|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Transcriptome analysis reveals long noncoding RNAs involved in fiber development in cotton (Gossypium arboreum)显示文摘Long noncoding RNAs(lnc RNAs)play important roles in various biological regulatory processes in yeast,mammals,and plants.However,no systematic identification of lnc RNAs has been reported in Gossypium arboreum.In this study,the strand-specific RNA sequencing(ss RNA-seq)of samples from cotton fibers and leaves was performed,and lnc RNAs involved in fiber initiation and elongation processes were systematically identified and analyzed.We identified 5,996 lnc RNAs,of which 3,510 and 2,486 can be classified as long intergenic noncoding RNAs(linc RNAs)and natural antisense transcripts(lnc NAT),respectively.Linc RNAs and lnc NATs are similar in many aspects,but have some differences in exon number,exon length,and transcript length.Expression analysis revealed that 51.9%of linc RNAs and 54.5%of lnc NATs transcripts were preferentially expressed at one stage of fiber development,and were significantly highly expressed than protein-coding transcripts(21.7%).During the fiber and rapid elongation stages,rapid and dynamic changes in lnc RNAs may contribute to fiber development in cotton.This work describes a set of lnc RNAs that are involved in fiber development.The characterization and expression analysis of lnc RNAs will facilitate future studies on their roles in fiber development in cotton. | Changsong Zou Qiaolian Wang Cairui Lu Wencui Yang Youping Zhang Hailiang Cheng Xiaoxu Feng Mtawa Andrew Prosper Guoli Song | 2016 | Science China(Life Sciences)2016，59，2： | 9 |
| 2 | Effects of modified Wenjing decoction on microcirculation in reproductive organs in rats with symptom patterns of cold coagulation and blood stasis显示文摘OBJECTIVE: To investigate the relationship between symptom patterns of cold coagulation and blood stasis(CCBS) and microcirculation disturbance. In addition, we determined the efficacy of modified Wenjing decoction(WJD) for the treatment of CCBS.METHODS: CCBS was induced in rats with an icewater bath treatment. The ovarian function, microvascular and circulatory status of reproductive organs, and function of local microvascular endothelial cells(VECs) and vascular smooth muscle cells(VSMCs) were evaluated.RESULTS: Ovarian dysfunction was observed in the rats with CCBS. It was characterized by the presence of an estrous cycle disorder and a decrease in reproductive hormone levels. Microvascular circulation disorders were associated with an imbalance in vasoconstriction, relaxation substances, nitric oxide, abnormal blood flow in whole blood, and decreased blood flow in the auricle and uterus. VECs were damaged, and VSMCs contracted and proliferated in ovarian and uterine tissues.CONCLUSION: Our findings suggest that the dysfunctional reproductive organs observed in gynecological CCBS may be closely related to the microcirculation disturbance of local tissues, microvascular contraction, and vascular remodeling. Modified WJD can be used to treat CCBS by improving microcirculation in reproductive organs. | Wang Di Cheng Xiumei Fang Huimin Ren Yanqing Li Xinhua Ren Weiwei Xue Bing Yang Cairui | 2020 | Journal of Traditional Chinese Medicine2020，40，2： | 4 |
| 3 | Efficient multi-scale community search method based on spectral graph wavelet显示文摘Community search is an important problem in network analysis,which has attracted much attention in recent years.As a query-oriented variant of community detection problem,community search starts with some given nodes,pays more attention to local network structures,and gets personalized resultant communities quickly.The existing community search method typically returns a single target community containing query nodes by default.This is a strict requirement and does not allow much flexibility.In many realworld applications,however,query nodes are expected to be located in multiple communities with different semantics.To address this limitation of existing methods,an efficient spectral-based Multi-Scale Community Search method(MSCS)is proposed,which can simultaneously identify the multi-scale target local communities to which query node belong.In MSCS,each node is equipped with a graph Fourier multiplier operator.The access of the graph Fourier multiplier operator helps nodes to obtain feature representations at various community scales.In addition,an efficient algorithm is proposed for avoiding the large number of matrix operations due to spectral methods.Comprehensive experimental evaluations on a variety of real-world datasets demonstrate the effectiveness and efficiency of the proposed method. | Cairui YAN Huifang MA Qingqing LI Fanyi YANG Zhixin LI | 2023 | Frontiers of Computer Science2023，17，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员