to September in 2010. Fifteen water parameters were analyzed. Two kinds of reclaimed water were different in type (Na-Ca-Mg-Cl-HCO3 or Na-Ca-Cl-HCO3 ) and concentration of nitrogen. The ionic concentration and type in river were similar to reclaimed water. Some shallow wells near the river bed had the same type (Na-Ca-Mg-Cl-HCO3 ) and high concentration as reclaimed water, but others were consistent with the deep wells (Ca-Mg-HCO3 ). Using cluster analysis, the 9 months were divided into two periods (dry and wet seasons), and all samples were grouped into several spatial clusters, indicating different controlling mechanisms. Principal component analysis and conventional ionic plots showed that calcium, magnesium and bicarbonate were controlled by water-rock interaction in all deep and some shallow wells. This included the dissolution of calcite and carbonate weathering. Sodium, potassium, chloride and sulfate in river and some shallow wells recharged by river were governed by evaporation crystallization and mixing of reclaimed water. But groundwater chemistry was not controlled by precipitation. During the infiltration of reclaimed water, cation exchange took place between (sodium, potassium) and (calcium, magnesium). Nitrification and denitrification both happened in most shallow groundwater, but only denitrification in deep groundwater. | Yilei Yu Xianfang Song Yinghua Zhang Fandong Zheng Ji Liang Dongmei Han Ying Ma Hongmei Bu | 2013 | Journal of Environmental Sciences2013，25，9： | 6 |
| 7 | Effects of fluoxetine on protein expression of potassium ion channels in the brain of chronic mild stress rats显示文摘The purpose of this study is to investigate the expression of major potassium channel subtypes in the brain of chronical mild stress(CMS) rats and reveal the effects of fluoxetine on the expression of these channels. Rats were exposed to a variety of unpredictable stress for three weeks and induced anhedonia, lower sucrose preference, locomotor activity and lower body weight. The protein expressions were determined by Western blot. CMS significantly increased the expression of Kv2.1 channel in frontal cortex but not in hippocampus, and the expression level was normalized after fluoxetine treatment. The expression of TREK-1 channel was also obviously increased in frontal cortex in CMS rats. Fluoxetine treatment might prevent this increase. However, the expression of Kv3.1 and Kv4.2 channels was considerably decreased in hippocampus after CMS, and was not affected by fluoxetine. These results suggest that different subtypes of potassium channels are associated with the pathophysiology of depression and that the therapeutical effects of fluoxetine may relate to Kv2.1 and TREK-1 potassium channels. | Chunlin Chen Ling Wang Xianfang Rong Weiping Wang Xiaoliang Wang | 2015 | Acta Pharmaceutica Sinica B2015，5，1： | 6 |
| 8 | Differential expression of microRNAs in dorsal root ganglia after sciatic nerve injury显示文摘This study investigated the possible involvement of microRNAs in the regulation of genes that participate in peripheral neural regeneration.A microRNA microarray analysis was conducted and 23 microRNAs were identified whose expression was significantly changed in rat dorsal root ganglia after sciatic nerve transection.The expression of one of the downregulated microRNAs,microRNA-214,was validated using quantitative reverse transcriptase-PCR.MicroRNA-214 was predicted to target the 3′-untranslated region of Slit-Robo GTPase-activating protein 3.In situ hybridization verified that microRNA-214 was located in the cytoplasm of dorsal root ganglia primary neurons and was downregulated following sciatic nerve transection.Moreover,a combination of in situ hybridization and immunohistochemistry revealed that microRNA-214 and Slit-Robo GTPase-activating protein 3 were co-localized in dorsal root ganglion primary neurons.Western blot analysis suggested that Slit-Robo GTPase-activating protein 3 was upregulated in dorsal root ganglion neurons after sciatic nerve transection.These data demonstrate that microRNA-214 is located and differentially expressed in dorsal root ganglion primary neurons and may participate in regulating the gene expression of Slit-Robo GTPase-activating protein 3 after sciatic nerve transection. | Anjie Lu Zufa Huang Chaoyue Zhang Xianfang Zhang Jiuhong Zhao Haiying Zhang Quanpeng Zhang Song Wu Xinan Yi | 2014 | Neural Regeneration Research2014，9，10： | 5 |
| 9 | Decentration and tilt of plate-haptic multifocal intraocular lenses in myopic eyes显示文摘Background:To investigate the decentration and tilt of plate-haptic multifocal intraocular lenses(MfIOLs)in myopic eyes.Methods:Myopic(axial length[AXL]>24.5 mm)and non-myopic(21.0 mm | Jiaqi Meng Wenwen He Xianfang Rong Ao Miao Yi Lu Xiangjia Zhu | 2020 | Eye and Vision2020，7，1： | 5 |
| 10 | Hepatitis C Virus Attachment Mediated by Apolipoprotein E Binding to Cell Surface Heparan Sulfate显示文摘 | Jieyun Jiang Wei Cun Xianfang Wu Qing Shi Hengli Tang Guangxiang Luo | 2012 | Journal of Virology2012，，13： | 4 |
| 11 | Amendment on the strain measurement of thin-walled human skull shell as intracranial pressure changes显示文摘The human skull, composed of tabula externa, tabula interna, and a porous diploe sandwiched in between, is deformed with changing intracranial pressure (ICP). Because the human skull's thickness is only 6 mm, it is simplified as a thin-walled shell. The objective of this article is to analyze the strain of the thin-walled shell by the stress-strain calculation of a human skull with changing ICP. Under the same loading conditions, using finite element analysis (FEA), the strains of the human skull were calculated and the results were compared with the measurements of the simulative experiment in vitro. It is demonstrated that the strain of the thin-walled shell is totally measured by pasting the one-way strain foils on the exterior surface of the shell with suitable amendment for data. The amendment scope of the measured strain values of the thin-walled shell is from 13.04% to 22.22%. | Xianfang Yue Li Wang Feng Zhou | 2008 | Journal of University of Science and Technology Beijing2008，15，2： | 3 |
| 12 | Improving Shape from Shading with Interactive Tabu Search显示文摘优化从 shading (SFS ) 的基于的形状对初始化敏感:在初始化的错误是差的全面形状重建的一个重要原因。在这份报纸,我们在场帮助借助于用户相互作用克服这个问题的一个方法。在我们的方法有二个关键元素。第一,我们扩大 SFS 考虑一套初始化,而非使用单个的。第二,我们高效地用一个启发式的搜索方法探索这个初始化空格,禁忌搜索,由重建质量的用户评估指导了。合成、真实的图象上的重建结果在提供更理想的形状重建表明我们的方法的有效性。 | Jing Wu Paul L. Rosin Xianfang Sun Ralph R. Martin | 2016 | Journal of Computer Science & Technology2016，31，3： | 3 |
| 13 | Automated brain tumor segmentation on multi-modal MR image using SegNet显示文摘The potential of improving disease detection and treatment planning comes with accurate and fully automatic algorithms for brain tumor segmentation.Glioma, a type of brain tumor, can appear at different locations with different shapes and sizes. Manual segmentation of brain tumor regions is not only timeconsuming but also prone to human error, and its performance depends on pathologists’ experience. In this paper, we tackle this problem by applying a fully convolutional neural network SegNet to 3 D data sets for four MRI modalities(Flair, T1, T1 ce, and T2)for automated segmentation of brain tumor and subtumor parts, including necrosis, edema, and enhancing tumor. To further improve tumor segmentation, the four separately trained SegNet models are integrated by post-processing to produce four maximum feature maps by fusing the machine-learned feature maps from the fully convolutional layers of each trained model. The maximum feature maps and the pixel intensity values of the original MRI modalities are combined to encode interesting information into a feature representation.Taking the combined feature as input, a decision tree(DT) is used to classify the MRI voxels into different tumor parts and healthy brain tissue. Evaluating the proposed algorithm on the dataset provided by the Brain Tumor Segmentation 2017(BraTS 2017)challenge, we achieved F-measure scores of 0.85, 0.81,and 0.79 for whole tumor, tumor core, and enhancing tumor, respectively.Experimental results demonstrate that using SegNet models with 3 D MRI datasets and integrating the four maximum feature maps with pixel intensity values of the original MRI modalities has potential to perform well on brain tumor segmentation. | Salma Alqazzaz Xianfang Sun Xin Yang Len Nokes | 2019 | Computational Visual Media2019，5，2： | 3 |
| 14 | Protective Effects of Calcium Antagonists on Cadmium-induced Toxicity in Rats显示文摘Protective effects of calcium antagonists, chlorpromazine (CPZ) and nimodepine (NI-MO), on cadmium-induced toxicity were investigated. After giving CdCl2 (0. 44mg Cd/kg,ip), CPZ (5mg/kg, ip) or NIMO (8mg/kg, po) were administered every day to Sprague-Dawley (S. D. ) rats for a week. Then, urinary N- acetyl-β-D- glucosaminidase (NAG ), uri -nary cadmium and bloocl cadmium were measured. The accumulation of cadmium in the kid-ney cortex, content of renal calmodulin, hemoglobin and the ultrastructural damage of proxi-mal convoluted tubules of rats were examined three weeks after the last administration. Re-sults indicated that the calcium antagonists partly protected against toxic effects induced bycadmium in different manners. These data provide further evidence for the new hypothesisthat the cross effect of cadmium and calcium in calmodulin regulated systems may be responsi-ble for the mechanism of cadmium intoxication. ’The results suggested that the calcium antag-onists could be a new and promising approach in the therapy of heavy metaLinduced | YANG XIANFANG YANG YONG-NIAN(Institute of Applied Toxicology, Nanjing the Medical University,Nanjing 210029, China)Abbreviation are Ca, calcium CaM, calmodulin Cd, cadmium CPZ, chlorpromazine Hb, hemogobin NIMO, nimodepine NAG, N-acetyl-β-D- gluco | 1997 | Biomedical and Environmental Sciences1997，10，4： | 3 |
| 15 | Electroelastic field induced by thin interface electrodes between two bonded dissimilar piezoelectric ceramics显示文摘The electroelastic analysis of multiple collinear electrodes embedded at the interface of two bonded dissimilar piezoelectric ceramics is made. Within the framework of linear piezoelectricity, the Fourier transform technique is applied to reducing the problem to a singular integral equation with Cauchy kernel. Two particular cases are especially emphasized. For a single interface electrode, the electroelastic field is obtained in the entire plane of a two-phase piezoelectric composite in terms of elementary functions. For two collinear interface electrodes of equal length, a closed-form solution is determined along the interface. Obtained results reveal that near the electrode edges, the induced electroelastic field exhibits a square-root singularity, and the oscillatory singularity does not occur for arbitrary two piezoelectric ceramics poled in the same or opposite directions normal to the interface. Across the electrode, the normal component of stress is continuous, while that of strain exhibits a jump, implying strain incompatibility due to the mismatch of the material properties of two dissimilar poled ceramics. | LI Xianfang | 2006 | Science China(Physics,Mechanics & Astronomy)2006，49，5： | 3 |
| 16 | Screening Winter Wheat Germplasm for Fusarium Head Blight Resistance显示文摘58 winter wheat breeding lines and 4 widely popularized varieties in Huaihe River wheat production regions of Anhui were used to screen resistant germplasms to Fusarium head blight. Incidence, disease index, percentage of infected kernels and DON content in the kernels were measured for each variety or line following artificial inoculation of Fusarium spp. pathogens. Reactions of wheat to Fusarium infection varied among genotypes and different types of resistance. The incidence of infection for each variety or line highly correlated to the severity of colonization after infection. DON content was more correlated to the percentage of kernels infected than to the overall incidence or severity. The selected control varieties were all susceptible to FHB, while seven breeding lines demonstrated good resistant performance. New FHB resistant winter wheat varieties appealing to the actual needs are expected from them. | Ze LIU Li ZHAO Xianfang HE Jianlai WANG | 2015 | Agricultural Science & Technology2015，16，9： | 2 |
| 17 | Impact of Fungicide Treatments on the Constitution of Unsound Wheat Kernels显示文摘Nine fungicides were applied,either through seed-dressing or post-anthesis foliar-spray,to eight winter wheat varieties to understand their influences on the constitution of unsound kernels during the 2017-2018 growth season in Funan Experimental Station,Anhui,P.R.China.Three unsound kernel items,i.e.Fusarium-damaged kernels( FDKs),black-germ kernels( BGKs) and pre-harvest sprouted kernels( PHSKs),were measured from the harvested grains.A high percentage of unsound kernels was noticed as 6.00% for FDKs,8.43% for BGKs,and 38.19% for PHSKs due to excessive precipitation during the filling and maturation stages within the season.Fungicide treatments showed positive impacts on the formation of FDKs and BGKs.No significant differences were noticed on the percentage of PHSKs among treatments.The best control efficiency on FDKs,24.63%,was observed in the treatment of‘tebuconazole + prochloraz-manganese chloride complex'.The highest control efficiency on BGKs,31.54%,was achieved by the treatment of‘phenazino-1-carboxylic acid'.Significant differences were noticed among varieties with respect to the constitution of unsound kernels.Under the specific ecological conditions,70%-75% of the final grain quality of wheat was determined by the genotype itself.It was concluded that the genetic resistance or tolerance to relevant fungal pathogens and pre-harvest sprouting was the key factor determining the constitution of unsound wheat kernels,whilst chemical control might function with limited effects when crop was grown under high-pressure or stress conditions. | Ze LIU Yiliang QIAN Li ZHAO Xianfang HE Jianlai WANG | 2018 | Agricultural Biotechnology2018，7，6： | 2 |
| 18 | Identification and Characterization of Peptides Mimicking the Epitopes of Metalloprotease of Schistosoma Japonicum显示文摘In an attempt to isolate and characterize peptides mimicking epitopes of metalloprotease and explore their immunological protection against Schistosoma japonicum (S. japonicum), polyclonal anti-metalloprotease sera was prepared to screen a 12-mer random peptide library to isolate phages binding specially to antisera IgG. Then,phage ELISA, animal immunization, DNA sequencing, Western blotting and enzymatic activity neutralizing analysis were used to characterize the selected phage clones. All of ten randomly picked clones were shown to be positive. Five peptides of different amino acid sequences deduced from DNA sequences were obtained and two of them (peptides 2 and 3) could induce significant reduction (31.0% and 31.8%, respectively) in worm burden and high reduction (52.6% and 54.9%, respectively) in liver eggs per gram (LEPG), while, unexpectedly, others (peptides 1, 4 and 5) could not elicit enough protection against infection of S. japonicum. Peptides 2 and 3 could be recognized by S. japonicum infected mouse sera (IMS) and could elicit neutralizing Abs. The results show that peptides 2 and 3 are antigenic and immunogenic. They are true mimics of epitopes of metalloprotease and useful as novel vaccine candidates against S. japonicum. | Lianfei Tang Yuxiao Chen Linqian Wang Shunke Zhang Xianfang Zeng Xinyuan Yi | 2005 | Cellular & Molecular Immunology2005，2，3： | 2 |
| 19 | Effect of Land Use on Soil Properties in Debris Flow Bottomland:A Case Study at Xiaojiang Basin, Yunnan显示文摘In order to understand the effect of different land use on soil physics and nutrients properties of the debris flow bottomland, a case study at Daqing gully (in Xiaojiang Basin, Yunnan) was conducted in 2004. Soil samples were taken at depth of 0-10,10-20,20-40,40-60,60-80 cm under three land use patterns crop bottomland(CL), forest bottomland(FL), and barren bottomland(BL). The results showed that the developing bottomland to CL promoted soil toaccumulate total phosphorus (TP) and available phosphorus (AP), pH value transferred from neutral to alkalescency, and organic matter decreased significantly. Furthermore, the contents of total nitrogen (TN) and available nitrogen (AN) in CL were lower than that of FL and BL because the growth of crops consumed more nutrients in soil. The results also showed that the contents of TP, AP and available potassium (AK) in soil were positively correlated with soil particle. | ZHANG Qiuying LI Fadong LIU Mengy SONG Xianfang OU Guoqiang | 2006 | Wuhan University Journal of Natural Sciences2006，11，4： | 2 |
| 20 | Geochemical and isotopic evidence for palaeo-seawater intrusion into the south coast aquifer of Laizhou Bay, China显示文摘 | HAN Dongmei KOHFAHL C SONG Xianfang | 2011 | Applied Geochemistry2011，26，： | 1 |
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