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30篇 您的检索式:作者名="Yixin Qian"
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1Photocatalytic remediation of ionic pollutant显示文摘Recently, the photocatalysts have attracted lots of attention and efforts due to their great potential for environmental remediation application. Toxic ions in water are an increasing environmental pollutant with the fast development. Numerous researches have been made to develop photocatalysts to treat ionic pollutants under the illumination of ultraviolet light and visible light. Here,photocatalytic remediation of toxic ionic pollutants has been reviewed. This review summarized and discussed various photocatalysts including Ti O2, modified Ti O2,metal oxides, metalsulfides, and nitrides and their recent progress in removing ionic pollutants such as heavy metal ion. The latest achievements and their future prospects of photocatalytic remediation of ion pollutant have also been reviewed.Dongting Yue Xufang Qian Yixin Zhao 2015Science Bulletin2015,60,21:8
2Dynamic tensile behaviour and crack propagation of coal under coupled static-dynamic loading显示文摘The fracture behaviour and crack propagation features of coal under coupled static-dynamic loading conditions are important when evaluating the dynamic failure of coal.In this study,coupled static-dynamic loading tests are conducted on Brazilian disc(BD)coal specimens using a modified split Hopkinson pressure bar(SHPB).The effects of the static axial pre-stress and loading rate on the dynamic tensile strength and crack propagation characteristics of BD coal specimens are studied.The average dynamic indirect tensile strength of coal specimens increases first and then decreases with the static axial pre-stress increasing.When no static axial pre-stress is applied,or the static axial pre-stress is 30%of the static tensile strength,the dynamic indirect tensile strength of coal specimens shows an increase trend as the loading rate increases.When the static axial pre-stress is 60%of the static tensile strength,the dynamic indirect tensile strength shows a fluctuant trend as the loading rate increases.According to the crack propagation process of coal specimens recorded by high-speed camera,the impact velocity influences the mode of crack propagation,while the static axial pre-stress influences the direction of crack propagation.The failure of coal specimens is a coupled tensile-shear failure under high impact velocity.When there is no static axial pre-stress,tensile cracks occur in the vertical loading direction.When the static axial pre-stress is applied,the number of cracks perpendicular to the loading direction decreases,and more cracks occur in the parallel loading direction.Xianjie Hao Weisheng Du Yixin Zhao Zhuowen Sun Qian Zhang Shaohua Wang Haiqing Qiao 2020International Journal of Mining Science and Technology2020,30,5:8
3Advances and prospects of PVDF based polymer electrolytes显示文摘Exploring highly foldable batteries with no safety hazard is a crucial task for the realization of portable,wearable,and implantable electric devices.Given these concerns,developing solid-state batteries is one of the most promising routes to achieve this aspiration.Because of the excellent flexibility and processability,polyvinylidene fluoride(PVDF) based electrolytes possess great potential to pack high energy density flexible batteries,however,suffers the various intrinsic shortcomings such as inferior ionic conductivity,a high degree of crystallinity,and lack of reactive groups.Clearing the progress of the present state and concluding the specific challenges faced by PVDF based electrolytes will help to develop PVDF based polymer batteries.In this review,we summarize the recent progress of gel polymer electrolytes and all solid polymer electrolytes based on PVDF.The ion transport mechanisms and preparation methods of PVDF based electrolytes are briefly introduced.Meanwhile,the current design principle and properties of electrolytes are highlighted and systematically discussed.Some peculiar modified strategies performed in lithium-sulfur batteries and lithium-oxygen batteries are also included.Finally,this review describes the challenges and prospects of some solid-state electrolytes to provide strategies for manufacturing high-performance PVDF electrolytes aimed at practical application with flexible requirements.Yixin Wu Yu Li Yang Wang Qian Liu Qingguo Chen Minghua Chen 2022Journal of Energy Chemistry2022,31,1:5
4Influence of acupuncture with exercise training on learning and memory functions, as well as microtubule-associated protein-2 and synaptophysin expression in the hippocampal CA3 region, in a rat model of cerebral infarction显示文摘The present study was designed to determine microtubule-associated protein-2 and synaptophysin expression in the hippocampal CA3 region in a rat model of middle cerebral artery occlusion. The rats were treated with acupuncture at Baihui (GV 20), Qubin (GB 7), and Qianding (GV 21) points, in addition to exercise training. Results were compared with rats undergoing exercise training only. The Y-maze method and immunohistochemistry revealed decreased error frequency of passing through Y-maze, as well as significantly increased microtubule-associated protein-2 and synaptophysin expression, in the acupuncture with exercise training group compared with the model and exercise training groups after 5 weeks. Microtubule-associated protein-2 and synaptophysin expressions negatively correlated with error frequency of passing through the Y-maze. These results suggested that acupuncture combined with exercise training improved learning and memory functions in a rat model of cerebral infarction. The mechanisms of action were hypothesized to be associated with dendritic or synaptic plasticity in the ipsilateral hippocampal CA3 region.Wei Jiang Liubing Li Min Yang Yanzhen Bi Kehui Hu Peng Zhang Yixin Shen Qian Yu 2011Neural Regeneration Research2011,6,27:4
5β-catenin activation in hair follicle dermal stem cells in duces ectopic hair outgrowth and skin fibrosis显示文摘Hair follicle dermal sheath(DS)harbors hair follicle dermal stem cells(hfDSCs),which can be recruited to replenish DS and dermal papilla(DP).Cultured DS cells can differentiate into various cell lineages in vitro.However,it is unclear how its plasticity is modulated in vivo.Wnt/β-catenin signaling plays an important role in maintaining stem cells of various lineages and is required for HF development and regeneration.Here we report that activation ofβ-catenin in DS generates ectopic HF outgrowth(EF)by reprogramming HF epidermal cells and DS cells themselves,and endows DS cells with hair inducing ability.Epidermal homeostasis of pre-existing HFs is disrupted.Additionally,cell-autonomous progressive skin fibrosis is prominent in dermis,where the excessive fibroblasts largely originate from DS.Gene expression analysis of purified DS cells with activatedβ-catenin revealed significantly increased expression of Bmp,Fgf,and Notch ligands and administration of Bmp,Fgf,or Notch signaling inhibitor attenuates EF formation.In summary,our findings advance the current knowledge of high plasticity of DS cells and provide an insight into understanding how Wnt/β-catenin signaling controls DS cell behaviors.Yixin Tao Qingchun Yang Lei Wang Jie Zhang Xuming Zhu Qianqian Sun Yunbin Han Qian Luo Yushu Wang Xizhi Guo Ji Wu Baojie Li Xiao Yang Lin He Gang Ma 2019Journal of Molecular Cell Biology2019,11,1:4
6Secondary battery inspired ɑ-nickel hydroxide as an efficient Ni-based heterogeneous catalyst for sulfate radical activation显示文摘Highly reactive radical species play an important role in syn-thetic chemistry, industrial processes, and environmental remedi-ation applications [1,2]. The radicals can be formed by eitherthermal decomposition of highly active oxidants or by catalyticactivation of stable oxidants under mild conditions [2]. Recently,the sulfate radical (.504) with its advantages of strong oxidizingpower, selective reactivity, and stability over a broad range of pHhas emerged as an excellent and versatile oxidant for a variety ofapplication [5].Dongting Yue Xufang Qian Meng Ren Mengyuan Fang Jinping Jia Yixin Zhao 2018Science Bulletin2018,63,5:2
7A simple fabrication of CH3NH3PbI3 perovskite for solar cells using low-purity PbI2显示文摘The CH3NH3PbI_3(MAPbI_3)perovskite was usually prepared by high-purity PbI_2 with high cost.The low cost and low-purity PbI_2 was seldom reported for fabrication of MAPW3 because it cannot even dissolve well in widely adopted solvent of DMF.We developed an easy method to adapt low-purity PbI_2 for fabrication of high quality MAPbI_3 just by the simple addition of some hydrochloric acid into the mixture of low-purity PbI_2,MAI and DMF.This straightforward method can not only help dissolve the low quality PbI_2 by reacting with some impurities in DMF,but also lead to a successful fabrication of high-quality perovskite solar cells with up to 14.80%efficiency comparable to the high quality PbI_2 precursors.Nanjie Guo Taiyang Zhang Ge Li Feng Xu Xufang Qian Yixin Zhao 2017Journal of Semiconductors2017,38,1:2
8Deletion of a Stay-Green Gene Associates with Adaptive Selection in Brassica napus显示文摘叶绿素层次响应改变环境关于植物生长和生理的粘性提供重要信息。停留绿色基因黄得非(NYE1 ) 1 被相信在老朽期间调整叶绿素降级,附随地影响轻收获的建筑群的拆卸并且间接地因此影响光合作用。我们识别了带与增加的叶绿素内容,并且与轻收获的复杂、光合的反应中心(希腊语的第二十三个字母和 PSII ) 的 upregulated 表示联系的 NYE1 删除的 Brassica 马来麝就职基因。有相关基因背景的就职的种子油内容的比较分析揭示了 B。马来麝 NYE1 基因删除(bnnye1 ) 影响了油累积,并且连接不平衡签名建议地点由在 oilseed B 繁殖服从于人工的选择。马来麝形式。在 allopolyploid B 的三不同生态型之间的 haplotype 差异组(haplogroups ) 的比较分析。马来麝和它的 A-subgenome 双祖先, Brassica rapa,从亚洲 B 显示了 bnnye1 删除的那基因渗入。rapa 进冬季类型 B。马来麝可能同时改进了它的改编到播种秋天的油菜籽经验丰富的更凉爽的环境。Lunwen Qian Kai Voss-Fels Yixin Cui Habib U. Jan Birgit Samans Christian Obermeier Wei Qian Rod J. Snowdon 2016Molecular Plant2016,9,12:2
9Genome-wide identi?cation of loci affecting seed glucosinolate contents in Brassica napus L.显示文摘Glucosinolates are amino acid-derived secondary metabolites that act as chemical defense agents against pests.However,the presence of high levels of glucosinolates severely diminishes the nutritional value of seed meals made from rapeseed(Brassica napus L.).To identify the loci affecting seed glucosinolate cont ent(SGC),we con ducted genome-wide resequencing in a population of 307 diverse B.napus accessions from the three B.napus ecotype groups,namely,spring,winter,and semi-winter.These resequencing data were used for a genome-wide association study(GWAS)to identify the loci affecting SGC.In the three ecotype groups,four comm on and four ecotype-specific haplotype blocks(HBs)were significantly associated with SGC.To identify candidate genes controlling SGC,transcriptome analysis was carried out in 36 accessions showing extreme SGC values.Analyses of haplotypes,genomic variation,and candidate gene expression pointed to five and three candidate genes in the common and spring group-specific HBs,respectively.Our expression analyses dem on strated that additive effects of the three candidate genes in the spring group-specific HB play important roles in the SGC of B.napus.Dayong Wei Yixin Cui Jiaqin Mei Lunwen Qian Kun Lu Zhi-Min Wang Jiana Li Qinglin Tang Wei Qian 2019Journal of Integrative Plant Biology2019,61,5:2
10New Algorithm Rules Out Acute-on-chronic Liver Failure Development within 28 Days from Acute Decompensation of Cirrhosis显示文摘Background and Aims:Approximately 10%of patients with acute decompensated(AD)cirrhosis develop acute-on-chronic liver failure(ACLF)within 28 days.Such cases have high mortality and are difficult to predict.Therefore,we aimed to establish and validate an algorithm to identify these patients on hospitalization.Methods:Hospitalized patients with AD who developed ACLF within 28 days were considered pre-ACLF.Organ dysfunction was defined accord-ing to the chronic liver failure-sequential organ failure as-sessment(CLIF-SOFA)criteria,and proven bacterial infec-tion was taken to indicate immune system dysfunction.A retrospective multicenter cohort and prospective one were used to derive and to validate the potential algorithm,re-spectively.A miss rate of<5%was acceptable for the calcu-lating algorithm to rule out pre-ACLF.Results:In the deri-vation cohort(n=673),46 patients developed ACLF within 28 days.Serum total bilirubin,creatinine,international normalized ratio,and present proven bacterial infection at admission were associated with the development of ACLF.AD patients with≥2 organ dysfunctions had a higher risk for pre-ACLF patients[odds ratio=16.58195%confidence interval:(4.271-64.363),p<0.001].In the derivation co-hort,67.5%of patients(454/673)had≤1 organ dysfunction and two patients(0.4%)were pre-ACLF,with a miss rate of 4.3%(missed/total,2/46).In the validation cohort,65.9%of patients(914/1388)had≤1 organ dysfunction,and four(0.3%)of them were pre-ACLF,with a miss rate of 3.4%(missed/total,4/117).Conclusions:AD patients with≤1 organ dysfunction had a significantly lower risk of developing ACLF within 28 days of admission and could be safely ruled out with a pre-ACLF miss rate of<5%.Xiaoting Tang Hai Li Guohong Deng Xin Zheng Xianbo Wang Yan Huang Yanhang Gao Zhongji Meng Zhiping Qian Feng Liu Xiaobo Lu Yu Shi Beiling Li Wenyi Gu Xiaomei Xiang Yan Xiong Yixin Hou Jun Chen Na Gao Sen Luo Liujuan Ji Jing Li Rongjiong Zheng Haotang Ren Jinjun Chen 2023Journal of Clinical and Translational Hepatology2023,11,3:1
11Effective removal of chlorinated organic pollutants by bimetallic iron-nickel sulfide activation of peroxydisulfate显示文摘Chlorinated organic pollutants(COPs)have caused serious contaminants in soil and groundwater,hence developing methods to remove these pollutants is necessary and urgent.By a simple hydrothermal method,we synthesized the bimetallic iron-nickel sulfide(FeNiS)particles which exhibited excellent catalytic property of COPs removal.FeNiS was chosen as the peroxydisulfate(PDS)activator to removal COPs including 4-chlorophenol(4-CP),1,4-dichlorophenol(1,4-DCP)and 2,4,6-trichlorophenol(2,4,6-TCP).The results show that FeNiS can efficiently activate PDS to produce sulfate radical(SO4·-)which plays major role in the oxidative dechlorination and degradation due to its strong oxidizing property and the ability of producing hydroxyl radicals(·OH)in the alkaline condition.Meanwhile,the Cl-abscised from COPs during the dechlorination can turn into the chlorine radicals and enhance the degradation and cause further mineralization of intermediate products.This bimetallic FeNiS catalyst is a promising PDS activator for removal of chlorinated organics.Xuan Yan Dongting Yue Chao Guo Songling Wang Xufang Qian Yixin Zhao 2020Chinese Chemical Letters2020,31,6:1
12LILRB4, an immune checkpoint on myeloid cells显示文摘Leukocyte immunoglobulin-like receptor B4(LILRB4)is an inhibitory receptor in the LILR family mainly expressed on normal and malignant human cells of myeloid origin.By binding to ligands,LILRB4 is activated and subsequently recruits adaptors to cytoplasmic immunoreceptor tyrosine inhibitory motifs to initiate different signaling cascades,thus playing an important role in physiological and pathological conditions,including autoimmune diseases,microbial infections,and cancers.In normal myeloid cells,LILRB4 regulates intrinsic cell activation and differentiation.In disease-associated or malignant myeloid cells,LILRB4 is significantly correlated with disease severity or patient survival and suppresses T cells,thereby participating in the pathogenesis of various diseases.In summary,LILRB4 functions as an immune checkpoint on myeloid cells and may be a promising therapeutic target for various human immune diseases,especially for cancer immunotherapy.Ting Yang Yixin Qian Xiaoting Liang Jianbo Wu Ming Zou Mi Deng 2022Blood Science2022,4,2:1
13Override control of furnace combustion system显示文摘Wei Huang Yixin Zhao Qian Qi 2008IEEE2008,12,4:1
14In vivo inducing collagen regeneration of biodegradable polymer microspheres显示文摘Biodegradable polymer particles have been used as dermal fillers for pre-clinical and clinical trials.The impact of material properties of polymers is very important to develop products for aesthetic medicine such as dermal fillers.Herein,eight biodegradable polymers with different molecular weights,chemical compositions or hydrophilic-hydrophobic properties were prepared and characterized for systematical study for aesthetic medicine applications.Polymer microspheres with 20-100 lmwere prepared.The in vitro degradation study showed that poly(L-lactic-co-glycolic acid)75/25 microspheres degraded the fastest,whereas poly(L-lactic acid)(PLLA)microspheres with intrinsic viscosity of 6.89([g]¼6.89)with the highest molecular weight showed the slowest degradation rate.After these microspheres were fabricated dermal fillers according to the formula of SculptraVR,they were injected subcutaneously into the back skin of rabbits.In vivo results demonstrated that the degradation rate of microspheres strongly correlated with the foreign body reaction and collagen regeneration was induced by microspheres.The microspheres with faster degradation rate induced inflammatory response and the collagen regeneration maintained in shorter time.PLLA([g]¼3.80)microsphere with a moderate molecular weight and degradation rate could strongly regenerate Type I and III collagen to maintain a long-term aesthetic medicine effect.These properties of size,morphology and degradation behavior would influence the foreign body reaction and collagen regeneration.Yixin Zhang Hanwen Liang Qian Luo Jianlin Chen Nan Zhao Wenxia Gao Yuji Pu Bin He Jing Xie 2021Regenerative Biomaterials2021,8,5:1
15Design of Implant Prosthesis for Bone Injury Repair Considering Stress Shielding Effect显示文摘The failure of bone injury repair surgery is mostly due to the stress shielding effect caused by the difference of elastic modulus between the implant prosthesis and human bone,result-ing in a great damage to patients.To solve this problem,in this study,the influencing factors of the elastic modulus of implant prosthesis were investigated,the relationship between the elastic modulus of the implanted prosthesis and the influencing factors was analyzed,and then a design method of the implant prosthesis to reduce the stress shielding effect by adjusting the unit module to control the elastic modulus was established.This method was used for the biomechanical simula-tion to simulate the displacement and stress distribution between the implant prosthesis and the surrounding bone tissue,and then the reliability of the method was verified.The implant prosthe-sis with an elastic modulus consistent with that of the experimental dog bone was made by this method,and used for the animal experiments.The effects of implant prosthesis with different mod-ulus on the growth of surrounding bone tissue were observed,and at the same time,the reliability of the implant design method and the results of biomechanical simulation were verified.It is con-firmed that this method can effectively reduce the stress concentration of implant prosthesis by more than 15.4%and increase the growth of bone tissue by more than 21%.Yixin Shao Ye Zhu Tianmin Guan Qi Hu Baozhong Wei Bing Lin Liyan Zhang Qian Cao 2022Journal of Beijing Institute of Technology2022,31,3:0
16Translational oncology toward benefiting cancer patients:the Sun Yat-sen University Cancer Center experience显示文摘Cancer is a leading cause of death in China with an estimation of nearly 2 million deaths every year(Chen and Fu,2011b).Matter of a public health importance in China and worldwide,the scientific community is still facingMathilde Guerin Chaonan Qian Qian Zhong Qian Cui Yunmiao Guo Jinxin Bei Jianyong Shao Xiaofeng Zhu Wenlin Huang Jiangxue Wu Ranyi Liu Qiang Liu Jing Wang Weihua Jia Xiaohui Zheng Yixin Zeng 2016Science China(Life Sciences)2016,59,10:0
17Mechanochemically sulfured FeS1.92 as stable and efficient heterogeneous Fenton catalyst显示文摘Fenton reaction is one of most promising approaches for efficient removal of various robust organic pollutants in wastewater,however it faces several intrinsic challenges such as acidic condition,sludge waste and sensitive to sulfide-containing compound.Here we reported a novel FeS1.92 as an efficient and sulfide resistant heterogeneous Fenton catalyst under mild condition.This novel FeS1.92 was facilely prepared through a mechanochemical synthesis of mackinawite(FeS) with sulfur powder(S) by ball milling.The sulfured mackinawite(FeS1.92) exhibits high performance in activating H2 O2 to generate hydroxyle radicals for organic waste remediation.Furthermore,this FeS1.92 based heterogeneous Fenton catalyst is highly sulfide resistant and shows improved performance for degrading sulfide-containing organic pollutants.This study provides an effective mechanochemical approach to fabricate heterogeneous Fenton catalysts for sulfide-containing wastewater treatment.Chao Guo Dongting Yue Songling Wang Xufang Qian Yixin Zhao 2020Chinese Chemical Letters2020,31,7:0
18The DDB1-DCAF2 complex is essential for B cell development because it regulates cell cycle progression显示文摘B cell development in the bone marrow is critical for producing numerous B cells that play an essential role in the adaptive immune response.B cells develop from common lymphoid progenitors(CLPs),which then differentiate through a series of stages,which include prepro-B cells,pro-B cells,pre-B cells,immature B cells,and mature B cells.Zhonghui Xue Jing Guo Ruoyu Ma Lina Zhou Yixin Guo Yong Cang Hengyu Fan Jian Chen Wenbin Qian Lie Wang 2021Cellular & Molecular Immunology2021,18,3:0
19In-situ formation of nitrogen doped microporous carbon nanospheres derived from polystyrene as lubricant additives for anti-wear and friction reduction显示文摘This study presents a nitrogen-doped microporous carbon nanospheres(N@MCNs)prepared by a facile polymerization–carbonization process using low-cost styrene.The N element in situ introduces polystyrene(PS)nanospheres via emulsion polymerization of styrene with cyanuric chloride as crosslinking agent,and then carbonization obtains N@MCNs.The as-prepared carbon nanospheres possess the complete spherical structure and adjustable nitrogen amount by controlling the relative proportion of tetrachloromethane and cyanuric chloride.The friction performance of N@MCNs as lubricating oil additives was surveyed utilizing the friction experiment of ball-disc structure.The results showed that N@MCNs exhibit superb reduction performance of friction and wear.When the addition of N@MCNs was 0.06 wt%,the friction coefficient of PAO-10 decreased from 0.188 to 0.105,and the wear volume reduced by 94.4%.The width and depth of wear marks of N@MCNs decreased by 49.2% and 94.5%,respectively.The carrying capacity of load was rocketed from 100 to 400 N concurrently.Through the analysis of the lubrication mechanism,the result manifested that the prepared N@MCNs enter clearance of the friction pair,transform the sliding friction into the mixed friction of sliding and rolling,and repair the contact surface through the repair effect.Furthermore,the tribochemical reaction between nanoparticles and friction pairs forms a protective film containing nitride and metal oxides,which can avert direct contact with the matrix and improve the tribological properties.This experiment showed that nitrogen-doped polystyrene-based carbon nanospheres prepared by in-situ doping are the promising materials for wear resistance and reducing friction.This preparing method can be ulteriorly expanded to multi-element co-permeable materials.Nitrogen and boron co-doped carbon nanospheres(B,N@MCNs)were prepared by mixed carbonization of N-enriched PS and boric acid,and exhibited high load carrying capacity and good tribological properties.Yixin WANG Qi LU Huijie XIE Shujuan LIU Qian YE Feng ZHOU Weimin LIU 2024Friction2024,12,3:0
20Identification of a candidate QTG for seed number per silique by integrating QTL mapping and RNA-seq in Brassica napus L.显示文摘Seed number per silique(SNPS)is one of seed yield components in rapeseed,but its genetic mechanism remains elusive.Here a double haploid(DH)population derived from a hybrid between female 6Q006with 35–40 SNPS and male 6W26 with 10–15 SNPS was investigated for SNPS in the year 2017,2018,2019 and 2021,and genotyped with Brassica 60K Illumina Infinium SNP array.An overlapping major QTL(qSNPS.C09)explaining 51.50%of phenotypic variance on average was narrowed to a 0.90 Mb region from 44.87 Mb to 45.77 Mb on chromosome C09 by BSA-seq.Subsequently,two DEGs in this interval were detected between extreme individuals in DH and F_2populations by transcriptome sequencing at7 and 14 days after pollination siliques.Of which,BnaC09g45400D encoded an adenine phosphoribosyltransferase 5(APT5)has a 48-bp InDel variation in the promoter of two parents.Candidate gene association analysis showed that this InDel variation was associated with SNPS in a nature population of rapeseed,where 54 accessions carrying the same haplotype as parent 6Q006 had higher SNPS than103 accessions carrying the same haplotype as parent 6W26.Collectively,the findings are helpful for rapeseed molecular breeding of SNPS,and provide new insight into the genetic and molecular mechanism of SNPS in rapeseed.Shuangshuang Xin Hongli Dong Yixin Cui Yilin Liu Guifu Tian Nanxi Deng Huafang Wan Zhi Liu Xiaorong Li Wei Qian 2023The Crop Journal2023,11,1:0
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