|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Longitudinal distributions of two formation pathways of biogenic gases in continental deposits: A case study from Sebei 1 gas field in the Qaidam Basin, western China显示文摘The distribution of two formation pathways of biogenic methane, acetate fermentation and reduction of CO2, has been extensively studied. In general, CO2 reduction is the dominate pathway in marine envi- ronment where acetate is relatively depleted because of SRB consuming. While in terrestrial freshwater or brackish environment, acetate fermentation is initially significant, but decreases with increasing buried depth. In this paper, character of biogenic gases is profiled in the XS3-4 well of the Sebei 1 gas field in the Sanhu depression, Qaidam Basin. It indicates that those two pathways do not change strictly with increasing buried depth. CO2 reduction is important near the surface (between 50 m and 160 m), and at the mesozone (between 400 and 1650 m). While acetate fermentation is the primary pathway at two zones, from 160 to 400 m and from 1650 to 1700 m. δ 13C of methane generated in those two acetate fermentation zones varies greatly, owing to different sediment circumstances. At the sec- ond zone (160-400 m), δ 13C1 ranges from ?65‰ to ?30‰ (PDB), because the main deposit is mudstone and makes the circumstance confined. At the fourth zone of the well bottom (1650-1700 m), δ 13C1 is lighter than ?65‰ (PDB). Because the deposit is mainly composed of siltstone, it well connects with outer fertile groundwater and abundant nutrition has supplied into this open system. The high con- centration of acetate is a forceful proof. δ 13C of methane would not turn heavier during fermentation, owing to enough nutrition supply. In spite of multi-occurrence of acetate fermentation, the commercial gas accumulation is dominated by methane of CO2-reduction pathway. A certain content of alkene gases in the biogenic gases suggests that methanogensis is still active at present. | SHUAI YanHua ZHANG ShuiChang ZHAO WenZhi SU AiGuo WANG HuiTong | 2007 | Science China Earth Sciences2007，50，2： | 5 |
| 2 | Geochemical evidence for strong ongoing methanogenesis in Sanhu region of Qaidam Basin显示文摘Sanhu depression of Qaidam Basin is the largest biogenic gas production region in China.Headspace samples were collected from two wells in this region,and hydrogen and propylene compounds were detected in these samples with a certain concentration.The stable hydrogen isotope ratio of H 2 is relatively light (-700‰--820‰).The stable carbon isotope ratio of propylene ranges from -27‰ to -40‰,which coincides with the rule of change of the stable carbon isotope of kerogen at the corresponding horizon.The characteristic analysis of sediments,structures,and Ar and He components in the region indicates that these microelement compounds are the product of degradation of organic substances by microorganisms,rather than from the mantle source,inorganic reaction or other sources.Detection of these components provides solid evidence for the strong ongoing methanogenesis in this region. | YanHua Shuai ShuiChang Zhang AiGuo Su HuiTong Wang BaoYuan Cai Hui Wang | 2010 | Science China Earth Sciences2010，53，1： | 5 |
| 3 | Environmental chemical stressors as epigenome modifiers:a new horizon in assessment of toxicological effects显示文摘In eukaryotic cells, chromatin transformation from euchromatin into heterochromatin as a means of controlling gene expression and replication has been known as the ‘‘accessibility hypothesis' '. The interplay of epigenetic changes including histone modifications, DNA methylation, RNA interference(RNAi) and other func- tional epigenetic components are intricate. It is believed that these changes are well-programmed, inherited and can be modified by environmental contaminant stressors. Environmentally-driven epigenetic alterations during development, e.g. embryonic, foetal or neonatal stage, may influence disease susceptibility in adulthood. Therefore, understanding how epigenome modifications develop in response to environmental chemicals and, how epigenetic-xenobiotic interactions influence human health will shed new insights into gene-environment interactions in the epidemiology of several diseases including cancer. In this review, we consider studies of chemical modifiers including nutritional and xenobiotic effects on epigenetic components in vitro or in vivo. By examining the most-studied epigenome modifications and how their respective roles are interlinked, we highlight the central role of xenbiotic- modified epigenetic mechanisms. A major requirement will be to study and understand effects following environmentally-relevant exposures. We suggest that the study of epigenetic toxicology will open up new opportunities to devise strategies for the prevention or treatment of at-risk populations. | Heqing Shen F.L.Martin Yanhua Su | 2014 | Chinese Science Bulletin2014，59，4： | 2 |
| 4 | Kinetic Modeling the Formation of Low-mature Gases and Analysis of the Possibility to Be Accumulated显示文摘摘要:目前,浅气体在探索和生产由于低费用收到了许多注意。低成熟的气体作为到浅气体的一重要起源,转弯是一个重要研究话题。低成熟的气体的现在的理解在一些地质的案例以内被限制,并且很少实验室学习被报导了。因此,低成熟的气体的潜力和人物是别放晴到现在。这里,二件早熟的样品(一煤和另外的页岩) 是在一个金限制系统的 pyrolyzed。包括烃气体和非烃气体的气体的部件被分析。基于运动建模,低成熟的气体的形成被建模。结果证明在低成熟舞台期间,大约 178 mL/gTOC 气体从煤从页岩和 100 mL/gTOC 被产生。三分之二是象 H2S 和 CO2 那样的非烃气体到四分之三产生气体。为二件样品的 C15 的全部的收益是几乎一样, 3040 mL/gTOC,而是单个气体的烃是不同的。页岩有低得多的 C1 但是更高的 C25,而煤有更高的 C1 但是更低的 C25。在低成熟的舞台期间形成的烃气体是很湿的。甲烷的稳定的碳同位素比率从 ?40% 到 ?50%(PDB ) ,在有为以前的研究人员总结的低成熟的气体的实验标准的好坚固性。产生人物建议低成熟的气体能被积累形成一座经济煤气的水库,但是他们中的大多数仅仅作为联系气体发生。 | SHUAI Yanhua WANG Hui ZHANG Shuichang SU Aiguo | 2008 | Acta Geologica Sinica(English Edition)2008，82，3： | 2 |
| 5 | Source of nutrient substrates for microbes in deep biosphere and characteristics of biogenic gas source rock显示文摘To understand the biogas formation in geological basins, the present work investigated the reactive organic matter in sediments of the Sanhu depression of Qaidam Basin, a prolific region of biogenic gases with a proved reserve of 300 bil steres. The ROC (reactive organic carbon) was obtained by ultrasonic extraction from sediment samples in the solution of 6 mol/L HCl and 5% K2SO4. To investigate the effect of early diagenesis, parts of the samples were heated at 80°C before extraction. The results showed that the ROC content at a constant temperature decreased with increasing burial depths, which should be attributed to the microbial consumption. For the same sample, the ROC content heated at 80°C was dramatically higher than the unheated. The increment of the ROC content for some samples was as high as 200% in the experiment. The dramatically increasing ROC by thermal action should be the major nutrient substrate for the deep biospheres in most geological basins. There is a positive correlation between the reactive organic carbon (ROC) and the traditional insoluble organic carbon (TOC), not only for its absolute content of the ROC, but also for the 'ROC' produced in thermal action, all of these are clearly related with TOC. These data showed that higher abundance of organic matter can contribute more to the reactive organic matter, and is more favorable to the formation of biogenic gases. In the Sanhu depression of Qaidam Basin, more than 85% of the biogenic gas reserves occur in the lower layers (K5-K13) with a relatively high abundance of organic matter. The exploration has provided further evidence that deposits with higher abundance of organic matter are effective biogas source rocks. | SHUAI YanHua ZHANG ShuiChang CHEN JianPing SU AiGuo | 2010 | Science China Earth Sciences2010，53，8： | 2 |
| 6 | Feasibility of Booster Vaccination in High-Risk Populations for Controlling Coronavirus Variants—China,2021显示文摘Introduction:Vaccination booster shots are completely necessary for controlling breakthrough infections of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)in China.The study aims to estimate effectiveness of booster vaccines for high-risk populations(HRPs).Methods:A vaccinated Susceptible-Exposed-Symptomatic-Asymptomatic-Recovered/Removed(SEIAR)model was developed to simulate scenarios of effective reproduction number(Reff)from 4 to 6.Total number of infectious and asymptomatic cases were used to evaluated vaccination effectiveness.Results:Our model showed that we could not prevent outbreaks when covering 80%of HRPs with booster unless Reff=4.0 or the booster vaccine had efficacy against infectivity and susceptibility of more than 90%.The results were consistent when the outcome index was confirmed cases or asymptomatic cases.Conclusions:An ideal coronavirus disease 2019(COVID-19)booster vaccination strategy for HRPs would be expected to reach the initial goal to control the transmission of the Delta variant in China.Accordingly,the recommendation for the COVID-19 booster vaccine should be implemented in HRPs who are already vaccinated and could prevent transmission to other groups. | Kangguo Li Zeyu Zhao Hongjie Wei Jia Rui Jiefeng Huang Xiaohao Guo Yichao Guo Shiting Yang Guzainuer Abudurusuli Li Luo Xingchun Liu Yao Wang Jingwen Xu Yuanzhao Zhu Meng Yang TianlongYang Weikang Liu Bin Deng Chan Liu Zhuoyang Li Peihua Li Shanshan Yu Zimei Yang Yanhua Su Benhua Zhao Yan Niu Tianmu Chen | 2021 | China CDC weekly2021，3，50： | 2 |
| 7 | Significance of phytosterol analysis to phytosterolemia diagnosis 显示文摘 | Su Yanhua Wang Zhaoyue Cao Lijuan | 2007 | Chinese Journal of Laboratory Medicine2007，30，2： | 1 |
| 8 | Spatiotemporal cortical activation underlying self-referencial processing evoked by self-hand显示文摘 | Yanhua Su Antao Chen Huazhan Yin Jiang Qiu Jieyu Lv Dongtao Wei Fang Tian Shen Tu Ting Wang | 2010 | Biological Psychology2010，，2： | 1 |
| 9 | Different levels of thyroid hormones between impaired fasting glucose and impaired glucose tolerance: free T3 affects the prevalence of impaired fasting glucose and impaired glucose tolerance in opposite ways显示文摘 | Su Jing Ding Xiaoying Xu Ying Liu Rui Gu Mingyu Chen Yuting Yin Yanhua Wang Yufan Sun Haiyan Peng Yongde | 2014 | Clin Endocrinol2014，，6： | 1 |
| 10 | Transgenic tomato overexpressing ath-miR399d has enhanced phosphorus accumulation through increased acid phosphatase and proton secretion as well as phosphate transporters显示文摘 | Nan Gao Yanhua Su Ju Min Weishou Shen Weiming Shi | 2010 | Plant and Soil (-)2010，，1： | 1 |
| 11 | MFL testing of omni-directional cracks in steel strip using strong longitudinal magnetization显示文摘 | Kai Song Yihua Kang Yanhua Sun Chen Qiu Jianke Su | | 2010 (3,4)0，，： | 1 |
| 12 | Arabidopsis under ammonium over-supply: Characteristics of ammonium toxicity in relation to the activity of ammonium transporters显示文摘Because of highly intensive farming practices, crop plants could suffer relatively long terms of ammonium(NH4+) excess stress introduced by overdose application of nitrogen fertilizers. However, the lack of sufficient understanding of plant responses to NH4+excess stress impairs the detection of effective solutions to this problem. The present work examined the biological influences of over-supplied NH4+in Arabidopsis thaliana using two mutant lines each with an ammonium transporter(AMT) gene(AtAMT1;1 or AtAMT1;3) knocked out. Our results indicated that lacking one of the major components of root NH4+-absorbing systems significantly alleviated the toxicity effects on Arabidopsis plants by reducing the accumulation of free NH4+, suggesting that persistent absorption of NH4+through AMT was the main cause of excessive accumulation of free NH4+in the plants. Shading treatment led to a reduced transpirational driving force and thereby constrained the accumulation of toxic NH4+in the plants, finally resulting in higher NH4+-promoted growth in the wild type(WT). Under the shading treatment, the amt1;1 and amt1;3 mutant plants acquired insufficient NH4+and showed reduced growth when compared with the WT. Furthermore, the foliar application of sucrose notably alleviated the inhibitory effects on plant growth in the WT but had no effect on either the amt1;1 or amt1;3 mutant plants, indicating that carbon scarcity associated with NH4+excess is probably a major cause of NH4+toxicity in plants. Accordingly,increasing carbon source could be a potentially effective approach that alleviates the inhibition caused by NH4+excess and increases nitrogen use efficiency under NH4+over-supply. | Yi LI Jinyan ZHOU Dongli HAO Shunying YANG Yanhua SU | 2020 | Pedosphere2020，30，3： | 1 |
| 13 | Fabri- cation of alternate stacking MnO2/MoS2 layered nano- hybrid by a sonoehemistry technology 显示文摘 | SU Zhikui CUI Yanhua TANG Xiuhua | 2008 | Chinese Journal of Chemistry2008，26，3： | 1 |
| 14 | Hydrogenolysis of cellulose to C4–C7 alcohols over bi-functional CuO–MO/Al 2 O 3 (M=Ce, Mg, Mn, Ni, Zn) catalysts coupled with methanol reforming reaction显示文摘 | Yanhua Wu Fangna Gu Guangwen Xu Ziyi Zhong Fabing Su | 2013 | Bioresource Technology2013，，： | 1 |
| 15 | Simulating potential outbreaks of Delta and Omicron variants based on contact-tracing data:A modelling study in Fujian Province,China显示文摘Although studies have compared the relative severity of Omicron and Delta variants by assessing the relative risks,there are still gaps in the knowledge of the potential COVID-19 burden these variations may cause.And the contact patterns in Fujian Province,China,have not been described.We identified 8969 transmission pairs in Fujian,China,by analyzing a contact-tracing database that recorded a SARS-CoV-2 outbreak in September 2021.We estimated the waning vaccine effectiveness against Delta variant infection,contact patterns,and epidemiology distributions,then simulated potential outbreaks of Delta and Omicron variants using a multi-group mathematical model.For instance,in the contact setting without stringent lockdowns,we estimated that in a potential Omicron wave,only 4.7%of infections would occur in Fujian Province among individuals aged>60 years.In comparison,58.75%of the death toll would occur in unvaccinated individuals aged>60 years.Compared with no strict lockdowns,combining school or factory closure alone reduced cumulative deaths of Delta and Omicron by 28.5%and 6.1%,respectively.In conclusion,this study validates the need for continuous mass immunization,especially among elderly aged over 60 years old.And it confirms that the effect of lockdowns alone in reducing infections or deaths is minimal.However,these measurements will still contribute to lowering peak daily incidence and delaying the epidemic,easing the healthcare system's burden. | Yichao Guo Wenjing Ye Zeyu Zhao Xiaohao Guo Wentao Song Yanhua Su Benhua Zhao Jianming Ou Yanqin Deng Tianmu Chen | 2023 | Infectious Disease Modelling2023，8，1： | 1 |
| 16 | Modelling the Emerging COVID-19 Epidemic and Estimating Intervention Effectiveness—Taiwan,China,2021显示文摘Introduction:The coronavirus disease 2019(COVID-19)pandemic recently affected Taiwan,China.This study aimed to calculate the transmissibility of COVID-19 to predict trends and evaluate the effects of interventions.Methods:The data of reported COVID-19 cases was collected from April 20 to May 26,2021,which included daily reported data(Scenario I)and reported data after adjustment(Scenario II).A susceptibleexposed-symptomatic-asymptomatic-recovered model was developed to fit the data.The effective reproductive number(Reff)was used to estimate the transmissibility of COVID-19.Results:A total of 4,854 cases were collected for the modelling.In Scenario I,the intervention has already taken some effects from May 17 to May 26(the Reff reduced to 2.1).When the Reff was set as 0.1,the epidemic was projected to end on July 4,and a total of 1,997 cases and 855 asymptomatic individuals would have been reported.In Scenario II,the interventions were projected as having been effective from May 24 to May 26(the Reff reduced to 0.4).When the Reff was set as 0.1,the epidemic was projected to end on July 1,and a total of 1,482 cases and 635 asymptomatic individuals would have been reported.Conclusion:The epidemic of COVID-19 was projected to end after at least one month,even if the most effective interventions were applied in Taiwan,China.Although there were some positive effects of intervention in Taiwan,China. | Weikang Liu Wenjing Ye Zeyu Zhao Chan Liu Bin Deng Li Luo Jiefeng Huang Yao Wang Jia Rui Benhua Zhao Yanhua Su Shenggen Wu Kun Chen Jianming Ou Tianmu Chen | 2021 | China CDC weekly2021，3，34： | 1 |
| 17 | Protective effectsof the Citrus flavanones to PC12 cells against cytotoxicity inducedby hydrogen peroxide显示文摘 | Lu Yanhua Su Mingyuan Huang Haiya | 2010 | Neurosci Lett2010，484，： | 1 |
| 18 | Evaluation of micelles incorporated into thermosensitive hydrogels for intratumoral delivery and controlled release of docetaxel:A dual approach for in situ treatment of tumors显示文摘The in situ gelling hybrid hydrogel system has been reported to effectively concentratechemotherapeutic drugs at the tumor site and sustain their release for a long period. DTX-micelles(docetaxel-loaded mixed micelles) are able to increase the solubility of DTX inwater, and then a high drug loading rate of hydrogels can be achieved by encapsulatingthe docetaxel-loaded mixed micelles into the hydrogels. The thermosensitive nature ofDTX-MM-hydrogels(thermosensitive hydrogels incorporated with docetaxel-loaded mixedmicelles) can accelerate the formation of a depot of this drug-loaded system at the siteof administration. Therefore, the hydrogels provide a much slower release compared withDTX-micelles and DTX-injection. An in vivo retention study has demonstrated that the DTX-MM-hydrogels can prolong the drug retention time and in viv o trials have shown that theDTX-MM-hydrogels have a higher antitumor efficacy and systemic safety. In conclusion, theDTX-MM-hydrogels prepared in this study have considerable potential as a drug deliverysystem, with higher tumor inhibition effects and are less toxic to normal tissues. | Meng Xu Yanhua Mou Mingming Hu Wenxiang Dong Xitong Su Rongxiaa Wu Peng Zhang | 2018 | Asian Journal of Pharmaceutical Sciences2018，13，4： | 1 |
| 19 | Shigellosis seasonality and transmission characteristics in different areas of China: A modelling study显示文摘Objective:In China,the burden of shigellosis is unevenly distributed,notably across various ages and geographical areas.Shigellosis temporal trends appear to be seasonal.We should clarify seasonal warnings and regional transmission patterns.Method:This study adopted a Logistic model to assess the seasonality and a dynamics model to compare the transmission in different areas.The next-generation matrix was used to calculate the effective reproduction number(Reff)to quantify the transmissibility.Results:In China,the rate of shigellosis fell from 35.12 cases per 100,000 people in 2005 to 7.85 cases per 100,000 people in 2017,peaking in June and August.After simulation by the Logistic model,the‘peak time’is mainly concentrated from mid-June to mid-July.China's‘early warning time’is primarily focused on from April to May.We predict the‘peak time’of shigellosis is the 6.30th month and the‘early warning time’is 3.87th month in 2021.According to the dynamics model results,the water/food transfer pathway has been mostly blocked off.The transmissibility of different regions varies greatly,such as the mean Reff of Longde County(3.76)is higher than Xiamen City(3.15),higher than Chuxiong City(2.52),and higher than Yichang City(1.70).Conclusion:The‘early warning time’for shigellosis in China is from April to May every year,and it may continue to advance in the future,such as the early warning time in 2021 is in mid-March.Furthermore,we should focus on preventing and controlling the personto-person route of shigellosis and stratified deploy prevention and control measures according to the regional transmission. | Zeyu Zhao Meng Yang Jinlong Lv Qingqing Hu Qiuping Chen Zhao Lei Mingzhai Wang Hao Zhang Xiongjie Zhai Benhua Zhao Yanhua Su Yong Chen Xu-Sheng Zhang Jing-An Cui Roger Frutos Tianmu Chen | 2022 | Infectious Disease Modelling2022，7，2： | 1 |
| 20 | Construction of a high-density mutant population of Chinese cabbage facilitates the genetic dissection of agronomic traits显示文摘Chinese cabbage(Brassica rapa ssp.pekinensis)is an economically important vegetable crop throughout the world,especially in Asia.High-quality genome sequences are available for Chinese cabbage,but gene functional studies remain challenging.To promote functional genomic studies of Chinese cabbage,we generated an ethyl methane sulfonate(EMS)mutant population of~8000 M_(2) plants using the double haploid inbred line A03 as the parent.The genome of A03 was sequenced and used as a reference for high-throughput functional characterization of gene mutations at the whole-genome level.A total of 300 M_(2) to M_(5) EMS mutants were phenotypically screened and then sequenced,revealing 750629 SNPs and 46272 InDel mutations that cover 98.27%of all predicted genes in the A03 genome.A forward-genetics approach was successfully used to identify two genes with chloroplast-related functions that are responsible for the yellow leaf mutant trait.A reverse-genetics approach was also used to identify associations between mutations in five genes of the glucosinolate biosynthetic pathway and variations in glucosinolate content of the mutant plants.In addition,we built the Chinese cabbage EMS mutation database(CCEMD,www.bioinformaticslab.cn/EMSmutation/home)to increase the usability of this mutant population resource.In summary,we performed large-scale screening of a heading Chinese cabbage EMS mutant collection at the phenotypic and genotypic levels,which will facilitate gene mining of Chinese cabbage and might also be useful for the study of other Brassica crops. | Xiaoxue Sun Xing Li Yin Lu Shan Wang Xiaomeng Zhang Kang Zhang Xiangjie Su Mengyang Liu Daling Feng Shuangxia Luo Aixia Gu Yu Fu Xueping Chen Shuxin Xuan Yanhua Wang Donghui Xu Shumin Chen Wei Ma Shuxing Shen Feng Cheng Jianjun Zhao | 2022 | Molecular Plant2022，15，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员