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1328篇 您的检索式:作者名="Yuan N"
    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
21990—2017年中国伤害负担:2017年全球疾病负担研究结果(摘译)显示文摘伤害是全球性的公共卫生挑战,涉及各年龄组和不同性别的人群。过去三十年来,中国经济快速发展,人口老龄化趋势加重,社会呈现出城镇化、机动化和老龄化等特征。随着人们生活环境和生活方式的改变,伤害已跃居人群致死原因第五位,仅排在恶性肿瘤、心脑血管疾病、呼吸系统疾病和心肌梗死之后。据估计,中国每年在伤害方面消耗的直接医疗费用约为650亿元人民币.林泽婷(译) 吕来文(译) 黄晓晴(译) 李丽萍(审校) Duan Leilei Ye Pengpeng Juanita A Haagsma Jin Ye Wang Yuan Er Yuliang Deng Xiao Gao Xin Ji Cuirong Wang Linhong Marlena S Bannick W Cli Mountjoy-Venning Caitlin N Hawley Zichen Liu Mari Smith Spencer L James Theo Vos Christopher J L Murray 2020伤害医学(电子版)2020,9,2:15
3A Critical Role of AMT2;1 in Root-To-Shoot Translocation of Ammonium in Arabidopsis显示文摘在植物根的铵举起被 AMT/MEP/Rh-type 铵 transporters 调停。从在 Arabidopsis 根被表示的五 AMT,四 AMT1 类型 transporters 而没有生理的功能到目前为止被分到属于 MEP 亚科的唯一的相当或相同的事物,贡献铵举起, AMT2; 1。基于在铵供应下面,抄本 AMT2 铺平的观察; 1 增加了,它的倡导者活动优先地变了到 pericycle,我们估计了 AMT2 的贡献; 1 到木部装载。当暴露了到 15标记 N 的铵, amt2; 1 变异的线 translocated 更少 tracer 到射击和在木部树液的包含的更少铵。而且,在 amt1 ; 1 amt1 ; 2 amt1 ; 3 amt2 ; 1 四倍的异种( qko ), AMT2 的合作表示; 1 与任何一个 AMT1 ; 2 或 AMT1 ; 3 显著地提高的 15 N translocation 到射击,显示在 AMT2 之间的一个合作行动; 1 并且 AMT1 transporters 。在 N 缺乏下面, proAMT2; 1-GFP 线在外皮的根房间主要显示出提高的倡导者活动,它与一致,提高的铵流入由 AMT2 交谈了; 1 在 millimolar 底层集中。我们的结果除了在低亲密关系的范围中等作出贡献到根举起显示那, AMT2;主要在铵的 root-to-shoot translocation 的 1 个函数,响应 ?植物取决于它的 cell-type-specific 表达式营养的地位并且到本地铵坡度。Ricardo F.H. Giehl Alberto M. Laginha Fengying Duan Doris Rentsch Lixing Yuan Nicolaus von Wirén 2017Molecular Plant2017,10,11:10
4Cultured Mycelium Cordyceps sinensis alleviates CCI4-induced liver inflammation and fibrosis in mice by activating hepatic natural killer cells显示文摘目的: 最近的证据证明有教养的菌丝体 Cordyceps sinensis (CMCS ) 有效地在老鼠免于肝纤维变性。这里,我们调查了 CMCS 的 anti-fibrotic 行动是否与它肝的生来的杀手( NK )的活动的规定有关是在 CCl 4-treated mice.Methods 的房间: C57BL/6 老鼠与10% CCl 4被注射( 2 mL/kg , ip ) 3 次每为 4 个星期的星期,并且收到了 CMCS ( 120 mg· ; kg −1·d−1, ig )在这个时期期间。在实验的另一部分,老鼠也与 NK 删除房间的抗体 ASGM-1 被注射(20 μ g, ip ) 在开始的 3 个星期内的 5 次。在老鼠被牺牲以后,浆液肝功能,和肝发炎, hydroxyproline 内容和骨胶原免职被估计。肝的 NK 房间和孤立的肝淋巴细胞上的 NKG2D (NK 房间的激活受体) 的表示的数字用流动 cytometry 被分析。在肝纸巾的 Desmin 表示和房间 apoptosis 分别地用染色的 desmin 和 TUNEL 试金被学习。α 的层次; -SMA, TGF-β, RAE-1δ并且 RAE-1ε在肝,纸巾被 RT-qPCR.Results 决定: 在 CCl 4-treated 鼠标, CMCS 管理显著地改进了肝功能,稀释的肝发炎和纤维变性,并且在肝的 NK 房间上增加了肝的 NK 房间的数字和 NKG2D 的表达式水平。而且, CMCS 管理显著地减少了在肝纸巾的 desmin 表示,和邻近肝的星形的房间的染色的增加的 TUNEL。有 NK 删除房间的 ASGM-1 的注射不仅减少在 CCl 4-treated 老鼠的肝的 NK 房间的数字,而且极大地加速的肝发炎和纤维变性。在有 NK 房间弄空的 CCl 4-treated 老鼠, CMCS 管理速度肝纤维变性开发的率,并且温和地 upregulated 肝的 NK 房间,但是没有改变 NKG2D expression.Conclusion 的数字: CMCS allevi¬经由支持肝的 NK 房间的激活的 ates CCl 4-induced 肝发炎和纤维变性。CMCS 部分颠倒肝的 NK 房间的 ASGM-1-induced 弄空。Yuan PENG Kai HUANG Li SHEN Ya n-ya n TAO Cheng-hai LIU 2016Acta Pharmacologica Sinica2016,37,2:8
5Effects of reclaimed water irrigation and nitrogen fertilization on the chemical properties and microbial community of soil显示文摘The ecological effect of reclaimed water irrigation and fertilizer application on the soil environment is receiving more attention.Soil microbial activity and nitrogen(N)levels are important indicators of the effect of reclaimed water irrigation on environment.This study evaluated soil physicochemical properties and microbial community structure in soils irrigated with reclaimed water and receiving varied amounts of N fertilizer.The results indicated that the reclaimed water irrigation increased soil electrical conductivity(EC)and soil water content(SWC).The N treatment has highly significant effect on the ACE,Chao,Shannon(H)and Coverage indices.Based on a 16S ribosomal RNA(16S rRNA)sequence analysis,the Proteobacteria,Gemmatimonadetes and Bacteroidetes were more abundant in soil irrigated with reclaimed water than in soil irrigated with clean water.Stronger clustering of microbial communities using either clean or reclaimed water for irrigation indicated that the type of irrigation water may have a greater influence on the structure of soil microbial community than N fertilizer treatment.Based on a canonical correspondence analysis(CCA)between the species of soil microbes and the chemical properties of the soil,which indicated that nitrate N(NO_3~–-N)and total phosphorus(TP)had significant impact on abundance of Verrucomicrobia and Gemmatimonadetes,meanwhile the p H and organic matter(OM)had impact on abundance of Firmicutes and Actinobacteria significantly.It was beneficial to the improvement of soil bacterial activity and fertility under 120 mg kg^(–1) N with reclaimed water irrigation.GUO Wei Mathias N Andersen QI Xue-bin LI Ping LI Zhong-yang FAN Xiang-yang ZHOU Yuan 2017Journal of Integrative Agriculture2017,16,3:7
6Complete decoding of TAL effectors for DNA recognition显示文摘Ju n jiao Yang Yuan Zhang Pengfei Yuan Yuexin Zhou Changzu Cai Qingpeng Ren Dingqiao Wen Coco Chu Hai Qi Wensheng Wei 2014Cell Research2014,24,5:3
7将安装于CON EDISON电网的带故障限流功能的高温超导电缆现状和进展显示文摘介绍了Hydra超导电缆项目的总体目标、设计准则、现状和进展,重点介绍了25 m原型电缆的结构设计、生产制造及型式试验。Maguire J Folts D Yuan J Henderson N Lindsay D Knoll D Rey C Duckworth R Gouge M Wolff Z Kurtz S 2011电网与清洁能源2011,27,5:3
8反思金融深化:新兴市场的稳定与发展显示文摘有深度和流动性良好的金融系统,加上有丰富的金融工具可抵御金融冲击,还可以增加一国金融的稳定性。但是金融发展或许存在一个边界,越过此边界进一步发展其收益或将下降。本文通过研究新兴市场发现:一、大部分新兴市场金融进一步发展仍然对经济的增长和稳定有利。二、金融发展对经济增长的促进作用是倒U型的,在越过高点之后金融深化对要素生产率的促进作用将下降。三、如果金融发展过快,快速深化的金融产业可能引发经济和金融动荡。四、提升金融稳定与金融发展之间没有太大冲突,更好的金融监管有助于提升金融稳定,促进金融发展。五、发展金融机构或金融市场不存在通用的顺序,尽管前者对经济的作用在下降而后者在上升。IMF课题组 Ratna Sahay Martin Cihak Papa N’Diaye Adolfo Barajas Ran Bi Diana Ayala Yuan Gao Annette Kyobe Lam Nguyen Christian Saborowski Katsiaryna Svirydzenka Seyed Reza Yousefi 胡妍斌 王辰 2015新金融2015,0,10:2
9Bioinspired membranes for multi-phase liquid and molecule separation显示文摘Water pollution is a serious problem around the world. It causes the lack of clean drinking water and brings risks to human health.Membrane technology has become a competitive candidate to treat the contaminated wastewater due to its high separation efficiency and low energy consumption. In this review, we introduce the recent development of several kinds of bioinspired separation membranes, involving the membrane design and applications. We emphasize the multi-phase liquid separation membranes inspired from nature with special wettability applied for oil/water separation, organic liquids mixture separation, and emulsion separation. After separating multi-phase liquids using these membranes, small molecule pollutants still exist in singlephase liquid. Therefore, we also expand the scope to small molecule-scale separation membranes, such as the nacre-like graphene oxide separation membrane and other nanofiltration membranes. Summary and outlook concerning the future development of separation membranes are also introduced briefly.Jingchong Liu Zhimin Cui Lanlan Hou Dianming Li Yuan Gao Li Shuai Jing Liu Jian Jin Nü Wang Yong Zhao 2019Science China Chemistry2019,62,1:2
10Genetic characterization of E2 gene of classical swine fever virus by restriction fragment length polymorphism and phylogenetic analysis 显示文摘CHEN N LI D YUAN X 2010Virus Genes2010,40,38:1
11Multiple solutions for quasilinear PDEs involving the critical Sobolev and Hardy exponents显示文摘Ghoussoub N Yuan C 2000Transactions of the American Mathematical Society2000,352,12:1
12Mixed Hz/H control u- sing fuzzy singularly perturbed model with multiple pertur- bation parameters for gust load alleviation 显示文摘YUAN Y HU Y N SUN F C 2011Tsinghua Science and Technology2011,16,4:1
13Outage probability of mul- tiuser relay networks in nakagami-m fading channels显示文摘N Yang M Elkashlan J H Yuan 2010IEEE Transactions on Vehicular Technology2010,59,5:1
14Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta显示文摘Yuan M Konstantopoulos N Lee J 2001Science2001,293,5535:1
15Assoeiation between carotidplaque characteristics and subsequent ischemic cerebrovascular events:a pro- spective assessment with MRI-initial results显示文摘Takaya N Yuan C Chu B 2006Stroke2006,37,3:1
16Wideband Composite AMC Surfaces for RCS Reduction 显示文摘Fu Y Q Li Y Q Yuan N C 2011Microwave and Optical Technology Letters2011,53,4:1
17Epidemiologieal survey of ossi- fication of the ligamentum flavum in thoraeic spine: CT imaging observation of 993 eases显示文摘Lang N Yuan HS Wang HL 2013Eur Spine J2013,22,4:1
18Reversal of obesity-and dietinduced insulin resistance with salicylates or targeted disruption of Ikkbeta显示文摘Yuan M Konstantopoulos N Lee J 0,,5535:1
19Valence reduction process from solgel V205 toVO2 thin film显示文摘Yuan N Li J LinC 2002ApplSurfSci2002,191,14:1
20Catalytic production of 1,2-propanediol from glycerol in bio-ethanol solvent 显示文摘Xia S X Yuan Z L Wang L N Chen P Hou Z Y 2012Bioresource Technology2012,104,:1
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