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9篇 您的检索式:作者名="Yuanfu He"
    题名 作者 年代 出处 被引量
1Size-tunable synthesis of gold nanorods using pyrogallol as a reducing agent显示文摘A novel and facile seed-mediated method for the preparation of monodispersed gold nanorods(GNRs) is presented by introducing pyrogallol as a reductant. Fast Fourier transformation of high-resolution transmission electron microscopy reveals that the synthesized GNRs are single crystalline. The longitudinal surface plasmon resonance of GNRs can be finely tuned by varying silver ion concentrations or seed amounts. Also, both thick(diameter >30 nm) and thin(diameter <10 nm) GNRs with exceptional monodispersity can be well prepared by this method. These findings indicate that this method has a greater performance in controlling the morphology of GNRs than that of traditional approach with ascorbic acid as a reductant.Yuanfu Huang Kai Xia Nongyue He Zhuoxuan Lu Liming Zhang Yan Deng Libo Nie 2015Science China Chemistry2015,58,11:3
2Application of the Multigrid Data Assimilation Scheme to the China Seas’ Temperature Forecast显示文摘Li Wei Xie Yuanfu He Zhongjie Han Guijun Liu Kexiu Ma Jirui Li Dong 2008Journal of Atmospheric and Oceanic Technology2008,,11:1
3Application of the Sequential Three-Dimensional Variational Method to Assimilating SST in a Global Ocean Model显示文摘He Zhongjie Xie Yuanfu Li Wei Li Dong Han Guijun Liu Kexiu Ma Jirui 2008Journal of Atmospheric and Oceanic Technology2008,,6:1
4Applica- tion of the sequential three-dimensional variational method to assimilating SST in a global ocean model 显示文摘HE Zhongjie XIE Yuanfu LI Dong 2008Journal of Atmospheric and Oceanic Technology2008,25,6:1
5Application of the Multigrid Data Assimilation Scheme to the China Seas’ Temperature Forecast显示文摘Li Wei Xie Yuanfu He Zhongjie Han Guijun Liu Kexiu Ma Jirui Li Dong Journal of Atmospheric and Oceanic Technology0,,:1
6Application of the Sequential Three-Dimensional Variational Method to Assimilating SST in a Global Ocean Model显示文摘He Zhongjie Xie Yuanfu Li Wei Li Dong Han Guijun Liu Kexiu Ma Jirui Journal of Atmospheric and Oceanic Technology0,,:1
7Perivascular localized cells commit erythropoiesis in PDGF-B-expressing solid tumors显示文摘Background:Tumors possess incessant growth features,and expansion of their masses demands sufficient oxygen supply by red blood cells(RBCs).In adult mammals,the bone marrow(BM)is the main organ regulating hematopoiesis with dedicated manners.Other than BM,extramedullary hematopoiesis is discovered in various pathophysiological settings.However,whether tumors can contribute to hematopoiesis is completely unknown.Accumulating evidence shows that,in the tumor microenvironment(TME),perivascular localized cells retain progenitor cell properties and can differentiate into other cells.Here,we sought to better understand whether and how perivascular localized pericytes in tumors manipulate hematopoiesis.Methods:To test if vascular cells can differentiate into RBCs,genome-wide expression profiling was performed using mouse-derived pericytes.Genetic tracing of perivascular localized cells employing NG2-CreERT2:R26R-tdTomato mouse strain was used to validate the findings in vivo.Fluorescence-activated cell sorting(FACS),single-cell sequencing,and colony formation assays were applied for biological studies.The production of erythroid differentiationspecific cytokine,erythropoietin(EPO),in TME was checked using quantitative polymerase chain reaction(qPCR),enzyme-linked immunosorbent assay(ELISA,magnetic-activated cell sorting and immunohistochemistry.To investigate BM function in tumor erythropoiesis,BM transplantation mouse models were employed.Results:Genome-wide expression profiling showed that in response to plateletderived growth factor subunit B(PDGF-B),neural/glial antigen 2(NG2)+perivascular localized cells exhibited hematopoietic stem and progenitor-like features and underwent differentiation towards the erythroid lineage.PDGF-B simultaneously targeted cancer-associated fibroblasts to produce high levels of EPO,a crucial hormone that necessitates erythropoiesis.FACS analysis using genetic tracing of NG2+cells in tumors defined the perivascular localized cell-derived subpopulation of hematopoietic cells.Single-cell sequencing and colony formation assays validated the fact that,upon PDGF-B stimulation,NG2+cells isolated from tumors acted as erythroblast progenitor cells,which were distinctive from the canonical BM hematopoietic stem cells.Conclusions:Our data provide a new concept of hematopoiesis within tumor tissues and novel mechanistic insights into perivascular localized cell-derived erythroid cells within TME.Targeting tumor hematopoiesis is a novel therapeutic concept for treating various cancers that may have profound impacts on cancer therapy.Kayoko Hosaka Chenchen Wang Shiyue Zhang Xue Lv Takahiro Seki Yin Zhang Xu Jing Jieyu Wu Qiqiao Du Xingkang He Yulong Fan Xuan Li Makoto Kondo Masahito Yoshihara Hong Qian Lihong Shi Ping Zhu Yuanfu Xu Yunlong Yang Tao Cheng Yihai Cao 2023Cancer Communications2023,43,6:1
8MoP QDs@graphene as highly efficient electrocatalyst for polysulfide conversion in Li-S batteries显示文摘The shuttle effect of lithium polysulfides(LiPSs)and sluggish redox conversion significantly hinder practical implementation of lithium-sulfur batteries(LSBs).To overcome these issues,herein,we present MoP quantum dots anchored N,P-doped graphene(MPQ@G)as a multifunctional LSB cathode.The N,P-doped graphene layers serve as a conductive skeleton to support the MoP QDs which can accelerate the electron transfer,physically hinder the polysulfide migration and thus enhance the electrochemical performance.More importantly,as a polar and conductive catalyst,MoP QDs provide catalytically active sites for the conversion of LiPSs.As a result,the LSBs with MPQ@G/S cathodes deliver an elevated initial capacity of 1220.2 mAh g~(-1)at 0.2 C and remain 98.9%after rate cycles,signifying its exceptional cycling stability.Moreover,it displays a large capacity of 681.2 mAh g~(-1)even at a high rate of 1 C.The Li-S pouch cell also presents high specific capacities and preeminent cycling stabilities,confirming its great potential for high-rate applications.Density functional theory calculations demonstrate the improved absorptivity and redox conversion reversibility of LiPSs.This work provides an efficient strategy to improve composite with highly adsorptive and catalytic properties for high-performance Li-S batteries.Bo Yu Fei Ma Dongjiang Chen Katam Srinivas Xiaojuan Zhang Xinqiang Wang Bin Wang Wanli Zhang Zegao Wang Weidong He Yuanfu Chen 2021Journal of Materials Science & Technology2021,,31:1
9Aφ6-m Tunnel Boring Machine Steel Arch Splicing Manipulator显示文摘Robotic splicing of steel arches is a challenging task that is necessary to realize the grasping and docking of steel arches in a limited space.Steel arches often have a mass of more than 200 kg and length of more than 4 m.Owing to the large volume and mass of steel arches and the high requirements for accurately positioning the splicing,it is difficult for a general manipulator to meet the stiffness requirements.To enhance the structural stiffness of the steel arch splicing manipulator,a single-degree-of-freedom(DOF)closed-loop mechanism was added to the grasping structure of the manipulator.Based on the basic principle of structural synthesis,a solution model of the single-DOF closed-loop mechanism was developed,and alternative kinematic pairs of the mechanism with different input constraints and output requirements were derived.Based on this model,a design method for a single-DOF closed-loop grasping mechanism and a posture adjustment mechanism for a steel arch was devised.Combined with the same dimensional subspace equivalence principle of the graphical-type synthesis method,12 types of steel arch splicing manipulator were constructed.By analyzing the motion/force transmission and structural complexity of the steel arch splicing manipulators,the best scheme was selected.A prototype of the steel arch splicing manipulator was manufactured.Adams software was used to obtain clearly the output trajectory of the end of the manipulator.The relative spatial positions of the upper and lower jaws under different working stages were analyzed,demonstrating that the manipulator satisfied the grasping requirements.Through a steel arch splicing experiment,the grasping effect,docking accuracy,and splicing efficiency of the manipulator met the design requirements.The steel arch splicing manipulator can replace the manual completion of the steel arch splicing operation,significantly improving the operation efficiency.Yuanfu He Yimin Xia Zhen Xu Jie Yao Bo Ning Xuemeng Xiao 2022Chinese Journal of Mechanical Engineering2022,35,2:0
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