|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Spatial-temporal characteristics of lake area variations in Hoh Xil region from 1970 to 2011显示文摘As one of the areas with numerous lakes on the Tibetan Plateau, the Hoh Xil region plays an extremely important role in the fragile plateau eco-environment. Based on topographic maps in the 1970 s and Landsat TM/ETM+ remote sensing images in the 1990 s and the period from 2000 to 2011, the data of 83 lakes with an area above 10 km2 each were obtained by digitization method and artificial visual interpretation technology, and the causes for lake variations were also analyzed. Some conclusions can be drawn as follows.(1) From the 1970 s to 2011, the lakes in the Hoh Xil region firstly shrank and then expanded. In particular, the area of lakes generally decreased during the 1970s–1990s. Then the lakes expanded from the 1990 s to 2000 and the area was slightly higher than that in the 1970 s. The area of lakes dramatically increased after 2000.(2) From 2000 to 2011, the lakes with different area ranks in the Hoh Xil region showed an overall expansion trend. Meanwhile, some regional differences were also discovered. Most of the lakes expanded and were widely distributed in the northern, central and western parts of the region. Some lakes were merged together or overflowed due to their rapid expansion. A small number of lakes with the trend of area decrease or strong fluctuation were scattered in the central and southern parts of the study area. And their variations were related to their own supply conditions or hydraulic connection with the downstream lakes or rivers.(3) The increase in precipitation was the dominant factor resulting in the expansion of lakes in the Hoh Xil region. The secondary factor was the increase in meltwater from glaciers and frozen soil due to climate warming. | YAO Xiaojun LIU Shiyin LI Long SUN Meiping LUO Jing | 2014 | Journal of Geographical Sciences2014，24，4： | 14 |
| 2 | BRAF^(V600E) vs. TIRADS in predicting papillary thyroid cancers in Bethesda system Ⅰ, Ⅲ, and Ⅴ nodules显示文摘Objective: Bethesda System for Reporting Thyroid Cytopathology(BSRTC) categories Ⅰ, Ⅲ, and Ⅴaccount for a significant proportion of fine needle aspiration cytology(FNAC) diagnoses. This study aimed to compare the diagnostic efficacy of BRAF^(V600E) mutation and the Thyroid Imaging Reporting and Data System(TIRADS) classification in differentiating papillary thyroid cancers(PTCs) from benign lesions among BSRTC I, III, and V nodules.Methods: A total of 472 patients with 479 nodules were enrolled in this prospective study. Ultrasound, BRAF^(V600E) mutation testing, and FNAC were performed in each nodule, followed by surgery or regular ultrasound examination.Results: In the BSRTC I category, BRAF^(V600E) showed similar sensitivity, higher specificity, and lower accuracy when compared with TIRADS. In the BSRTC III/V category, the sensitivity, specificity, and accuracy of BRAF^(V600E) were similar to those of TIRADS. In comparison to BRAF^(V600E) alone, the combination of the two methods significantly improved sensitivity(BSRTC Ⅰ:93.6% vs. 67.7%, P < 0.01; BSRTC Ⅲ: 93.8% vs. 75.0%, P < 0.01; BSRTC V: 96.0% vs. 85.3%, P < 0.001). When compared with TIRADS alone, the combination improved sensitivity in BSRTC Ⅰ nodules(93.6% vs. 74.2%, P < 0.05), increased sensitivity and decreased accuracy in BSRTC III nodules(93.8% vs. 75.0%, P < 0.01, 91.0% vs. 93.6%, P < 0.01), and improved both sensitivity and accuracy in BSRTC V nodules(96.0% vs. 82.0%, P < 0.001; 94.2% vs. 81.3%, P < 0.001).Conclusions: BRAF^(V600E) exhibited higher specificity and lower accuracy compared with TIRADS in BSRTC Ⅰ nodules, while the two methods showed similar diagnostic value in BSRTC Ⅲ/Ⅴ nodules. The combination of the two methods distinctly improved sensitivity in the diagnosis of PTCs in BSRTC Ⅰ, Ⅲ, and Ⅴ nodules. | Ya Wu Ting Xu Xingyue Cao Xin Zhao Hongyan Deng Jianxiang Wang Xiao Li Qing Yao Xinhua Ye Meiping Shen Xiaohong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 9 |
| 3 | Hydrological processes of glacier and snow melting and runoff in the Urumqi River source region, eastern Tianshan Mountains, China显示文摘水文学过程被比较,有或没有分泌物上的降水的影响,到在 Urumqi 河来源区域识别 glacierized 和 non-glacierized 集水之间的差别在东方 Tianshan 山的北斜坡上,在在 2011 的融化的季节(MaySeptember ) 期间。学习基于在 10-min 间隔,在 15-min 间隔观察的气象学的数据,并且冰河从空冰斗, Zongkong,和计量车站的 Urumqi 冰河 No.1 融化和雪观察观察的水文学数据。结果显示分泌物在三之中显著地不同计量车站。每日的分泌物多于在计量车站的冰河 No.1 的夜里的分泌物,它形成对照,模式在计量车站的 Zongkong 和空冰斗观察了。在在三个计量车站的分泌物有一个清楚的每日的变化,与在山峰分泌物的大小和持续时间的差别。当降水没被考虑时,在最大的分泌物和最高的温度之间的时间落后是在分别地计量车站的冰河 No.1,空冰斗,和 Zongkong 的 13 h, 1016 h,和 511 h。当降水被考虑时,相应时间落后分别地是 01 h, 13 h,和 67 h。因此,从到融合的分泌物的产生的持续时间在 glacierized 集水是最短的并且在被雪主要盖住的集水最长。降水什么时候被考虑,也被显示出从到融合的分泌物的产生的水文学过程弄短。在三之中在分泌物影响变化计量车站的因素是不同的。为冰河 No.1 车站,分泌物被热条件主要在 glacierized 区域控制,并且当温度超过了 5 时,分泌物显示了加速的生长 ? 楷桴 ? 朿丠佩愠摮 ???? 噐? 攠畱癩污湥 ? 潴 ?? ┿瑷倠 ?? 湩眠楥桧 ? 祳瑮敨楳? 愠 ?? 整灭牥瑡牵 ? | SUN Meiping YAO Xiaojun LI Zhongqin ZHANG Mingjun | 2015 | Journal of Geographical Sciences2015，25，2： | 6 |
| 4 | Nonpharmaceutical interventions contribute to the control of COVID-19 in China based on a pairwise model显示文摘Nonpharmaceutical interventions(NPIs),particularly contact tracing isolation and household quarantine,play a vital role in effectively bringing the Coronavirus Disease 2019(COVID-19)under control in China.The pairwise model,has an inherent advantage in characterizing those two NPIs than the classical well-mixed models.Therefore,in this paper,we devised a pairwise epidemic model with NPIs to analyze COVID-19 outbreak in China by using confirmed cases during February 3rde22nd,2020.By explicitly incorporating contact tracing isolation and family clusters caused by household quarantine,our model provided a good fit to the trajectory of COVID-19 infections.We calculated the reproduction number R=1.345(95%CI:1.230-1.460)for Hubei province and R=1.217(95%CI:1.207-1.227)for China(except Hubei).We also estimated the peak time of infections,the epidemic duration and the final size,which are basically consistent with real observation.We indicated by simulation that the traced high-risk contacts from incubated to susceptible decrease under NPIs,regardless of infected cases.The sensitivity analysis showed that reducing the exposure of the susceptible and increasing the clustering coefficient bolster COVID-19 control.With the enforcement of household quarantine,the reproduction number R and the epidemic prevalence declined effectively.Furthermore,we obtained the resumption time of work and production in China(except Hubei)on 10th March and in Hubei at the end of April 2020,respectively,which is broadly in line with the actual time.Our results may provide some potential lessons from China on the control of COVID-19 for other parts of the world. | Xiao-Feng Luo Shanshan Feng Junyuan Yang Xiao-Long Peng Xiaochun Cao Juping Zhang Meiping Yao Huaiping Zhu Michael Y.Li Hao Wang Zhen Jin | 2021 | Infectious Disease Modelling2021，6，1： | 2 |
| 5 | Serotonin 1A receptor inhibits the status epilepticus induced by lithium-pilocarpine in rats显示文摘Status epilepticus(SE) is a life-threatening neurological emergency associated with a high mortality rate. The serotonin 1A(5-HT1A) receptor is a possible target for the treatment of SE, but its role in animal models and the precise area of brain involved remain controversial. The hippocampus is a candidate site due to its key role in the development of SE and the existence of a high density of 5-HT1A receptors. Therefore, we investigated the effects of subcutaneous and intrahippocampal activation of 5-HT1A receptors in lithium-pilocarpine-induced SE, and tested whether the hippocampus is a true effector site. We developed SE in male Sprague-Dawley rats by giving lithium chloride(LiCl; 3 meq/kg, i.p.) 22–24 h prior to pilocarpine(25 mg/kg, i.p.), and found that 8-OH-DPAT, a 5-HT1A receptor agonist administered subcutaneously(s.c.) at 0.5 or 1.0 mg/kg 1 h before pilocarpine injection increased the latency to the first epileptiform spikes, the electrographic SE, and the behavioral generalized seizures(GS), while reducing the total EEG seizure time(P <0.01). The duration of GS was shortened only by 1.0 mg/kg 8-OH-DPAT s.c.(P <0.05). All these effects were inhibited by combined administration of WAY-100635(1.0 mg/kg, s.c.)(P <0.05), an antagonist of the 5-HT1A receptor, but WAY-100635 alone and low doses of 8-OHDPAT(0.01 and 0.1 mg/kg) did not alter seizure activity. Furthermore, intrahippocampal 8-OH-DPAT only shortened the GS duration(P <0.05). These findings imply that the 5-HT1A receptor is a promisingtherapeutic target against the generation and propagation of SE, and hippocampal receptors are involved in reducing the seizure severity. | Yi Yang Yi Guo Yifang Kuang Shan Wang Yan Jiang Yao Ding Shuang Wang Meiping Ding | 2014 | Neuroscience Bulletin2014，30，3： | 1 |
| 6 | Monotone method for first order functional differential equations with retardation and anticipation显示文摘 | YAO Meiping ZHAO Aimin YAN J urang | 2009 | Nonlinear Analysis2009，71，： | 1 |
| 7 | Periodic bound-ary value problems of second-order impulsive differen-tial equations显示文摘 | Yao Meiping Zhao Aimin Yan Jurang | 2009 | Nonl Anal2009，70，1： | 1 |
| 8 | Establishment of an experimental human lung adenocarcinoma cell line SPC-A-1BM with high bone metastases potency by 99m Tc-MDP bone scintigraphy显示文摘 | Shunfang Yang Qianggang Dong Ming Yao Meiping Shi Jianding Ye Langxiang Zhao Jianzhong Su Weiyong Gu Wenhui Xie Kankan Wang Yanzhi Du Yao Li Yan Huang | 2009 | Nuclear Medicine and Biology2009，，3： | 1 |
| 9 | Monotone method for first order functional differential equations with retardation and anticipation显示文摘 | YAO Meiping ZHAO Aimin YAN Jurang | 2009 | Nonlinear Analysis2009，71，： | 1 |
| 10 | Cilostazol as an alternative to aspirin after ischaemic stroke: a randomised, double-blind, pilot study显示文摘 | Yining Huang Yan Cheng Jiang Wu Yansheng Li En Xu Zhen Hong Zhengyi Li Weiwei Zhang Meiping Ding Xuguang Gao Dongsheng Fan Jinsheng Zeng Kasing Wong Chuanzhen Lu Jiangxi Xiao Chen Yao | 2008 | Lancet Neurology2008，，6： | 1 |
| 11 | Monotone method for first order functional differential equations with retardation and anticipation 显示文摘 | Yao Meiping Zhao Aimin Yan Jurang | 2009 | Nonlinear Analysis2009，71，： | 1 |
| 12 | Cilostazol as an alternative to aspirin after ischaemic stroke: a randomised, double-blind, pilot study显示文摘 | Yining Huang Yan Cheng Jiang Wu Yansheng Li En Xu Zhen Hong Zhengyi Li Weiwei Zhang Meiping Ding Xuguang Gao Dongsheng Fan Jinsheng Zeng Kasing Wong Chuanzhen Lu Jiangxi Xiao Chen Yao | 2008 | Lancet Neurology2008，，6： | 1 |
| 13 | Removal of Cr3+ from aqueous solution by biosorption with aerobic granules显示文摘 | Yao Lei Ye Zhengfang Tong Meiping | 2008 | Journal of Hazardous Materials2008，165，123： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员