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| 1 | Immune responses against SARS-coronavirus nucleocapsid protein induced by DNA vaccine显示文摘 | Zhao P Cao J Zhao LJ Ke JS Pan W Ren H Yu JG Qi ZT | 2005 | 第二军医大学学报2005,26,10: | 12 |
| 2 | Role of stem cell therapies in treating chronic wounds:A systematic review显示文摘BACKGROUND The impairment of cutaneous wound healing results in chronic,non-healing wounds that are caused by altered wound environment oxygenation,tissue injury,and permissive microbial growth.Current modalities for the treatment of these wounds inadequately address the complex changes involved in chronic wound pathogenesis.Consequently,stem cell therapies have emerged as a potential therapeutic modality to promote cutaneous regeneration through trophic and paracrine activity.AIM To investigate current literature regarding use of stem cell therapies for the clinical treatment of chronic,non-healing wounds.METHODS PubMed,EMBASE,Cochrane Library,Web of Science,and Scopus were queried with combinations of the search terms“mesenchymal stem cells,”“adult stem cells,”“embryonic stem cells,”“erythroid precursor cells,”“stem cell therapies,”and“chronic wounds”in order to find relevant articles published between the years of 2000 and 2019 to review a 20-year experience.Reference lists from the articles were reviewed to identify additional pertinent articles.Retrieved manuscripts(reviews,case reports/series,retrospective/prospective studies,and clinical trials)were evaluated by the authors for their depiction of clinical stem cell therapy use.Data were extracted from the articles using a standardized collection tool.RESULTS A total of 43 articles describing the use of stem cell therapies for the treatment of chronic wounds were included in this review.While stem cell therapies have been explored in in vitro and in vivo applications in the past,recent efforts are geared towards assessing their clinical role.A review of the literature revealed that adipose-derived stem cells,bone marrow-derived stem cells,bone marrowderived mononuclear cells,epidermally-derived mesenchymal stem cells,fibroblast stem cells,keratinocyte stem cells,placental mesenchymal stem cells,and umbilical cord mesenchymal stem cells have all been employed in the treatment of chronic wounds of various etiologies.Most recently,embryonic stem cells have emerged as a novel stem cell therapy with the capacity for multifaceted germ cell layer differentiation.With the capacity for self-renewal and differentiation,stem cells can enrich existing cell populations in chronic wounds in order to overcome barriers impeding the progression of wound healing.Further,stem cell therapies can be utilized to augment cell engraftment,signaling and activity,and resultant patient outcomes.CONCLUSION Assessing observed clinical outcomes,potential for stem cell use,and relevant therapeutic challenges allows wound care stakeholders to make informed decisions regarding optimal treatment approaches for their patients’chronic wounds. | Anjali C Raghuram Roy P Yu Andrea Y Lo Cynthia J Sung Melissa Bircan Holly J Thompson Alex K Wong | 2020 | World Journal of Stem Cells2020,12,7: | 5 |
| 3 | Reproducibility of the diagnosis of dysplasia in Barrett esophagus: A reaffirmation显示文摘 | Elizabeth Montgomery Mary P Bronner John R Goldblum Joel K Greenson Marian M Haber John Hart Laura W Lamps Gregory Y Lauwers Audrey J Lazenby David N Lewin Marie E Robert Alicia Y Toledano Yu Shyr Kay Washington | 2001 | Human Pathology2001,,4: | 3 |
| 4 | Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries显示文摘冠的动脉把血流动带到心肌肉。理解冠的动脉的发展程序提供卓见进冠的动脉疾病的治疗。多重来源被描述了为包括 proepicardium,湾穴 venosus (SV ) ,和心内膜贡献冠的动脉。然而,冠的容器的发展起源仍然在强烈学习下面。我们为学习冠的开发生产了一个新基因工具,一只 AplnCreER 老鼠在开发冠的容器明确地衬里 recombinase,它表示可诱导的 Cre。冠的开发和 AplnCreER 命运跟踪的预定正式就职的定量分析证明 subepicardial endothelial 房间(EC ) 的子孙两个都入侵紧缩的心肌层形成冠的动脉并且在表面上留下生产静脉。我们发现这些 subepicardial EC 是 intramyocardial 的主要来源在发展中的心的冠的容器。在 vitro 将生物的活组织移植于培养基中培养,试金显示这些 subepicardial EC 的多数从 SV 和中庭的心内膜,然而并非从室的心内膜产生。Apln 积极的房间的同种细胞的分析显示单个 subepicardial EC 同等地作出贡献到冠的动脉和静脉。一起,这些数据建议 subepicardial EC 是 intramyocardial 的主要来源在室的冠的动脉墙,和那冠的动脉和静脉在发展中的心有普通起源。 | Xueying Tian Tianyuan Hu Hui Zhang Lingjuan He Xiuzhen Huang Qiaozhen Liu Wei Yu Liang He Zhongzhou Yang Zhen Zhang Tao P Zhong Xiao Yang Zhen Yang Yan Yan Antonio Baldini Yunfu Sun Jie Lu Robert J Schwartz Sylvia M Evans Adriana C Gittenberger-de Groot Kristy Red-Horse Bin Zhou | 2013 | Cell Research2013,23,9: | 3 |
| 5 | 显示文摘 | Shekunov B Yu Baldyga J York P | 2001 | Chemical Engineering Science2001,56,: | 2 |
| 6 | Using a hash-based method with transaction trimming for mining association rules 显示文摘 | J S Park M S Chen P S Yu | 1997 | IEEE Transactions on Knowledge and Data Engineering1997,9,: | 2 |
| 7 | A parallel sort merge JOIN algorithm for managing data skew显示文摘 | Wolf J L Dias D M Yu P S | 1993 | IEEE Transactions Parallel and Distributed Systems1993,4,1: | 2 |
| 8 | Durable Asphalt Pavements Are Self Healing显示文摘The traffic volume and the number of heavy vehicles are growing continuously. Considering the continuous traffic flow and the limited time available for road maintenance,it is very important to design a durable pavement system. Asphalt pavements with a healing capability are believed to be very useful since they can extend the pavement service life thanks to rest periods and hot summers. In order to design durable asphalt pavements,research in understanding and upgrading the self-healing capability of bituminous materials in time is of major importance. The self healing capability of bituminous mastic was evaluated in this research with a direct tension healing test. In the test program,different healing times,crack status and modifications were applied. The results indicate that elastic recovery and flow capacity are important factors for the self healing capability of bituminous materials at different crack phases as simulated with the direct tension test. | QIU J VAN DE VEN M F C WU S P YU J Y MOLENAAR A A A | 2010 | 武汉理工大学学报2010,32,17: | 2 |
| 9 | Measurement of piezoelectrically induced charge in GaN/A1GaN heterostructure field - effect transistors 显示文摘 | Yu E T Sullivan G J Asbeck P M | 1997 | Appl Phys Lett1997,71,19: | 1 |
| 10 | Data mining: An overview from a database perspective 显示文摘 | CHEN M S HAN J H YU P S | 1996 | IEEE Transactions on Knowledge and Data Engineering1996,8,6: | 1 |
| 11 | Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy 显示文摘 | Li Y Yu J | 2004 | Nature2004,429,6992: | 1 |
| 12 | Distal Watermarking Based on Neural Networks for Color Images显示文摘 | Yu P T Tsai H H Lin J S | 2001 | Signal Processing2001,81,3: | 1 |
| 13 | Design of a variable path tandem layout for automated guided vehicle systems显示文摘 | Yu W Egbelu P J | 2001 | Journal of Manufacturing Systems2001,20,5: | 1 |
| 14 | Data mining:an overview from a data base perspective显示文摘 | Chen M S Han J W Yu P S | 1996 | IEEE Transactions on Knowledge and Data Engineering1996,8,6: | 1 |
| 15 | Sol-gel deposition and luminescent properties of LaMgAl11O19:Ce^3+/Tb^3+ phosphor films 显示文摘 | JIA P Y YU M LIN J | 2005 | J Solid State Chem2005,178,9: | 1 |
| 16 | Enzymic release of reducing sugars from oat hulls by cellulase, as influenced by Aspergillus ferulic acid esterase and Trichoderma Xylanase 显示文摘 | Yu P Mckinnon J J Maenz D D | 2003 | J Agric Food Chem2003,51,: | 1 |
| 17 | Using a hash-based method with transaction trirrrning formining association rules显示文摘 | Park J S Chen M S Yu P S | 1997 | Knowledge and Data Engineering IEEE Transactions1997,9,5: | 1 |
| 18 | A gold electrode modified with self-assembled diethylenetri- aminepentaacetic acid via charge-based discrimination显示文摘 | Li J P Liu R Yu J G | 2009 | Analytical scienes2009,25,12: | 1 |
| 19 | Mechanical prope- rties of TiN thin film coatings on 304 stainless steel substrates显示文摘 | CHOU W J YU G P HUANG J H | 2002 | Serface and Coatings Technology2002,,149: | 1 |
| 20 | Factors affecting Agrobactcrium-mediated transformation and regeneration of sweet orange and citrange 显示文摘 | Yu C H Huang S Chen C X Deng Z A Ling P and Gmitter F O J | 2002 | Plant Cell Tissue and Organ Culture2002,71,: | 1 |