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| 1 | Diaphragm disease compared with cryptogenic multifocal ulcerous stenosing enteritis显示文摘As the use of drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs) increases,so too do gastrointestinal ulcers,bleeding,perforation and obstruction.Diaphragm disease of the small intestine is formed by submucosal fibrosis and destruction of lamina muscularis due to chronic ulceration,which corresponds to the most severe stage of NSAID enteropathy.It may lead to stricture of the small intestine.If such ulcerations and strictures in the small intestine are multiple,differential diagnosis is between diaphragm disease and cryptogenic multifocal ulcerous stenosing enteritis (CMUSE),because the gross findings of diaphragm disease are similar to those of CMUSE.We report a rare case of diaphragm disease caused by NSAID.It has been finally confirmed by capsule endoscopy and the origin of chronic obscure gastrointestinal bleeding was found to be multiple ulcers and strictures in the small intestine.After operation,we diagnosed the patient with diaphragm disease rather than CMUSE. | Sook Hee Chung Yunju Jo Sang Ryol Ryu Sang Bong Ahn Byoung Kwan Son Seong Hwan Kim Young Sook Park Young Ok Hong | 2011 | World Journal of Gastroenterology2011，17，23： | 5 |
| 2 | Analysis on sports and recreation activity-related eye injuries presenting to the Emergency Department显示文摘AIM:To investigate the incidence and general characteristics of sports-related eye injuries in patients visiting the Emergency Department. METHODS: A cross-sectional,multi-center,observational study.Patients with an injured eye who visited the Emergency Department at one of nine hospitals in Korea were enrolled.All data were prospectively collected between March and September 2010 using a questionnaire.Eye injuries that occurred during risky sports were examined by gender and age.Additionally,the rate of open globe injuries that occurred with and without protective eyewear was examined for each activity.Continuous variables were compared using Student's t-test and categorical variables were compared using Chi-square test.RESULTS: A total of 446 patients had sports-related eye injuries.Teenagers(10-19 years old) and young adults(20-29 years old) had the most eye injuries.Eye injuries accounted for 0.2% of Emergency Department patients.Baseball was the most common cause of sports-related eye injuries,followed by soccer and hiking.Protective gear was worn by 9.4% of all patients.Patients that were 30-39 years of age had the highest rate of protective gear use,followed by patients that were 40-49 years of age.The proportion of sports-related eye injuries that were open-globe injuries was highest for soccer and hiking.CONCLUSION: Although injuries were most common in patients below the age of 10 years,these patients had the lowest rate of protective eyewear use.Injuries in adults over 40 years of age most commonly occurred during hiking,but the rate of protective eyewear use was low.Young athletes should be educated on and provided with protective eyewear and policies protective gear use should be established.For older adults,eye protection should be encouraged,especially during hiking. | Sungbae Moon Hyun Wook Ryoo Jae Yun Ahn Jung Bae Park Kang Suk Seo Sang Do Shin Kyoung Jun Song Kang Hyun Lee In Sool Yoo Jin Seong Cho Hyun Ho Ryu Tae Oh Jeong Seok Ran Yeom Young Taek Kim Sung Ok Hong | 2016 | International Journal of Ophthalmology(English edition)2016，9，10： | 3 |
| 3 | Whole-genome,transcriptome,and methylome analyses provide insights into the evolution of platycoside biosynthesis in Platycodon grandiflorus,a medicinal plant显示文摘Triterpenoid saponins(TSs)are common plant defense phytochemicals with potential pharmaceutical properties.Platycodon grandiflorus(Campanulaceae)has been traditionally used to treat bronchitis and asthma in East Asia.The oleanane-type TSs,platycosides,are a major component of the P.grandiflorus root extract.Recent studies show that platycosides exhibit anti-inflammatory,antiobesity,anticancer,antiviral,and antiallergy properties.However,the evolutionary history of platycoside biosynthesis genes remains unknown.In this study,we sequenced the genome of P.grandiflorus and investigated the genes involved in platycoside biosynthesis.The draft genome of P.grandiflorus is 680.1 Mb long and contains 40,017 protein-coding genes.Genomic analysis revealed that the CYP716 family genes play a major role in platycoside oxidation.The CYP716 gene family of P.grandiflorus was much larger than that of other Asterid species.Orthologous gene annotation also revealed the expansion ofβ-amyrin synthases(bASs)in P.grandiflorus,which was confirmed by tissue-specific gene expression.In these expanded gene families,we identified key genes showing preferential expression in roots and association with platycoside biosynthesis.In addition,wholegenome bisulfite sequencing showed that CYP716 and bAS genes are hypomethylated in P.grandiflorus,suggesting that epigenetic modification of these two gene families affects platycoside biosynthesis.Thus whole-genome,transcriptome,and methylome data of P.grandiflorus provide novel insights into the regulation of platycoside biosynthesis by CYP716 and bAS gene families. | Jungeun Kim Sang-Ho Kang Sin-Gi Park Tae-Jin Yang Yi Lee Ok Tae Kim Oksung Chung Jungho Lee Jae-Pil Choi Soo-Jin Kwon Keunpyo Lee Byoung-Ohg Ahn Dong Jin Lee Seung-il Yoo In-Gang Shin Yurry Um Dae Young Lee Geum-Soog Kim Chang Pyo Hong Jong Bhak Chang-Kug Kim | 2020 | Horticulture Research2020，7，1： | 2 |
| 4 | Histological improvement following administration of autologous bone marrow‐derived mesenchymal stem cells for alcoholic cirrhosis: a pilot study显示文摘 | Yoon Ok Jang Young Ju Kim Soon Koo Baik Moon Young Kim Young Woo Eom Mee Yon Cho Hong Jun Park So Yeon Park Bo Ra Kim Jae Woo Kim Hyun Soo Kim Sang Ok Kwon Eun Hee Choi Yong Man Kim | 2014 | Liver Int2014，，1： | 2 |
| 5 | Functional characterization of naturally occurring melittin peptide isoforms in two honey bee species, Apis mellifera and Apis cerana显示文摘 | Doori Park Je Won Jung Mi Ok Lee Si Young Lee Boyun Kim Hye Jun Jin Jiyoung Kim Young-Joon Ahn Ki Won Lee Yong Sang Song Seunghun Hong James E. Womack Hyung Wook Kwon | 2014 | Peptides2014，，： | 1 |
| 6 | Hepatogenous Diabetes in Cirrhosis Is Related to Portal Pressure and Variceal Hemorrhage显示文摘 | Hyo Keun Jeon Moon Young Kim Soon Koo Baik Hong Jun Park Hoon Choi So Yeon Park Bo Ra Kim Jin Heon Hong Ki Won Jo Seung Yong Shin Jung Min Kim Jae Woo Kim Hyun Soo Kim Sang Ok Kwon Young Ju Kim Seung Hwan Cha Dong Joon Kim Ki Tae Suk Gab Jin Cheon Young D | 2013 | Digestive Diseases and Sciences2013，，11： | 1 |
| 7 | Risk factors for cholecystitis after metal stent placement in malignant biliary obstruction <ce:link locator='fx1'/>显示文摘 | Ki Tae Suk Hyun Soo Kim Jae Woo Kim Soon Koo Baik Sang Ok Kwon Ho Gak Kim Don Haeng Lee Byung Moo Yoo Jin Hong Kim Young Soo Moon Dong Ki Lee | 2006 | Gastrointestinal Endoscopy2006，，4： | 1 |
| 8 | Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis with Sleep Deprivation: Possible Mechanism by Microarray Analysis显示文摘 | Sook Hee Chung Young Sook Park Ok Soon Kim Ja Hyun Kim Haing Woon Baik Young Ok Hong Sang Su Kim Jae-Ho Shin Jin-Hyun Jun Yunju Jo Sang Bong Ahn Young Kwan Jo Byoung Kwan Son Seong Hwan Kim | 2014 | Digestive Diseases and Sciences2014，，6： | 1 |
| 9 | Malignant sweat gland tumor of breast arising in pre-existing benign tumor: A case report显示文摘BACKGROUND Sweat glands belong to skin appendages.Sweat gland tumors are uncommon,especially when they occur as malignant tumors in the breast.We report a case of malignant sweat gland tumor of the breast,including imaging and pathological findings.CASE SUMMARY A 47-year-old woman visited our hospital with a non-tender palpable lesion in her left breast.The lesion had not shown changes for 10 years.However,it recently increased in size.Sonography showed a well circumscribed cystic lesion with internal debris and fluid-fluid level.Magnetic resonance imaging showed a well circumscribed oval mass with T1 hyper-intensity compared to muscle and T2 high signal intensity.There was a small enhancing mural component in the inner wall of the mass.The tumor was resected.Its pathologic result was a malignant transformation of benign sweat gland tumor such as hidradenoma.The lesion was treated with excision and radiation therapy.At 1-year follow up,there was no local recurrence or metastasis in the patient.CONCLUSION In the case of a rapid growing cystic mass in the nipple and subareola,it is necessary to distinguish it from a malignant sweat gland tumor. | Jin Kyung An Jeong Joo Woo Young Ok Hong | 2019 | World Journal of Clinical Cases2019，7，19： | 0 |
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