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| 1 | SIZ1-Mediated SUMOylation of TPR1 Suppresses Plant Immunity in Arabidopsis显示文摘Plant immune responses are tightly regulated to ensure their appropriate deployment. Overexpression of TOPLESS-RELATED 1 (TPR1), a SUPPRESSOR OF npr1-1, CONSTITUTIVE 1 (SNC1)-interacting protein, results in autoimmunity that reduces plant growth and development. However, how TPR1 activity is regulated remains unknown. Loss of function of SIZ1, a (SUMO) E3 ligase, induces an autoimmune response, partially due to elevated SNC1 levels. Here we show that SNC1 expression is upregulated in Arabidopsis thaliana siz1-2 due to positive-feedback regulation by salicylic acid. SIZ1 physically interacts with TPR1 and facilitates its SUMO modification. The K282 and K721 residues in TPR1 serve as critical SUMO attachment sites. Simultaneous introduction of K282R and K721R substitutions in TPR1 blocked its SUMOylation, enhaneed its transcriptional co-repressor activity, and increased its association with HISTONE DEACETYLASE 19 (HDA19), suggesting that SUMOylation of TPR1 represses its transcriptional co-repressor activity and inhibits its interaction with HDA19. In agreement with this finding, the simultaneous introduction of K282R and K721R substitutions enhanced TPR1 mediated immunity, and the tpr1 mutation partially suppressed autoimmunity in siz1-2. These results demonstrate that SIZ1-mediated SUMOylation of TPR1 represses plant immunity, which at least partly contributes to the suppression of autoimmunity under nonpathogenic conditions to ensure proper plant development. | De Niu Xiao-Li Lin Xiangxiong Kong Gao-Ping Qu Bin Cai Jiyoung Lee Jing Bo Jin | 2019 | Molecular Plant2019，12，2： | 9 |
| 2 | Cryptogenic multifocal ulcerous stenosing enteritis: Radiologic features and clinical behavior显示文摘AIM To investigate the characteristic radiologic findings of cryptogenic multifocal ulcerous stenosing enteritis(CMUSE) which can be differentiated from other similar bowel disease and to assess their clinical behavior.METHODS Twenty pathologically and clinically confirmed CMUSE patients(males:females = 8:12; mean age: 40.4 years) between March 2002 and August 2015 from seven academic centers in South Korea were retrospectively reviewed. We evaluated small bowel series(SBS; n = 25), computed tomography(CT) enterography(n = 21), magnetic resonance(MR) enterography(n = 2), and abdominopelvic CT(n = 18) images, focusing on enteric and perienteric manifestations. Any change in radiologic features during followup period was recorded. We evaluated clinical data including presenting symptoms, laboratory finding and presence of relapse from electronic medical records. Histopathologic findings were also evaluated. RESULTS The main symptoms were abdominal pain(n = 12) and anemia(n = 10). All patients showed small bowel strictures(n = 52, mean: 2.6 per patient) on initial CT/MR, located in the ileum(n = 47) or jejunum(n = 5). Strictures showed short-length(mean: 10.44 mm) and circumferential bowel wall thickening(mean: 5.56 mm) with layered enhancement(n = 48) that were also noted on initial SBS(n = 36) with shallow ulcers(n = 10). Some ulcerative lesions or wall thickening progressed into strictures on follow-up SBS/CT, and some strictures revealed recurrent ulceration on followup SBS. There were no penetrating disease features like fistula or abscess and no gastrointestinal tract involvement except the small bowel. Nine patients experienced disease recurrence(median relapse-free period: 32 mo) even post-operatively. Histopathologic features of surgically resected specimens were characterized as multiple superficial ulcerations confined to mucosa or submucosa and multiple strictures.CONCLUSION Under characteristic radiologic findings with multiple short-segmental strictures and/or shallow ulcers of the small intestine, CMUSE should be considered when assessing patients with recurrent abdominal pain and anemia. | Jiyoung Hwang Jin Sil Kim Ah Young Kim Joon Seok Lim Se Hyung Kim Min Ju Kim Mi Sung Kim Kyoung Doo Song Ji Young Woo | 2017 | World Journal of Gastroenterology2017，23，25： | 4 |
| 3 | A Sub-Nanostructural Transformable Nanozyme for Tumor Photocatalytic Therapy显示文摘The structural change-mediated catalytic activity regulation plays a significant role in the biological functions of natural enzymes.However,there is virtually no artificial nanozyme reported that can achieve natural enzyme-like stringent spatiotemporal structure-based catalytic activity regulation.Here,we report a subnanostructural transformable gold@ceria(STGC-PEG)nanozyme that performs tunable catalytic activities via near-infrared(NIR)light-mediated sub-nanostructural transformation.The gold core in STGC-PEG can generate energetic hot electrons upon NIR irradiation,wherein an internal sub-nanostructural transformation is initiated by the conversion between CeO;and electron-rich state of CeO;-x,and active oxygen vacancies generation via the hot-electron injection.Interestingly,the sub-nanostructural transformation of STGC-PEG enhances peroxidase-like activity and unprecedentedly activates plasmon-promoted oxidase-like activity,allowing highly efficient low-power NIR light(50 m W cm;)-activated photocatalytic therapy of tumors.Our atomic-level design and fabrication provide a platform to precisely regulate the catalytic activities of nanozymes via a light-mediated sub-nanostructural transformation,approaching natural enzyme-like activity control in complex living systems. | Xi Hu Nan Wang Xia Guo Zeyu Liang Heng Sun Hongwei Liao Fan Xia Yunan Guan Jiyoung Lee Daishun Ling Fangyuan Li | 2022 | Nano-Micro Letters2022，14，6： | 4 |
| 4 | Regional Distribution of Perceived Temperatures Estimated by the Human Heat Budget Model (the Klima-Michel Model) in South Korea显示文摘The regional distribution of perceived temperatures (PT) for 28 major weather stations in South Korea during the past 22 years (1983–2004) was investigated by employing a human heat budget model, the Klima-Michel model. The frequencies of a cold stress and a heat load by each region were compared. The sensitivity of PT in terms of the input of synoptic meteorological variables were successfully tested. Seogwipo in Jeju Island appears to be the most comfortable city in Korea. Busan also shows a high frequency in the comfortable PT range. The frequency of the thermal comfort in Seoul is similar to that of Daejeon with a relatively low frequency. In this study, inland cities like Daegu and Daejeon had very hot thermal sensations. Low frequencies of hot thermal sensations appeared in coastal cities (e.g., Busan, Incheon, and Seogwipo). Most of the 28 stations in Korea exhibited a comfort thermal sensation over 40% in its frequency, except for the mountainous regions. The frequency of a heat load is more frequent than that of a cold stress. There are no cities with very cold thermal sensations. In this study, we found the decreasing trend of mortality with an increasing PT. If the PT is over any critical temperature point, however, the mortality rate increases again. The mortality variation with the PT of a station seems to be associated with the latitudinal location of the station, implying that it results from a regional acclimation effect of inhabitants. | Jiyoung KIM Kyu Rang KIM Byoung-Cheol CHOI Dae-Geun LEE Jeong-Sik KIM | 2009 | Advances in Atmospheric Sciences2009，26，2： | 4 |
| 5 | -pigenetic modifications and self-renewal regulation of ~ouse germline stem cells显示文摘 | Jiyoung Lee | 2011 | Cell Research2011，21，8： | 2 |
| 6 | A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders显示文摘 | Jiyoung Kim Young-Nam Cha Young-Joon Surh | 2009 | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis2009，，1： | 2 |
| 7 | Carbide precipitation kinetics in austenite of a Nb–Ti–V microalloyed steel显示文摘 | Jae-Gil Jung June-Soo Park Jiyoung Kim Young-Kook Lee | 2011 | Materials Science & Engineering A2011，，16： | 2 |
| 8 | Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice显示文摘 | Ae-Sim Cho Seon-Min Jeon Myung-Joo Kim Jiyoung Yeo Kwon-Il Seo Myung-Sook Choi Mi-Kyung Lee | 2010 | Food and Chemical Toxicology2010，，： | 2 |
| 9 | Generation of Pluripotent Stem Cells from Neonatal Mouse Testis显示文摘 | Mito Kanatsu-Shinohara Kimiko Inoue Jiyoung Lee Momoko Yoshimoto Narumi Ogonuki Hiromi Miki Shiro Baba Takeo Kato Yasuhiro Kazuki Shinya Toyokuni Megumi Toyoshima Ohtsura Niwa Mitsuo Oshimura Toshio Heike Tatsutoshi Nakahata Fumitoshi Ishino Atsuo Ogura T | 2004 | Cell2004，，7： | 2 |
| 10 | Modulating charge carriers in carbon dots toward efficient solar-to-energy conversion显示文摘Growing attention to the development of sustainable solar-to-energy conversion applications has resulted in the synthesis of promising and environment-friendly nanomaterials as energy harvesters.Among various carbon nanomaterials,carbon dots(CDs)have received significant attention due to their excellent light absorption capability,broad absorption region,and superior photostability with enormous potential for solar energy applications.Therefore,utilizing and modulating the charge carriers generated from CDs is critical for achieving a high energy conversion efficiency of CDs.Herein,we focus on the distinct characteristics of CDs as energy converters from charge excitation to charge separation and transfer for various solar-to-energy applications,including photovoltaic cells,photocatalysts,and photoelectrocatalysts.We anticipate that this review will offer insight into the synthesis and design of novel nanocomposites with a fundamental analysis of the photochemical properties and future development of energy conversion devices. | Namhee Kim Jiyoung Lee Minsu Gu Byeong-Su Kim | 2021 | Carbon Energy2021，3，4： | 2 |
| 11 | Identification of syn andanti-anethole-2,3-epoxides in the metabolism of transanethole by the newly isolated bacterium Pseudornonas putida JYR-1显示文摘 | Jiyoung Ryu Jiyoung Seo Youngshim Lee | 2005 | Journal of Agricultural and Food Chemistry2005，53，15： | 1 |
| 12 | Reduction of rutin loss in buckwheat noodles and their physicochemical characterisa- tion显示文摘 | Jiyoung Yoo Yujenong Kim | 2012 | Food Chemistry2012，132，4： | 1 |
| 13 | The SUMO E3 ligase, AtSIZ1, regulates flowering by controlling a salicylic acid- mediated floral promotion pathway and through affects on FLC chromatin structure 显示文摘 | JING B J YIN H J JIYOUNG L | 2008 | The Plant Journal2008，53，： | 1 |
| 14 | Usage of video sharing websites: Drivers and barriers 显示文摘 | Jiyoung Cha | 2012 | Telematics and Informatics2012，，： | 1 |
| 15 | Formation of crack-free MoSi2/α-Si3 N4 composite coating on Mo substrate by ammonia nitridation of M% Si3 layer followed by chemical vapor deposition of Si显示文摘 | Yoon Jinkook Kim Gyeungho Byun Jiyoung | 2003 | Surface and Coatings Technology2003，165，1： | 1 |
| 16 | Temperature responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells显示文摘 | Jiyoung M Danga Daniel DN | 2006 | Biomaterials2006，27，： | 1 |
| 17 | Jacaranoneand Related Compounds from the Fresh Fruits of Ternstroemiajaponica and their Antioxidative Activity显示文摘 | Youngmi Jo Jiyoung Suh Myoung Hee Shin | 2005 | Arch pharm Res2005，28，8： | 1 |
| 18 | Web- based Intranet Services and Network Management显示文摘 | Wonki J Hong Jiyoung Kong Tae-Hyoung | 1997 | IEEE Communication Magazine1997，35，10： | 1 |
| 19 | Identification of syn- and anti-anethole-2,3-epoxides in the metabolism of trans-anethole by the newly isolated Bacterium Pseudomonas Putida JYR-I显示文摘 | Jiyoung Ryu Jiyoung Seo Youngshim Lee | 2005 | Agric Food Chem2005，53，15： | 1 |
| 20 | 孔有效利用的活性炭基非对称电极膜/电容脱盐系统(英文)显示文摘采用活性炭纤维为原料制备出膜/电容脱盐系统,提纯含氯化钠的水。OG系列活性炭纤维作为电极的活性材料,其比表面积和孔分布不同而呈现不同的活化程度。将这些材料用于膜/电容脱盐系统,评价了他们对钠离子或氯离子的脱盐性能。膜/电容实验在不同操作电位窗口、含盐溶液的进料速率和浓度下进行。OG系列活性炭纤维对每种离子的脱盐效率和电吸附量来评价膜/电容性能。结果表明,BET比表面积是确保高性能的必要因素。另外,炭材料最上端的浅孔有助于活性炭纤维比表面积的充分利用。OG7A样品的孔结构适合于钠离子吸附,OG10A和OG15A适于大量孔吸附氯离子。因此,非对称电极排列施加于吸附离子的尺寸,应考虑炭材料比表面积和孔面积的有效利用,以得到高性能的膜/电容脱盐系统。 | Jiyoung Kim Dong-Hyun Peck Byungrok Lee Seong-Ho Yoon Doo-Hwan Jung | 2016 | 新型炭材料2016，31，4： | 1 |
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