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| 1 | The regulation of the Treg/Th 17 balance by mesenchyma stem cells in human systemic lupus erythematosus显示文摘 | Dandan Wang Saisai Huang Xinran Yuan Jun Liang Renju Xu Genhong Yao Xuebing Feng Lingyun Sun | 2017 | Cellular & Molecular Immunology2017，14，5： | 44 |
| 2 | Lipase-Catalyzed Synthesis of Sn-2 Palmitate: A Review显示文摘Human milk fat(HMF)is an important source of nutrients and energy for infants.Triacylglycerols(TAGs)account for about 98%of HMF and have a unique molecular structure.HMF is highly enriched in palmitic acid(PA)at the sn-2 position of the glycerol backbone(more than 70%)and in unsaturated fatty acids at the sn-1,3 position.The specific TAG structure in HMF plays a valuable function in infant growth.Sn-2 palmitate(mainly 1,3-dioleoyl-2-palmitoyl-glycerol)is one of the structured TAGs that is commonly supplemented into infant formula in order to enable it to present a similar structure to HMF.In this review,the development of the lipase-catalyzed synthesis of sn-2 palmitate over the last 25 years are summarized,with a focus on reaction schemes in a laboratory setting.Particular attention is also paid to the commercialized sn-1,3 regioselective lipases that are used in structured TAGs synthesis,to general methods of TAG analysis,and to successfully developed sn-2 palmitate products on the market.Prospects for the lipase-catalyzed synthesis of sn-2 palmitate are discussed. | Wei Wei Cong Sun Xiaosan Wang Qingzhe Jin Xuebing Xu Casimir CAkoh Xingguo Wang | 2020 | Engineering2020，6，4： | 5 |
| 3 | Fault detection of flywheel system based on clustering and principal component analysis显示文摘Considering the nonlinear, multifunctional properties of double-flywheel with closedloop control, a two-step method including clustering and principal component analysis is proposed to detect the two faults in the multifunctional flywheels. At the first step of the proposed algorithm,clustering is taken as feature recognition to check the instructions of ‘‘integrated power and attitude control' system, such as attitude control, energy storage or energy discharge. These commands will ask the flywheel system to work in different operation modes. Therefore, the relationship of parameters in different operations can define the cluster structure of training data. Ordering points to identify the clustering structure(OPTICS) can automatically identify these clusters by the reachability-plot. K-means algorithm can divide the training data into the corresponding operations according to the reachability-plot. Finally, the last step of proposed model is used to define the relationship of parameters in each operation through the principal component analysis(PCA) method.Compared with the PCA model, the proposed approach is capable of identifying the new clusters and learning the new behavior of incoming data. The simulation results show that it can effectively detect the faults in the multifunctional flywheels system. | Wang Rixin Gong Xuebing Xu Minqiang Li Yuqing | 2015 | Chinese Journal of Aeronautics2015，28，6： | 5 |
| 4 | Histone acetylation of the htr3a gene in the prefrontal cortex of Wistar rats regulates ethanol-seeking behavior显示文摘Previous reports showed that decreased histone deacetylase activity significantly potentiated the rewarding effects of psychostimulants,and that encoding of the 5-HT3 receptor by the htr3a gene was related to ethanol-seeking behavior.However,the effects of a histone deacetylase inhibitor on ethanol-seeking behavior and epigenetic regulation of htr3a mRNA expression after chronic ethanol exposure are not fully understood.Using quantitative reverse transcription-polymerase chain reaction and chromatin immunoprecipitation analysis,we investigated the effects of chronic ethanol exposure and its interaction with a histone deacetylase inhibitor on histone-acetylation-mediated changes in htr3a mRNA expression in the htr3a promoter region.The conditioned place preference procedure was used to evaluate ethanol-seeking behavior.Chronic exposure to ethanol effectively elicited place conditioning.In the prefrontal cortex,the acetylation of H3K9 and htr3a mRNA expression in the htr3a promoter region were significantly higher in the ethanol group than in the saline group.The histone deacetylase inhibitor sodium butyrate potentiated the effects of ethanol on htr3a mRNA expression and enhanced ethanol-induced conditioned place preferences.These results suggest that ethanol upregulates htr3a levels through mechanisms involving H3K9 acetylation,and that histone acetylation may be a therapeutic target for treating ethanol abuse. | Yahui Xu Xuebing Liu Xiaojie Zhang Guanbai Zhang Ruiling Zhang Tieqiao Liu Wei Hao | 2012 | Neural Regeneration Research2012，7，13： | 3 |
| 5 | Lipase-catalyzed modification of lard to produce human milk fat substitutes显示文摘 | YANG Tiankui XU Xuebing HE Chuan | | 0，，： | 1 |
| 6 | Enzymatic production of structured lipids: Process reactions and acyl migration显示文摘 | Xuebing Xu | 2000 | Functional Food /Processing2000，，11： | 1 |
| 7 | Production and oxidative stability of a human milk fat substitute produced from lard by enzyme technology in a pilot packed-bed reactor显示文摘 | NIELSEN N S YANG Tiankui XU Xuebing | | 0，，： | 1 |
| 8 | Enzymatic interesterification of palm stearin and coconut oil by a dual lipase system显示文摘 | IBRAHIM N A GUO Zheng XU Xuebing | 2008 | J Am Oil Chem Soc2008，85，1： | 1 |
| 9 | 显示文摘 | Xu Xuebing | 2003 | European Journal of Lipid Science and Tech-nology2003，105，24： | 1 |
| 10 | Human milk fat substitute from butterfat: production by enzymatic interesterification and evaluation of oxidative stability显示文摘 | Serensen AD Xuebing Xu Long Zhang | 2010 | Journal of the American Oil Chemists'' Society2010，87，： | 1 |
| 11 | Enzymatic production of alkyl esters through alcoholysis: A critical evaluation of lipases and alcohols显示文摘 | Li Deng Xuebing Xu Gudmundur G. Haraldsson Tianwei Tan Fang Wang | 2005 | Journal of the American Oil Chemists’ Society2005，，5： | 1 |
| 12 | Monitoring lipase-catalyzed butterfat interesterification with rapeseed oil by Fourier transform near-infrared spectroscopy显示文摘 | Hong Zhang Huiling Mu Xuebing Xu | 2006 | Analytical and Bioanalytical Chemistry2006，，6： | 1 |
| 13 | Enzymatic Interesterifieation of Palm Stearin and Coconut Oil by a Dual Lipase System 显示文摘 | Nuzul A Ibrahim Zheng Guo Xuebing Xu | 2008 | Journal of the American Oil Chemists'' Society2008，85，1： | 1 |
| 14 | Production of structured phospholipids by lipase-catalyzed acidolysis: optimization using response surface methodology显示文摘 | Peng Lifeng Xu Xuebing Mu Huiling | 2002 | Enzyme and Microbial Technology2002，31，： | 1 |
| 15 | Comprehensive Analysis of Peripheral Blood Lymphocytes in 76 Women with Recurrent Miscarriage before and after Lymphocyte Immunotherapy显示文摘 | Peiyan Liang Meilan Mo Guan‐Gui Li Biao Yin Jing Cai Tonghua Wu Xuebing He Xu Zhang Yong Zeng | 2012 | Am J Reprod Immunol2012，，2： | 1 |
| 16 | Enzymaticproduction of alkyl esters through alcoholysis: a critical evaluation oflipases and alcohols显示文摘 | DENG Li XU Xuebing HARALDSSON G G | 2005 | J Am Oil Chem Soc2005，82，5： | 1 |
| 17 | Enzymatic enrichment of long chain polyunsaturated fatty acids from fish oils显示文摘 | Dequen Zhou Xuebing Xu | 2000 | Food Science2000，21，： | 1 |
| 18 | Production of specific-structured triacylglycerols by lipase-catalyzed reactions:a review显示文摘 | | 2000 | Eur J Lipid Sci Technol2000，102，： | 1 |
| 19 | Enzymatic modification of phospholipids for functional applications and human nutrition显示文摘 | Zheng Guo Anders F. Vikbjerg Xuebing Xu | 2005 | Biotechnology Advances2005，，3： | 1 |
| 20 | Production of structured phospholipids by lipase-catalyzed acidolysis:optimization using response surface methodology显示文摘 | Peng Lifeng Xu Xuebing Mu Huiling | 2002 | Enzyme and Microbial Technology2002，31，： | 1 |
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