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| 1 | Designing Thought,Technical Line and Some Theoretical Issues on Geospatial Digital Framework of China显示文摘Based on the developing tendency of present China’s basic GIS,this paper discusses the designing idea for scales of 1∶10 000,1∶50 000, 1∶250 000 and 1∶1 000 000 pyramid_like multi_layer and multi_resolution of the basic GIS.A technical line for the construction of basic GIS of the whole country and various provinces for sustainable development is put forward.And some important theoretical GIS issues touched by the technical process are discussed. | HU Peng HU Yuju YANG Chuanyong WU Yanlan HU Haiprofessor,School of Resource and Environment Science,Wuhan University,129 Luoyu Road,Wuhan 430079,China. | 2002 | Geo-Spatial Information Science2002，5，3： | 1 |
| 2 | MATHEMATICAL BASIS FOR LARGE SCALE GIS AND TERRESTRIAL DIGITAL PRODUCTS显示文摘The problem of spatial mathematical basis has been encountered by both large scale GIS and spatial digital products theoretically and practically.It is also a basic problem in the development of the whole geo_information science.After analyzing the status quo and the limitations of the space mathematical base of GIS,this paper points out definitely that the geodetic coordinate system is uniform,which can show the location of any point of the global exactly and uniquely in form of ( B,L,H ) and is the most proper reference system of large_scale GIS and Digital Earth.Moreover,this paper also puts forward a set of practical model of the standard 'map projection'.Finally,this paper introduces a DRG system based on this model. | HU Yuju HU Peng WU Yanlan YANG Chuanyong LI Guojian | 2001 | Geo-Spatial Information Science2001，4，3： | 0 |
| 3 | Massive and parallel 10 Tbit/s physical random bit generation with chaotic microcomb显示文摘Ultrafast physical random bit(PRB)generators and integrated schemes have proven to be valuable in a broad range of scientifc and technological applications.In this study,we experimentally demonstrated a PRB scheme with a chaotic microcomb using a chip-scale integrated resonator.A microcomb contained hundreds of chaotic channels,and each comb tooth functioned as an entropy source for the PRB.First,a 12 Gbits/s PRB signal was obtained for each tooth channel with proper post-processing and passed the NIST Special Publication 800-22 statistical tests.The chaotic microcomb covered a wavelength range from 1430 to 1675 nm with a free spectral range(FSR)of 100 GHz.Consequently,the combined random bit sequence could achieve an ultra-high rate of about 4 Tbits/s(12 Gbits/s×294=3.528 Tbits/s),with 294 teeth in the experimental microcomb.Additionally,denser microcombs were experimentally realized using an integrated resonator with 33.6 GHz FSR.A total of 805 chaotic comb teeth were observed and covered the wavelength range from 1430 to 1670 nm.In each tooth channel,12 Gbits/s random sequences was generated,which passed the NIST test.Consequently,the total rate of the PRB was approximately 10 Tbits/s(12 Gbits/s×805=9.66 Tbits/s).These results could ofer potential chip solutions of Pbits/s PRB with the features of low cost and a high degree of parallelism. | Yuqi Hu Qingsong Bai Xi Tang Wei Xiong Yilu Wu Xin Zhang Yanlan Xiao Runchang Du Leiji Liu Guangqiong Xia Zhengmao Wu Junbo Yang Heng Zhou Jiagui Wu | 2023 | Frontiers of Optoelectronics2023，16，3： | 0 |
| 4 | Mendelian randomization study to investigate the causal relationship between plasma homocysteine and chronic obstructive pulmonary disease显示文摘BACKGROUND:Several observational studies have shown an association between homocysteine(Hcy)levels and chronic obstructive pulmonary disease(COPD),but causal relationships are not clear.Our study aimed to explore the causal relationship between plasma Hcy and COPD by two-sample Mendelian randomization(MR).METHODS:A two-sample MR study was performed to infer the causal link.Genetically predicted plasma Hcy was selected as an instrumental variable(Ⅳ)from published genome-wide association study(GWAS)meta-analyses.COPD with different etiologies was extracted as outcome variables from other GWAS meta-analyses.The main MR analysis was performed using the inversevariance weighted(IVW)method.Additional analyses were further performed using Cochran’s Q-test and MR-Egger regression to evaluate the heterogeneity or horizontal pleiotropy of our findings.RESULTS:MR analysis showed no significant association between plasma Hcy and COPD.The results of the groups were consistent with the sensitivity analysis and repeated analysis,without heterogeneity or horizontal pleiotropy.The IVW results showed COPD hospital admissions(odds ratio[OR]1.06,95%confidence interval[CI]0.91-1.24,P=0.42),asthma/COPD(OR 0.97,95%CI0.89-1.06,P=0.55),COPD-related chronic infection(OR 1.50,95%CI 0.57-3.99,P=0.41),COPDI asthma/interstitial lung disease(ILD)-related pneumonia or pneumonia-derived septicemia(OR 0.93,95%CI 0.86-1.02,P=0.13),and COPD-related respiratory insufficiency(OR 1.00,95%CI 0.7-1.44,P=0.99).CONCLUSION:There is no direct causal relationship between plasma Hcy and COPD in our study.As Hcy is known to have deleterious effects on endothelial function and vascular homeostasis,further studies are needed to investigate whether additional factors mediate the association between Hcy and COPD. | Yanlan Hu Ping Tan Juntao Wang Jun Zeng Quan Li Shijiao Yan Wenjie Hao Lanfen He Xingyue Song Caihong Zhang Chuanzhu Lyu | 2023 | World Journal of Emergency Medicine2023，14，5： | 0 |
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