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| 1 | Single-incision laparoscopic cholecystectomy:Single institution experience and literature review显示文摘Single-incision laparoscopic surgery is a rapidly evolving field as a bridge between traditional laparoscopic surgery and natural orifice transluminal endoscopic surgery.We report one of the initial clinical experiences in Japan with this new technique.Four cases of gallbladder diseases were selected for this new technique.A single curved intra-umbilical 25-mm incision was made by pulling out the umbilicus.A 12-mm trocar was placed through an open approach,and the abdominal cavity was explored with a 10-mm semiflexible laparoscope.Two 5-mm ports were inserted laterally from the laparoscope port.A 2-mm mini-loop retractor was inserted to retract the fundus of the gallbladder.Dissection was performed using an electric cautery hook and an Endograsper roticulator.There were two women and two men with a mean age of 50.5 years(range:40-61 years).All procedures were completed successfully without any perioperative complications.In all cases,there was no need to extend the skin incision.Average operative time was 88.8 min.Postoperative follow-up didnot reveal any umbili-cal wound complication.Single-incision laparoscopic cholecystectomy is feasible and a promising alternative method as scarless abdominal surgery for the treatment of some patients with gallbladder disease. | Yasumitsu Hirano Toru Watanabe Tsuneyuki Uchida Shuhei Yoshida Kanae Tawaraya Hideaki Kato Osamu Hosokawa | 2010 | World Journal of Gastroenterology2010，16，2： | 23 |
| 2 | Scoring system for prediction of metastatic spine tumor prognosis显示文摘Assessing the prognosis before treatment for metastatic spine tumor is extremely important in therapy selection.Therefore,we review some prognostic scoring systems and their outcomes.Articles with combinations of two keywords among'metastatic spine tumor'and'prognosis','score','scoring system','predicting',or'life expectancy'were searched for in Pub Med.As a result,236 articles were extracted.Those referring to representative scoring systems about predicting the survival of patients with metastatic spine tumors were used.The significance and limits of these scoring systems,and the future perspectives were described.Tokuhashi score,Tomita score,Baur score,Linden score,Rades score,and Katagiri score were introduced.They are all scoring systems prepared by combining factors that affect prognosis.The primary site of cancer and visceral metastasis were common factors in all of these scoring systems.Other factors selected to influence the prognosis varied.They were useful to roughly predict thesurvival period,such as,'more than one year or not'or'more than six months or not'.In particular,they were utilized for decision-making about operative indications and avoidance of excessive medical treatment.Because the function depended on the survival period in the patients with metastatic spine tumor,it was also utilized in assessing functional prognosis.However,no scoring system had more than 90%consistency between the predicted and actual survival periods.Future perspectives should adopt more oncological viewpoints with adjustment of the process of treatment for metastatic spine tumor. | Yasuaki Tokuhashi Hiroshi Uei Masashi Oshima Yasumitsu Ajiro | 2014 | World Journal of Orthopedics2014，5，3： | 19 |
| 3 | Immunological Effects of Silica and Asbestos显示文摘Silicosis patients(SILs) and patients who have been exposed to asbestos develop not only respiratory diseases but also certain immunological disorders. In particular,SIL sometimes complicates autoimmune diseases such as systemic scleroderma,rheumatoid arthritis(known as Caplan syndrome) ,and systemic lupus erythematoses. In addition,malignant complications such as lung cancer and malignant mesothelioma often occurr in patients exposed to asbestos,and may be involved in the reduction of tumor immunity. Although silica-induced disorders of autoimmunity have been explained as adjuvant-type effects of silica,more precise analyses are needed and should reflect the recent progress in immunomolecular findings. A brief summary of our investigations related to the immunological effects of silica/asbestos is presented. Recent advances in immunomolecular studies led to detailed analyses of the immunological effects of asbestos and silica. Both affect immuno-competent cells and these effects may be associated with the pathophysiological development of complications in silicosis and asbestos-exposed patients such as the occurrence of autoimmune disorders and malignant tumors,respectively. In addition,immunological analyses may lead to the development of new clinical tools for the modification of the pathophysiological aspects of diseases such as the regulation of autoimmunity or tumor immunity using cell-mediated therapies,various cytokines,and molecule-targeting therapies. In particular,as the incidence of asbestos-related malignancies is increasing and such malignancies have been a medical and social problem since the summer of 2005 in Japan,efforts should be focused on developing a cure for these diseases to eliminate nationwide anxiety. | Takemi Otsuki Megumi Maeda Shuko Murakami Hiroaki Hayashi Yoshie Miura Masayasu Kusaka Takashi Nakano Kazuya Fukuoka Takumi Kishimoto Fuminori Hyodoh Ayako Ueki Yasumitsu Nishimura | 2007 | Cellular & Molecular Immunology2007，4，4： | 9 |
| 4 | Single-incision laparoscopic surgery for colorectal cancer显示文摘AIM: To determine the effect of single-incision laparoscopic colectomy(SILC) for colorectal cancer on short-term clinical and oncological outcomes by comparison with multiport conventional laparoscopic colectomy(CLC).METHODS: A systematic review was performed using MEDLINE for the time period of 2008 to December 2014 to retrieve all relevant literature. The search terms were 'laparoscopy', 'single incision', 'single port', 'single site', 'SILS', 'LESS' and 'colorectal cancer'. Publications were included if they were randomized controlled trials, case-matched controlled studies, or comparative studies, in which patients underwent single-incision(SILS or LESS) laparoscopic colorectal surgery. Studies were excluded if they were non-comparative, or not including surgery involving the colon or rectum. A total of 15 studies with 589 patients who underwent SILC for colorectal cancer were selected.RESULTS: No significant differences between the groups were noted in terms of mortality or morbidity. The benefit of the SILC approach included reduction in conversion rate to laparotomy, but there were no significant differences in other short-term clinical outcomes between the groups. Satisfactory oncological surgical quality was also demonstrated for SILC for the treatment of colorectal cancer with a similar average lymph node harvest and proximal and distal resection margin length as multiport CLC.CONCLUSION: SILC can be performed safely with similar short-term clinical and oncological outcomes as multiport CLC. | yasumitsu hirano masakazu hattori kenji douden yasuhiro ishiyama yasuo hashizume | 2016 | World Journal of Gastrointestinal Surgery2016，8，1： | 9 |
| 5 | 上海地区复合式太阳能-地源热泵季节性蓄热供热系统的模拟研究显示文摘本文以上海地区复合式太阳能-地源热泵季节性蓄热供热系统为研究对象,在蓄热模式和供热模式这两种运行模式下,利用TRNSYS软件建立系统模型,研究该系统在一个完整的蓄热季和供热季下,土壤温变特性、系统能量损失和系统热效率随时间的变化规律。结果表明:上海地区复合式太阳能-地源热泵季节性蓄热供热系统在蓄热季可实现土壤蓄热温度45.7℃,蓄热季土壤蓄热率为42.70%,蓄热效果良好。同时在供热季实现高效的热量供给,供热季太阳能保证率为0.3。系统全年性能系数(Coefficient of Performance,COP)为3.76,具有良好的节能效果。 | 李好 李勇 Shunkei SUZUKI Yasumitsu NOMURA 王如竹 | 2020 | 制冷技术2020，40，1： | 7 |
| 6 | Combined choriocarcinoma, neuroendocrine cell carcinoma and tubular adenocarcinoma in the stomach显示文摘We described a patient with adenocarcinoma of the stomach combined with choriocarcinoma and neuroendocrine cell carcinoma. An 85-year-old man visited our hospital because of appetite loss. Gastric fiberscopy revealed a large tumor occupying the cardial region and anterior wall of the gastric body. The patient underwent total gastrectomy with lymphnode dissection and partial resection of the liver. Choriocarcinoma, small cell carcinoma and tubular adenocarcinoma existed in the gastric tumor. The choriocarcinomatous foci contained cells positive for beta-subunit of human chorionic gonadotropin (B-hCG) and human placental lactogen mainly in syncytiotrophoblastic cells. The small cell carcinomatous foci contained cells positive for synaptophysin, neuron-specific enolase (NSE), and chromogranin A. The prognosis for gastric adenocarcinoma with choriocarcinoma and neuroendocrine cell carcinoma is exceedingly poor. This patient died about 2 mo after the first complaint from hepatic failure. This is the first reported case of gastric cancer with these three pathological features. | Yasumitsu Hirano Takuo Hara Hiroshi Nozawa Kaeko Oyama Naohiro Ohta Kenji Omura Go Watanabe Hideki Niwa | 2008 | World Journal of Gastroenterology2008，14，20： | 6 |
| 7 | Length-Sorted Semiconducting Carbon Nanotubes for High-Mobility Thin Film Transistors显示文摘我们为 solution-processable 为碳 nanotubes 的化学纯化开发了一个过程有高活动性的薄电影的晶体管(TFT ) 。简单落下涂层制作的净化的碳 nanotubes 的电影象 164 cm2V1s1, 0.78 Sm1 的规范的跨导,和开/关电流一样高显示出搬运人活动性 106 的比率。如此的高效要求测微计长、高度净化的半导体的围单人赛的碳 nanotubes (SWCNT ) 的暂停的准备。我们的纯化过程包括长度并且用与表面活化剂的混合物再循环胶化过滤的 SWCNT 的电子类型的选择套住。结果提供一个重要里程碑向与 roll-to-roll 和墨水喷气设备制造打印了高速度、大区域的电子学。 | Yasumitsu Miyata Kazunari Shiozawa Yuki Asada Yutaka Ohno Ryo Kitaura Takashi Mizutani Hisanori Shinohara | 2011 | Nano Research2011，4，10： | 5 |
| 8 | Decrease in Serum Amyloid a Protein Levels Following Three-month Stays in Negatively Charged Particle-dominant Indoor Air Conditions显示文摘Objective The changes in serum adipokines and cytokines related to oxidative stress were examined during 3 months ‘Off to On' and ‘On to Off' periods using negatively charged particle-dominant indoor air conditions(NCPDIAC).Methods Seven volunteers participated in the study,which included ‘OFF to 3 months ON' periods(ON trials) for a total of 16 times,and ‘ON to 3 months OFF'(OFF trials) periods for a total of 13 times.Results With the exception of one case,serum amyloid A(SAA) levels decreased significantly during the ON trials.Conclusion Considering that SAA is an acute phase reactive protein such as C reactive protein(CRP),this observed decrease might indicate the prevention of cardiovascular and atherosclerotic changes,since an increase in high-sensitive CRP is associated with the subsequent detection of these events. | Suni Lee Shoko Yamamoto Yasumitsu Nishimura Hidenori Matsuzaki Kei Yoshitome Tamayo Hatayama Miho Ikeda YU Min Nagisa Sada Naoko Kumagai-Takei Takemi Otsuki | 2018 | Biomedical and Environmental Sciences2018，31，5： | 5 |
| 9 | Bandgap-tunable lateral and vertical heterostructures based on monolayer Mo1-xWxS2 alloys显示文摘有特定的 bandgaps 的二维的半导体的 heterostructures 的制造是认识到这些材料的完整的潜力在的一条重要途径电子并且 optoelectronic 设备。几个组最近基于象 WSe 2, MoSe 2, WS 2, 和瞬间 2 那样的典型半导体的转变金属 dichalcogenides (TMDC ) 的单层报导了侧面、垂直的 heterostructures 的直接生长。这里,我们基于 bandgap 悦耳的瞬间 1-x W x 由 WO 3 和哞 3 的有图案的薄电影的 sulfurization 的 S 2 合金单层。这些有图案的电影能够在水晶生长阶段期间由转变金属的散开产生许多集中坡度。在高温度下面,这导致瞬间 1-x W x 有各种各样的作文和 bandgaps 的 S 2 合金,在底层上取决于晶体的位置。这些合金的 Heterostructures 在低温度的生长期间在一个单个领域以内在 W/Mo 的比率通过逐步的变化被获得。单层瞬间 1-x W x S 2 合金,经常甚至在轻轻的条件下面降级,被涂层完成有另外的单层的合金。现在的调查结果表明学习并且优化基于 TMDC 的 heterostructures 的光、电的性质在未来设备应用允许材料的使用的一个有效工具。 | Yu Kobayashi Shohei Mori Yutaka Maniwa Yasumitsu Miyata | 2015 | Nano Research2015，8，10： | 3 |
| 10 | Tissue Oxygen Saturation during Colorectal Surgery Measured by Near-infrared Spectroscopy: Pilot Study to Predict Anastomotic Complications显示文摘 | Yasumitsu Hirano MD PhD Kenji Omura MD PhD Yasuhiko Tatsuzawa MD PhD Junzo Shimizu MD PhD Yukimitsu Kawaura MD PhD Go Watanabe MD PhD | 2006 | World Journal of Surgery2006，，3： | 2 |
| 11 | Speciation of selenium in selenium-enriched shiitake mushroom, Lentinula edodes 显示文摘 | Yasumitsu Ogra AE Kazuya Ishiwata Jorge Ruiz Encinar | 2004 | Anal Bioanal Chem2004，379，： | 1 |
| 12 | Speciation of Arsenic in Body Fluids显示文摘 | Kazuo T Suzuki Badal K Mandal Yasumitsu Ogra | 2002 | Talanta2002，58，： | 1 |
| 13 | Preparation of activated carbon moldings from the mixture of the waste newspaper and isolated lignins:mechanical strength of thin sheet and adsorption property显示文摘 | Yasumitsu Uraki Satoshi Kubo Yoshihiro | 2002 | Journal of Wood Science2002，48，： | 1 |
| 14 | Surgical results for small cell lung cancer based on the new TNM staging system显示文摘 | Inoue M Miyoshi S Yasumitsu T | | 0，，05： | 1 |
| 15 | Comparison Between Endoscopic Macroscopic Classification and F-18 FDG PET Findings in Gastric Mucosa–Associated Lymphoid Tissue Lymphoma Patients显示文摘 | Yasumitsu Hirose Hayato Kaida Masatoshi Ishibashi Jun Uozumi Shunji Arikawa Seiji Kurata Naofumi Hayabuchi Keita Nakahara Koichi Ohshima | 2012 | Clinical Nuclear Medicine2012，，2： | 1 |
| 16 | Outcome of Treatment for Spinal Metastases Using Scoring System for Preoperative Evaluation of Prognosis显示文摘 | Yasuaki Tokuhashi Yasumitsu Ajiro Natsuki Umezawa | 2009 | Spine2009，，1： | 1 |
| 17 | Bacterial cellulose production using monosaccharides derived from hemicelluloses in water-soluble fraction of waste liquor from atmospheric acetic acid pulping显示文摘 | Uraki Yasumitsu Morito Masaki Kishimoto Takao | 2002 | Holzforschung2002，56，4： | 1 |
| 18 | Cleaning efficacy and dentin micro-hardness after root canal irrigation with a strong acid electrolytic water显示文摘 | Yu Q Yasumitsu A Satoshi K | 2006 | Journal of Endodontics2006，32，11： | 1 |
| 19 | Trypsin stimulates integrin alpha5 betal - dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase- activated receptor - 2 显示文摘 | Miyata S Koshikawa N Yasumitsu H | 2000 | J Biol Chem2000，275，： | 1 |
| 20 | Preparation of activated carbon fibers with large specific surface area from softwood acid lignin显示文摘 | Yasumitsu Uraki Akira Nakatani Satoshi Kubo | 2001 | Journal of Wood Science2001，47，： | 1 |
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