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| 1 | Nanopore-based Fourth-generation DNA Sequencing Technology显示文摘Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have the potential to quickly and reliably sequence the entire human genome for less than $1000, and possibly for even less than $100. The single-molecule techniques used by this technology allow us to further study the interaction between DNA and protein, as well as between protein and protein.Nanopore analysis opens a new door to molecular biology investigation at the single-molecule scale.In this article, we have reviewed academic achievements in nanopore technology from the past as well as the latest advances, including both biological and solid-state nanopores, and discussed their recent and potential applications. | Yanxiao Feng Yuechuan Zhang Cuifeng Ying Deqiang Wang Chunlei Du | 2015 | Genomics, Proteomics & Bioinformatics2015，13，1： | 11 |
| 2 | Corrigendum to ‘Nanopore-based Fourth-generation DNA Sequencing Technology' [GPB 144(2015)–GPB 13/1(4–16)]显示文摘The authors regret that there were typos in the online version of Figure 4 published in Issue 1,2015.In the figure legend boxes of panels F and G,‘‘Ni’’should be corrected to‘‘N’’for the labeling of the green curves.The figure in the printed version has been corrected.The correct Figure 4 is shown below.The authors would like to apologize for any inconvenience caused. | Yanxiao Feng Yuechuan Zhang Cuifeng Ying Deqiang Wang Chunlei Du | 2015 | Genomics, Proteomics & Bioinformatics2015，13，3： | 9 |
| 3 | Creation of aromatic maize by CRISPR/Cas显示文摘Aroma is an important quality parameter for breeding in rice(Oryza sativa).For example,the aromatic rice varieties basmati and jasmine rice,with a popcorn-like scent,are popular worldwide and routinely command a price premium.2-acetyl-1-pyrroline(2AP)is a key flavor compound among over 200 volatiles identified in fragrant rice.A naturally fragrant germplasm exists in multiple plant species besides rice,which all exhibit lower activity of BETAINE ALDEHYDE DEHYDROGENASE 2(BADH2).However,no equivalent aromatic germplasm has been described in maize(Zea mays).Here,we characterized the two maize BADH2 homologs,ZmBADH2a and ZmBADH2b.We generated zmbadh2a and zmbadh2b single mutants and the zmbadh2a-zmbadh2b double mutant by CRISPR/Cas in four inbred lines.A popcorn-like scent was only noticeable in seeds from the double mutant,but not from either single mutant or in wild type.In agreement,we only detected 2AP in fresh kernels and dried mature seeds from the double mutant,which accumulated between 0.028 and 0.723 mg/kg 2AP.These results suggest that ZmBADH2a and ZmBADH2b redundantly participate in 2AP biosynthesis in maize,and represent the creation of the world's first aromatic maize by simultaneous genome editing of the two BADH2 genes. | Yanxiao Wang Xiaoqin Liu Xiuxiu Zheng Wenxia Wang Xunqing Yin Haifeng Liu Changle Ma Xiaomu Niu Jian-Kang Zhu Fei Wang | 2021 | Journal of Integrative Plant Biology2021，63，9： | 3 |
| 4 | The diversity of adult lung epithelial stem cells and their niche in homeostasis and regeneration显示文摘The adult lung,a workhorse for gas exchange,is continually subjected to a barrage of assaults from the inhaled particles and pathogens.Hence,homeostatic maintenance is of paramount importance.Epithelial stem cells interact with their particular niche in the adult lung to orchestrate both natural tissue rejuvenation and robust post-injury regeneration.Advances in single-cell sequencing,lineage tracing,and living tissue imaging have deepened our understanding about stem cell heterogeneities,transition states,and specific cell lineage markers.In this review,we provided an overview of the known stem/progenitor cells and their subpopulations in different regions of the adult lung,and explored the regulatory networks in stem cells and their respective niche which collectively coordinated stem cell quiescence and regeneration states.We finally discussed relationships between dysregulated stem cell function and lung disease. | Yanxiao Wang Nan Tang | 2021 | Science China(Life Sciences)2021，64，12： | 3 |
| 5 | Simultaneous N-intercalation and N-doping of epitaxial graphene on 6H-SiC(0001) through thermal reactions with ammonia显示文摘6H-SiC (0001 ) 上的取向附生的 graphene overlayers 的表面 functionalization 在 NH3 通过热反应被尝试了。X 光检查光电子光谱学和 N 的重要数量在对待 NH3 的 graphene 是在场的微区域的低精力电子衍射结果表演出现,它导致强壮的乐队弯曲在原文如此从底层象 graphene overlayers 的去耦一样出现。表面 N 种类的多数能被在真空退火直到 850 移开 ? | Zhou-jun Wang Mingming Wei Li Jin Yanxiao Ning Liang Yu Qiang Fu Xinhe Bao | 2013 | Nano Research2013，6，6： | 3 |
| 6 | Student Performance Prediction Based on Behavior Process Similarity显示文摘Student performance prediction plays an important role in improving education quality.Noticing that students'exercise-answering processes exhibit different characteristics according to their different performance levels,this paper aims to mine the performance-related information from students'exercising logs and to explore the possibility of predicting students'performance using such process-characteristic information.A formal model of student-shared exercising processes and its discovery method from students'exercising logs are presented.Several similarity measures between students'individual exercising behavior and student-shared exercising processes are presented.A prediction method of students'performance level considering these similarity measures is explored based on classification algorithms.An experiment on real-life exercise-answering event logs shows the effectiveness of the proposed prediction method. | BAO Yunxia LU Faming WANG Yanxiao ZENG Qingtian LIU Cong | 2020 | Chinese Journal of Electronics2020，29，6： | 3 |
| 7 | Defining reference genes for quantitative real-time PCR analysis of anther development in rice显示文摘量的即时聚合酶链反应(qPCR ) 是为基因 expressionanalysis 的最精确、广泛地使用的方法之一。然而,为正规化的引用基因的选择为 genomics 的基因 expression.As 开发的精确 quantification 是批评的,采矿大规模数据集象 microarray 和定序 RNA 那样数据成为新引用基因的新 approachfor 利用。在这研究,我们分析了包含不同纸巾和米饭花药和花粉的发展中的阶段的米饭花药和 167 microarraydatasets 的定序 RNA 数据集。我们选择了 5 参考基因,包括的 ACT1, eEF-1, GAPDH, Exp2,和 CCDC72 在以前的研究使用了的 12 候选人基因 andother,并且在八纸巾和花药 inrice 变化 9311 的不同发展阶段和 Yuetai 计算了他们的表达式。UPF3, eIF4A-3, GAPDH,和 PPP6 在米饭为花药开发的 qPCR 分析作为最合适的参考基因被识别。新候选人 referencegenes 比传统地使用的参考基因显示出更多的稳定的表示。这些结果在米饭花药为研究提供一套可靠 referencegenes 发展过程。 | Yanxiao Ji Ping Tu Kun Wang Feng Gao Weilong Yang Yingguo Zhu Shaoqing Li | 2014 | Acta Biochimica et Biophysica Sinica2014，46，4： | 2 |
| 8 | Controlled growth of uniform two-dimensional ZnO overlayers on Au(111)and surface hydroxylation显示文摘Ultrathin ZnO nano structures prese nt in teresti ng two-dimensi on al(2D)graphene-like structure in contrast to wurtzite structure in bulk ZnO.Growth on Au(111)has been regarded as a well-established route to the 2D ZnO layers while controlled growth of uniform ZnO nano structures remains as a challe nge.Here,reactive deposition of Zn in O3 and NO2 was employed,which is investigated by sea nning tunneling microscopy and X-ray photoelectr on spectroscopy(XPS).We dem on strate that uniform ZnO mono layer nanoislands and films can be obtained on Au(111)using O3 and uniform ZnO bilayer nanoislands and films form on Au(111)using NO2,respectively.Formation of atomic oxyge n overlayers on Au(111)via exposure to O3 is critical to the formatio n of uniform ZnO mono layer nano structures atop.Near ambient pressure XPS studies revealed that n early full hydroxy lati on occurs on mono layer ZnO structures upon exposure to near ambient pressure water vapor or atomic hydrogen species,while partial surface hydroxylation happens on bilayer ZnO under the same gaseous exposure conditions. | Hao Wu Qiang Fu Yifan Li Yi Cui Rui Wang Nan Su Le Lin Aiyi Dong Yanxiao Ning Fan Yang Xinhe Bao | 2019 | Nano Research2019，12，9： | 1 |
| 9 | Fe-Nx Sites enriched microporous carbon nanoflower planted with tangled bamboo-like carbon nanotube as a strong polysulfides anchor for lithium-sulfur batteries显示文摘Serious shuttle effect and sluggish conversion kinetics of lithium polysulfides(LiPSs)have a massive impact on obstructing the practical application of lithium-sulfur(Li-S)batteries.To address such issues,Fe-Nx sites enriched microporous nanoflowers planted with tangled bamboo-like carbon nanotubes(Fe-Nx-C/Fe_(3)C-CNTs NFs)are found to be effective catalytic mediators with strong anchoring capabilities for LiPSs.The bamboo-like carbon nanotubes catalyzed by Fe_(3)C/Fe entangled each other to form a conductive network,which encloses a flowerlike microporous carbon core with embedded well-dispersed Fe-Nx active sites.As expected,electrons smoothly transfer along the dense conductive bamboo-like carbon network while the flower-like carbon core consisting of micropores induces the homogeneous distribution of tiny sulfur and favors the lithium ions migration with all directions.Meanwhile,Fe-Nx sites strongly trap long-chain LiPSs with chemical anchoring,and catalyze the redox conversion of LiPSs.Due to the aforementioned synergistic effects,the S@Fe-Nx-C/Fe_(3)C-CNTs NFs cathode exhibited a remarkable specific capacity(635 mAh g_(s)^(-1))at 3 C and a favorable capacity decay with 0.04%per cycle even after 400 cycles at 1 C. | Hongtai Li Yanxiao Chen Quan Jin Wei Xiang Benhe Zhong Xiaodong Guo Bao Wang | 2021 | Green Energy & Environment2021，6，4： | 1 |
| 10 | Adsorption properties of oxidized carboxymethyl starch and cross -linked carboxymethyl starch for calcium ion显示文摘 | Chen Yanxiao Wang Gongying | 2006 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2006，289，13： | 1 |
| 11 | Kinetics and adsorption behavior of carboxymethyl starch on a-alumina in aqueous medium显示文摘 | Yanxiao Chen Shaoying Liu Gongying Wang | 2006 | Journal of Colloid and Interface Science2006，303，2： | 1 |
| 12 | Adsorption properties of oxidized carboxymethyl starch and cross-linked carboxymethyl starch for calcium ion显示文摘 | Chen Yanxiao Wang Gongying | 2006 | Colloids and Surface A2006，289，： | 1 |
| 13 | Adsorption properties of oxidized carboxymethyl starch and cross-linked carboxymethyl starch for calcium ion 显示文摘 | Chen Yanxiao Wang Gongying | 2006 | Colloids and Surfaces A : Physicochem Eng Aspects2006，289，： | 1 |
| 14 | A kinetic investigation of cationic starch adsorption and flocculation in kaolin suspension显示文摘 | Yanxiao Chen Shaoying Liua Gongying Wang | 2007 | Chemical Engineering Journal2007，133，13： | 1 |
| 15 | Electrolyte-dependent formation of solid electrolyte interphase and ion intercalation revealed by in situ surface characterizations显示文摘The formation of solid electrolyte interphase(SEI) and ion intercalation are two key processes in rechargeable batteries, which need to be explored under dynamic operating conditions. In this work, both planar and sandwich model lithium batteries consisting of Li metal | ionic liquid electrolyte | graphite electrode have been constructed and investigated by a series of in situ surface analysis platforms including atomic force microscopy, Raman and X-ray photoelectron spectroscopy. It is found that the choice of electrolyte, including the concentration and contents, has a profound effect on the SEI formation and evolution, and the subsequent ion intercalation. A smooth and compact SEI is preferably produced in highconcentration electrolytes, with FSI^(-) salt superior to TFSI^(-) salt, facilitating the lithiation/delithiation to achieve high capacity and excellent cycle stability, while suppressing the co-intercalation of electrolyte solvent ions. The innovative research scenario of well-defined model batteries in combination with multiple genuinely in situ surface analysis methods presented herein leads to insightful results, which provide valuable strategies for the rational design and optimization of practical batteries, and energy storage devices in general. | Shiwen Li Chao Wang Caixia Meng Yanxiao Ning Guohui Zhang Qiang Fu | 2022 | Journal of Energy Chemistry2022，31，4： | 1 |
| 16 | Effects of Copper-based Nutritional Foliar Fertilizers on Photosynthetic Characteristics,Yield and Disease Control Efficiency of Cotton显示文摘[Objectives] The effects of copper-based nutrient foliar fertilizer on photosynthetic characteristics,yield,accumulation and distribution of trace elements in various organs,disease prevention effect and soil enzyme activity were studied,so as to provide a theoretical basis for the application of foliar fertilizers in cotton production. [Methods]Through two years of field experiments,six treatments were set in total,namely spraying water( CK),traditional Bordeaux mixture( BDM),Kocide 2000( KCD),copper-based nutrient foliar fertilizer( CF),iron-copper-based nutrient foliar fertilizer( CFFe),and zinc-boron-copper-based nutrient foliar fertilizer( CFZnB). Randomized block arrangement was adopted. Chlorophyll content in leaves was measured at each growth stage of the cotton. Photosynthetic characteristics of leaves were measured at the peak bolling stage. Plants were sampled at initial boll opening stage. The whole plant was divided into root,stem,leaf and cotton boll parts,in which the total copper,total zinc,total iron contents and accumulations were determined. Soil samples were collected from each plot,followed by the determination of soil enzyme activity. Disease index was investigated at bud,flowering and boll-forming and boll opening stage. [Results]( 1) Spraying CFFe,CFZnB,CF and KCD could significantly improve chlorophyll content of cotton leaves,and the CFFe treatment had the highest increase up to13. 30%,followed by the CFZnB treatment,which was 11. 40% higher than the CK; and photosynthetic rate,stomata conductance and transpiration rate could be improved significantly,and the CFFe treatment showed the highest photosynthetic rate,which increased by 26. 35% compared with the CK,followed by the CFZnB treatment,which increased by 17. 96% compared with CK; and intercellular CO2 concentration was significantly reduced.( 2) Spraying BDM,KCD,CF,CFFe and CFZnB can significantly increase total copper content and accumulation in various cotton organs( except the total copper content in the stem part of the CFZnB treatment; the CFZnB and CFFe treatments can significantly increase total zinc content and accumulation in various cotton organs; and spraying CFFe,CFZnB and CF can significantly increase total iron content and accumulation in various cotton organs( except the total iron content in the stem part of the CF treatment).( 3)Spraying CFFe,CFZnB,CF,KCD and BDM greatly reduced the disease index at flowering and boll-forming and boll opening stages.( 4) The CFZnB and CFFe treatments had the highest soil urease activity,which was 7. 14% higher than that of the CK,but the difference from the CK was not significant; the catalase activity of each treatment was significantly higher than that of the BDM treatment; and the sucrase activity of each treatment was significantly higher than that of the CK.( 5) Spraying CFFe,CFZnB,CF and KCD significantly improved lint yield of cotton,and the CFZnB treatment showed the highest yield increase up to 12. 34%,followed by the CFFe treatment,with an increase in the range of 8. 77%-10. 20%. [Conclusions]Copper-based nutrient foliar fertilizers have dual functions of disease control and prevention and plant nutrition and health care,and not only can significantly increase cotton yield,but also has certain disease prevention effect.It is recommended to use copper-based nutrient foliar fertilizers. | Qiang MA Wei WANG Hongjie LI Xiangjun WANG Zishuang LI Tongkai ZHAO Xianhe ZHENG Yanxiao TAN | 2019 | Agricultural Biotechnology2019，8，1： | 1 |
| 17 | Kinetics and adsorption behavior of carboxymethyl starch on α -alumina in aqueous medium显示文摘 | Yanxiao Chen Shaoying Liu Gongying Wang | 2006 | Journal of Colloid And Interface Science2006，，2： | 1 |
| 18 | A kinetic investigation of cationic starch adsorption and flocculation in kaolin suspension 显示文摘 | Yanxiao Chen Shaoying Liua Gongying Wang | 2007 | Chemical Engineering Journal2007，133，13： | 1 |
| 19 | Synthesis and Physi- cochemical Properties of Graft Copolymer of Corn Starch and Acrylam- ide 显示文摘 | Chen Yanxiao Liu Shaoying Wang Gongying | 2006 | Polymer Composites2006，27，6： | 1 |
| 20 | Crystal-plane-dependent redox reaction on Cu surfaces显示文摘The dynamic redox process of surface oxide layers on metal surfaces is of great significance for understanding the active phase in catalytic reactions.We studied the formation of surface oxide layers on Cu(111)and Cu(110)in O2,as well as the subsequent reduction by CO using in situ scanning tunneling microscopy(STM)and X-ray photoelectron spectroscopy(XPS).By monitoring and comparing the oxidation process of Cu(111)and Cu(110)surfaces,we found a crystal-plane-dependent reaction mechanism,which also applies to the reduction of surface oxide layers on Cu surfaces.We found XPS Cu spectra cannot be used to identify the various surface oxide layer on Cu surfaces,suggesting their presence in catalytic reactions might have been overlooked.The combination of STM and XPS studies are thus advantageous in identifying surface oxide structures and pinpointing the active phases in the redox process,which paves the way for engineering the catalyst and reaction environment for optimized catalytic performances. | Yangsheng Li Hao Chen Weijia Wang Wugen Huang Yanxiao Ning Qingfei Liu Yi Cui Yong Han Zhi Liu Fan Yang Xinhe Bao | 2020 | Nano Research2020，13，6： | 0 |
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