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| 1 | Reactive mesoporous silica nanoparticles loaded with limonene for improving physical and mental health of mice at simulated microgravity condition显示文摘Astronauts are under high stress for a long time because of the microgravity condition,which leads to anxiety,affects their learning and memory abilities,and seriously impairs the health of astronauts.Aromatherapy can improve the physical and mental health of astronauts in a way that moisturizes them softly and silently.However,the strong volatility of fragrances and inconvenience of aroma treatment greatly limit their application in the field of spaceflight.In this study,reactive mesoporous silica nanoparticles were prepared to encapsulate and slowly release limonene.The limonene loaded nanoparticles were named limonene@mesoporous silica nanoparticles-cyanuric chloride(LE@MSNs-CYC).LE@MSNs-CYC were then applied to wallpaper to improve the convenience of aromatherapy.LE@MSNs-CYC could chemically react with the wallpaper,thus firmly adsorbed on the wallpaper.In the following,the mice were treated with hindlimb unloading(HU)to simulate a microgravity environment.The results showed that 28-day HU led to an increase in the level of anxiety and declines in learning,memory,and physical health in mice.LE@MSNs-CYC showed significant relief effects on anxiety,learning,memory,and physical health of HU treated mice.Subsequently,the molecular mechanisms were explored by hypothalamic-pituitary-adrenal axis related hormones,immune-related cytokines,learning,and memory-related neurotransmitters and proteins. | Zhiguo Lu Jianze Wang Lina Qu Guanghan Kan Tianlu Zhang Jie Shen Yan Li Jun Yang Yunwei Niu Zuobing Xiao Yinghui Li Xin Zhang | 2020 | Bioactive Materials2020，5，4： | 5 |
| 2 | Large-scale achromatic flat lens by light frequency-domain coherence optimization显示文摘Flat lenses,including metalens and diffractive lens,have attracted increasing attention due to their ability to miniaturize the imaging devices.However,realizing a large scale achromatic flat lens with high performance still remains a big challenge.Here,we developed a new framework in designing achromatic multi-level diffractive lenses by light coherence optimization,which enables the implementation of large-scale flat lenses under non-ideal conditions.As results,a series achromatic polymer lenses with diameter from 1 to 10mm are successfully designed and fabricated.The subsequent optical characterizations substantially validate our theoretical framework and show relatively good performance of the centimeter-scale achromatic multi-level diffractive lenses with a super broad bandwidth in optical wavelengths(400-1100 nm).After comparing with conventional refractive lens,this achromatic lens shows significant advantages in white-light imaging performance,implying a new strategy in developing practical planar optical devices. | Xingjian Xiao Yunwei Zhao Xin Ye Chen Chen Xinmou Lu Yansen Rong Junhong Deng Guixin Li Shining Zhu Tao Li | 2022 | Light(Science & Applications)2022，11，12： | 2 |
| 3 | Mesoporous silica nanospheres with the ability of photo-driven releasing sandela 803 for the application to wallpaper显示文摘Fragrances are widely used in our daily life and have made great contributions to creating a clean and fresh healthy air environment. However, the rapid volatilization severely influences their storage,application and quality. Therefore, it is necessary and urgent to develop approaches to controllably release the odorants as demanded. In this study, photo-driven mesoporous silica nanospheres loaded with sandela 803 was designed, prepared and named as S803@MS-S. S803@MS-S possessed ordered mesoporous, large specific surface area and pore volume. After adsorption of sandela 803, the S803@MSS was added into wallpaper to prepare fragrant wallpaper S803@MS-S-W. And this wallpaper exhibited excellent sustained and controlled release performances stimulated by light. | Weihong Ji Tianlu Zhang Zhiguo Lu Jie Shen Jing Hu Yunwei Niu Zuobing Xiao Xin Zhang | 2019 | Chinese Chemical Letters2019，30，3： | 1 |
| 4 | Preparation of hollow mesoporous silica nanorods for encapsulating and slowly releasing eugenol显示文摘Fragrances are widely used in many aspects of our lives.They cannot only make people happy,but also treat many diseases.However,excessively fast evaporation rate is one of the main obstacles to the use of spices.In this study,mesoporous silica nanorods(MSNRs)and hollow mesoporous silica nanorods(HMSNRs)were prepared to encapsulate eugenol.These two nano-fragrances were named eugenol@MSNRs and eugenol@HMSNRs,respectively.The morphologies,size,interior structures and pore performances of MSNRs and HMSNRs.Besides,the performances of encapsulation and fragrance release of eugenol@MSNRs and eugenol@HMSNRs were compared and analyzed.The results showed that eugenol@HMSNRs encapsulated more fragrance and were faster to encapsulate compared with eugenol@MSNRs.Both the release rates of eugenol from eugenol@MSNRs and eugenol@HMSNRs were slow.But the eugenol was released from eugenol@MSNRs more slowly. | Tianlu Zhang Zhiguo Lu Luyao Zhang Yan Li Jun Yang Jie Shen Jianze Wang Yunwei Niu Zuobing Xiao Lei Chen Xin Zhang | 2020 | Chinese Chemical Letters2020，31，12： | 0 |
| 5 | Cationic and temperature-sensitive liposomes loaded with eugenol for the application to silk显示文摘Silk has been widely used in the clothing industry due to their soft and smooth features,good biocompatibility,good heat dissipation,warmth and ultraviolet resistance.The application of fragrance to silk can significantly improve the performance of silk.However,there are two key scientific problems that need to be solved:slowing down the release rate of fragrances and increasing the scent lasting time of silk.In this study,cationic and temperature-sensitive liposomes were designed and prepared to encapsulate eugenol.These fragrance-loaded liposomes significantly slowed down the release rate of the fragrance and controlled the release rate of the fragrance in a thermo-sensitive manner.The liposomes adhered to the silk through electrostatic adsorption interaction.The positive charge on the fragranceloaded liposomes neutralized much negative charge on silk and thereby increasing the adhesion efficiency. | Zhiguo Lu Xiangyu Wang Tianlu Zhang Luyao Zhang Jun Yang Yan Li Jie Shen Jianze Wang Yunwei Niu Zuobing Xiao Guiying Liu Xin Zhang | 2020 | Chinese Chemical Letters2020，31，12： | 0 |
| 6 | Evaluation of High Step-up Power Conversion Systems for Large-capacity Photovoltaic Generation Integrated into Medium Voltage DC Grids显示文摘With the increase of dc based renewable energy generation and dc loads,the medium voltage dc(MVDC)distribution network is becoming a promising option for more efficient system integration.In particular,large-capacity photovoltaic(PV)-based power generation is growing rapidly,and a corresponding power conversion system is critical to integrate these large PV systems into MVDC power grid.Different from traditional ac grid-connected converters,the converter system for dc grid interfaced PV system requires large-capacity dc conversion over a wide range of ultra-high voltage step-up ratios.This is an important issue,yet received limited research so far.In this paper,a thorough study of dc-dc conversion system for a medium-voltage dc grid-connected PV system is conducted.The required structural features for such a conversion system are first discussed.Based on these features,the conversion system is classified into four categories by series-parallel connection scheme of power modules.Then two existing conversion system configurations as well as a proposed solution are compared in terms of input/output performance,conversion efficiency,modulation method,control complexity,power density,reliability,and hardware cost.In-depth analysis is carried out to select the most suitable conversion systems in various application scenarios. | Shilei Lu Kai Sun Haixu Shi Yunwei Li Guoen Cao | 2021 | Chinese Journal of Electrical Engineering2021，7，4： | 0 |
| 7 | Reactive nano-essential oils for sustained release of essential oils and application to wallpaper显示文摘Essential oils are a volatile and aromatic substance with a variety of active biological activities.However,the excessive volatility and inconvenience of the use of essential oils limit their applications.In this study,we developed a reactive mesoporous silica nanoparticle(rMSNs)based on cyanuric chloride modification for essential oil encapsulation and commodity adhesion.The large pore volume and specific surface area of rMSNs facilitate the nanoparticles adhering to a large amount of essential oil and achieve the sustained release of essential oil,thus prolonging the fragrance retention time of essential oils.The reactive nanoessential oils can form covalent bonds with the wallpaper,thereby remarkably improving the adhesion of the reactive nano-essential oils on the wallpaper and preventing the reactive nano-essential oil from deadhering from the wallpaper.The active nano essential oil simultaneously overcomes the intense volatility of the essential oil and inconvenience in use,has a simple preparation process and low cost,and has great application potential. | Qiulian Hao Huan Peng Ruichen Zhao Jianze Wang Zhiguo Lu Jingwen Wang Jie Shen Yunwei Niu Zuobing Xiao Guiying Liu Jifu Hao Xin Zhang | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 8 | Research Trends and Emerging Hotspots of Lung Cancer Surgery during 2012-2021:A 10-Year Bibliometric and Network Analysis显示文摘Background. Lung cancer remains the leading cause of death because of cancer globally in the past years. To inspire researcherswith new targets and path-breaking directions for lung cancer research, this study is aimed at exploring the research trends andemerging hotspots in the lung cancer surgery literature in the recent decade. Methods. This cross-sectional study combinedbibliometric and network analysis techniques to undertake a quantitative analysis of lung cancer surgery literature. Dimensionsdatabase was searched using keywords in a 10-year period (2012-2021). Publications were characterized by publication year,research countries, field citation ratio, cooperation status, research area, and emerging hotspots. Results. Overall, globalscholarly outputs of lung cancer surgery had almost doubled during the recent decade, with China, Japan, and the UnitedStates leading the way, while Denmark and Belgium predominated in terms of scientific influence. Network analysis showedthat international cooperation accounted for a relatively small portion in lung cancer surgery research, and the United States,China, and Europe were the prominent centers of international cooperation network. In the recent decade, research of lungcancer surgery majored in prevention, biomedical imaging, rehabilitation, and genetics, and the emerging research hotspotstransformed into immunotherapy. Research on immunotherapy showed a considerable increase in scientific influence in thelatest year. Conclusions. The study findings are expected to provide researchers and policymakers with interesting insights intothe changing trends of lung cancer surgery research and further generate evidence to support decision-making in improvingprognosis for patients with lung cancer. | Jingyi Wu Chenlu Bao Ganwei Liu Shushi Meng Yunwei Lu Pengfei Li Jian Zhou | 2022 | Health Data Science2022，，1： | 0 |
| 9 | Feature Preserving Milli-Scaling of Large Format Visualizations显示文摘Ultra-scale data analysis has created many new challenges for visualization.For example,in climate research with two-dimensional time-varying data,scientists find it crucial to study the hidden temporal relationships from a set of large scale images,whose resolutions are much higher than that of general computer monitors.When scientists can only visualize a small portion(< 1=1000) of a time step at one time,it is extremely challenging to analyze the temporal features from multiple time steps.As this problem cannot be simply solved with interaction or display technologies,this paper presents a milli-scaling approach by designing downscaling algorithms with significant ratios.Our approach can produce readable-sized images of multiple ultra-scale visualizations,while preserving important data features and temporal relationships.Using the climate visualization as the testing application,we demonstrate that our approach provides a new tool for users to effectively make sense of multiple,large-format visualizations. | Yunwei Zhang Aidong Lu Jian Huang | 2012 | Tsinghua Science and Technology2012，17，4： | 0 |
| 10 | Preparation of mesoporous silica nanoparticle with tunable pore diameters for encapsulating and slowly releasing eugenol显示文摘Fragrances are frequently added to a variety of products,including food,cosmetics and health products.However,the high volatility and instability of essence limit its application in some fields.In this study,mesoporous silica nanoparticles(MSNs) were prepared to encapsulate eugenol,which could reduce the volatilization of the fragrance molecules.A facile approach was presented to synthesize MSNs with three different pore diameters for encapsulating eugenol.In addition,the properties of MSNs including mean particle size,morphology,encapsulating efficiency and release tendency were charac terized.Results showed that the larger the pore diameters of MSNs,the more aromatic molecules were adsorbed.Furthermore,the release mechanism was described as the smaller the pore diameters of MSNs,the slower the release of eugenol. | Tianlu Zhang Zhiguo Lu Jianze Wang Jie Shen Qiulian Hao Yan Li Jun Yang Yunwei Niu Zuobing Xiao Lei Chen Xin Zhang | 2021 | Chinese Chemical Letters2021，32，5： | 0 |
| 11 | Zwitterionic comb-like lipid polymers encapsulating linalool for increasing the fragrance retention time显示文摘Fragrances are widely used in cosmetics,apparel and detergents.However,the rapid evaporation of the aro ma shortens the useful life of the aromatic product.Therefore,improving the fragrance retention time of aromatic products and prolonging the service life of aromatic products are the key scientific problems that need to be solved in current aromatic products.In this study,zwitterionic comb-like lipid polymers were synthesized to encapsulate the fragrance molecule linalool.The results showed that the zwitterionic comb lipid molecules were capable of encapsulating more linalool than linear lipid molecules.At the same time,the zwitterionic comb-like lipid molecules also limited the slow release rate of the aroma,thereby increasing the fragrance retention time of the nano-fragrance. | Tianlu Zhang Zhiguo Lu Xiangyu Wang Jie Shen Jianze Wang Yunwei Niu Zuobing Xiao Xin Zhang | 2021 | Chinese Chemical Letters2021，32，1： | 0 |
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