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| 1 | Double-stranded DNA in exosomes: a novel biomarker in cancer detection显示文摘 | Basant Kumar Thakur Haiying Zhang Annette Becker Irina Matei Yujie Huang Bruno Costa-Silva Yan Zheng Ayuko Hoshino Helene Brazier Jenny Xiang Caitlin Williams Ruth Rodriguez-Barrueco Jose M Silva Weijia Zhang Stephen Hearn Olivier Elemento Navid Paknejad Katia Manova-Todorova Karl Welte Jacqueline Bromberg Hector Peinado David Lyden | 2014 | Cell Research2014，24，6： | 98 |
| 2 | Up-regulation of Bcl-2 is required for the progression of prostate cancer cells from an androgen-dependent to an androgen-independent growth stage显示文摘Bcl-2 是 anti-apoptotic oncoprotein,它的蛋白质层次相反地在许多癌症与预后被相关。然而,在前列腺癌症的前进的 Bcl-2 的角色不是清楚的。这里,我们报导 Bcl-2 从一个雄激素依赖者为 LNCaP 前列腺癌症细胞的前进被要求到一个雄激素无关的生长阶段。Bcl-2 的信使 rna 和蛋白质层次显著地在雄激素无关的前列腺癌症被增加在雄激素无关的前列腺癌症房间的 Bcl-2 的调停 cells.shRNA 的基因 silencing 导致 promotesUV 的 apoptosis 并且压制前列腺肿瘤的生长体内。在在形成的雄激素剥夺条件结果下面的 Growingandrogen 依赖的房间 ofandrogen 独立的殖民地;并且到 androgen-independentgrowth 的从雄激素依赖者的转变被 Bcl-2 对手 Bax 或 Bcl-2 shRNA 的宫外的表示堵住。因此,我们的结果证明 Bcl-2 为 androgen-independentprostate 癌症细胞的幸存是批评的不仅,但是也为前列腺癌症细胞的前进被要求从对一个雄激素无关的生长阶段 anandrogen 依赖。 | Yuting Lin Junichi Fukuchi Richard A Hiipakka John M Kokontis Jialing Xiang | 2007 | Cell Research2007，17，6： | 5 |
| 3 | Involvement and therapeutic implications of airway epithelial barrier dysfunction in type 2 inflammation of asthma显示文摘Type 2 inflammation is a complex immune response and primary mechanism for several common allergic diseases including allergic rhinitis,allergic asthma,atopic dermatitis,and chronic rhinosinusitis with nasal polyps.It is the predominant type of immune response against helminths to prevent their tissue infiltration and induce their expulsion.Recent studies suggest that epithelial barrier dysfunction contributes to the development of type 2 inflammation in asthma,which may partly explain the increasing prevalence of asthma in China and around the globe.The epithelial barrier hypothesis has recently been proposed and has received great interest from the scientific community.The development of leaky epithelial barriers leads to microbial dysbiosis and the translocation of bacteria to inter-and sub-epithelial areas and the development of epithelial tissue inflammation.Accordingly,preventing the impairment and promoting the restoration of a deteriorated airway epithelial barrier represents a promising strategy for the treatment of asthma.This review introduces the interaction between type 2 inflammation and the airway epithelial barrier in asthma,the structure and molecular composition of the airway epithelial barrier,and the assessment of epithelial barrier integrity.The role of airway epithelial barrier disruption in the pathogenesis of asthma will be discussed.In addition,the possible mechanisms underlying the airway epithelial barrier dysfunction induced by allergens and environmental pollutants,and current treatments to restore the airway epithelial barrier are reviewed. | Xiang Dong Mei Ding Jinjin Zhang Ismail Ogülür Yagiz Pat Mübeccel Akdis Yadong Gao Cezmi A.Akdis | 2022 | Chinese Medical Journal2022，，5： | 4 |
| 4 | Successful operation of a cooperative SLR station of China and Argentina in San Juan显示文摘We introduced the observations and researches using a Satellite Laser Ranging (SLR) system with high precision, which was designed and made in China and installed in the Observatory of San Juan Uni- versity, Argentina, the capability of the system and the achievement of the cooperative procedure be- tween China and Argentina. The SLR station in San Juan, set up by China and Argentina, is quite sig- nificant for improving the distribution of SLR stations and enhancing the orbital coverage of the whole earth. Since the SLR system started to work in the Observatory of San Juan University in the beginning of 2006, the operation is rather good, and rich data with high precision have been obtained. Further plan of the cooperation for the near future is also presented. | HAN YanBen LIU WeiDong E ACTIS R PODESTA WANG TanQiang GUO TangYong QU Feng A M PACHECO A A GONZALEZ E ALONSO XIANG QingGe HUANG DongPing YIN ZhiQiang | 2008 | Chinese Science Bulletin2008，53，16： | 2 |
| 5 | Factors Affected HIV Testing and HIV Infection among Internet-based Self-testing MSM Who Never Tested for HIV in Beijing,China显示文摘Around half of the men who have sex with men(MSM)have never been tested for human immunodeficiency virus(HIV),even though the health authorities promoted a massive scale-up of HIV testing and counseling in health facilities[1].HIV self-testing has been recommended by the World Health Organization as a user-friendly,convenient,rapid,and accurate approach to access HIV testing[2].An internet-based provision of self-testing services may be critical to the rollout of HIV self-testing,but more research is needed. | JIN Xia XIAO Dong XU Jun Jie SMITH M Kumi XIU Xiang Fei DING Zheng Wei CAO Ning Xiao BAO Yu Gang | 2020 | Biomedical and Environmental Sciences2020，33，10： | 2 |
| 6 | MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca^sup 2+^ overload and cell death显示文摘 | Aurora Arin B Mahmoud Ahmed I Luo Xiang Johnson Brett A van Rooij Eva Matsuzaki Satoshi Humphries Kenneth M Hill Joseph A Bassel-Duby Rhonda Sadek Hesham A Olson Eric N | 2012 | EN2012，，4： | 2 |
| 7 | Alterations in the PITSLRE protein kinase gene complex on chromosome P36 in childhood neuroblastoma显示文摘 | Lahit JM Valentine M Xiang J | 1994 | Nat Genet1994，7，： | 2 |
| 8 | Characterization of efficient aerobic denitrifiers isolated from two different sequenceing batch reactors by 16S rRNA analysis 显示文摘 | Wang P Li X Xiang M | 2007 | Journal of Bioscience and Bioengineering2007，103，6： | 1 |
| 9 | A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication显示文摘 | Xiang R Mizutani N Luo Y Chiodoni C Zhou H Mizutani M | 2005 | Cancer Res2005，65，： | 1 |
| 10 | Croeetin inhibits leukocyte adherence to vascular endothelial cells induced by AGEs 显示文摘 | Xiang M Qian ZY Zhou CH | 2006 | J Ethnopharmaeol2006，107，1： | 1 |
| 11 | Combinded use of computed tomography coronary calcium socres and C reactive protein levers in predicting cardiovascular events in notidiabetic individuals显示文摘 | Park R Detronok R Xiang M | 2002 | Circulation2002，106，16： | 1 |
| 12 | Hydrogen-induced degradation in CaCu3Ti4O12 ceramics 显示文摘 | Chen W P Xiang W Guo M S | 2006 | J Alloys Compounds2006，422，： | 1 |
| 13 | SKP2/P27 expression Profile is correlated with epstein-Barr virus status in extranodal nasal-type natural Killer cell lymphoma显示文摘 | Xiang L M Zu L S Dan H | 2008 | Transl Res2008，151，6： | 1 |
| 14 | Energy efficient clustering al- gorithm for maximizing lifetime of wireless sensor networks 显示文摘 | Xiang M Shi W R Jiang C J | 2010 | In- ternational Journal of Electronicsand Communications2010，64，5： | 1 |
| 15 | Cumulative second-harmonic analysis of ultrasonic lamb waves for ageing be- havior study of modified-HP austenite steel显示文摘 | XIANG Y X DENG M X XUAN F Z | 2011 | Ultrasonics2011，51，： | 1 |
| 16 | Crocetin inhibits leu?kocyte adherence to vascular endothelial cells induced by AGEs显示文摘 | XIANG M QIAN Z Y ZHOU C H | 2006 | J Ethnopharmacol2006，107，1： | 1 |
| 17 | Exploring the neutral invertase-oxidative stress defence connection in Ara-bidopsis thaliana显示文摘 | XIANG L LE ROY K BOLOURI-MOGHADDAM M K etal | 2011 | Journal of Experimental Botany2011，6211，： | 1 |
| 18 | Solid-state digital micro-mirror array spectrometer for Hadamard transform measurements of glucose and lactate in aqueous solutions 显示文摘 | Xiang D Arnold M A | 2011 | Applied Spectroscopy2011，65，10： | 1 |
| 19 | Evaluation of direct Infusion-multiple reaction monitoring mass spectrometry for quantification of heat shock proteins显示文摘 | Xiang Y Koomen J M | | 0，，： | 1 |
| 20 | Regression reformulations of LLE and LTSA with locally linear transformation显示文摘 | Xiang S M Nie F P Pan C H | | 0，，： | 1 |
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