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| 1 | Excessive portal flow causes graft failure in extremely small-for-size liver transplantation in pigs显示文摘AIM: To evaluate the effects of a portocaval shunt on the decrease of excessive portal flow for the prevention of sinusoidal microcirculatory injury in extremely smallfor-size liver transplantation in pigs.METHODS: The right lateral lobe of pigs, i.e. the 25%of the liver, was transplanted orthotopically. The pigs were divided into two groups: graft without portocaval shunt (n = 11) and graft with portocaval shunt (n=11).Survival rate, portal flow, hepatic arterial flow, and histological findings were investigated.RESULTS: In the group without portocaval shunt, all pigs except one died of liver dysfunction within 24 h after transplantation. In the group with portocaval shunt,eight pigs survived for more than 4 d. The portal flow volumes before and after transplantation in the group without portocaval shunt were 118.2±26.9 mL/min/100 g liver tissue and 270.5±72.9 mL/min/100 g liver tissue,respectively. On the other hand, in the group with portocaval shunt, those volumes were 124.2±27.8 mL/min/100 g liver tissue and 42.7±32.3 mL/min/100 g liver tissue, respectively (P<0.01). As for histological findings in the group without portocaval shunt, destruction of the sinusoidal lining and bleeding in the peri-portal areas were observed after reperfusion, but these findings were not recognized in the group with portocaval shunt.CONCLUSION: These results suggest that excessive portal flow is attributed to post transplant liver dysfunction after extreme small-for-size liver transplantation caused by sinusoidal microcirculatory injury. | Hong-Sheng Wang Nobuhiro Ohkohchi Yoshitaka Enomoto Masahiro Usuda Shigehito Miyagi Takeshi Asakura Hiroo Masuoka Takashi Aiso Keisuke Fukushima Tomohiro Narita Hideyuki Yamaya Atsushi Nakamura Satoshi Sekiguchi Naoki Kawagishi Akira Sato Susumu Satomi | 2005 | World Journal of Gastroenterology2005，11，44： | 8 |
| 2 | Optimal calibration scheme for map-based control of diesel engines显示文摘Map-based control has the advantage of a simple control structure. However, in the case of a complex plant, calibrating the map is difficult. Calibration methodology using plant model is increasing in engine calibration industries. However, the models are for steady-state operation and cannot simulate at transient operation well. This study introduces the dynamic empirical model and applies the transient corrective function of an electronic control unit to simulate more realistic behavior. The optimization problem for calibrating maps of diesel engines is constructed, and the formulation of cost function and constraints is discussed. Consequently, the proposed calibration scheme can find an optimal map in satisfied constraints.Finally, the optimized maps are validated using mass production diesel engines. | Yui NISHIO Yutaka MURATA Yukihisa YAMAYA Masato KIKUCHI | 2018 | Science China(Information Sciences)2018，61，7： | 3 |
| 3 | Randomized phase II trial comparing nitroglycerin plus vinorelbine and cisplatin with vinorelbine and cisplatin alone in previously untreated stage IIIB/IV non-small-cell lung cancer 显示文摘 | Yasuda H Yamaya M Nakayama K | 2006 | J Clin Oncol2006，24，4： | 1 |
| 4 | The usefulness of thecollagen and elastin sponge derived from salmon as an artificialdermis and scaffold for tissue engineering 显示文摘 | Matsumoto Y Ikeda K Yamaya Y | 2011 | Biomed Res2011，32，1： | 1 |
| 5 | Sleep patterns andmortality among elderly patients in a geriatric hospital 显示文摘 | Manabe K Matsui T Yamaya M | 2000 | Gerontology2000，46，6： | 1 |
| 6 | Low-energy extracorporeal shock wave therapy promotes vascular endothelial growth factor expression and improves locomotor recovery after spinal cord injury 显示文摘 | Yamaya S Ozawa H Kanno H | 2014 | J Neurosurg2014，121，6： | 1 |
| 7 | Glow-plug assisted cold start of premixed compression ignition natural gas engines 显示文摘 | Yamaya Yukihisa Takemoto Takaaki Furutani Masahiro | 2003 | Journal of KONES Internal Combustion Engines2003，10，12： | 1 |
| 8 | Sleep patterns and mortality am ong elderly patients in a geriatric hospital显示文摘 | Matsui T Yamaya M | 2000 | Gerontology2000，46，6： | 1 |
| 9 | Sleep patterns and mortality among elderly patients in a geriatric hospital显示文摘 | Manabe K Matsui T Yamaya M | 2000 | Gerontology2000，46，6： | 1 |
| 10 | Intervention to prevent pneumonia among old adult显示文摘 | Yamaya M Yanai M Ohrui T et at | 2001 | J Am Geriatr Soc2001，49，： | 1 |
| 11 | Compartment of nitrogen assimila- tion in higher plants 显示文摘 | SECHLEY K A YAMAYA T OAKS A | 1992 | Int Rev Cytol1992，134，： | 1 |
| 12 | Carboeisteine reduces frequency of common colds and exacerbations in patients with chronic obstructive pulmonary disease 显示文摘 | Yasuda H Yamaya M Sasaki T | 2006 | J Am Gefiatr Soe2006，54，： | 1 |
| 13 | Estrogen receptor alpha and beta are prognostic factors in non-small cell lung cancer显示文摘 | Kawai H Ishii A Washiya K Konno T Kon H Yamaya C | 2005 | Clin Cancer Res2005，11，14： | 1 |
| 14 | Rhinovirus and asthma显示文摘 | Yamaya M Sasaki H | 2003 | Viral Immunol2003，16，： | 1 |
| 15 | Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema显示文摘 | Yamada N Yamaya M Okinaga S | 2000 | Am J Hum Genet2000，66，： | 1 |
| 16 | Virus infection - induced bronchial asthma exacerbation显示文摘 | YAMAYA M | 2012 | Pulm Med2012，2012，83： | 1 |
| 17 | 显示文摘 | Yamada N Yamaya M Okinaga S | 2000 | Am J Hum Genet2000，66，： | 1 |
| 18 | Cellular eompartmentation of ammonium assimilation in rice and barley显示文摘 | Tobin A K Yamaya T | 2001 | J Exp Bot2001，52，： | 1 |
| 19 | Microsatellitepolymorphism in the heine oxygenase-1 gene promoter is associated with suscepfibilityto emphysema显示文摘 | Norihlro Y Yamaya M Okinaga S | 2000 | Hum Cenet2000，66，： | 1 |
| 20 | Circulating cytokines and hormones with immunosuppressive but neutrophil-priming potentials rise after endurance exercise in humans显示文摘 | Katsuhiko Suzuki Mutsuo Yamada Shigeyoshi Kurakake Noriyoshi Okamura Kanemitsu Yamaya Qiang Liu Satoru Kudoh Kenji Kowatari Shigeyuki Nakaji Kazuo Sugawara | 2000 | European Journal of Applied Physiology2000，，4： | 1 |
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