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| 1 | Characterization of event-related potentials in obsessive compulsive disorder patients: Comparison with depression and generalized anxiety disorder patients显示文摘BACKGROUND: Study results of event-related potential in obsessive compulsive disorder (OCD) remain controversial, potentially as a result of different instruments utilized and their differing technical characteristics. OBJECTIVE: To investigate the differences in several common event-related potentials, i.e. contingent negative variations, P300, and mismatch negativity (MMN), in OCD patients, depression patients, generalized anxiety disorder (GAD) patients, and healthy controls. DESIGN, TIME AND SETTING: A case-control study was performed in the Department of Electrophysiology, Shanghai Mental Health Center from May 2002 to December 2005. PARTICIPANTS: A total of 38 OCD patients, 20 depression patients, and 18 GAD patients, who were diagnosed according to the criteria of Chinese Classification of Mental Disorders (Version 3), formulated by the Chinese Psychiatry Association, were selected from the Outpatient Department o Shanghai Mental Health Center. Patients with two or more the above diseases were excluded. In addition, 28 healthy people, gender and age matched, were selected as controls. METHODS: Contingent negative variations, P300, and MMN were recorded by a Nicolet Spirit Instrument. All electrodes were attached at Cz according to the International 10-20 system, with the mastoid leads as reference and Fpz as ground. MAIN OUTCOME MEASURES: Amplitude and latency of contingent negative variations, P300, and MMN. RESULTS: The contingent negative variations, P300, and MMN were different (P < 0.01). OCD patients showed an increased M1 amplitude compared with controls, depression, and GAD patients (P < 0.01). Target P300 amplitudes were significantly lower in OCD, depression, and GAD patients compared with controls (P < 0.01). Moreover, N2 latency and latency of MMN were prolonged in OCD and depression groups compared with controls (P < 0.05). CONCLUSION: Event-related potentials were different in depression, GAD, and OCD patients and healthy controls. In particular, OCD patients exhibited unique characteristics. | Yingzhi Lu Wenbin Zong Hanzhen Dong Faxin Wang Jinyu PU Xingshi Chen Yunxiang Tang | 2010 | Neural Regeneration Research2010，5，12： | 5 |
| 2 | Loss of heterozygosity by SCRaMbLEing显示文摘Genetic variation drives phenotypic evolution within populations. Genetic variation can be divided into different forms according to the size of genomic changes. However, study of large-scale genomic variation such as structural variation and aneuploidy is still limited and mainly based on the static, predetermined feature of individual genomes. Here, using SCRaMbLE,different levels of loss of heterozygosity(LOH) events including short-range LOH, long-range LOH and whole chromosome LOH were detected in evolved strains. By contrast, using rapid adaptive evolution, aneuploidy was detected in the adaptive strains. It was further found that deletion of gene GLN3, long-range LOH in the left arm of synthetic chromosome Ⅹ, whole chromosome LOH of synthetic chromosome Ⅹ, and duplication of chromosome Ⅷ(trisomy) lead to increased rapamycin resistance in synthetic yeast. Comparative analysis of genome stability of evolved strains indicates that the aneuploid strain has a higher frequency of degeneration than the SCRaMbLEd strain. These findings enrich our understanding of genetic mechanism of rapamycin resistance in yeast, and provide valuable insights into yeast genome architecture and function. | Yunxiang Li Yi Wu Lu Ma Zhou Guo Wenhai Xiao Yingjin Yuan | 2019 | Science China(Life Sciences)2019，62，3： | 4 |
| 3 | Effects of sleep deprivation on polysomnography and executive function in patients with depression显示文摘 | Lu Yingzhi Ren Qingtao Zong Li Wu Yingli Zhang Qinfeng Ma Xiuqing Pu Jinyu Dong Hanzhen Liu Qingqing Tang Yunxiang Song Lisheng Chen Xingshi Pan Xiao Cui Yi | 2014 | Chinese Medical Journal2014，，18： | 2 |
| 4 | Enhanced tribological properties of aligned graphene-epoxy composites显示文摘The random distribution of graphene in epoxy matrix hinders the further applications of grapheneepoxy composites in the field of tribology.Hence,in order to fully utilize the anisotropic properties of graphene,highly aligned graphene-epoxy composites(AGEC)with horizontally oriented structure have been fabricated via an improved vacuum filtration freeze-drying method.The frictional tests results indicated that the wear rate of AGEC slowly increased from 5.19x10^(-6)mm^(3)/(N-m)to 2.87x10^(-5)mm^(3)/(N-m)with the increasing of the normal load from 2 to 10 N,whereas the friction coefficient(COF)remained a constant of 0.109.Compared to the neat epoxy and random graphene-epoxy composites(RGEC),the COF of AGEC was reduced by 87.5%and 71.2%,and the reduction of wear rate was 86.6%and 85.4%at most,respectively.Scanning electron microscope(SEM)observations illustrated that a compact graphene self-lubricant film was formed on the worn surface of AGEC,which enables AGEC to possess excellent tribological performance.Finally,in light of the excellent tribological properties of AGEC,this study highlights a pathway to expand the tribological applications of graphene-epoxy composites. | Yuefeng DU Zhenyu ZHANG Dong WANG Lezhen ZHANG Junfeng CUI Yapeng CHEN Mingliang WU Ruiyang KANG Yunxiang LU Jinhong YU Nan JIANG | 2022 | Friction2022，10，6： | 2 |
| 5 | Influence of TiO2/Sb2O3 ratio on ZnO varistor ceramics显示文摘 | Zhang Congchun Hu Yunxiang Lu Wenzhkong | 2002 | Journal of the European Ceramic Society2002，22，： | 1 |
| 6 | Influence of TiO2/Sb2O3 ratio on ZnO varistor ceramics 显示文摘 | ZHANG Congchun HU Yunxiang LU Wenzhong | 2002 | J Eur Ceram Soe2002，22，： | 1 |
| 7 | Flutter analysis of compressor blades under travelling wave modes using an efficient fluid–structure interaction method显示文摘Flutter is a self-sustained vibration which could create serious damage to compressor blades.Improving the efficiency and accuracy of Fluid-Structure Interaction(FSI)method is crucial to flutter analysis.An efficient FSI method which combines a fast mesh deformation technology and Double-Passage Shape Correction(DPSC)method is proposed to predict blades flutter under traveling wave modes.Firstly,regarding the fluid domain as a pseudo elastic solid,the flow mesh deformation and blade vibration response can be quickly obtained by solving the governing equations of the holistic system composed of blade and pseudo elastic solid.Then,by storing and updating the Fourier coefficients on the circumferential boundary,the phase-lagged boundary condition is introduced into the computational domain.Finally,the aerodynamic stability for the blades of an axial compressor under various Inter-Blade Phase Angle(IBPA)is analyzed.The results show that the proposed method can effectively predict the characteristics of aerodynamic damping,aerodynamic force and blade displacement.And a conceptual model is proposed to describe the motion behavior of the shock wave.Compared with the multi-passage method,the proposed method obtains almost the same unstable IBPA interval and the blade displacement error is less than 3.4%.But the calculation time is significantly shortened especially in small IBPA cases. | Kangdi LI Yunxiang DU Zili XU Shizhi ZHAO Lu CHENG | 2023 | Chinese Journal of Aeronautics2023，36，11： | 0 |
| 8 | Unprecedented differences in the diamond nucleation density between carbon-and silicon-faces of 4H-silicon carbides显示文摘4H-silicon carbides deposited by diamond films have wide applications in many fields such as semiconductor heterojunction,heat sink and mechanical sealing.Nucleation plays a critical role in the deposition of the diamond film on 4H-silicon carbides.Nevertheless,as a typical polar material,the fundamental mechanism of diamond nucleation on different faces of 4H-silicon carbides has not been fully understood yet.In this contribution,nucleation of diamond was performed on the carbon-and silicon-faces of 4H-silicon carbides in a direct current chemical vapor deposition device.The nucleation density on the carbon-face is higher by 2-3 orders of magnitude compared to the silicon-face.Transmission electron microscopy verifies that there are high density diamond nuclei on the interface between the carbon-face and the diamond film,which is different from columnar diamond growth structure on the silicon-face.Transition state theory calculation reveals that the unprecedented distinction of the nucleation density between the carbon-face and the silicon-face is attributed to different desorption rates of the absorbed hydrocarbon radicals.In addition,kinetic model simulations demonstrate that it is more difficult to form CH2(s)-CH2(s)dimers on silicon-faces than carbon-faces,resulting in much lower nucleation densities on silicon-faces. | Bo Wang Pitsiri Sukkaew Guichen Song Andreas Rosenkranz Yunxiang Lu Kazhihito Nishimura Jia Wang Jilei Lyu Yang Cao Jian Yi Lars Ojamae He Li Nanjiang | 2020 | Chinese Chemical Letters2020，31，7： | 0 |
| 9 | PtCu-SnO_(2)nanocomposites for ultrasensitive and rapid ultra-low formaldehyde sensing显示文摘SnO 2 nanospheres with diameters of 30∼50 nm and Pt x Cu 1-x bimetallic nanoparticles with sizes of approxi-mately 10 nm were synthesized via hydrothermal and solvothermal methods,respectively.The Pt x Cu 1-x bimetal-lic nanoparticles were impregnated on the surface of the SnO 2 spheres to form Pt x Cu 1-x-SnO 2 nanocomposites.By varying the atomic ratios between platinum(Pt)and copper(Cu),we found that Pt 0.75 Cu 0.25-SnO 2,with a large specific surface area of 89.21 m 2/g,enabled the selective and accurate detection of low-concentration formalde-hyde compared to other metal-deposited samples and pure SnO 2.The response value of Pt 0.75 Cu 0.25-SnO 2 to 500×10−9 formaldehyde was approximately 20 at an operating temperature of 160◦C with an extremely high-speed response(15 s).The porous structures with large specific surface areas,as well as the improved catalytic effects of Pt 0.75 Cu 0.25,comprehensively contributed to the enhanced sensing performance towards formaldehyde. | Zejun Han Yunxiang Tang Guixia Lu Yuan Qi Hao Wu Zhengyi Yang Hecheng Han Xue Zhang Lili Wu Zhou Wang Jiurong Liu Fenglong Wang | 2022 | ChemPhysMater2022，1，3： | 0 |
| 10 | Development of organelle single nucleotide polymorphism (SNP) markers and their application for the identification of cytoplasmic inheritance patterns in Pyropia yezoensis (Bangiales,Rhodophyta)显示文摘The genus Pyropia contains several important cultivated species.Genetic research in nori species has mainly focused on the cell nucleus,with few studies on organelles(chloroplast and mitochondria).Due to the high copy numbers of organelles in cells,which influence the development and traits of algae,it is necessary to study their genetic mechanism.In this study,the marine red alga Pyropia yezoensis,an important economic macroalga,was selected as the study object.To investigate organelle(chloroplast and mitochondria)inheritance in P.yezoensis,the wild type RZ(maternal strain)was crossed with the red mutant HT(paternal strain)and 30 color-sectors from 11 F1 gametophytic blades were examined.The complete chloroplast and mitochondrial genomes of the red mutant(HT)were assembled for the first time.One reliable and stable single nucleotide polymorphism(SNP)loci filtrated by bioinformatics analysis was used as a molecular marker for chloroplast and mitochondrial DNA,respectively,in subsequent experiments.PCR amplification and sequence analysis showed that the haplotypes of color-sectors detected were consistent with those of the maternal parent,confirming that both chloroplast and mitochondrial genomes were inherited maternally in P.yezoensis.The inheritance pattern of organelles in P.yezoensis can be used to guide the hybridization and breeding of nori.Additionally,the organelle SNP markers developed in this study can be applied in subsequent genetic research. | Lu WANG Junhao WANG Yunke ZHU Zhengcai CUI Fanna KONG Xianghai TANG Yunxiang MAO | 2021 | Journal of Oceanology and Limnology2021，39，4： | 0 |
| 11 | Construction of high-density genetic linkage map of Pyropia yezoensis(Bangiales,Rhodophyta)and identifi cation of red color trait QTLs in the thalli显示文摘Pyropia yezoensis is an important macroalga because of its extensive global distribution and economic importance.Color is an important trait in the thalli of P.yezoensis,it is also an effective marker to identify the hybridization in genetic breeding.In this study,a high-density genetic linkage map was constructed based on high-throughput single nucleotide polymorphism(SNP)markers,and used for analyzing the quantitative trait loci(QTLs)of red color trait in the thalli of P.yezoensis.The conchospore undergoes meiosis to develop into an ordered tetrad,and each cell has a haploid phenotype and can grow into a single individual.Based on this theory,F1 haploid population was used as the mapping population.The map included 531 SNP markers,394.57 cM long on average distance of 0.74 cM.Collinear analysis of the genetic linkage map and the physical map indicated that the coverage between the two maps was 79.42%.Furthermore,QTL mapping identified six QTLs for the chromosomal regions associated with the red color trait of the thalli.The value of phenotypic variance explained(PVE)by an individual QTL ranged from 4.71%-63.11%.And QTL qRed-1-1,with a PVE of 63.11%,was considered the major QTL.Thus,these data may provide a platform for gene and QTL fine mapping,and marker-assisted breeding in P.yezoensis in the future. | Lu WANG Kuipeng XU Xianghai TANG Junhao WANG Fanna KONG Yunxiang MAO | 2021 | Journal of Oceanology and Limnology2021，39，3： | 0 |
| 12 | Synergistic Effect of Platinum Single Atoms and Nanoclusters Boosting Electrocatalytic Hydrogen Evolution显示文摘Maximizing atomic utilization of precious metalbased catalysts is of great significance in heterogeneous catalysis,also becoming a useful strategy to develop efficient electrocatalysts for hydrogen evolution reaction(HER).Although the dispersion of platinum(Pt)as single atoms(SAs)has increasingly been used in the design of HER electrocatalysts,it is still controversial if the SAs possess higher reactivity relative to the nanoparticles with identical atom loading. | Yihui Zhu Pengfei Tian Hongliang Jiang Jingren Mu Lu Meng Xiaozhi Su Yu Wang Yunxiang Lin Yihua Zhu Li Song Chunzhong Li | 2021 | CCS Chemistry2021，3，10： | 0 |
| 13 | CO_2 capture through halogen bonding: A theoretical perspective显示文摘Halogen bonding interactions between several halogenated ion pairs and CO2 molecules have been investigated by means of density functional theory calculations. To account for the influence of solvent environment, the implicit polarized continuum model was also employed. The bromide and iodide cations of ionic liquids (ILs) under study can interact with CO2 molecules via X O interactions, which become much stronger in strength than those in the complexes of iodo-perfluorobenzenes, very effective halogen bond donors, with CO2 molecules. Such interactions, albeit somewhat weaker in strength, are also observed between halogenated ion pairs and CO2 molecules. Thus, the solubility of CO2 may be improved when using halogenated ILs, as a result of the formation of X O halogen bonds. Under solvent effects, the strength of the interactions tends to be weakened to some degree, with a concomitant elongation of intermolecular distances. The results presented here would be very useful in the design and synthesis of novel and potent ILs for CO2 physical absorption. | LI HaiYing LU YunXiang ZHU Xiang PENG ChangJun HU Jun LIU HongLai HU Ying | 2012 | Science China Chemistry2012，55，8： | 0 |
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