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| 1 | FEM Analysis of Spring-backs in Age Forming of Aluminum Alloy Plates显示文摘The age forming technology, characterized by huge spring-backs, has been developed to manufacture large integral wing-skin panel parts, which necessitates devising a method of predicting spring-backs. A 7B04-T7451 aluminum alloy creep test in tension is accomplished at 155 °C, and the creep curves are obtained. The material constants of the mechanism-based creep constitutive equations are determined through experiments. The age forming process and the spring-backs of 7B04 aluminum alloy plates are analyzed using the commercial finite element software ABAQUS. The effects of plate thickness and forming time on spring-backs are researched. The spring-backs decrease with the increase of plate thickness and forming time. The test results verify the reliability of the finite element method (FEM) analysis. | Huang Lin Wan Min Chi Cailou Ji Xiusheng | 2007 | Chinese Journal of Aeronautics2007，20，6： | 23 |
| 2 | CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys显示文摘Dear Editor,PINK1 mutations cause autosomal recessive and early-onset Parkinson’s disease(PD)with selective neurodegeneration.Unfortunately,current PINK1 knockout(KO)mouse1,2 and pig models3,4 are unable to recapitulate the selective and overt neurodegeneration seen in PD patients.Furthermore,endogenous Pink1 in the mouse brain is expressed at very low levels and can only be detected via immunoprecipitation,5 meaning that PINK1’s function in the mammalian brain needs to be assessed using larger animals that are closer to humans.We previously used CRISPR/Cas9 to target the monkey gene in one-cell stage embryos.6 Using the same approach,we designed two gRNAs to target exon 2(T1)and exon 4(T2),which encode a kinase domain in the PINK1 gene of rhesus monkeys(Fig.1a).CRISPR/Cas9 and PINK1 gRNAs were injected into one-cell stage rhesus monkey embryos.A T7E1 assay and sequencing of PCR products from the injected embryos showed high efficiency(61.5%)in targeting PINK1(Fig.1b and Supplementary information,Fig.S1).Transfer of 87 embryos to 28 surrogate rhesus monkeys resulted in 11 pregnancies(39.2%)(Fig.1b).Eleven fetuses developed to term and were born naturally.Of these live monkeys,eight carried PINK1 mutations(M),and three were wild type(WT).However,three mutant monkeys(M1,M3 and M4)were newborn triplets that struggled to survive and died 3-4 days after birth.One WT newborn monkey also died after a difficult labor.Another mutant monkey(M2)died 7 days after birth without noticeable warning signs or symptoms.The other three mutant monkeys(M6,M7 and M8)have lived for three years;M5,however,reduced its food intake and showed weakness at the age of 1.5 years,and died 30 days after anesthesia for MRI examination. | Weili Yang Yunbo Liu Zhuchi Tu Chong Xiao Sen Yan Xishan Ma Xiangyu Guo Xiusheng Chen Peng Yin Zhengyi Yang Su Yang Tianzi Jiang Shihua Li Chuan Qin Xiao-Jiang Li | 2019 | Cell Research2019，29，4： | 12 |
| 3 | Sensor scheduling for ground maneuvering target tracking in presence of detection blind zone显示文摘Continuous and stable tracking of the ground maneuvering target is a challenging problem due to the complex terrain and high clutter. A collaborative tracking method of the multisensor network is presented for the ground maneuvering target in the presence of the detection blind zone(DBZ). First, the sensor scheduling process is modeled within the partially observable Markov decision process(POMDP) framework. To evaluate the target tracking accuracy of the sensor, the Fisher information is applied to constructing the reward function. The key of the proposed scheduling method is forecasting and early decisionmaking. Thus, an approximate method based on unscented sampling is presented to estimate the target state and the multi-step scheduling reward over the prediction time horizon. Moreover, the problem is converted into a nonlinear optimization problem, and a fast search algorithm is given to solve the sensor scheduling scheme quickly. Simulation results demonstrate the proposed nonmyopic scheduling method(Non-MSM) has a better target tracking accuracy compared with traditional methods. | XU Gongguo SHAN Ganlin DUAN Xiusheng | 2020 | Journal of Systems Engineering and Electronics2020，31，4： | 9 |
| 4 | 环式入渗仪测量土壤初始入渗率效果试验显示文摘提出一种环式入渗试验装置,可以在入渗进行一段时间后,通过观测初始入渗水在土壤剖面的分布,估量初始入渗的过程。该入渗环为可拆分的两个半环,以便通过观察入渗水分在土壤剖面的分布估计初始入渗特性。论述了环的构成和测量过程与方法。同时用有机玻璃圆管装填土样,对比观察模拟真实一维入渗过程。用采自北京的粉壤土和该试验装置进行土壤入渗试验。试验分为3种入土打击能量:1、2、4 kg铁锤,自1 m高处自由落体打击入渗环入土。土壤干体积容积密度分别为:1.2、1.3、1.4 g/cm3。每次试验均向环内注入2 L水,每组试验进行2次重复。入渗环内土壤湿润土体表明,实际发生的土壤入渗为由环壁向环内土壤的径向入渗和由地表向下垂直入渗构成,环壁与土壤剖面间产生的优先流极大地影响了初始土壤入渗率的测量精度。在初始入渗阶段,由环壁向土体的水平径向入渗宽度和由地表向土体的垂直入渗深度近似相等,垂直入渗深度是水平径向入渗宽度的1.001倍。环式入渗仪测得的土壤初始入渗率为模拟真实一维入渗率的3.3倍。研究结果可为环式入渗仪测量结果的评估提供参考。 | 张婧 雷廷武 张光辉 蔡崇法 黄炎和 Yang Xiusheng | 2014 | 农业机械学报2014，45，10： | 9 |
| 5 | On the Structure of Cyclic Codes over F_q+uF_q+vF_q+uvF_q显示文摘In this paper,cyclic codes over the ring R=F4+uF4+vF4+uvF4 are discussed where the ring R is not a finite chain ring.By studying the polynomial ring Rn=(F4+uF4+vF4+uvF4) and using the corresponding relationship between the cyclic codes in R and the ideals in,cyclic codes over the ring R are characterized.Finally,a Gray-map is obtained and the image of cyclic codes in R is characterized. | XU Xiaofang LIU Xiusheng | 2011 | Wuhan University Journal of Natural Sciences2011，16，5： | 5 |
| 6 | Two Confirmed Patients of Anthrax—Binzhou City,Shandong Province,China,August 2021显示文摘As of August 15,2021,2 confirmed cases of anthrax were reported to Shandong CDC,one of which was a 14-year-old student(Patient A)and the other was a 35-year-old man(Patient B)engaging in the slaughter of cattle.Patient A died on August 6,and Patient B has been transferred to an infectious disease hospital for isolation and treatment.The Shandong CDC formed a joint investigation team to determine the source of infection and prevent any further spread. | Xiaolin Yu Lifang Zhang Ming Fang Hao Liang Qi Zhang Xiusheng Yin Zengqiang Kou Wenwu Yin Zhong Li Enmin Zhang Shujun Ding | 2021 | China CDC weekly2021，3，38： | 4 |
| 7 | Potential production and spatial distribution of hybrid poplar as a biofuel crop in Connecticut,USA显示文摘The objective of this study was to assess the biomass production potential from hybrid poplars using marginal lands in the state of Connecticut,USA.A land-use suitability model was developed to identify and classify marginal lands in the state that could be used for growing hybrid poplars as a biofuel woody energy crop.The model was built on a geographic information system(GIS)platform,consisting of an exclusion area section,an ecological suitability section,and an economic/land-use suitability section.The model then was used to estimate the total biomass of the land-cover forests,annual biomass from forest and agricultural residues,and in particular the production potential of biomass from hybrid poplars over marginal lands in the state at county level.The results indicated that about 50%of the land in this state is unavailable for hybrid poplar cultivation and that less than 5%is highly suitable.The amount of usable area is highly variable on the county level.Without large-scale land use change,it appears that biofuel production in this state can only be a supplemental resource to the current energy supply. | Zhao Xue Liqin Qu Xiusheng Yang | 2014 | International Journal of Agricultural and Biological Engineering2014，7，2： | 4 |
| 8 | PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis显示文摘In vitro studies have established the prevalent theory that the mitochondrial kinase PINK1 protects neurodegeneration by removing damaged mitochondria in Parkinson's disease(PD).However,difficulty in detecting endogenous PINK1 protein in rodent brains and cell lines has prevented the rigorous investigation of the in vivo role of PINK1.Here we report that PINK1 kinase form is selectively expressed in the human and monkey brains.CRISPR/Cas9-mediated deficiency of PINK1 causes similar neurodegeneration in the brains of fetal and adult monkeys as well as cultured monkey neurons without affecting mitochondrial protein expression and morphology.Importantly,PINK1 mutations in the primate brain and human cells reduce protein phosphorylation that is important for neuronal function and survival.Our findings suggest that PINK1 kinase activity rather than its mitochondrial function is essential for the neuronal survival in the primate brains and that its kinase dysfunction could be involved in the pathogenesis of PD. | Weili Yang Xiangyu Guo Zhuchi Tu Xiusheng Chen Rui Han Yanting Liu Sen Yan Qi Wang Zhifu Wang Xianxian Zhao Yunpeng Zhang Xin Xiong Huiming Yang Peng Yin Huida Wan Xingxing Chen Jifeng Guo Xiao-Xin Yan Lujian Liao Shihua Li Xiao-Jiang Li | 2022 | Protein & Cell2022，13，1： | 3 |
| 9 | China's adjustment of climate change policies:what lessons can be learned from the US?显示文摘From the US New Energy Plan, personnel appointment, and diplomatic activities, etc., we can see that US is now on the way to returning to the negotiation table and undertaking the leadership in addressing climate change. What US has done puts tremendous challenges on China, which emits large amount of greenhouse gas into the atmosphere. However, different from US, China is undergoing rapid development, and huge energy consumption is unavoidable. China has to make a balance between developing economy and addressing climate change. This paper focuses on the US climate change policies and its greenhouse gas emissions, and its influences on China climate change policy. China greenhouse gas emissions and relative policies are also analyzed to see what situation China is in, and what challenges that China is facing. Consequently, combing China's local situation, we propose several solutions for China to address climate change, i.e. moving towards a low carbon economy, struggling for emitting more, enhancing China-US cooperation, and implementing different climate change policies based on local situation. Meanwhile, the achievements that China has made are also introduced. | Liu Mingming Zhao Xiusheng | 2009 | Ecological Economy2009，5，3： | 2 |
| 10 | Development and validation of atmospheric gene flow model for assessing environmental risks from transgenic corn crops显示文摘Pollen-mediated gene flow from genetically modified plants to non-target plants is a concern of crop growers,seed companies,the general public,and the scientific communities.Although there have been descriptive and mechanistic models to describe pollen dispersion,there has rarely been a comprehensive mechanistic model to dynamically simulate pollen release,dispersion,and deposition and to finally relate them to the gene flow(outcrossing).This research developed and validated such a comprehensive mechanistic model for corn crop gene flow risk management.Dynamic pollen dispersion and deposition were predicted by a 3-D random walk model according to inputs of weather data and plant and domain characteristics.Actual gene flow(outcrossing ratio)was obtained according to predicted grand total deposition flux at silk height during the whole pollination season.The model was validated by experimental data and was appropriate to predict gene flow with acceptable accuracy under different atmospheric and environmental conditions;on average,the ratios of measured and simulated values ranged from 0.82 to 1.21,while R2 ranged from 0.56 to 0.68.The model can be easily adapted for other genetically modified crops. | Junming Wang Xiusheng Yang | 2010 | International Journal of Agricultural and Biological Engineering2010，3，2： | 2 |
| 11 | 体积置换法测量土石混合物组分含量显示文摘土石混合物组分含量测量在农业生产、建筑施工及水利工程等方面都有重要的意义。该文根据体积置换原理测量土石混合物比例、土壤含水率、容重、孔隙度/孔隙比等一系列土壤物理参数。给出了测量原理、设备、试验方法与过程。采用陕西杨凌的黏黄土、吉林黑土以及粒径为5~10 mm的石砾,预制不同体积含水率(10%、15%、20%)、石砾体积比例(10%、15%、20%)和土壤颗粒体积比例(40%、45%、50%)的土样。首先采用体积置换法测得土样中石砾、土壤颗粒和土壤水的总体积,随后取出土样中的石砾,用体积置换法测得石砾体积,进而得到土壤颗粒和土壤水的体积,并据此得到土壤含水率、土壤容重、土中气体含量、土壤孔隙度和孔隙比。用烘干法测量得到土壤容重和含水率,将2种方法测得的结果对比分析表明,使用体积置换法测得的土壤含水率比烘干法测量的结果大,相对误差在5%左右,测量的土壤容重偏小约1%,土壤气体含量的测量相对误差约为2%。测量土壤孔隙度的相对误差约为1%,土壤孔隙比的测量误差为1%~1.5%。表明体积置换法可以较为准确地测量土石混合物中各组分的相对含量,具有操作便捷、测量精度高、有普遍适用性等优点,可以为相关研究和测量提供参考。 | 马玉莹 雷廷武 Xiusheng Yang | 2015 | 农业工程学报2015，31，9： | 2 |
| 12 | Experimental research of high performance concrete with multi-elements mineral admixtures显示文摘 | Li Keliang Tang Xiusheng Huang Guohong | 2009 | Key Engineering Materials2009，，： | 1 |
| 13 | A tandem mass spectrometric study of the N-oxides, quinoline N-oxide, carbadox, and olaquindox, carried out at high mass accuracy using electrospray ionization显示文摘 | MIAO Xiusheng MARCH R E METCALFE C D | 2003 | International Journal of Mass Spectrometry2003，230，： | 1 |
| 14 | Expression,mutationand deletion of p16 gene in gastric carcinoma显示文摘 | HE Xiusheng SU Qi CHEN Zhuchu | 2001 | World Journal of Gastroenterology2001，7，： | 1 |
| 15 | A dynamic modeling ap- proach to simulating socioeconomic effects on landscape changes 显示文摘 | Wang Yeqiao Zhang Xiusheng | 2001 | Ecological Modelling2001，140，12： | 1 |
| 16 | Effect of nanoparticle surfacetreatment on nonisothermal crystallization behavior of polypropylene / calcium carbonate nanocomposites显示文摘 | Yu Demei Guo Xiusheng | 2008 | Polymer Plastics Technology and Engineering2008，47，4： | 1 |
| 17 | Sparse coding based visual tracking: Review and experimental comparison显示文摘 | Shengping Zhang Hongxun Yao Xin Sun Xiusheng Lu | 2012 | Pattern Recognition2012，，： | 1 |
| 18 | Oxygen permeation and electrical transport of Gd1-x PrxBaCo2O5+δ debse membranes显示文摘 | Yang Chunli Wu Xiusheng Fang Shumin | 2009 | Mater Lett2009，63，12： | 1 |
| 19 | Effects of geographical location and land use on atmospheric deposition of nitrogen in the State of Connecticut显示文摘 | Yuzhou Luo Xiusheng Yang Robert J. Carley Christopher Perkins | 2003 | Environmental Pollution2003，，3： | 1 |
| 20 | Formulation of bidirectional atmosphere-surface exchanges of elemental mercury显示文摘 | Xu Xiaohong Yang Xiusheng Miller D R Helble J J Cartey R J | 1999 | Atmospheric Environment1999，33，： | 1 |
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